Clinical trials: Guideline Adherence
Diabetes Type 2, Renal Failure
A Study of the Usefulness & Usability of a Healthcare IT System for Managing Multi-morbidity and Poly-pharmacy
To assess the acceptability of a personalised ICT tool that facilitates coordinated care planning, treatment optimisation and patient self-management for patients with multiple long term conditions and their team of health…
- Conditions
- Diabetes Type 2, Renal Failure, Heart Failure, Depression
- Trial name
- C3-Cloud (NCT03834207)
- Testing
- Use of the C3-Cloud IT system
- Where
- 3 sites in Spain, Sweden and 1 more
- Volunteers
- 672 people
- Sponsor
- Dr Christopher Marguerie
Community Acquired Pneumonia
A Registry Study on Hospitalized Patients With Community-acquired Pneumonia in Real-life of China
The purpose of this study is to evaluate the disease burden of hospitalized patients with CAP and HCAP in real life of China
- Trial name
- CAP-China (NCT02492425)
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Capital Medical University
Cardiovascular Diseases, Hypercholesterolemia
Guideline Adherence for Heart Health
This study addresses the challenges associated with implementation of clinical practice guidelines (CPG's) and is motivated by our interest in gaining insight regarding the following general research questions about CPG…
- Conditions
- Cardiovascular Diseases, Hypercholesterolemia, Hypertension
- Trial name
- GLAD Heart (NCT00224848)
- Testing
- Palm-Pilot Intervention
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Sepsis
Sepsis at Södersjukhuset-Adherence to Treatment Guidelines
A retrospective single-center study with patients with suspected sepsis admitted to the Emergency Department at Södersjukhuset during a period of two years.
- Trial name
- NCT04055727
- Where
- Sweden
- Volunteers
- 11,000 people
- Sponsor
- Karolinska Institutet
Heart Failure
Evaluating Adherence to Guideline-Directed Medical Therapy in Patients With Advanced Heart Failure
A Prospective Observational, Multi-Center, Real-World Pharmacological Study Evaluating Adherence to Guideline-Directed Medical Therapy Using the Four-Pillar Strategy in Patients with Advanced Heart Failure
- Trial name
- ad-HUB (NCT07560982)
- Testing
- GDMT, Quality of life questionnaire
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Università Vita-Salute San Raffaele
Chronic Renal Insufficiency
Chronic Kidney Disease (CKD) Guideline Adherence - A Quality Improvement Study
Chronic kidney disease (CKD) is defined as kidney damage for greater than 3 months or a glomerular filtration rate less than 60 mL/min per 1.73m2 for greater than 3 months.
- Trial name
- NCT00921687
- Testing
- Education only, Multifactorial intervention
- Where
- United States
- Volunteers
- 781 people
- Sponsor
- Louis Stokes VA Medical Center
Atrial Fibrillation
Stroke Prevention and Rhythm Control Therapy STEEER-AF
A prospective trial with hospitals/health centres across 6 different European countries, being randomised to either a structured education programme as the intervention or no additional education as the control.
- Trial name
- STEEER-AF (NCT04396418)
- Testing
- Education
- Where
- 70 sites in France, Germany and 4 more
- Volunteers
- 1,732 people
- Sponsor
- European Society of Cardiology
Malaria
A Cluster-randomised Trial of Interventions to Improve Antimalarial Prescribing With Malaria Tests
Background. Overdiagnosis of malaria is widespread in health facilities throughout Africa, a situation that is unsustainable given the relatively high cost of artemisinin combination therapy (ACTs) compared to older…
- Trial name
- TACT (NCT01292707)
- Testing
- Control, HW, HWC
- Where
- Tanzania
- Volunteers
- 1,152 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Breast Cancer
Impact of OncoDoc2 on Guideline Compliance in the Management of Breast Cancer
The objective of the study is to evaluate how the use of OncoDoc2, a computerized guideline-based decision support system, could improve the compliance of multidisciplinary staff meeting decisions with local clinical practice…
- Trial name
- OncoDoc2 (NCT00728442)
- Testing
- ONCODOC LOGICIEL
- Where
- France
- Volunteers
- 816 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Health Services Misuse, Physician's Practice Patterns
Primary Care Clinician Commitments to Choosing Wisely®
This pragmatic trial examines the uptake and effects of primary care clinician commitments to follow 3 Choosing Wisely® recommendations.
- Conditions
- Health Services Misuse, Physician's Practice Patterns, Guideline Adherence, Unnecessary Procedures
- Trial name
- NCT02247050
- Testing
- Commitment invitation
- Where
- 6 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Michigan
Irritable Bowel Syndrome
Treatment of IBS in Primary Health Care.
The purpose of this study is to retrospectively evaluate treatment strategies for IBS used within primary Health care in Örebro Region.
- Trial name
- NCT05144581
- Volunteers
- 3,000 people
- Sponsor
- Region Örebro County
Hypercholesterolemia
Rosuvastatin ORBITAL Germany
The primary objective of the study is to compare the effect of rosuvastatin therapy plus compliance initiatives and rosuvastatin therapy alone for 12 months (52 weeks) on long-term cumulative direct and indirect disease-related…
- Trial name
- NCT00379249
- Testing
- Rosuvastatin
- Volunteers
- 8,000 people
- Sponsor
- AstraZeneca
Healthy, 24-Hour Movement Guidelines
A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers
The goal of this clinical trial is to evaluate whether a home-based mHealth intervention can improve adherence to the 24-Hour Movement Guidelines in preschool-aged children (3-4 years old) who currently meet 0 or 1 of the…
- Conditions
- Healthy, 24-Hour Movement Guidelines, Feasibility Studies, Sleep
- Trial name
- Shining Star (NCT06667661)
- Testing
- Shining Star mHealth App
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Knee Osteoarthritis
Adherence to Treatment in Egyptian Patients With Knee Osteoarthritis
the aim is to measure the level of adherence of knee osteoartheritis patients to a Carefully curated program that follows the American College of Rheumatology/Arthritis (ACR) recommendation guidelines and investigate the factor…
- Trial name
- OA (NCT06064253)
- Testing
- health education
- Where
- Egypt
- Volunteers
- 154 people
- Sponsor
- Zagazig University
Valve Disease, Heart, Gender Bias
Valvular Heart Disease in Women Registry
Valvular heart disease (VHD) is a major global health issue. Untreated rheumatic heart disease persists in many regions, preventable with timely care.
- Conditions
- Valve Disease, Heart, Gender Bias, Guideline Adherence, Guideline Implementation
- Trial name
- VHD-W (NCT07196930)
- Where
- 2 sites in Egypt, Portugal
- Volunteers
- 800 people
- Sponsor
- Valvular Heart Disease in Women Registry
Cardiovascular Diseases, Renal Disease
OPTIMISation of Cardio-renal-metabolic-pulmonary Disease Guideline Adherence in High Risk Community Dwelling Individuals
Cardiovascular disease (CVD) causes a quarter of all deaths in the United Kingdom (UK). This is the single biggest area where the National Health Service (NHS) can save lives by detecting and treating risk factors early.
- Conditions
- Cardiovascular Diseases, Renal Disease, Metabolic Disease, Pulmonary Disease
- Trial name
- OPTIMISE (NCT06444711)
- Testing
- NICE guidance
- Where
- United Kingdom
- Volunteers
- 138 people
- Sponsor
- University of Leeds
Knowledge, Attitudes, Practice, Low Back Pain
Effect of an E-learning Intervention on Knowledge, Attitudes and Beliefs of Healthcare Professionals Managing Low Back Pain.
The purpose of the current research project is to examine if the healthcare professionals (HCPs) knowledge, attitudes, beliefs and behavior about the management of low back pain (LBP) patients changes following an e-learning…
- Conditions
- Knowledge, Attitudes, Practice, Low Back Pain, Physical Therapy, Physicians
- Trial name
- NCT05284669
- Testing
- Experimental e-learning, Traditional e-learning
- Where
- Belgium
- Volunteers
- 2,720 people, healthy volunteers welcome
- Sponsor
- Antoine Fourré
Diabetes, Dyslipidemia
Improving Adherence to Prescribing Guidelines for Cholesterol Lowering in Hospitalized Diabetic Patients
We hypothesize that when compared to usual care a greater proportion of hospitalized diabetic patients who are candidates for cholesterol lowering will be discharged with a prescription for a statin if their physicians are…
- Trial name
- NCT01113099
- Testing
- Academic detailing
- Where
- United States
- Volunteers
- 247 people
- Sponsor
- Washington University School of Medicine
COPD
Using Large Language Models Such As GPT-4 to Assess Guideline Adherence in Patients With Chronic Obstructive Pulmonary Disease
According to studies in the US and the Netherlands, 33-40% of patients with chronic conditions receive care that does not follow guideline recommendations. These findings have also been demonstrated in the management of COPD.
- Trial name
- IMPL-AI-MENT (NCT06410547)
- Testing
- LLM
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Charite University, Berlin, Germany
HFrEF - Heart Failure With Reduced Ejection Fraction, Guideline Adherence
Guideline Implementation and Quality of Care Evaluation in Patients With Heart Failure and Reduced Ejection Fraction (HFrEF)
The IMPLEMENT HF study is part of the national heart failure quality of care registry (evaluation of given health care). Within the HF registry, the investigators will investigate whether mirror information on the actual 4…
- Trial name
- IMPLEMENT HF (NCT07702760)
- Where
- Netherlands
- Volunteers
- 1,500 people
- Sponsor
- Jasper Brugts MD PhD