Clinical trials: HEART ARREST
Labor, Obstetric
Effect of Tafoxiparin to Treat Primary Slow Progress of Labor Including Prolonged Latent Phase and Labor Arrest
The study will be designed as a double-blind, placebo-controlled, parallel-group, dose-finding study with one group treated with placebo and three groups treated with tafoxiparin in three different infusion concentration levels…
- Trial name
- NCT03001193
- Testing
- DF 01, Oxytocin
- Where
- 12 sites in Denmark, Finland and 1 more
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- Dilafor AB
Infertility, Male, Infertility Unexplained
Using of Testes Shocker in Improving the Spermatogenesis and Sperms Activity
Infertility was reported in approximately 15% of all heterozygous couples, with male factor accounting for nearly half the cases.
- Conditions
- Infertility, Male, Infertility Unexplained, Infertility Due to Complete Spermatogenic Arrest, Oligospermia
- Trial name
- NCT05506722
- Testing
- Testes shocker
- Where
- Iraq
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Quality of Cardio-pulmonary Resuscitation
Registry of Laypeople's CPR Performance
The aim of the registry is to collect laypeople's performance after a BLS/AED course carried out with the use of feedback devices.
- Trial name
- NCT03185260
- Where
- 5 sites in Italy, Switzerland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Pavia nel Cuore
Pulmonary Embolism, Respiratory Failure
Construction of Early Warning Model for Pulmonary Complications Risk of Surgical Patients Based on Multimodal Data Fusion
The goal of this observational study is to establish an intelligent early warning system for acute and critical complications of the respiratory system such as pulmonary embolism and respiratory failure.
- Conditions
- Pulmonary Embolism, Respiratory Failure, Infection Complication, Cardiac Arrest
- Trial name
- NCT06057688
- Where
- China
- Volunteers
- 1,770 people, healthy volunteers welcome
- Sponsor
- Renrong Gong
Extracorporeal Membrane Oxygenation Complication, ARDS (Acute Respiratory Distress Syndrome)
RECOMMEND Platform Trial
The goal of this platform trial is to determine the efficacy, safety and cost-effectiveness of various interventions in patients with acute cardiorespiratory failure requiring extracorporeal membrane oxygenation (ECMO) The main…
- Conditions
- Extracorporeal Membrane Oxygenation Complication, ARDS (Acute Respiratory Distress Syndrome), Intensive Care Medicine, Cardiac Arrest (CA)
- Trial name
- RECOMMEND (NCT06526533)
- Testing
- Liberal RBC Transfusion, Restrictive RBC Transfusion
- Where
- 3 sites in Australia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Death, Sudden, Cardiac, Arrythmia
Monitoring of Arrhythmias in Patients Treated With Antipsychotics
Antipsychotics may be associated to life-threatening arrhythmias and sudden cardiac death. This is the fist study to estimated the arrhythmic burden using long-term monitoring by implantable loop recorder in patients treated with…
- Conditions
- Death, Sudden, Cardiac, Arrythmia, Antipsychotics and Neuroleptics Toxicity
- Trial name
- MAPP (NCT04575103)
- Testing
- Antipsychotic
- Where
- 18 sites in Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Brugada Syndrome, Sudden Cardiac Death Due to Cardiac Arrhythmia
DNA Methylation in Brugada Syndrome and Risk of Sudden Cardiac Death
The goal of this observational study is to evaluate if there are differences in DNA methylation of peripheral blood in patients with Brugada syndrome and healthy subjects.
- Trial name
- ANDROMEDA (NCT06888271)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Quality of Life, Malnutrition
Clinical Study of Novel Probiotic Microbial Composite™ to Treat Undernourished Young Children
This study is to determine if a novel bio-fermented Microbiotic Composite™ can improve the digestive health and subsequent growth and quality of life parameters in a selected group of children in a district in India.
- Conditions
- Quality of Life, Malnutrition, Growth Arrest
- Trial name
- NCT03150927
- Testing
- Probiotic Microbial Composite
- Where
- India
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Biowish Technologies, Inc.
Stable Angina, Unstable Angina
Serum Uric Acid Levels and Onset of Cardiovascular Diseases: a CALIBER Study
Serum uric acid level is a commonly measured biomarker. The association between serum uric acid level and the risk of developing cardiovascular diseases has been observed in some studies, while others showed controversial…
- Conditions
- Stable Angina, Unstable Angina, Myocardial Infarction, Unheralded Coronary Heart Disease Death
- Trial name
- NCT03425305
- Volunteers
- 180,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Inherited Cardiac Conditions, Sudden Cardiac Arrest
Using Heart Electrical Signals to Study How Well Treatments Prevent Dangerous Heart Rhythms in Active People
The goal of this observational study is to learn if two specific heart electrical signal patterns can help in detecting the risk of dangerous heart rhythms in athletes, and to see if exercise-based tests can be used instead of…
- Conditions
- Inherited Cardiac Conditions, Sudden Cardiac Arrest, Ventricular Arrhythmia, Athlete
- Trial name
- ULTIMATE-A (NCT07014579)
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Cardiac Arrest, Intubation, Endotracheal
Pediatric Intubation Among Nursing
The aim of this study was to compare time, success rates of video laryngoscope and direct laryngoscope for the emergency intubation with an immobilized cervical spine in a standardized pediatric manikin model.
- Trial name
- NCT02291640
- Testing
- MIL, CoPilot
- Where
- Poland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Cardiac Arrest, Hyperventilation
Investigation of a Novel Turbine-driven Ventilator for Use in Cardiopulmonary Resuscitation
The objective of this study is to determine whether healthcare professionals trained in CPR can deliver more effective ventilations during CPR using the Handivent, a novel turbine-driven ventilator as compared to bag-valve-mask…
- Trial name
- NCT02743299
- Testing
- Handivent Ventilator
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Utah
Out-Of-Hospital Cardiac Arrest, Mobile Phone Use
Impact of Mobile Phone Application Use on Adult BLS
The aim of the study is to investigate whether a serious smartphone game (called MOBI-CPR game) used in the home environment has an impact on the retention of adult basic life support knowledge and skills.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Mobile Phone Use, Stress, Knowledge, Attitudes, Practice
- Trial name
- MOBI-CPR (NCT05784675)
- Testing
- MOBI-CPR game
- Where
- Slovenia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nino Fijačko
Out-Of-Hospital Cardiac Arrest
Dispatcher-Assisted CPR: Low-Dose, High-Frequency Simulation-Based Training
Clear, concise, yes, and no answers can be challenging to achieve in the assessment of consciousness and breathing in out-of-hospital cardiac arrest (OHCA) calls.
- Trial name
- NCT04085692
- Testing
- Low-Dose, High-Frequency Simulation-Based Training
- Where
- Denmark
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Post Traumatic Stress Disorder, Resuscitated Sudden Cardiac Death
Psychological Sequelae After Sudden Cardiac Death in the Patient and His Relatives
This study will evaluate and describe the occurrence of Acute traumatic stress and persistence of Post Traumatic Stress Disorder (PTSD) after resuscitated sudden cardiac death (SCD) in patient and relatives present during the…
- Trial name
- TEMPO (NCT04921514)
- Testing
- SASRQ questionnaire, PCL-5 with LEC-5 questionnaire
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Chronic Kidney Disease, Cardiovascular Morbidity
Chemoreflex Sensitivity in Chronic Kidney Disease
Cardiovascular morbidity and mortality are markedly increased in chronic kidney disease (CKD) and may be explained in part by sympathetic hyperactivity.
- Trial name
- NCT00794872
- Testing
- blood sampling
- Where
- Germany
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Sudden Cardiac Death, Cardiac Arrhythmias
Cardiovascular Pre-participation Screening in Children and Adolescents
Sports participation is strongly encouraged in children and adolescents, but intense training at early ages may reveal hidden heart conditions that increase the risk of sudden cardiac death.
- Trial name
- NCT07862504
- Testing
- Pre-participation clinical evaluation, Diagnostic Test: Resting 12-lead electrocardiogram, Diagnostic Test: Step test (Harvard step test)
- Where
- Brazil
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Out-Of-Hospital Cardiac Arrest, Healthy
Dose-Finding Study of Intranasal Insulin in Healthy Participants Insulin in Healthy Participants
This study is to determine the safety and tolerability of regular insulin (Humulin R) when given intranasally (as drops in nostrils).
- Trial name
- NCT05062785
- Testing
- Intranasal insulin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Robert Silbergleit
Safety Issues, Communication
Personal Protective Equipment Affect Team Performance During Medical Emergencies
Safety of healthcare professionals working in high-risk environments is of upmost importance. Personal protective equipment (PPE) may affect the performance of individuals and teams by altering their senses, manual skills and…
- Conditions
- Safety Issues, Communication, Cardiopulmonary Arrest
- Trial name
- PPE-TEAM (NCT04742426)
- Testing
- WHO recommended PPE, Super-safe setup
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Roman Sýkora
Code Status Discussions With Medical In-patients
Checklist-guided Shared Decision-making for Code Status Discussions in Medical Inpatients.
This cluster-randomized, multicenter trial is designed to investigate the effect of checklist-guided shared decision-making including decision aids and communication of expected outcome on patients' decision regarding their code…
- Trial name
- NCT03872154
- Testing
- Checklist-guided shared decision-making
- Where
- Switzerland
- Volunteers
- 2,663 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland