Clinical trials: Gynecologic Disorders
Cancer, Thoracic Cancer
Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT
Cancer-related fatigue (CRF) is a significant problem for cancer patients. This prospective, basic science, observational study will evaluate for changes in CRF associated with molecular characteristics prior to, during, and at…
- Conditions
- Cancer, Thoracic Cancer, Gynecologic Cancer, Head and Neck Cancer
- Trial name
- NCT06633224
- Testing
- Blood Specimen Collection, Stool Specimen Collection, Quality of Life (QOL) Questionnaires
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of California, San Francisco
Hysterectomy, Genital Diseases, Female
Follow-up Strategies for Improved Postoperative Recovery After Benign Hysterectomy
The purpose of the study is to investigate the effect of four different follow-up strategies on postoperative recovery following vaginal or abdominal hysterectomy for benign conditions.
- Conditions
- Hysterectomy, Genital Diseases, Female, Pain
- Trial name
- POSTHYSTREC (NCT01526668)
- Testing
- Follow-up strategy, No contact after discharge
- Where
- 5 sites in Sweden
- Volunteers
- 525 people
- Sponsor
- University Hospital, Linkoeping
Cardiac Disorder, Hepatic Disorder
Kosmos Anatomical Object Labeling and View Identification Pivotal Study
This is a multi-site, multi-group study that obtained two sets of ultrasound scans from all enrolled participants. Participants underwent limited ultrasound scanning by both cardiac sonographers and abdominal sonographers.
- Conditions
- Cardiac Disorder, Hepatic Disorder, Spleen Disorder, Kidney Disorder
- Trial name
- NCT06468787
- Testing
- Kosmos Anatomical Object Labeling and View Identification Algorithms
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- EchoNous Inc.
Postoperative Complications, Obesity
Negative Pressure Wound Therapy in Obese Gynecologic Oncology Patients
The purpose of the study is to test whether the use of a new wound closure technique can decrease the rates of wound complications in obese cancer patients.
- Conditions
- Postoperative Complications, Obesity, Gynecologic Neoplasms
- Trial name
- NCT02309944
- Testing
- Standard Wound Closure, Prevena™ Incision Management System
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Breast Cancer, Gynecologic Cancer
Management of Perioperative Anxiety by the Cardiac Coherence Technique Coupled With a Hypnosis Session
the investigator proposes to use the cardiac coherence technique coupled with a hypnosis session to improve post-operative recovery.
- Trial name
- COHEC (NCT03981731)
- Testing
- Cardiac coherence
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Atelectasis, Compliance, Patient
Restoration of Pulmonary Compliance After Laparoscopic Gynaecologic Surgery Using a Recruitment Maneuver
To investigate the hypothesis that an alveolar recruitment maneuver after the release of pneumoperitoneum would restore the lung compliance to the baseline values after a laparoscopic gynaecologic surgery.
- Trial name
- NCT06203665
- Testing
- Recruitment Maneuver
- Where
- Greece
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Panagiota Griva
Fallopian Tube Cancer, Peritoneal Neoplasms
Predictors of Relapse of Ovarian, Peritoneal, and Fallopian Tube Cancers
This study will develop a blood test that can be used to predict a relapse of ovarian, peritoneal, or fallopian tube cancer. The type of testing is called proteomics, or the study of proteins in living cells.
- Conditions
- Fallopian Tube Cancer, Peritoneal Neoplasms, Epithelial Ovarian Cancer
- Trial name
- NCT00086567
- Where
- 11 sites in United States
- Volunteers
- 119 people
- Sponsor
- National Cancer Institute (NCI)
Ovarian Cancer
Data and Specimen Bank of Patients Diagnosed With, and at High-risk for, Gynecologic Cancers
The purpose of this project is to establish a bank at UVa of tampon samples, cervical swabs, blood, associated tumor specimens that would otherwise be discarded, and relevant medical data from consenting patients that have…
- Trial name
- NCT04170712
- Testing
- Tampons
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Ovarian Cysts
Intraperitoneal Ropivacaine Nebulization for Pain Control After Gynecologic Laparoscopic Surgery
The purpose of this study is to assess if intraperitoneal nebulization of Ropivacaine 150 mg may prevent the use of morphine during the first day after laparoscopic ovarian cyst surgery.
- Trial name
- NCT01142622
- Testing
- Ropivacaine nebulization, Ropivacaine instillation
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- San Gerardo Hospital
Gynecologic Cancer, Anemia, Iron Deficiency
Ferric Derisomaltose/Iron Isomaltoside and Outcomes in the Recovery of Gynecologic Oncology ERAS
Iron deficiency has been reported in up to 35% of patients with a gynecologic malignancy. These patients often require surgical intervention to determine the stage and to treat their illness.
