Clinical trials: HIV Medication Adherence
HIV Infections
Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings
This study compared 3 different three-drug combinations in HIV infected individuals starting their first HIV treatment regimens.
- Trial name
- PEARLS (NCT00084136)
- Testing
- Atazanavir, Didanosine (enteric-coated), Efavirenz
- Where
- 42 sites in United States, Brazil and 7 more
- Volunteers
- 1,571 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
HIV Prevention, HIV Risk
Evaluating an Interactive Digital Toolkit for Women's PrEP Implementation
The goal of this study is to test if a Digital PrEP Toolkit helps cisgender women learn about and access PrEP in Alabama and Mississippi. PrEP is a medication that prevents HIV infection.
- Conditions
- HIV Prevention, HIV Risk, Sexual and Reproductive Health
- Trial name
- NCT07292584
- Testing
- Interactive Digital PrEP Toolkit
- Where
- 4 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Human Immunodeficiency Virus (HIV), Acquired Immunodeficiency Syndrome (AIDS)
Evaluating Rewards-Based Adherence and Electronic Medication Monitoring in HIV-Positive Adolescents
The primary objective of this project is to assess the study population's acceptance of two medication adherence support strategies: incentive-based programs and electronic medication monitoring.
- Trial name
- NCT01849393
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- St. Jude Children's Research Hospital
HIV Infections, AIDS
Antiretroviral Adherence and Drug-level Monitoring
This observational study aims to investigate medication adherence and drug-level monitoring of antiretroviral agents in a cohort of people living with HIV in Indonesia.
- Conditions
- HIV Infections, AIDS, Antiretroviral Therapy, Highly Active, Adherence, Medication
- Trial name
- NCT05996094
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Zamrotul Izzah
Medication Adherence
Nurse Delivered Cell Phone Adherence Intervention (Pick It UP)
Persistent adherence to antiretroviral therapy is necessary for the successful treatment of HIV infection. The proposed research will test a theory-based behavioral intervention that includes objectively monitoring HIV treatment…
- Trial name
- PIU (NCT01359280)
- Testing
- Adherence Counseling, General Health Counseling, Text Messages
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of Connecticut
HIV Infections
A Study of Two Anti-HIV Drug Combinations
The purpose of this study is to compare the safety and effectiveness of taking lamivudine (3TC) plus zidovudine (ZDV) plus a protease inhibitor (PI) with taking the 3TC/ZDV combination tablet (Combivir) plus a PI.
- Trial name
- NCT00002203
- Testing
- Lamivudine/Zidovudine, Lamivudine, Zidovudine
- Where
- 7 sites in United States, Puerto Rico
- Sponsor
- Glaxo Wellcome
HIV Infections
Implementation and Assessment of a Medication Therapy Management Program in HIV Patients at High Risk of Adverse Drug Events at Khartoum, Sudan
This clinical trial aims to evaluate the effectiveness and cost-effectiveness of two levels of a pharmacist-led Medication Therapy Management (MTM) program, Basic MTM and Enhanced MTM, compared with usual care for HIV patients at…
- Trial name
- HIV-MTM-SUDAN- (NCT07750834)
- Testing
- Basic MTM, Enhanced MTM
- Where
- Sudan
- Volunteers
- 1,149 people
- Sponsor
- Universiti Sains Malaysia
HIV Infection
Evaluation of Behavioral Intervention for HIV Positive Prisoners in NC and TX
Purpose: The purpose of this study is to determine if a comprehensive intervention supporting seek-test-and-treat results in a significant reduction in the potential for HIV-infected prisoners to transmit their virus after…
- Trial name
- imPACT (NCT01629316)
- Testing
- Text reminders, counseling, and link coordination, Standard of care - control arm
- Where
- 2 sites in United States
- Volunteers
- 381 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV
Striving Towards EmPowerment and Medication Adherence (STEP-AD)
Striving Towards Empowerment and Medication Adherence (STEP-AD) is a research study aimed at developing an intervention for Black women living with HIV to address psychosocial factors (i.e.
- Trial name
- STEP-AD (NCT02764853)
- Testing
- Experimental Intervention (STEP-AD), Enhanced Treatment as Usual (E-TAU)
- Where
- 2 sites in United States
- Volunteers
- 184 people
- Sponsor
- University of Miami
HIV/AIDS, Medication Adherence
Measuring and Monitoring Adherence to ART With Pill Ingestible Sensor System
Introduction of antiretroviral therapy (ART) has transformed HIV-infection from a fatal to manageable disease but adherence to ART remains critical to optimize outcomes.
- Trial name
- NCT02797262
- Testing
- Proteus digital health feedback (PDHF) system
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of California, Los Angeles
HIV
Comparing the Effectiveness of Two Alcohol+Adherence Interventions for HIV+ Youth
Alcohol use among persons with HIV exacerbates health problems and accelerates HIV disease progression. Antiretroviral therapy (ART) is the single most important treatment for people living with HIV.
- Trial name
- NCT01969461
- Testing
- Motivational Enhancement Therapy (MET)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Wayne State University
HIV
A Technology-Delivered Peer-to-Peer Support ART Adherence Intervention for Substance-using HIV+ Adults
The "Thrive With Me" (TWM) trial is testing the efficacy of a mobile enhanced website aimed at improving Antiretroviral Therapy (ART) adherence for HIV-positive men who have sex with men (MSM).
- Trial name
- TWM (NCT02704208)
- Testing
- Thrive With Me Control, Thrive With Me Intervention
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- University of Minnesota
HIV Infections
Handheld Computers to Improve Adherence to Anti-HIV Drug Regimens
While anti-HIV drugs can significantly reduce viral loads, the medication regimens can be complex, and patients must take them correctly for the best effect. Nonadherent patients risk developing drug resistant HIV strains.
- Trial name
- NCT00053443
- Testing
- Medication Reminder System/Adherence Tracker
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hepatitis C, Chronic, HIV Infection
ADHEPTA Study: Adherence Questionnaire in Hepatitis C
Main objective: To study and validate a questionnaire measuring treatment adherence in patients with Hepatitis C virus (HCV) infection.
- Trial name
- ADHEPTA (NCT00998621)
- Testing
- Adherence questionnaire
- Where
- Spain
- Volunteers
- 1,120 people
- Sponsor
- Fundacion IMIM
HIV
Managerial Database II
This study will collect information on health status and risk behaviors, as well as basic demographic and biomedical information for a group of HIV positive adolescents receiving care at the ATN sites.
- Trial name
- NCT01009827
- Testing
- Observation
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 1,712 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV, Drug Use Disorders
HEART to HAART: Smartphone Intervention to Improve HAART Adherence for Drug Users
HIV infected drug users have greater difficulty adhering to highly active antiretroviral therapy compared to non-drug users. As sustained adherence to highly active antiretroviral therapy is critical to reducing HIV related…
- Trial name
- NCT01413529
- Testing
- HEART to HAART, adherence counseling with the addition of smartphone control
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Maryland, Baltimore
Adherence, Medication, Risk Behavior
DOT Diary Optimization Pilot: A Pilot Study to Optimize the DOT Diary App to Measure PrEP Adherence
The researchers are working with a technology company, AiCure, to develop a smartphone app, DOT Diary, which combines two drug adherence strategies.
- Conditions
- Adherence, Medication, Risk Behavior, Pre-Exposure Prophylaxis, HIV Prevention
- Trial name
- NCT03387462
- Testing
- Emtricitabine / Tenofovir Disoproxil Oral Tablet, DOT Diary mobile app
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
AIDS, HIV Infections
Social-Psychological Intervention to Improve Adherence to HAART
All eligible patients will be invited to use electronic monitoring of medication (MEMS) during the next six months. After two months with MEMS the enrolled patients will be randomized to intervention group or to control group.
- Trial name
- SPIAH-Q (NCT00716040)
- Testing
- Social-psycho intervention to improve adherence to HAART, Usual care
- Where
- Brazil
- Volunteers
- 121 people
- Sponsor
- University of Sao Paulo
Patient Commitment Preferences for Medication Adherence
Understanding Medication Adherence Among HIV Patients
In anticipation of a pilot study incorporating behavioral economics into the treatment of infectious diseases, we will conduct a survey with HIV/AIDS patients at the Ponce Clinic (Infectious Disease Program of Grady Memorial…
- Trial name
- NCT01305590
- Testing
- Survey to Understand Medication Adherence among HIV Patients
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Bureau of Economic Research, Inc.
HIV/AIDS, Adherence, Medication
Quantification of Tenofovir Alafenamide Adherence (QUANTI-TAF)
This study is being done to evaluate the relationship between adherence to antiretroviral therapy (ART) and HIV drug concentrations in persons living with HIV (PLWH) that are taking tenofovir alafenamide (TAF).
- Trial name
- NCT04065347
- Testing
- Digital Pill
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Colorado, Denver