Clinical trials: Gynaecological Cancer
Major Gynecological Cancer Surgery, Low Flow Anesthesia
The Relationship Between Body Mass Index and Patient Outcomes in Low Flow Anaesthesia
This study was designed as a prospective observational study.
- Trial name
- NCT06636448
- Testing
- the effect of body mass index during low-flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Gynecologic Cancers, Postoperative Pain
Postoperative Chronic Pain in Gynaecological Cancer Surgery
The aim of this study was to determine the incidence of postoperative chronic pain in gynaecological cancer surgery and the analgesia methods used for postoperative analgesia.
- Trial name
- NCT07077889
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Duygu Akyol
Ovarian Cancer
Individualised Versus Conventional Medical Follow-up for Women After Primary Treatment for Ovarian Cancer.
The purpose of this study in women who have completed primary treatment for ovarian cancer is to investigate the effects of individualised follow-up care delivered by a nurse compared to conventional medical follow-up on quality…
- Trial name
- NCT02298855
- Testing
- Individualised follow-up
- Where
- 3 sites in United Kingdom
- Volunteers
- 113 people
- Sponsor
- University College, London
Gynaecological Oncology, Gynaecological Malignancies
Laparotomy vs Laparoscopy in Endometrial Cancer Staging
Endometrial cancer is one of the most common gynecological malignancies worldwide. Surgical staging is the cornerstone of management and traditionally performed via laparotomy.
- Conditions
- Gynaecological Oncology, Gynaecological Malignancies, Laparoscopic
- Trial name
- NCT07546825
- Testing
- laparoscopic surgical staging, open surgical staging
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Assiut University
Gynecological Cancers
Study to Assess the Safety and Effects of Porphysome Nanoparticles for Imaging in Gynaecological Cancers
This is an open-label, first-in-human, dose escalation study evaluating investigational drug PORPHYSOSMES (PS, pegylated porphyrin-lipid conjugate-containing nanoparticle suspension) and 64Cu-PORPHYSOMES (64Cu-PS, pegylated…
- Trial name
- NCT06977126
- Testing
- PORPHYSOMES, 64Cu-PORPHYSOMES
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University Health Network, Toronto
Gynecologic Cancer, Radiotherapy Side Effect
Bone Toxicity Following Pelvic Radiotherapy
A randomised controlled clinical feasibility trial to determine the feasibility and acceptability of a "musculoskeletal health package (MHP)" intervention in women undergoing pelvic radiotherapy for gynaecological malignancies…
- Conditions
- Gynecologic Cancer, Radiotherapy Side Effect, Fracture
- Trial name
- RadBone (NCT04555317)
- Testing
- Musculoskeletal health package
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- The Christie NHS Foundation Trust
Stroke, Spinal Cord Diseases
Use of tDCS Stimulation in Neurological and Gynaecological Conditions
The aim of the study is to test the effect of tDCS stimulation on upper and lower limb function in neurological patients and to reduce pain in gynaecological patients.
- Conditions
- Stroke, Spinal Cord Diseases, Nerve Root Disorder, Endometriosis
- Trial name
- tDCS (NCT06891690)
- Testing
- tDSC stimulation
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Ovarian Neoplasms, Breast Neoplasms
Establishment of a Tumor Bank for Blood Samples
Establishment of a tumor bank, consisting of blood samples of tumor patients and healthy people as controls. The blood samples will be collected systematically together with the corresponding clinical data.
- Conditions
- Ovarian Neoplasms, Breast Neoplasms, Colorectal Neoplasms, Neoplasms of the Female Genitalia
- Trial name
- NCT01763125
- Testing
- Blood collection
- Where
- 6 sites in Austria, Belgium and 2 more
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Gynecologic Cancers
Geriatric Patients Undergoing Gynaecological Cancer Surgery
Sınce old age includes variables such as genetics, chronic diseases, lifestyle, aging can be classified as chronological, social, physiological and psychological.
- Trial name
- NCT07077629
- Testing
- morbidity and mortality
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Myomas, Ovary Cysts
The Efficacy and Safety Study of a New Cross-linked Hyaluronan Hydrogel in the Reduction of Postsurgical Peritoneal Adhesions
The purpose of this study was to determine whether the new crosslinked hyaluronan hydrogel was safe to use, and was effective for the prevention/reduction of adhesion formation following gynecological surgery
- Conditions
- Myomas, Ovary Cysts, Endometriotic Cysts, Adhesions
- Trial name
- BAP (NCT02166554)
- Testing
- Saline, Cross-linked Hyaluronan Hydrogel
- Where
- 7 sites in China
- Volunteers
- 216 people
- Sponsor
- BioRegen Biomedical (Changzhou) Co., Ltd
Survivorship, Breast Cancer
Accessible Cancer Care to Enable Support for Survivors Programme
In Singapore, cancer patients are not consistently assessed for unmet survivorship care needs and systematically identified for subsequent referral to useful care services.
- Conditions
- Survivorship, Breast Cancer, Gynecologic Cancer
- Trial name
- ACCESS (NCT04014309)
- Testing
- Supportive and survivorship care program, Usual care
- Where
- Singapore
- Volunteers
- 226 people
- Sponsor
- National University of Singapore
Lynch Syndrome
Protocol for Non-invasive Gynaecological Surveillance in Lynch Syndrome
Lynch syndrome is the most common inherited condition that raises a person's risk of getting certain cancers. It happens because of changes in genes that normally fix damaged DNA.
- Trial name
- PREDI-ENDO (NCT07877779)
- Where
- United Kingdom
- Volunteers
- 1,450 people
- Sponsor
- University of Edinburgh
Cervix Cancer, Endometrium Cancer
Probe-based and Needle-based Confocal Laser Endomicroscopy During Gynaecological Procedures.
The protocol aims at demonstrating the technical feasibility and safety of doing endomicroscopic imaging (both probe-based confocal laser endomicroscopy (pCLE) and needle-based confocal laser endomicroscopy, nCLE) during…
- Conditions
- Cervix Cancer, Endometrium Cancer, Ovarian Cancer, Carcinoma in Situ of Fallopian Tube
- Trial name
- NCT02221076
- Testing
- Confocal Laser Endomicroscopy (CLE)
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Mauna Kea Technologies
Clear Cell Tumor, Gynecologic Cancer
A Study of Pembrolizumab in Patients With Advanced Gynaecological Clear Cell Cancer
PEACOCC is a multi-centre, single arm, single stage phase II trial. The overall aim is to determine whether treatment with pembrolizumab is effective in patients with advanced clear cell gynaecological cancer.
- Conditions
- Clear Cell Tumor, Gynecologic Cancer, Advanced Cancer
- Trial name
- PEACOCC (NCT03425565)
- Testing
- Pembrolizumab
- Where
- 5 sites in United Kingdom
- Volunteers
- 48 people
- Sponsor
- University College, London
Ovarian Neoplasm Epithelial
The Effects of Hemodilution Methods in Patients Undergoing Primary Debulking Gynaecological Surgery
Primary cytoreductive surgery for ovarian cancer is an ideal setting to evaluate endothelial function under ANH and AHH, as the procedure is associated with moderately high blood loss.
- Trial name
- NCT06103214
- Testing
- acute normovolemic hemodilution (ANH), acute hypervolemic hemodilution (AHH)
- Volunteers
- 144 people
- Sponsor
- Zhejiang Cancer Hospital
Gynaecological, Urological or Rectal Cancer, Chemotherapy-Induced Peripheral Neuropathy
The Use of Acupuncture to Reduce Chemotherapy Induced Peripheral Neuropathy in Gynaecological Cancer Patients
Objectives: To explore the feasibility and effectiveness of acupuncture on reducing Chemotherapy Induced Peripheral Neuropathy (CIPN) in gynaecological cancer patients who have received carboplatin and paclitaxel chemotherapy…
- Conditions
- Gynaecological, Urological or Rectal Cancer, Chemotherapy-Induced Peripheral Neuropathy, Acupuncture
- Trial name
- AcuCIN (NCT06769061)
- Testing
- Acupuncture
- Where
- Hong Kong
- Volunteers
- 75 people
- Sponsor
- Karen Kar Loen CHAN
Gynaecological Cancers
Vaginal Fluid Derived Biomarkers in the Early Detection and Evolution of Gynaecological Cancers
This study will investigate vaginal secretions in those patients with cancer versus those who are cancer free and compare changes in specific markers that change when a cancer first develops.
- Trial name
- VIOLET (NCT07622953)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Female Genital Diseases, Ovarian Cancer
Prospective Evaluation of Lymphoedema Among Patients With Gynaecological Cancer
This project will conduct a prospective, longitudinal, observational cohort study to assess the onset and incidence of lymphoedema, as well as investigate factors associated with its development among women newly diagnosed with…
- Conditions
- Female Genital Diseases, Ovarian Cancer, Cervical Cancer, Endometrial Cancer
- Trial name
- LEGS (NCT00604994)
- Where
- 6 sites in Australia
- Volunteers
- 761 people
- Sponsor
- Queensland Centre for Gynaecological Cancer
Cervix Cancer, Endometrial Cancer
Opioid Free Anaesthesia in Oncologic Gynaecological Surgery: Is There Any Benefit?
Opioid Free Anesthesia (OFA) is a multimodal anesthesia and emerging technique that spares the use of opioids and involve other adjuvant anesthetics, which have demonstrated in vitro influence on immunologic and inflammatory…
- Conditions
- Cervix Cancer, Endometrial Cancer, Ovarian Cancer, Breast Cancer
- Trial name
- NCT05448586
- Testing
- Opioid
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Malignant Female Reproductive System Neoplasm, Follow-up
Person-centred Support for Women After Treatment for Gynaecological Cancer
Women treated for gynaecological cancer perceive many difficulties in life on the personal, social, and physical levels. Today they are offered a 3 to 5 year follow-up programme at the hospital where the main purpose is to…
- Conditions
- Malignant Female Reproductive System Neoplasm, Follow-up, Supportive Care, Psychosocial Circumstances
- Trial name
- PESU (NCT01784406)
- Testing
- Autonomy supportive counselling
- Where
- Denmark
- Volunteers
- 165 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet