Clinical trials: HEALTHY INDIVIDUALS
People With Diabetes
Development of a Novel Cookie Formulation and Evaluation of Its Effects on Glycemic Control in Healthy Individuals
This study will employ a randomized, open-label, crossover design to evaluate the glycemic response to newly developed cookie formulations.
- Trial name
- NCT07504016
- Testing
- Group A, Group B
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
COPD, Healthy Subjects
Sublingual Tonometry to Assess Tissue Perfusion in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Sublingual positioning of a silicon capillary system is applied. After 15 min, while the individual is in resting position with closed mouth and normal tidal breathing through the nose is performed, the silicon capillary system…
- Trial name
- subton (NCT01169506)
- Testing
- sublingual silicon capillary
- Where
- Hungary
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Szeged University
Blood Pressure
The Influence of Heart Rate Reduction Upon Central Arterial Pressure in Younger and Older Healthy Individuals
The purpose of this study is to determine the effect of slowing heart rate upon both central and peripheral blood pressures using a medication called Ivabradine which slows heart rate without affecting heart contraction, and to…
- Trial name
- NCT01029223
- Testing
- ivabradine, metoprolol
- Volunteers
- 42 people
- Sponsor
- Bayside Health
Hypoxia in Healthy Individuals
Hypoxia at Multiple Wavelengths of Light
The purpose of the study is to assess the effect of progressive, incremental hypoxia at multiple wavelengths of light.
- Trial name
- NCT01957891
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Nonin Medical, Inc
Parkinson Disease, Gaucher Disease
Detecting Dopaminergic Deficits in Individuals At-risk for Parkinsonism
The purpose of this study is to determine if participants have changes in dopamine cells in their brain using DaTSCAN™ brain imaging.
- Conditions
- Parkinson Disease, Gaucher Disease, Idiopathic Rapid Eye Movement Sleep Disorder
- Trial name
- NCT01358474
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy Participants
SP16 SERPIN-like Peptide Administration in Healthy Individuals
This study is a randomized, double-blind, placebo-controlled Phase 1 Clinical Trial of 24 healthy individuals to test the safety, tolerability and pharmacokinetics of a single subcutaneous administration of Serpin Peptide 16…
- Trial name
- NCT03651089
- Testing
- SP16
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Serpin Pharma, LLC
Stroke, Acute, Stroke (Subacute)
Inter-Limb Transfer in Acute Stroke
This study aims to investigate whether the improvements achieved through motor skill learning (MSkL) with the ipsilesional upper limb (UL) are transferred to the contralesional UL during the (sub)acute stroke phase, and to…
- Conditions
- Stroke, Acute, Stroke (Subacute), Healthy Individuals (Controls), Chronic Stroke Patients
- Trial name
- MLAS5 (NCT07822633)
- Testing
- REAplan®, Dextrain Manipulandum®
- Where
- 2 sites in Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Heart Failure
Digital App and Platform for Supporting Medicines Control and Optimization in Older Individuals With Heart Failure
The intervention being piloted in this study is a novel system of supporting older individuals (>60 years old) with heart failure to self-manage their chronic condition through the use at home of a digital health tool that…
- Trial name
- NCT05353803
- Testing
- Digital App and Platform for Supporting Medicines Control and Optimizationin Older Individuals With Heart Failure
- Where
- Spain
- Volunteers
- 9 people
- Sponsor
- Clinika de Kay SL
Healthy
The Effect Of Square Stepping Exercise Training On Cognitive Functions And Quality Of Life In Geriatric Individuals
This study was designed to investigate the effects of Square-Stepping Exercise Training on cognitive functions and quality of life in geriatric individuals.
- Trial name
- NCT06383910
- Testing
- Square Stepping Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Health Adults, Core Stabilization
Sacroiliac Manipulation and Core Stability in Healthy Adults
Sacroiliac joint (SIJ) dysfunction is a common cause of lumbopelvic instability, often linked to altered load transfer between the spine and lower limbs.
- Trial name
- SIJCORE (NCT07244679)
- Testing
- Sacroiliac Joint Manipulation (HVLA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Asthma, Dietary Intervention
Vegan Diet and Immune-Inflammatory Outcomes in Asthma and Healthy Adults
This randomized controlled study evaluates the effects of a balanced vegan diet compared with a balanced omnivorous diet on inflammatory and immune response markers and clinical asthma parameters in healthy adults and individuals…
- Conditions
- Asthma, Dietary Intervention, Vegan Diet
- Trial name
- VEGASTHMA (NCT07480369)
- Testing
- Omnivorous diet, Vegan diet
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Healthy Individuals, Arterial Hypertension
The Influence of Aircraft Noise Exposure on Renal Hemodynamic in Healthy Individuals
Epidemiological studies have found a link between aircraft noise exposure and increased incidence of arterial hypertension and thus cardiovascular disease.
- Trial name
- LÄRM (NCT02783456)
- Testing
- Noise, Silence
- Where
- Germany
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Balance Postural, Pain
Informational Manual Therapy to Improve Standing Balance
Objectives: The aim of this study is to assess the effect of Informational Manual Therapy (IMT) on quiet standing and quality of life in healthy individuals.
- Conditions
- Balance Postural, Pain, Quality of Life
- Trial name
- NCT04404829
- Testing
- Manual Therapy
- Where
- Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Breathing-Swallowing Coordination, Dysphagia Rehabilitation
Visual and Auditory Breathing-swallowing Coordinated Training
Dysphagia is caused by multiple factors, and respiratory-swallowing discoordination is considered to be one of the factors. The investigators recently developed a visual and auditory breathing-swallowing coordinated training…
- Trial name
- NCT04590391
- Testing
- Visual and Auditory Breathing-swallowing Coordinated Training device
- Where
- Japan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Hospital Organization Minami Kyoto Hospital
Muscle Function, Mitochondrial Function, Overweight
AMAZ-02 Effect on Exercise ToLerance in Healthy, Overweight Middle Aged Subjects (ATLAS Trial)
This is a Phase 2 randomized, double-blind, placebo-controlled study enrolling 90 healthy, overweight, middle aged subjects (30 placebo, 30 low dose and 30 high dose AMAZ-02 intervention), 40-65 years of age, who are otherwise…
- Conditions
- Muscle Function, Mitochondrial Function, Overweight, Healthy Aging
- Trial name
- ATLAS (NCT03464500)
- Testing
- Mitopure 500mg, Mitopure 1000mg
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Sepsis, Septic Shock
IL-40 and IL-41 Levels in Sepsis, Septic Shock, and Healthy Individuals
This study aims to investigate the blood levels of two recently identified immune-related proteins, Interleukin-40 (IL-40) and Interleukin-41 (IL-41), in patients with sepsis and its more severe form, septic shock.
- Conditions
- Sepsis, Septic Shock, Inflammation, Biomarkers
- Trial name
- NCT06963541
- Testing
- No intervention; Observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Melahat Yalcin Solak
Photobiomodulation, Fatigue
Photobiomodulation Effects on Fatigue and Muscle Damage Induced by NMES
Neuromuscular electrical stimulation (NMES) is widely used to improve muscle strength and mitigate atrophy. However, its clinical efficacy is often limited by early neuromuscular fatigue, muscle damage, and discomfort, which…
- Conditions
- Photobiomodulation, Fatigue, Discomfort, Electrical Stimulation
- Trial name
- NCT07602933
- Testing
- Active Photobiomodulation, NMES-evoked fatigue protocol
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Healthy Individuals
The Influence of Glutamate on Memory in Humans
The hippocampus is particularly laden with n-methyl-d-aspartate (NMDA) receptors, and is at the same time one of the most important sites in declarative memory.
- Trial name
- NCT00980408
- Testing
- Sugar pill, Glutamic Acid, Memantine
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Healthy Obesity, Metabolically
Natural Course of Initially Metabolic Healthy Obese Individuals (Healthy Obesity)?
The main goal of this study is to gain a thorough understanding, which specific factors drive the unhealthy sequelae of obesity. Therefore, the investigators want to understand: 1.
- Trial name
- NCT06799897
- Where
- Switzerland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Patients With Stable Coronary Artery Disease
Acute Hemodynamic and Biological Effects of ECP and Exercise
The purpose of this study in humans with stable coronary artery disease (CAD) treatable by percutaneous intervention (PCI) is to evaluate the efficacy of Enhanced External Counterpulsation (EECP) with regard to coronary…
- Trial name
- NCT02014090
- Testing
- Hemodynamic and biological measurements
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern