Clinical trials: HEART ARREST
Cardiac Arrest, Sudden Death, Cardiac
Use of Public Access Defibrillators by Untrained Bystanders
Survival from out-of-hospital cardiac arrest is time critical and diminishes rapidly without appropriate intervention. Bystander CPR at least doubles the chances of survival and the additional use of a public access defibrillator…
- Trial name
- NCT03230773
- Testing
- Defibrillator model
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Cardiac Arrest
A Modified Delphi for ECPR Post Resuscitation Care
The objective of this study is to generate expert consensus statements on the management of out of hospital cardiac arrest (OHCA) patients treated with extracorporeal membrane oxygenation (ECMO) cardiopulmonary resuscitation…
- Trial name
- NCT06552312
- Testing
- Delphi Questionnaire
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sydney Local Health District
Pediatric Cardiac Arrest (Simulated)
Examining the Effect of a Scripted Debriefing on Resuscitation Performance in Pediatrics
The investigative team's purpose for conducting this research is to improve effective and efficient translation and implementation of evidence based advanced life support practice to providers of care for children.
- Trial name
- EXPRESS (NCT01682629)
- Testing
- Debriefing Script, High Physical Realism Simulation
- Where
- Canada
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Sports Accident, Athletes Heart
Lithuanian Atletes' Aortic Diameter
Recent developments in football have seen the sudden death of young football player due to aortic rupture hence reinforcing the controversy of football as a field with substantial risk for sudden cardiac arrest and death.
- Trial name
- NCT03656861
- Testing
- Physical load
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Agne Slapsinskaite
Abdominal Aortic Aneurysm, Coronary Heart Disease NOS
Social Deprivation and Initial Presentation of 12 Cardiovascular Diseases: a CALIBER Study
Study of heterogeneity in associations between social deprivation and the initial presentation of 12 cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease NOS, Unheralded Corronary Death, Intracerebral Haemorrhage
- Trial name
- IP4 (NCT01937065)
- Testing
- No treatment
- Where
- United Kingdom
- Volunteers
- 1,937,360 people, healthy volunteers welcome
- Sponsor
- University College, London
Prolonged Second Stage of Labor
Trial of IV NTG for CD After Second Stage Arrest for the Prevention of Uterine Extension
Randomized controlled clinical trial of IV nitroglycerin at cesarean delivery for second stage arrest of descent to prevent or uterine extension at the hysterectomy site.
- Trial name
- NITRO (NCT02265965)
- Testing
- intravenous nitroglycerin
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cardiac Arrest, Sudden, Cardiopulmonary Resuscitation (CPR)
The Influence of the Thoracic Stiffness of CPR Teaching Manikins on the Accuracy of Compression in Cardiopulmonary Resuscitation
This study was a multicenter, prospective, randomized controlled, parallel single-blind study. The purpose of this study is to analyze the effect of compression quality by controlling the thoracic stiffness.
- Conditions
- Cardiac Arrest, Sudden, Cardiopulmonary Resuscitation (CPR), Manikins
- Trial name
- NCT07861841
- Testing
- different elasticity coefficients of the manikin device
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Tang Ziren
Pediatric ALL, Cardiac Arrest
Effect of IAM With an I-gel® on Ventilation Parameters in Simulated Pediatric OHCA
Pediatric cardiac arrest occurs most in the prehospital setting. Most of them are due to respiratory failure (e.g., trauma, drowning, respiratory distress), where hypoxia leads to cardiac arrest.
- Conditions
- Pediatric ALL, Cardiac Arrest, Cardiopulmonary Arrest, Resuscitation
- Trial name
- NCT05498402
- Testing
- i-gel ® device, bag-valve-mask ventilation
- Where
- 4 sites in Switzerland
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances
Cardiac Arrest
Comparison of Bystander Fatigue and CPR Quality When Using Two Different CPR Ratios.
STUDY OBJECTIVES The overall goal of this study is to compare bystander fatigue and CPR quality after 5 minutes of the new 30:2 versus the old 15:2 chest compression to ventilation International Resuscitation Guidelines, in a…
- Trial name
- NCT00380757
- Testing
- bystander CPR using 30:2 ratio vs 15:2 ratio
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Cardiopulmonary Arrest With Successful Resuscitation
Cardiopulmonary Resuscitation Self-training
Participants were 45 first-year medical students randomly assigned to cardiopulmonary resuscitation (CPR) self-training using either a video-based presentation or a serious game developed in a 3D learning environment for up to 20…
- Trial name
- NCT03729037
- Testing
- CPR self-training
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Bystander, Chest Compression
REsuscitation Survey of Police Officers in New Taipei City for Duty
Out-of-hospital cardiac arrest (OHCA) remains a time-critical emergency where early cardiopulmonary resuscitation (CPR) and timely defibrillation using an automated external defibrillator (AED) are key to improving survival and…
- Conditions
- Bystander, Chest Compression, Out of Hospital Cardiac Arrest, AED
- Trial name
- RESPOND (NCT06955351)
- Testing
- Survey by Questionnaire
- Where
- Taiwan
- Volunteers
- 4,867 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Cardiac Arrest (CA)
V-CPR Under Special Circumstances
Out-of-hospital cardiac arrest (OHCA) remains a major cause of death globally, with bystander CPR rates varying widely (13-82%) despite public health efforts.
- Trial name
- NCT07101510
- Testing
- sV-CPR, V-CPR, T-CPR
- Where
- Hungary
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Critical Illness, Cardiac Arrest
Swecrit Biobank - Blood Samples From Critically Ill Patients and Healthy Controls
Blood samples are collected and stored in a biobank for later analysis of circulating substances in peripheral blood and genetic variations in patients with severe critical illness and risk of death.
- Conditions
- Critical Illness, Cardiac Arrest, Sepsis, Influenza
- Trial name
- SWECRIT (NCT04974775)
- Testing
- Blood collection, Blood collection, serial sampling
- Where
- 4 sites in Sweden
- Volunteers
- 8,500 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Cardiac Arrest
Use of a Hand-held Digital Cognitive Aid in Simulated Cardiac Arrest.
Cardiac arrest is one of the most stressful situations to be managed. Our first study (MAX, accepted for publication BJA) clearly showed that it could not be compared to other urgent and stressful situations (malignant…
- Trial name
- SIMMAX2 (NCT03253770)
- Testing
- SIMMAX2
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Claude Bernard University
Dental Caries
LT Comparative Effectiveness of 2 Caries Treatments
This study is a continuation of a cluster randomized clinical trial (cRCT) conducted in 33 publicly subsidized housing facilities/sites (HUD Section 202) and other low-income housing voucher programs in NE Ohio.
- Trial name
- NCT07213661
- Testing
- A "simple medical strategy" consisting of silver diamine fluoride (SDF), A "typical dental strategy" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride Varnish (FV)
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Dysfunctional Labor
Trial of Oxytocin Alone Versus Oxytocin and Propranolol for the Treatment of Abnormal Labor
The purpose of this study is to determine whether propranolol is better than oxytocin for the treatment of labor abnormalities. The endpoint is the rate of vaginal delivery experienced by women receiving prolonged oxytocin versus…
- Trial name
- NCT00315913
- Testing
- Propranolol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Cardiac Arrest, Out-Of-Hospital
Drone Delivered Defibrillators (The 3D Project).
The goal of this observational study is to explore the optimisation and integration of a drone-delivered Automated External Defibrillator (AED) system into the pre-hospital response to out-of-hospital cardiac arrest.
- Trial name
- NCT06334718
- Testing
- Interviews and simulation
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Warwick
Cardiopulmonary Arrest, Cardiac Arrest
Evaluation of the InterFACE-AR System for Cardiopulmonary Arrest
Cognitive aids are decision support tools that present prompts to encourage recall of information, thus freeing up mental resources to increase the likelihood of desired behaviors.
- Trial name
- InterFACE-AR (NCT06411327)
- Testing
- Augmented reality, LCD Screen
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Cardiovascular Diseases, Cardiovascular Diseases Risk
Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care Pathways
Cor360 is an observational study evaluating whether extended wearable electrocardiogram (ECG) data can support broad-spectrum cardiac phenotyping and risk assessment beyond conventional single-purpose ambulatory rhythm…
- Conditions
- Cardiovascular Diseases, Cardiovascular Diseases Risk, Cardiac Conduction System Disease, Bundle/Fascicular Abnormalities
- Trial name
- Cor360 (NCT07775976)
- Testing
- COR Wearable ECG Monitoring, Cor360 Clinician-Facing Decision-Aid Reporting
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Psychologic Stress, Heart Arrest
Analysis of the Stress Induced by in Situ Simulation
Vulnerability to psychologic distress induced by in situ simulation. Objectives: Psychological evaluation at short and long term on working satisfaction, mental health, and acute stress after in situ simulation.
- Trial name
- SIMSTRESS (NCT02494089)
- Testing
- distress analysis
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon