Clinical trials: Gynecologic Laparoscopic Surgery
Surgery, Gynecologic Disease
Study Evaluating the Success Rate of Outpatient Management of the Total Benign Hysterectomy by Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Compared to Each of the Two Laparoscopic Routes (Conventional and Robot-assisted).
Benign total hysterectomy is one of the most commonly performed gynecological surgery. Conventionally performed by a classical surgical approach, it is now provided routinely and for several years by laparoscopy and more recently…
- Trial name
- HYSTERAMBU (NCT06471049)
- Testing
- Benign Hysterectomy
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Elsan
Gynecologic Surgery
Low Versus Standard Pressure Pneumoperitoneum
The role of laparoscopy in gynecological and gyne-oncological surgery has dramatically increased over the past decades. Although laparoscopic procedure has several advantages over open surgery such as reduced blood loss, faster…
- Trial name
- NCT04947982
- Testing
- carbon dioxide
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Pain, Postoperative
Fascial Closure Technique After Gynecologic Laparoscopic Surgery and Postoperative Pain
Our study aims to determine postoperative pain outcomes when comparing port site > 10 mm fascial closure with traditional direct closure versus use of laparoscopic fascial closure device in patients undergoing minimally invasive…
- Trial name
- NCT04765306
- Testing
- Traditional Direct Fascial Closure, Fascial Closure Device
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Jessica G Putman
Postoperative Nausea and Vomiting
Dextrose Containing Fluid and the Postoperative Nausea and Vomiting in the Gynecologic Laparoscopic Surgery
The investigators tested the hypothesis that administration of intravenous dextrose as a maintenance fluid in gynecologic laparoscopic surgery would reduce the incidence and severity of postoperative nausea and vomiting (PONV)…
- Trial name
- NCT03139383
- Testing
- dextrose solution, saline solution
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Reperfusion Injury
Pulmonary Protection of Transcutaneous Electrical Acupoint Stimulation in Gynecologic Laparoscopic Surgery
TEAS might protect against postoperative pulmonary such as ischemia-reperfusion injury (IRI) and atelectasis. We tested the hypothesis that transcutaneous electrical acupoint stimulation protects against postoperative pulmonary…
- Trial name
- NCT02850471
- Testing
- electroacupuncture
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Pain, Post-operative, Pneumoperitoneum
Does Trendelenburg Positioning During Pulmonary Recruitment Breaths Affect Post-laparoscopy Shoulder Pain
The goal of this clinical trial is to evaluate whether different positioning in the operating room during removal of laparoscopic surgical gas differs in post-surgery shoulder pain.
- Conditions
- Pain, Post-operative, Pneumoperitoneum, Urogynecologic Surgery
- Trial name
- NCT07631728
- Testing
- Pulmonary recruitment maneuver, Trendelenburg position
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankita Gupta
Atelectasis, Compliance, Patient
Restoration of Pulmonary Compliance After Laparoscopic Gynaecologic Surgery Using a Recruitment Maneuver
To investigate the hypothesis that an alveolar recruitment maneuver after the release of pneumoperitoneum would restore the lung compliance to the baseline values after a laparoscopic gynaecologic surgery.
- Trial name
- NCT06203665
- Testing
- Recruitment Maneuver
- Where
- Greece
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Panagiota Griva
Gynecologic Laparoscopic Surgery
Intrathecal Mg in Gynecologic Laparoscopic Surgeries.
The investigators aim to investigate the differences between intrathecal Bupivacaine + Mg sulfate in spinal anesthesia versus Bupivacaine on surgeon satisfaction and postoperative pain in gynecologic laparoscopic surgeries.
- Trial name
- NCT02671227
- Testing
- intrathecal Mg sulfate., intrathecal bupivacaine 15 mg.
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pelvic Pain, Endometriosis
Postoperative Narcotic Use After Laparoscopic Gynecologic Surgery
This will be a prospective, randomized, double blinded placebo-controlled study at Erlanger hospital. Eligible patients who provide consent will be randomized into one of two arms receiving continuous intra-peritoneal local…
- Conditions
- Pelvic Pain, Endometriosis, Pelvic Prolapse
- Trial name
- NCT04118777
- Testing
- Ropivacaine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Tennessee, Chattanooga
Gynecologic Laparoscopic Surgery, Minimally Invasive Surgical Procedures
Impact of a Preoperative Instructional Video on Patient Preparedness
In this study, the investigators will evaluate the impact of a pre-operative instructional video for patients undergoing minimally invasive gynecologic surgery.
- Trial name
- NCT07364968
- Testing
- Study group of patients will receive standard of care
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of California, Riverside
Postoperative Pain, Shoulder Pain
Bupivacaine With Epinephrine Over Diaphragm in Laparoscopy
Postoperative shoulder pain is often reported to be particularly bothersome after laparoscopy. The benefits of local anesthetic, such as bupivacaine, applied to subcutaneous tissue for general postoperative pain management after…
- Trial name
- NCT07400146
- Testing
- Instillation of Bupivacaine with epinephrine over the diaphragm
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Pelvic Organ Prolapse, Abnormal Uterine Bleeding
Evaluating Artisential Laparoscopic Instruments in Gynecologic Surgery
This study evaluates the efficacy and safety of Artisential laparoscopic instruments in minimally invasive gynecologic surgery.
- Conditions
- Pelvic Organ Prolapse, Abnormal Uterine Bleeding, Mesh Augmentation, Laparoscopic Surgery
- Trial name
- MIGS-ART (NCT06050161)
- Testing
- Articulating laparoscopic instrument, Conventional laparoscopic instrument, Robotic surgical instrument
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kern Medical Center
Infertility Female, Hemodynamic Instability
Lidocaine vs Magnesium Sulfate for Hemodynamic Stability During Emergence in Infertility-Related Laparoscopic Surgery"
This study is being conducted to compare two medications, intravenous lidocaine and intravenous magnesium sulfate, and their ability to keep blood pressure and heart rate stable during the period of waking up from general…
- Trial name
- LidoMagGyna (NCT07359560)
- Testing
- Lidocaine (drug), Normal Saline (Intravenous), magnesium sulfate
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Tissue Adhesions
A Randomized Multi-centre Study to Assess the Safety and Manageability of a Laparoscopic Adhesion Barrier in Women Undergoing Gynecologic Laparoscopic Surgery Followed by Second Look Laparoscopy
The purpose of this study is to obtain data on the safety and manageability of applying LABS™ to the uterus and other areas of surgical trauma in the pelvis and abdomen following laparoscopic gynaecologic surgery.
- Trial name
- LABS-1 (NCT02260115)
- Testing
- LABS™, Surgical Control
- Where
- 4 sites in Germany, Greece
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Actamax Surgical Materials LLC
Post Operative Pain, Acute
Effect of Preoperative Oral Pregabalin Versus Intraoperative Fentanyl on Postoperative Analgesia
Pregabalin is a structural analogue of gamma amino butyric acid (GABA). It binds to presynaptic alpha-2-delta subunit of voltage gated calcium channels in the brain and the spinal cord.
- Trial name
- NCT05150795
- Testing
- Pregabalin 150mg, Fentanyl 100 micrograms ampoule
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
the Efficacy of Analgesia of Laparoscopic TAP Block in Minimally Invasive Gynecology Surgeries
Efficacy of Laparoscopic-assisted Transversus Abdominus Plane (TAP) Block Compared to Ultrasound-guided TAP Block in Minimally Invasive Gynecologic Surgeries: A Prospective, Randomized Control Trial.
We propose a clinical trial to determine the efficacy of Laparoscopic Transversus Abdominis Plane (LA-TAP) performed intraoperatively compared with usual postoperative analgesia without LA-TAP block.
- Trial name
- TAP (NCT04345341)
- Testing
- TAP block with liposomal bupivacaine and bupivacaine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
Postoperative Ileus
Coffee Consumption for Intestinal Function Recovery After Laparoscopic Gynecologic Surgery
Minimally invasive surgery (MIS) has revolutionized women's healthcare. Laparoscopy is an excellent route of MIS. Today, laparoscopic surgery is one of the major procedure in the management of a gynecologic disease.
- Trial name
- NCT03963180
- Testing
- coffee
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Minimally Invasive Surgical Procedure, Hysterectomy
The Impact of Post-operative Voiding Trial on Length of Stay Following Laparoscopic Hysterectomy: A Prospective, Randomized Control Trial
The aim of this study is to investigate the impact of an active voiding trial compared to a passive voiding trial on time to discharge following a planned same day discharge laparoscopic hysterectomy.
- Conditions
- Minimally Invasive Surgical Procedure, Hysterectomy, Urinary Retention
- Trial name
- NCT04487600
- Testing
- Active voiding trial
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Gynecologic Disease
Traditional Versus Virtual Reality for Surgical Skills for ObGyn Residents
This study will verify if a comprehensive laparoscopic curriculum using virtual reality demonstrates skills transfer to the operating room, compared to the traditional teaching method.
- Trial name
- SIMUTEC (NCT03395821)
- Testing
- Conventional training, Virtual Reality+conventional training
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Gynecologic Surgical Procedures, Gastric Injury
Surgeon Perception of Gastric Decompression at Time of Gynecologic Laparoscopy
The goal of this clinical trial is to test whether it is necessary to decompress the stomach during gynecologic laparoscopy. The main questions it aims to answer are: Is there appropriate visualization during surgery without…
- Conditions
- Gynecologic Surgical Procedures, Gastric Injury, Aspiration, Nausea, Postoperative
- Trial name
- NCT06137976
- Testing
- Gastric decompression (oropharyngeal or nasopharyngeal gastric tube)
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Northwestern University