- Conditions
- Gynecologic Cancer, Anemia, Iron Deficiency, Surgery
- Trial name
- FORGE (NCT05467319)
- Testing
- Ferric Derisomaltose Injection, Normal saline
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary
Gynecologic Cancer, Pelvic Floor Disorders
Pelvic Floor Dysfunction and Aerobic Training in Gynecological Cancer
The incidence of gynecological cancer and the related death rates in the world are increasing every year. Unfortunately, pelvic floor disorders (PFDs) such as pelvic pain, dyspareunia, vaginal stenosis, and urinary incontinence…
- Conditions
- Gynecologic Cancer, Pelvic Floor Disorders, Aerobic Exercise
- Trial name
- NCT06406322
- Testing
- PFMT, Aerobic Exercise
- Volunteers
- 40 people
- Sponsor
- Atılım University
Gynecologic Cancer
Cross-sectional and Questionnaire Study for Leg Lymphedema
The purpose of this study is to identify the incidence,feature,clinical significance for leg lymphedema after gynecologic cancer treatment.
- Trial name
- NCT02069171
- Volunteers
- 333 people
- Sponsor
- National Cancer Center, Korea
Sexual Dysfunction, Pelvic Floor Disorders
Improving Women's Function After Pelvic Radiation
The purpose of the study is to develop and test an intervention combining physical therapy (PT) and coping skills training to improve women's sexual function after pelvic radiation.
- Conditions
- Sexual Dysfunction, Pelvic Floor Disorders, Gynecologic Cancer
- Trial name
- NCT04544735
- Testing
- Integrated Physical Therapy and Coping Skills Training
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Duke University
Post Operative Analgesia, Opioid Consumption, Postoperative
Intravenous Acetaminophen to Reduce Post-operative Opioid Consumption
Acetaminophen (Tylenol) is a commonly used medication after surgery to control pain. Tablets for oral use and suppositories for rectal use are the most frequently employed forms of acetaminophen after surgery.
- Conditions
- Post Operative Analgesia, Opioid Consumption, Postoperative, Acetaminophen, Abdominal Surgeries
- Trial name
- ACETAPOP (NCT06923540)
- Testing
- IV Acetaminophen
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Breast Cancer, Solid Tumors, Adult
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
Study STX-478-101 (LY4064809) is a multipart, open-label, phase 1/2 study evaluating the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of STX-478 (LY4064809) in participants with advanced solid…
- Trial name
- PIKALO-1 (NCT05768139)
- Testing
- STX-478, Fulvestrant, Ribociclib
- Where
- 65 sites in United States, Belgium and 7 more
- Volunteers
- 880 people
- Sponsor
- Eli Lilly and Company
Advanced Digestive Cancer, Advanced Gynecologic Cancer
Identification of Innovative Biomarkers Related to the Immune System or Tumor Microenvironment to Promote the Efficacy of Immunotherapies
The immune system may be involved in the recognition and destruction of tumor cells or cells undergoing transformation. It is also currently accepted that the quality of immune responses can influence the evolution of cancers…
- Trial name
- HORIZON (NCT06626269)
- Testing
- Blood sample, Tumor tissue
- Where
- 2 sites in France
- Volunteers
- 700 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Breast Cancer, Gynecologic Cancer
Clinical Investigation of the Effects of Semiconductor Embedded Therapeutic Garments on Cancer-related Cognitive Impairment in Breast and Gynecological Cancer Patients
The purpose of this study is to assess the feasibility of a wearing semiconductor embedded headband for cancer-related cognitive impairment in patients with breast or gynecological cancers.
- Conditions
- Breast Cancer, Gynecologic Cancer, Cancer-related Cognitive Difficulties
- Trial name
- HEADBAND (NCT07173101)
- Testing
- Semiconductor embedded headband
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Utah
Cervical Cancer, Endometrial Cancer
PET-CT vs. Integrated MR-PET Scanning of GYN Cancers
This research study is an imaging pilot study. Imaging pilot studies explore the potential benefit of one imaging approach compared to another clinically accepted approach.
- Conditions
- Cervical Cancer, Endometrial Cancer, Ovarian Cancer
- Trial name
- NCT01779128
- Testing
- PET-CT, MR-PET
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Pain
Study of TAP and Laparoscopic and Robotic Gynecologic Procedures and Obese Women
Study the effect of the Transversis Abdominis Plane (TAP) block on pain after surgery for obese women undergoing laparoscopic or robotic gynecologic procedures.
- Trial name
- NCT01866917
- Testing
- Ropivacaine 0.5% 20cc injectate bilaterally
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Ovary Cancer, Endometrial Cancer
Multimedia Aid for Genetic Testing in Gynecologic Oncology
This pilot study aims to estimate rates of genetic testing in patients with ovarian and endometrial cancer before and after the implementation of educational videos about genetic testing.
- Trial name
- NCT07084168
- Testing
- Educational videos, Survey
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center