Clinical trials: HEART RATE
Vagus Nerve Stimulation, Autonomic Nervous System
Frequency-Dependent Effects of Auricular Vagus Nerve Stimulation on Autonomic and Cardiovascular Parameters
This randomized, sham-controlled, crossover study investigates the acute autonomic effects of transcutaneous cervical vagus nerve stimulation (tcVNS) applied at five different frequencies (0 Hz/sham, 10 Hz, 25 Hz, 50 Hz, 100 Hz)…
- Conditions
- Vagus Nerve Stimulation, Autonomic Nervous System, Heart Rate, Blood Pressure
- Trial name
- AVNS-DRC (NCT07274332)
- Testing
- Pulsetto FIT™ - tcVNS 10 Hz, Pulsetto FIT™ - tcVNS 25 Hz, Pulsetto FIT™ - tcVNS 50 Hz
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Heart Rate Variability
Effects of Repetitive Transcranial Magnetic Stimulation on Heart Rate Variability
Repetitive transcranial magnetic stimulation is a non-invasive neuromodulation technique used to treat different neuropsychiatric disorders, such as, depression, neuropathic pain, fibromyalgia and obsessive-compulsive disorder.
- Trial name
- TMSXHRV (NCT03739489)
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Aging, Alzheimer Disease
Heart Rate and Breathing Effects on Attention and Memory
In the current study, we will examine how daily paced breathing affects plasma amyloid beta levels and the rate of learning in older adults.
- Conditions
- Aging, Alzheimer Disease, Age-related Cognitive Decline
- Trial name
- HeartBEAM (NCT05602220)
- Testing
- Brain training, Paced breathing
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Behavior, Social, Autonomic Imbalance
Coping Strategies and Responsiveness to a Brief Online Intervention During COVID-19 Pandemic
The present study investigates the efficacy of a brief and cost-effective video-intervention that combines bottom-up elements of deep breathing and third-wave cognitive behavioral therapy techniques (i.e., mindfulness and…
- Trial name
- NCT04382560
- Testing
- Deep Breathing training, Compassion focused intervention
- Where
- Italy
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Parma
Warm Footbath, Cardiovascular System
Temperature-dependent Changes in Cardiovascular Parameters During Warm Water Footbaths in Healthy Women
A study to explore whether different temperatures of warm water footbaths have different effects on the cardiovascular system, the autonomic nervous system and the general well-being of healthy women.
- Conditions
- Warm Footbath, Cardiovascular System, Autonomic Nervous System
- Trial name
- NCT04579497
- Testing
- 38°C warm water footbath, 40°C warm water footbath, 42°C warm water footbath
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Endoscopic Sinus Surgery, Heart Rate
Comparative Study Between the Efficacy of Verapamil and Bisoprolol on Reduction of Bleeding During Endoscopic Sinus Surgery Under General Anaesthesia.
The study aims to compare the effect of addition of verapamil and Bisoprolol to general anasthesia aimed reduction in heart rate and blood loss during endoscopic sinus surgery.
- Conditions
- Endoscopic Sinus Surgery, Heart Rate, Blood Loss
- Trial name
- NCT04356196
- Testing
- Verapamil, Bisoprolol
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Assiut University
Atrial Fibrillation, Stroke
Wearable ECG for AF Screening and Stroke Risk Assessment
This study aims to evaluate the application of wearable ECG garments in atrial fibrillation (AF) screening and stroke risk assessment.
- Trial name
- NCT06907264
- Testing
- Wearable ECG Garment for Continuous Atrial Fibrillation Screening and Stroke Risk Assessment
- Where
- 2 sites in China
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Elderly Subjects, Respiration Exercises
Effects of Respiratory Yoga Training on Heart Rate Variability and Baroreflex of Healthy Elderly Subjects
The decreases of physiological capacities which take place with senescence include diminishing respiratory capacity as well as a reduction of heart rate variability and baroreflex sensibility.
- Trial name
- NCT00969345
- Testing
- Stretching Exercises, Respiratory Exercises conducted twice a day for 10 minutes
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Infant Development
A Pilot Study Using Photo-plethysmographic (PPG) Camera
The researcher want to use video signals to monitor heart rate, respiration rate and oxygen saturation using Photo-plethysmography (PPG) as the underlying mechanism for the method: periodic changes in skin reflectance, induced by…
- Trial name
- NCT01166867
- Testing
- Photo-plethysmography monitoring
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Depressive Disorder, Major
Probiotics and the Gut Brain Axis- Do Probiotics Interact With the Vagal Nerve?
The purpose of this study is to investigate the effects of a multispecies probiotic on the function of the vagal nerve in patients with major depression and healthy participants in a single-center, randomized, placebo-controlled…
- Trial name
- ProBIO-HRV (NCT04772664)
- Testing
- Multispecies-Probiotic
- Where
- Austria
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Autonomic Dysfunction
Cardiac Autonomic Modulation in Older Hypertensive Individuals Submitted to Different Types of Physical Training
Sixty-one sedentary older hypertensive individuals were randomized to four groups: continuous aerobic training (CA), interval aerobic training (IA), resistance training (R), and control (C) group.
- Trial name
- NCT05135247
- Testing
- Exercise
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Stress, Stress, Psychological
The Effect of SKY Breath Meditation on Health and Well-being
The goal of this pilot SKY (Sudarshan Kriya Yoga) Breath Meditation study is to establish feasibility and acceptability of the intervention; and investigate preliminary effectiveness of the intervention at the DNA methylation…
- Conditions
- Stress, Stress, Psychological, Stress, Physiological, Anxiety
- Trial name
- NCT05523414
- Testing
- SKY
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Labor
Impact of Prophylactic Ephedrine on Fetal Heart Tracing and Uterine Tetanic Contraction After CSE
Labor analgesia is an important component of the care of laboring patients. A known side effect of combined spinal and epidural anesthesia (a type of labor analgesia) is an increased incidence of category II fetal heart rate…
- Trial name
- NCT05873218
- Testing
- Ephedrine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Psychological Trauma
A Couples' Intervention Protocol for PTSD
Posttraumatic stress disorder (PTSD) is a multifaceted disorder resulting from intense and/or life-threatening trauma. PTSD sequelae often have a ripple effect on close others, including spouses and children.
- Trial name
- NCT05045859
- Testing
- CBCT for PTSD
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Healthy, Exercise
Heart Rate Changes During Normal Activity, Exercise, and Sleep in Normal Healthy Subjects With and Without Epilepsy
The purpose of this study is to gather ECG data during normal activity, exercise, and sleep from normal subjects with or without well-controlled epilepsy.
- Trial name
- NCT01202682
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cyberonics, Inc.
Effects of; Food, Thermogenesis
Thermogenic Effect and Metabolic Responses of Durian
The primary aim of this study is to determine the effectiveness of durian on thermic effect of food (TEF), blood pressure, heart rate and postprandial glucose and lipid levels in young healthy men and women, compared to the…
- Conditions
- Effects of; Food, Thermogenesis, Blood Pressure, Heart Rate
- Trial name
- NCT06121817
- Testing
- Food/meal intervention
- Where
- Singapore
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Exercise Response, Physical Fitness
Heart Rate Vs. Race Pace-Based Prescription Training in Recreational Distance Runners
The goal of this randomized controlled trial is to compare adherence to training prescription-defined as the percentage of time spent within the prescribed intensity zone-using either a race pace-based method or a heart…
- Conditions
- Exercise Response, Physical Fitness, Athletic Performance, Running Endurance
- Trial name
- NCT07109089
- Testing
- Race Pace-based training, Heart Rate-Based Training
- Where
- Spain
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Cerebral Hypoxia
The Effects of Hypobaria vs Hypoxia on Cerebral Functions.
The investigators will investigate the effect of hypobaria and hypoxia on physiological responses such as: oxygen saturation, heart rate, cerebral blood flow, cerebral oxygenation, brain's activity and concentration performance.
- Trial name
- Hypoxia (NCT03303118)
- Testing
- Hypoxia
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Fliegerärztliches Institut
Autonomic Neuropathy
A Comparison Between Pupillometry, Heart Rate Variability and Metaiodobenzylguanidine Scintigraphy for the Diagnosis of Early Diabetic Autonomic Neuropathy in Type 1 Diabetes
This study will examine if one of the following methods: pupillometry, spectral analysis of heart rate variability and metaiodobenzylguanidine scintigraphy, is more capable to detect early diabetic autonomic neuropathy in…
- Trial name
- NCT01822431
- Testing
- metaiodobenzylguanidine scintigraphy
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- AHEPA University Hospital
Healthy Young Adults, Physical Activity Levels
Differences in Autonomic Recovery Between Physically Active and Inactive Women Following an Automated Massage Chair Intervention
The goal of this study is to investigate whether an automated massage chair can improve the body's recovery system in healthy young women (aged 19-26 years) who are either physically active or inactive.
- Conditions
- Healthy Young Adults, Physical Activity Levels, Inactive People
- Trial name
- NCT07529678
- Testing
- Massage chair
- Where
- Malaysia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia