Clinical trials: HIV Infections, completed
Human Immunodeficiency Virus (HIV), Acquired Immune Deficiency Syndrome (AIDS)
Pediatric Enhanced Surveillance Study
The Pediatric Enhanced Surveillance Study is a three part study of HIV-infected infants and children in South Africa to examine, clinical, immunologic, virologic, metabolic, psychosocial and behavioral outcomes.
- Trial name
- PESS (NCT02043769)
- Where
- 5 sites in South Africa
- Volunteers
- 396 people
- Sponsor
- Columbia University
HIV
Trial of Vitamin D in HIV Progression, Birth Outcomes, and Child Health
The purpose of this study to assess the effect of maternal vitamin D3 (cholecalciferol) supplementation on maternal HIV progression, small-for-gestational age infants, and infant stunting at 12 months postpartum for HIV-infected…
- Trial name
- ToV5 (NCT02305927)
- Testing
- Vitamin D3 (cholecalciferol)
- Where
- Tanzania
- Volunteers
- 2,300 people
- Sponsor
- Wafaie Fawzi
HIV Infections
Switching HIV-1 Infected Subjects From a Highly Active Anti-Retroviral Treatment (HAART) Regimen Dosed Twice Daily or More Frequently to a Once-Daily Regimen
The purpose of this study is to demonstrate that virologically controlled HIV-infected individuals can successfully switch from a standard-of-care regimen dosed twice-daily or more frequently to a simpler once-daily (QD) regimen…
- Trial name
- NCT00135369
- Testing
- stavudine extended-release, lamivudine, efavirenz
- Where
- 47 sites in United States, Puerto Rico
- Volunteers
- 300 people
- Sponsor
- Bristol-Myers Squibb
Influenza, HIV Infections
Immunogenicity of Novel H1N1 Vaccination Among HIV-Infected Compared to HIV-Uninfected Persons
The purpose of this research is to determine the effectiveness of the novel H1Nl influenza (inactivated/killed formulation) vaccine among both HIV-infected and HIV-uninfected persons.
- Trial name
- NCT00996970
- Where
- 3 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Dyslipidemia
A 12-Week Study Comparing Pitavastatin 4 mg vs. Pravastatin 40 mg in HIV-Infected Subjects
A 12-Week, Randomized, Double-Blind, Active-Controlled, Parallel-Group Study.
- Trial name
- NCT01301066
- Testing
- Pitavastatin, Pravastatin
- Where
- 35 sites in United States
- Volunteers
- 252 people
- Sponsor
- Kowa Research Institute, Inc.
Medication Adherence, HIV
Examining HIV Treatment Adherence During Early Disease
Determine the level, patterns, and correlates of objectively measured ART adherence in early and advanced-stage disease, among pregnant and non-pregnant individuals, to determine the need and nature of interventions to support…
- Trial name
- META (NCT02419066)
- Where
- 2 sites in South Africa, Uganda
- Volunteers
- 904 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
HIV-1-infection
Combining TLR9 Agonist With bNAbs for Reservoir Reduction and Immunological Control of HIV
This study is designed to evaluate the safety and efficacy of lefitolimod and 3BNC117/10-1074 in HIV-1-infected individuals on ART and during ATI as intervention to reduce the HIV-1 reservoir
- Trial name
- TITAN (NCT03837756)
- Testing
- Saline, Lefitolimod, 3BNC117 and 10-1074
- Where
- 8 sites in United States, Australia and 2 more
- Volunteers
- 47 people
- Sponsor
- University of Aarhus
HIV, Pregnancy
Implementing a Comprehensive Prevention of Mother-to-Child Transmission of HIV Program for South African Couples
This study will test the effectiveness of a behavioral intervention to increase Prevention of Mother-to-Child Transmission of HIV (PMTCT) protocol uptake among South African HIV positive pregnant women.
- Trial name
- NCT02085356
- Testing
- Protect your family
- Where
- South Africa
- Volunteers
- 1,967 people
- Sponsor
- University of Miami
HIV Positive, HIV Negative
India HIV-CervCa Project
The investigators propose to prospectively study the difference in treatment (CTRT) completion and toxicities between HIV positive and HIV negative women in India with locally advanced cervical cancer receiving CTRT.
- Conditions
- HIV Positive, HIV Negative, Cervical Cancer
- Trial name
- NCT07167069
- Testing
- Radiation Therapy
- Where
- India
- Volunteers
- 180 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
HIV Infections
A Phase I Multicenter Study of the Safety and Immunogenicity of MN rgp120/HIV-1 Vaccine Given Either Alone or in Combination With IIIB rgp120/HIV-1 Vaccine in Healthy Adult Subjects (NOTE: Original Study Extended ONLY for Patients Previously Enrolled on VEU 009)
AMENDED 10/1/93: To evaluate the influence of prior immunization with an rgp120 vaccine on immune response to a subsequent immunization with a different strain of rgp120 (VEU 009X extension - in patients previously enrolled on…
- Trial name
- NCT00001021
- Testing
- rgp120/HIV-1IIIB, rgp120/HIV-1MN
- Where
- 3 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy Aging
Preventing Chronic Disease: ActuaYa
The purpose of the study is to help older Hispanic women to increase physical activity, reach a healthy body weight, increase self-esteem and mood and increase knowledge about chronic diseases such as hypertension, diabetes, and…
- Trial name
- NCT04088552
- Testing
- Go4Life-Physical Activity/Exercise Program "Workout to Go" 5, ActuaYa Educational Sessions
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Miami
HIV/AIDS, Cervical Dysplasia
Factors Predicting Persistence of Oncogenic HPV and Cervical Dysplasia in HIV Infected Kenyan Women
This study will utilize a longitudinal study design to better understand the natural history of oncogenic Human Papillomavirus (HPV) infections in Human Immunodeficiency Virus (HIV)-infected and HIV-uninfected Kenyan women…
- Conditions
- HIV/AIDS, Cervical Dysplasia, HIV Infections
- Trial name
- NCT04045652
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 223 people
- Sponsor
- Indiana University
Sexual Behavior
Development of a Novel HIV Risk Reduction Intervention for Abused Women
The purpose of this study is to develop and evaluate an HIV risk reduction intervention for women with a history of abuse.
- Trial name
- NCT02118948
- Testing
- Abuse-focused intervention, Sexual behavior-focused intervention
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- The Miriam Hospital
HIV Infections
Antiviral Activity of and Resistance to Lamivudine in Combination With Zidovudine, Stavudine, or Didanosine
To evaluate the efficacy, safety, and pharmacokinetics of lamivudine (3TC) combined with zidovudine (AZT), stavudine (d4T), or didanosine (ddI) in comparison with d4T or ddI monotherapy in HIV-infected patients with no prior…
- Trial name
- NCT00000838
- Testing
- Lamivudine, Stavudine, Zidovudine
- Where
- 32 sites in United States, Puerto Rico
- Volunteers
- 256 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Opioid Dependence
Methadone Maintenance & HIV Risk in Ukraine
Treatment of opioid dependence is an important way to reduce the spread of HIV and other infectious diseases, particularly in Ukraine since intravenous opioid use is the major way these infections are being spread.
- Trial name
- NCT00351026
- Testing
- Methadone
- Where
- 2 sites in Ukraine
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
HIV Infections, Sexually Transmitted Diseases
Peer Intervention Latino Immigrant MSM
This study evaluates a peer intervention with HIV/STI self-testing kits to increase HIV/STI testing and PrEP uptake among Latino immigrant men who have sex with men.
- Trial name
- NCT03922126
- Testing
- Peer counseling, HIV/STI self-testing kits
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV-Infection
Immediate Versus Deferred Antiretroviral Therapy in HIV-infected Patients Presenting With Acute AIDS-defining Events
The purpose of this study is to compare the early versus deferred initiation of antiretroviral combination therapy consisting of tenofovir, emtricitabine and atazanavir/ritonavir in treatment naive patients who present with an…
- Trial name
- IDEAL (NCT01417949)
- Testing
- Time of starting antiretroviral therapy
- Where
- 17 sites in Germany
- Volunteers
- 61 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Hiv, Minority Stress
Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM - Aim 3
The overall aim of the research study is to develop and test a mindfulness-based program for young adult gay, bisexual, and queer men at risk for HIV (Brown University IRB approved protocol #2004002698).
- Conditions
- Hiv, Minority Stress, Mental Health Wellness 1
- Trial name
- MBQR (NCT05855655)
- Testing
- Mindfulness-Based Queer Resilience (MBQR)
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Brown University
HIV Infections
Administration of Growth Hormone to Increase CD4+ Count in Patients Taking Anti-HIV Drugs
This study is designed to evaluate the ability of growth hormone (GH, also known as somatropin) to increase CD4+ cell counts in patients taking anti-HIV drugs.
- Trial name
- NCT00050921
- Testing
- somatropin, Hepatitis A virus, inactivated, Keyhole-Limpet Hemocyanin
- Where
- 13 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hepatitis C, HIV Infections
Coaching for HCV and HIV
The objective of this study is to determine the feasibility and acceptability of a peer recovery coach (PRC) intervention to improve linkage to hepatitis C (HCV) and/or human immunodeficiency virus (HIV) care, treatment…
- Conditions
- Hepatitis C, HIV Infections, Opioid-use Disorder
- Trial name
- NCT04314414
- Testing
- PRC brief motivational interview intervention, Phone contact
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Boston Medical Center
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