Clinical trials: Gynecological Surgeries
Gynecological; Surgery (Previous), Affecting Fetus, Postoperative Pain
Mü-opioid Receptor Level and Postoperative Pain in Patients With Gynecological Laparoscopy
The hypothesis that gonadal hormones may affect the perception of pain is an interesting research area. This prospective observational study will undergo elective laparoscopic gynecological surgery to 18-65 years, is planned to…
- Trial name
- NCT04690491
- Testing
- follicular cyclus, luteal cyclus
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bozok University
Neoplasms
A Randomized Controlled Trial of a Robotic Simulation Curriculum to Teach Robotic Suturing
The aim of this study is to determine if training with a robotic simulator improves ability to perform robotic suturing. We aim to recruit 38 participants (attending surgeons or residents in obstetrics and gynecology, urology…
- Trial name
- NCT01811095
- Testing
- Training
- Where
- 2 sites in Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- McGill University
Laparoscopic Hysterectomy
Surgicel Snow in Gynecological Surgery
Surgicel Snow is an FDA approved topical hemostatic agent for use during surgical procedures. Like the other mechanical agents, Surgicel Snow forms a physical barrier that blocks blood flow while providing a large surface area…
- Trial name
- NCT02908841
- Testing
- Surgicel Snow, Standard of Care
- Where
- 3 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Danbury Hospital
Malignant Female Reproductive System Neoplasm
Physiatry-Led Cancer Prehabilitation During Neoadjuvant Systemic Therapy to Improve Function in Stage III-IVA Gynecologic Cancer Patients
This clinical trial studies whether physiatry-led cancer prehabilitation can be used during systemic treatment before surgery (neoadjuvant systemic treatment [NST]) to improve function in stage III-IVA gynecologic cancer…
- Trial name
- NCT07608445
- Testing
- Educational Intervention, Goal Setting, Interview
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Transversalis Fascia Plane Block, Gynecologic Surgical Procedures
Efficacy of US-guided TFPB in Open Gynecologic Surgery
Transversalis fascia plane block (TFPB) has been studied and has shown to be very effective in controlling postoperative pain after caesarean section but has not been studied in open gynecologic surgery with transverse incision.
- Trial name
- NCT06847022
- Testing
- US-guided transversalis fascia plane block
- Where
- Thailand
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Magnesium Sulfate, Thromboelastometry
Magnesium Sulfate and Postoperative Hypercoagulability in Laparoscopic Gynecological Surgeries
This will be a prospective randomized, double-blind study, aiming at investigating the effects of magnesium sulfate on postoperative hypercoagulability in patients undergoing laparoscopic gynecological surgeries under general…
- Trial name
- NCT06717490
- Testing
- Magnesium sulphate
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marianna Mavromati
Gynecological Disorder
Timing of Rocuronium After Induction With Propofol on Temporal Summation of Pain
Temporal summation of pain, which is defined as the perception of increasingly greater pain evoked by repetitive painful stimuli, is highly variable between individuals.
- Trial name
- NCT04547608
- Testing
- The difference of the timing of rocuronium administration after propofol injection
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Gynecologic Cancer, Surgical Procedure, Unspecified
Laparoscopic Ultrasound Examination: Analysis of Feasibility
This is a prospective cohort study to assess the feasibility of the laparoscopic ultrasound examination, directly by surgeons, during minimally invasive gynaecological surgery.
- Trial name
- LUXA (NCT06278636)
- Testing
- Laparoscopi ultrasound examination
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Morbid Obesity
Two Different Regimens of Bemiparin as a Thromboprophylaxis in Morbidly Obese Surgical Patients
Morbid obesity, is known to be associated with a high risk of VTE and, unfortunately, fixed doses of anticoagulant regimens may not provide optimal VTE prophylaxis in these patients especially after surgery.
- Trial name
- NCT05569681
- Testing
- Bemiparin 3500, Bemiparin 5000 IU
- Where
- Iraq
- Volunteers
- 1,248 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Hysterectomy, Gynecologic Surgical Procedures
Intraperitoneal Infusion of Analgesic for Postoperative Pain Management
The study is a prospective, double-blinded, placebo-controlled multi-center trial to measure if postoperative pain and the amount of narcotics used are reduced by a clinically significant amount in women undergoing minimally…
- Conditions
- Hysterectomy, Gynecologic Surgical Procedures, Narcotic Use, Pain, Postoperative
- Trial name
- ON-Q (NCT04130464)
- Testing
- Ropivacaine Infusion from ON-Q Pump, Ropivacaine + Ketorolac Infusion from ON-Q Pump, Normal Saline Infusion from ON-Q Pump
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ying Liu
General Anesthesia
Impact of Virtual Reality (VR) and Music Intervention
The purpose of this study is as follows.The purpose of this study is as follows. First, it aims to examine the differences in anxiety, depression, and sleep quality based on the inclusion of a music intervention during relaxation…
- Trial name
- NCT06728163
- Testing
- written education group, VR educational material + breathing relaxation with verbal instruction, VR educational material + breathing relaxation with music intervention
- Where
- South Korea
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Prevention
Intravenous Versus Intraperitoneal Instillation of Ondansetron for Decreasing Incidence of Nausea and Vomiting After Laparoscopic Gynecological Surgeries.
Study the effect of intraperitoneal instillation vs intravenous ondansetron on PONV added to intraperitoneal bupivacaine for enhanced recovery and to decrease incidence of PONV after laparoscopic surgeries.
- Trial name
- NCT05317611
- Testing
- Intraperitoneal instillation of ondansetron and bupivacaine, Intravenous ondansetron and intraperitoneal instillation of bupivacaine, Intraperitoneal instillation of bupivacaine
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Infertility Female, Hemodynamic Instability
Lidocaine vs Magnesium Sulfate for Hemodynamic Stability During Emergence in Infertility-Related Laparoscopic Surgery"
This study is being conducted to compare two medications, intravenous lidocaine and intravenous magnesium sulfate, and their ability to keep blood pressure and heart rate stable during the period of waking up from general…
- Trial name
- LidoMagGyna (NCT07359560)
- Testing
- Lidocaine (drug), Normal Saline (Intravenous), magnesium sulfate
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Pain Score
Comparison of Efficacy of Bupivacaine for Relief Postoperative Pain in Women Undergoing Laparoscopic Gynecologic Surgery
To comparison of efficacy of Bupivacaine for relief postoperative pain in women undergoing laparoscopic gynecologic surgery
- Trial name
- NCT03259243
- Testing
- Bupivacaine Hydrochloride
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Pain, Postoperative
Efficacy of Transversus Abdominis Plane Block Versus Local Injection of Pain Medication
The purpose of this study is to determine if there is a better method of administering pain medication prior to minimally invasive gynecological surgery so that postoperative pain and/or narcotic usage may be minimized.
- Trial name
- NCT02314104
- Testing
- ropivacaine
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Liberman, Eric, D.O.
Anxiety, Postoperative Pain
Sublingual Melatonin for Anxiety and Pain in Elective Gynecologic Surgery
This prospective randomized controlled study aims to evaluate the anxiolytic effect of preoperative sublingual melatonin and its impact on postoperative pain scores when administered in two different doses to female patients…
- Conditions
- Anxiety, Postoperative Pain, Anesthesia
- Trial name
- NCT06997263
- Testing
- Melatonin 3 mg Sublingual, Melatonin 6 mg Sublingual
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Benha University
Obesity, Incision, Surgical
Laparoscopic Incision Closure s in Obese Patients
Several methods for closure of trocar wounds are known in laparoscopic surgery including mostly transcutaneous or subcuticular suture or adhesive paper tape.
- Trial name
- LICOP (NCT05622110)
- Testing
- Adhesive glue closure, Subcuticular closure
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pain, Pneumoperitoneum
Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology
This study seeks to evaluate post-operative patient pain and quality of life, and intra-operative hemodynamic status and changes in inflammatory markers, with use of a pressure-barrier insufflator and conventional insufflator at…
- Conditions
- Pain, Pneumoperitoneum, Inflammation, Quality of Life
- Trial name
- NCT02853591
- Testing
- Pneumoinsufflator mode and setting
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
C.Delivery; Surgery (Previous), Gynecological, Inappropriate Device Stimulation of Tissue
The Effect of TEAS on the Quality of Early Recovery
During the past four decades, gynecologic laparoscopy has evolved from a limited method to an advanced operative approach that frequently serves as a substitute for laparotomy.
- Conditions
- C.Delivery; Surgery (Previous), Gynecological, Inappropriate Device Stimulation of Tissue, Delayed Emergence From Anesthesia
- Trial name
- NCT02619578
- Testing
- TEAS, Con, propofol, remifentanil, vecuronium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guizhou Provincial People's Hospital
Surgery
Ambulatory Gynecologic Surgery: Finding the Optimal Opioid Prescription
Currently there is a nationwide epidemic in opioid abuse and overdose deaths. While the opioid epidemic is multi-factorial one major source of excess opioids may be over-prescribing in the post-operative period.
- Trial name
- NCT03588910
- Testing
- Acetaminophen, Ibuprofen 600 mg, Oxycodone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center