Clinical trials: HIPEC
Peritoneal Carcinosis, Peritoneal Metastases
Impact of an Omega-3 Enriched Oral Nutritional Supplement on Improving Surgical Outcomes in Patients With Peritoneal Carcinomatosis Undergoing Cytoreductive Surgery
The OMNI study is a clinical trial investigating whether a nutritional supplement with added Omega-3 fatty acids can improve surgical outcomes for patients with peritoneal carcinomatosis.
- Conditions
- Peritoneal Carcinosis, Peritoneal Metastases, HIPEC, Cytoreductive Surgery
- Trial name
- OMNI (NCT07478432)
- Testing
- ONS enriched with Omega-3, Standard ONS
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Catholic University of the Sacred Heart
Colorectal Cancer, Raltitrexed
Raltitrexed in HIPEC
To evaluate the tolerance of patients with colorectal cancer to hyperthermic intraperitoneal chemotherapy with Raltitrexed, to determine the safety, tolerability, PK, and efficacy.
- Conditions
- Colorectal Cancer, Raltitrexed, HIPEC
- Trial name
- NCT04761185
- Testing
- Raltitrexed
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Fudan University
Epithelial Ovarian Cancer, Platinum Resistant
CRS & HIPEC for Platinum-Resistant Recurrent Ovarian Cancer (KOV-02R, RECOVER)
Platinum-resistant recurrent epithelial ovarian cancer randomizing with or without cytoreductive surgery + hyperthermic intraperitoneal chemotherapy (HIPEC): KOV-02R, RECOVER
- Conditions
- Epithelial Ovarian Cancer, Platinum Resistant, Recurrent Ovarian, HIPEC
- Trial name
- KOV-HIPEC-02R (NCT05316181)
- Testing
- HIPEC
- Where
- 3 sites in South Korea
- Volunteers
- 140 people
- Sponsor
- National Cancer Center, Korea
HIPEC, Gastro Intestinal Cancer
Effects of HIPEC on Postoperative Bowel Motility and Complications
This retrospective cohort study was conducted at our institution, involving patients with gastric cancer, appendiceal mucinous neoplasm, or colon cancer who underwent CRS with or without HIPEC between January 2017 and December…
- Conditions
- HIPEC, Gastro Intestinal Cancer, Adhesion Prevention, Bowel Functions
- Trial name
- NCT07353177
- Testing
- Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
- Where
- China
- Volunteers
- 193 people
- Sponsor
- Peking University People's Hospital
Gastric Cancer (GC), HIPEC
Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Gastric Cancer
The study investigates the outcomes of hyperthermic intraperitoneal chemoperfusion (HIPEC) in combination with curative-intent gastrectomy in resectable locally-advanced and limited-metastatic (low peritoneal cancer index)…
- Conditions
- Gastric Cancer (GC), HIPEC, Peritoneal Metastases From Gastric Cancer, Hyperthermic Intraperitoneal Chemoperfusion
- Trial name
- G-PEC (NCT07313579)
- Testing
- curative-intent surgery + HIPEC
- Where
- Ukraine
- Volunteers
- 200 people
- Sponsor
- Ukrainian Society of Clinical Oncology
HIPEC
Thermodynamic Model of Hyperthermia in Humans Undergoing HIPEC
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is a well-established alternative for patients with peritoneal surface malignancies.
- Trial name
- HIPEC (NCT05426928)
- Testing
- Additional temperature monitoring/recording
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Henry Ford Health System
HIPEC, Ovarian Serous Adenocarcinoma
Evaluating the Efficacy of Hyperthermic Intraperitoneal Treatment to Enhance the Sensitivity of Immune Checkpoint Inhibitor in Patients With Advanced Ovarian Cancer： A Single-arm Study
Background: Advanced ovarian cancer is a highly dangerous disease, and many patients lose their lives due to limited treatment effectiveness.
- Trial name
- ICI-HIPET (NCT07068178)
- Testing
- ICI-HIPET
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jing Li
Hemodynamics, Cytoreductive Surgery
HIPEC Surgery and Hemodynamics
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) involves the intraoperative administration of heated chemotherapeutic agents into the abdominal cavity following cytoreductive surgery (CRS).
- Conditions
- Hemodynamics, Cytoreductive Surgery, Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
- Trial name
- NCT06922227
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Miray Gözde Özdemir
Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
Noradrenaline Infusion Versus Phenylephrine Infusion in Improving Serum Lactate Level in HIPEC
ABG PARAMETERS ARE CHANGED DURING HIPEC, WE TRIED TO FIND COMPARISON BETWEEN NORADRENALINE AND PHENYLEPHRINE IN OPTIMIZING ABG PARAMETERS THAT REFLECTS ORGAN PERFUSIONS ESPECIALLY SERUM LACTATE
- Trial name
- NCT04144465
- Testing
- NORADRENALIN, PHENYLEPHRINE
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Suez Canal University
Gastric Cancer, HIPEC, Anti-PD-1 Antibody Camrelizumab (SHR-1210), Chemotherapy and Surgery
HIPEC Combined With Camrelizumab, Paclitaxel and S-1 for Conversion Therapy in Patients With Advanced Gastric Cancer With Peritoneal Metastasis
There is no currently available treatment for peritoneal metastasis of gastric cancer. Hyperthermic intraperitoneal chemotherapy (HIPEC) can not only maintain the high concentration of drugs in the abdominal cavity, but also…
- Trial name
- NCT04889768
- Testing
- HIPEC, anti-PD-1 antibody Camrelizumab (SHR-1210), Chemotherapy and Surgery
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Zhejiang Cancer Hospital
HIPEC
Are You in a Poor Country; HIPEC is Still in Reach
Peritoneal carcinomatosis (PC) is a well-known sequel of multiple abdominal malignancies either arising from the gastro-intestinal tract or of gynaecologic origin.
- Trial name
- NCT04664218
- Testing
- HIPEC device
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Ovarian Cancer, Epithelial Ovarian Cancer
A Randomized Prospective Trail of HIPEC in Recurrent Ovarian Cancer Patients With HRR Mutation
A phase III prospective study with the primary objective to investigate the benefit of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in ovarian cancer patients with mutations in homologous recombination repair (HRR) genes.
- Conditions
- Ovarian Cancer, Epithelial Ovarian Cancer, Ovarian Cancer, Epithelial, Hyperthermic Intraperitoneal Chemotherapy(HIPEC)
- Trial name
- NCT04473339
- Testing
- CRS+HIPEC, CRS alone
- Where
- China
- Volunteers
- 280 people
- Sponsor
- CAI Hongbing
Ovarian Cancer, Ovary Neoplasm
Cytoreductive Surgery(CRS) Plus Hyperthermic Intraperitoneal Chemotherapy(HIPEC) With Lobaplatin in Advanced and Recurrent Epithelial Ovarian Cancer
A phase III prospective study with the primary objective to compare the efficacy and safety of HIPEC( Hyperthermic Intraperitoneal Chemotherapy).
- Conditions
- Ovarian Cancer, Ovary Neoplasm, Ovarian Neoplasms, Epithelial Ovarian Cancer
- Trial name
- HIPECOV (NCT03371693)
- Testing
- HIPEC, CRS, IVCT
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Zhongnan Hospital
Ovarian Cancer, HIPEC
HIPEC in Ovarian Cancer, Case-Controls Study With 10-years Follow up
Objectives: Compare overall survival (OS) and progression-free survival (PFS) among ovarian cancer patients who underwent into cytoreduction and HIPEC procedure vs patients who only received systemic chemotherapy in a 10-years…
- Trial name
- NCT04234243
- Testing
- cytoreduction and HIPEC
- Volunteers
- 144 people
- Sponsor
- Instituto de Seguridad Social del Estado de Mexico y Municipios
Gastric Cancer, Peritoneal Carcinomatosis
Cytoreductive Surgery and Intraperitoneal Chemotherapy for Stomach CAncer: a Feasibility Study
Rationale: For patients with peritoneal metastases of gastric origin, there is no consensus on the optimal treatment strategy. Several Asian and Western studies demonstrated hyperthermic intraperitoneal chemotherapy (HIPEC) and…
- Conditions
- Gastric Cancer, Peritoneal Carcinomatosis, HIPEC
- Trial name
- CISCA (NCT03150628)
- Testing
- Perioperative chemotherapy, Cytoreduction, HIPEC
- Where
- Netherlands
- Volunteers
- 3 people
- Sponsor
- Richard van Hillegersberg