Clinical trials: HDL
SARS-CoV Infection
HDL Target of CoViD19 ? Analysis on the Caregivers of the Reunion University Hospital
Since December 2019, the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) pandemic has spread around the world. The people most exposed to this virus remain the healthcare personnel who are on the front line in the…
- Trial name
- H-Cov-Run (NCT04384705)
- Testing
- research specific blood sample
- Where
- 2 sites in France
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Cardiovascular Diseases
Effect of the Antioxidant Micronutrients of Rapeseed Oil on the Prevention of Cardiovascular Diseases (Optim'Oils)
The purpose of this study is to assess the effect of optimized oil (enriched with micronutriments) on the prevention on cardiovascular diseases.
- Trial name
- NCT00852735
- Testing
- Rapeseed Oil (prevention of cardiovascular diseases)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Cardiovascular Diseases
The Effects of Fat and Theobromine on apoA-I
Rationale: Despite successful efforts to lower atherogenic serum low-density lipoprotein (LDL) cholesterol concentrations, a substantial residual cardiovascular risk is still present.
- Trial name
- NCT02085109
- Testing
- Fat milkshake, Theobromine
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cardiovascular Diseases
A Multicenter Pilot Study to Evaluate the Effect of EVOO on Lipid Parameters
The purpose of this multi-center, double-blinded pilot study is to determine if extra virgin olive oil (EVOO) has a positive effect on HDL cholesterol levels and anti-inflammatory markers for subjects diagnosed with…
- Trial name
- EVOO (NCT04760093)
- Testing
- Low polyphenol concentration extra virgin olive oil (EVOO), High polyphenol concentration extra virgin olive oil (EVOO)
- Where
- 3 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Ralph Hamill
Lipoproteins, Inflammatory Response
Investigating Age-dependent Effects of Egg Intake on HDL and Immune Profiles
The goal of this intervention study is to determine whether consumption of different fractions of chicken eggs, including egg whites, egg yolks, and whole eggs, confer different changes in markers of HDL function and T cell…
- Trial name
- NCT06086795
- Testing
- Whole eggs, Egg yolks, Egg whites
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Dyslipidemias, Hyperglycemia
Role of Ajwa Derived Polyphenols in Dyslipidaemias
World Health Organization report notifies of the escalating global burden of cardiovascular diseases (CVD), projecting that it will become the major worldwide cause of death and disability by 2020.
- Conditions
- Dyslipidemias, Hyperglycemia, Liver Dysfunction, Oxidative Stress
- Trial name
- NCT03805139
- Testing
- Ajwa Date (phoenix dactylifera)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Schizophrenia, Schizoaffective Disorder
The Antiatherogenic Properties of HDL in Psychiatric Patients With and Without Antipsychotic Therapy
Background: Among individuals with schizophrenia, there is an increased prevalence of obesity, dyslipidemia ,diabetes mellitus and related conditions such as cardiovascular disease.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- NCT01215383
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Weight Change, BMI
Childhood Obesity Prevention Project in Gran Canaria
Given the alarming rates of obesity and overweight in our child population, the investigators have developed an intervention strategy, based on a multidisciplinary, school-centered approach, which addresses nutritional education…
- Conditions
- Weight Change, BMI, Activity Level, Cholesterol (total and HDL)
- Trial name
- POI (NCT06607159)
- Testing
- Implementation of healthy habits teaching protocol
- Where
- Spain
- Volunteers
- 557 people, healthy volunteers welcome
- Sponsor
- Complejo Hospitalario Universitario Insular Materno Infantil
Hypercholesterolemia
Multiple Ascending Dose Study of SPC4955 in Healthy Subjects
The purpose of this study is to study safety and tolerability of SPC4955 in healthy subjects.
- Trial name
- NCT01365663
- Testing
- SPC4955, Saline 0.9%
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Santaris Pharma A/S
Hypertriglyceridemia, Insulin Resistance
Predictors of Response to Fenofibrate
Fenofibrate is one of the best options for treating hypertriglyceridemia. In the majority of patients, fenofibrate lowers triglycerides (TG) by 24-55% and improves HDL- and LDL-cholesterol.
- Trial name
- PreFar (NCT01023750)
- Testing
- Fenofibrate
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Immunological Status, Healthy Volunteers
Critical Food Ingredients on Immunocompetence to Prevent the Risk and Development of Obesity/Metabolic Syndrome
Double-blind cross-over intervention where the volunteers were randomized into two groups who, after receiving nutritional counseling, received two formulations in the form of a cookie: Group 1, commercial formulation and Group…
- Conditions
- Immunological Status, Healthy Volunteers, Healthy Volunteers - Male and Female
- Trial name
- CricoImNut (NCT07496320)
- Testing
- Administration of a commercial cookie formulation, Immunonutritional_2
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IMDEA Food
Acute Coronary Syndrome
Lipid Profile in Acute Coronary Syndrome
This study aims to assess the TG/Hdl-c ratio in patients with acute coronary syndrome as a novel marker of atherosclerosis.
- Trial name
- NCT05126043
- Testing
- Triglycerides/high density lipoprotein ratio
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Intermittent Fasting, Dyslipidemias
Intermittent Fasting in Dyslipidemia
World Health Organization report notifies of the escalating global burden of cardiovascular diseases (CVD), projecting that it will become the major worldwide cause of death and disability by 2020.
- Conditions
- Intermittent Fasting, Dyslipidemias, HDL Cholesterol, Low Serum, Hepatic Enzymes and Function Abnormalities
- Trial name
- NCT03805776
- Testing
- Fasting (diet restruction for specific period)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Metabolic Disorders, Abdominal Obesity
Exploring Physical Exercise for the Regulation and Control of Metabolic Disorders in College Students.
This clinical trial objective is to evaluate the effect of an aerobic physical exercise program on reducing triglycerides, blood pressure, abdominal obesity, altered glucose levels, and the increase in HDL in college-level…
- Conditions
- Metabolic Disorders, Abdominal Obesity, Blood Pressure Disorders, Hypertriglyceridemia
- Trial name
- (EPE_RCTMCS) (NCT06555159)
- Testing
- Physical exercise prescription: Continuous aerobic training (jogging, swimming, static cycling), Control group: Continuous aerobic physical exercise
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universidad de Colima
Dyslipidemias, Cardiovascular Risk Factor
Meta-analyses of Soy Protein and Its Food Sources for Cholesterol Reduction
Although soy protein has approved health claims in Canada and the US, and is recognized by major cardiovascular clinical practice guidelines for the reduction of cholesterol and risk of coronary heart disease (CHD), these claims…
- Conditions
- Dyslipidemias, Cardiovascular Risk Factor, Dysglycemia
- Trial name
- NCT04861545
- Testing
- Soy
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Dyslipidemias, Hypercholesterolemia
Dachundou No Sugar Added Soymilk for Lipid Modulation
Cardiovascular disease is one of the leading causes of death worldwide, and high cholesterol is a major risk factor. Diet is known to play an important role in managing blood lipids.
- Conditions
- Dyslipidemias, Hypercholesterolemia, Cardiovascular Diseases
- Trial name
- DNS Soymilk (NCT07175766)
- Testing
- Dachundou No Sugar Added Soymilk
- Where
- Taiwan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Obesity, Abdominal Obesity
Adiponectin, ICAM-1, VCAM-1 Levels and Metabolic Syndrome in Obese Adolescents
Adipose tissue secreting a number of adipokines which regulate insulin sensitivity, energy metabolism and vascular homeostasis, so the dysfunction of adipose tissue is linked with the incidence of obesity accompanied with insulin…
- Conditions
- Obesity, Abdominal Obesity, Metabolic Syndrome, Hypertension
- Trial name
- ICAM; VCAM (NCT05685017)
- Testing
- Nur Aisiyah Widjaja
- Where
- Indonesia
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universitas Airlangga
Dyslipidemia, Healthy Volunteers
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TAP311 in Healthy Subjects and Dyslipidemic Patients
This study will assess the safety, tolerability, and effect of TAP311 on blood lipids in healthy subjects and in patients who have dyslipidemia.
- Trial name
- NCT01487460
- Testing
- TAP311
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Overweight, Obesity
HDL Lipidomic, Proteomic and Functional Changes in Women After Eating Eggs
The objective of this randomized, single blinded cross-over study is to investigate effects of daily egg versus yolk-free egg substitute consumption on High Density Lipoprotein (HDL) composition and function in a population of…
- Trial name
- NCT02445638
- Testing
- Whole egg, Yolk-free egg
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Carpal Tunnel Syndrome (CTS), Biomarkers / Blood
Hematological and Metabolic Markers in Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy, but the severity of symptoms experienced by patients does not always correspond to abnormalities detected by nerve conduction studies.
- Trial name
- NCT06952647
- Where
- Turkey (Türkiye)
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital