Clinical trials: HEALTHY INDIVIDUALS
Healthy Individuals
Ascending Glycan Dietary Supplementation in Healthy Adults
The investigators will conduct a parallel-group, placebo-controlled, randomized, double-blind ascending dose Phase I study of dietary supplementation in healthy individuals to evaluate safety and to determine the…
- Trial name
- NCT04466761
- Testing
- Monosaccharide Powder
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Nerve Block, Anesthesia, Local
Cutaneous Anesthesia of the Lateral Femoral Cutaneous Nerve
The purpose of this study is to investigate and describe the anatomical differences in distribution of the blocked area following a perineural LFCN (Lateral Femoris Cutaneous Nerve) block with either 8 ml or 16 ml of Ropivacaine…
- Conditions
- Nerve Block, Anesthesia, Local, Pain, Postoperative, Anatomical Distribution
- Trial name
- NCT03138668
- Testing
- Ropivacaine Injection
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Healthy Individuals
The Breakfast Study: How Different Aspects of Food Affect Eating
The purpose of this research study is to test how different aspects of food including food processing affect eating behaviors.
- Trial name
- NCT07525050
- Testing
- UPF breakfast/MPF breakfast, MPF breakfast/UPF breakfast
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Healthy Participants, Tobacco Smokers
Evaluation of the Effect of a Nasal Allergen Challenge With Dermatophagoides Farinae Extract on Nasal Airway Inflammation in Allergic Individuals, Comparing E-cigarette Users to Cigarette Smokers and Non-smokers.
The purpose of this pilot study is to evaluate allergen-induced nasal airway inflammation following nasal application of Dermatophagoides farinae (Der f), or house dust mite, extract in e-cigarette users, cigarette smokers, and…
- Trial name
- Mitey Nose (NCT03023397)
- Testing
- Der f
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy Volunteers
Inspiratory Muscle Endurance of Adults
The aim of this study is to determine the reference value ranges for healthy adults of the incremental threshold load test, which evaluates respiratory muscle endurance.
- Trial name
- NCT05237427
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Venous Sinus Thrombosis, Cranial
Anatomical Variation of Cerebral Venous Sinus in Healthy Individuals
The anatomical characteristics of veins and venous sinus result in great differences between cerebral venous system diseases and cerebral artery diseases in etiology, pathophysiology and clinical features.Therefore, understanding…
- Trial name
- NCT05413837
- Testing
- anotomy and variation of venous sinus, the level of biomarker in bood
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Mood Change, Emotion Regulation
Interoception and Emotion Regulation
The goal of this observational study is to examine the role of interoception in emotion regulation of negative mood in healthy individuals. Participants will fulfill several questionnaires and perform the Heartbeat Counting Task.
- Trial name
- INTEROEMOTION3 (NCT05684614)
- Testing
- Negative mood induction procedure, Spontaneous emotion regulation task, Positive mood induction procedure
- Where
- 3 sites in Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Healthy Individuals, Allergic Rhinitis
Health Effects of Wood Smoke and Traffic-Related Air Pollution Exposures: a Necessary Comparison
Accumulating evidence demonstrates that breathing air pollutants leads to devastating increases in sickness and death worldwide over time.
- Trial name
- WADE (NCT06749093)
- Testing
- Filtered Air (FA), Wood Smoke (WS), Diesel Exhaust (DE)
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy Individuals
Effect of Kinesthetic Motor Imagery on Heart Rate, Heart Rate Variability, and Skin Resistance
Motor Imagery (MI) is defined as imagining an action in the mind without any explicit physical movement. MI is considered an "offline" process of the motor areas of the brain.
- Trial name
- NCT06482528
- Testing
- Motor Imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Obesity
Alpha and Omega of Lifestyle Therapy
The study aims to investigate the effects of double-blinded, randomized placebo-controlled n3-fatty acid supplementation (1000 mg day-1) and 13 weeks of resistance training on muscle function/biology and systemic health in…
- Trial name
- Alpha&Omega (NCT04279951)
- Testing
- Resistance exercise, Omega-3
- Where
- Norway
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Inland Norway University of Applied Sciences
Gastrointestinal, Overweight , Obesity
A Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Impact of CLB101TM️ on Gut Health in Healthy, Overweight Individuals
Anaerostipes caccae CLB101TM️ is a next-generation probiotic isolated from healthy humans. It was shown to be in decreased abundance in people with protein-based food sensitivities/allergies.
- Trial name
- NCT07336615
- Testing
- CLB101™️
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- ClostraBio Inc.
Glycemic Response
Assessment of the Glycemic Responses to Nutritional Products (v2.0)
This study assesses the glycemic responses to nutritional products. During a study visit fasted subjects will consume one serving of the reference product or the test product.
- Trial name
- GLIN#2 (NCT05308147)
- Testing
- First Reference product, Second Reference product, Third Reference product
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Memory Decline, Healthy Subjects
In-Person Recruitment of Individuals to the Alzheimer's Prevention Trial (APT) Webstudy
Women, older adults, individuals from communities of color, particularly Black and Latino persons, and individuals with lower socioeconomic status are historically underrepresented in clinical research.
- Trial name
- FIND-AD Aim 2 (NCT07218120)
- Testing
- Financial Incentive, Active Comparator #1
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Healthy Volunteers Only
Effects of Substance P on Headache Induction in Healthy Individuals
Substance P is a signaling molecule that has been implicated in the pathogenesis of headache. This study aims to ascertain whether administration of substance P can induce headache in healthy adults.
- Trial name
- NCT06632080
- Testing
- Substance P
- Where
- Denmark
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Healthy Volunteers, Spinal Cord Injury
Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
This is an early feasibility trial to determine whether transcutaneous neuromuscular electrical stimulation, with or without transcutaneous spinal cord stimulation, using an investigational neurostimulation device improves…
- Conditions
- Healthy Volunteers, Spinal Cord Injury, Stroke, Paralysis
- Trial name
- NCT04755699
- Testing
- Transcutaneous Electrical Stimulation
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Low Intensity Knee Gonalgia
Effect of Yogurts Supplemented With Mobilee on Joint Function in Healthy Individuals With Joint Discomfort
The purpose of this study is to determine whether the daily eating of a yogurt supplemented with Mobile is effective in improving joint function and quality of life of individuals with low intensity gonalgia.
- Trial name
- NCT01303432
- Testing
- Yogurt supplemented with Mobilee, Yogurt
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bioiberica
Central Auditory Disease, Auditory Processing Disorder, Central
taVNS Effect on Central Auditory Processing
The behavioral effects of vagus nerve stimulation (VNS) and observed activation in the auditory cortex with transcutaneous auricular VNS (taVNS) raise questions about their potential impact on auditory processing.
- Conditions
- Central Auditory Disease, Auditory Processing Disorder, Central, Auditory Processing Disorders, Vagus Nerve Stimulation
- Trial name
- NCT06970444
- Testing
- transcutaneous auricular vagus nerve stimulation (taVNS)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Medipol University
No Condition, Healthy Individuals
Protein Intake Distribution to Support Muscle Anabolism in Healthy Young Adults
The purpose of the study is to evaluate whether the distribution pattern of daily protein intake affects how much muscle protein can be built in the muscle after resistance exercise and at rest.
- Trial name
- NCT07245199
- Testing
- protein intake
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Diabetes Mellitus Type 1, Diabetes Mellitus Type 2
Assessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy Individuals
Patients with diabetes have high blood sugar levels (hyperglycemia) because pancreatic beta-cells no longer produce sufficient insulin.
- Trial name
- NCT00813228
- Testing
- Sitagliptin (Januvia)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Sarcopenia, Skeletal Muscle Atrophy
Plant Protein Blend and Milk Protein Supplements in Older Individuals
Background Protein intake is important for skeletal muscle mass maintenance with aging and the ingestion of specifically-timed protein supplements could increase overall protein intake and thereby contribute to skeletal muscle…
- Conditions
- Sarcopenia, Skeletal Muscle Atrophy, Protein Malnutrition
- Trial name
- Blend-D2O (NCT06403137)
- Testing
- Resistance exercise, Standardized diet, Plant protein supplement
- Where
- Netherlands
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center