Clinical trials: HIV Medication Adherence
HIV Infections, Sexually Transmitted Diseases
Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention
The purpose of this study is to compare the effectiveness of two mobile health technologies (text messaging or a mobile app) designed to help people take HIV pre-exposure prophylaxis (PrEP) as directed by the clinic.
- Trial name
- PCORI PrEP (NCT04855773)
- Testing
- PrEPmate, Dot Diary
- Where
- 4 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
HIV/AIDS, Adolescent Behavior
Youth Power Action Feasibility Study of Online Support Group Intervention Among Adolescents Living With HIV in Nigeria
This study will examine the feasibility and acceptability of an intervention designed to improve retention in HIV care services and improve anti-retroviral therapy (ART) adherence among adolescents ages 15-19 years living with…
- Conditions
- HIV/AIDS, Adolescent Behavior, Medication Adherence, Health Behavior
- Trial name
- NCT03076996
- Testing
- Online support group
- Where
- Nigeria
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- FHI 360
Medication Adherence, HIV
Development of a Urine-Based Point-of-Care Test for Adherence to Antiretroviral Drugs
This is a single-center, open label study to identify adherence levels of commonly prescribed FDA-approved antiretroviral agents by tracking the decline of drug concentrations in plasma, urine and saliva following abrupt drug…
- Trial name
- APTAMER (NCT04302896)
- Testing
- dolutegravir oral tablet 50mg, emtricitabine/tenofovir alafenamide oral tablet 200mg/25mg, tenofovir disoproxil fumarate oral tablet 300mg
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rhonda Brand
HIV Infections, Substance Use Disorders
Couples ART Adherence Intervention for PWID in Kazakhstan
The fastest growing HIV epidemics globally are driven by injection drug use, but only a small percentage of HIV-positive people who inject drugs (PWID) have achieved viral suppression.
- Trial name
- NCT03555396
- Testing
- SMART Couples 2, Standard of Care
- Where
- Kazakhstan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV
The Tailored-Motivational Interviewing Project
The purpose of the Tailored Motivational Interviewing Project (TMI) is to develop an implementation intervention to increase evidence-based patient-provider communication strategies using a Motivational Interviewing (MI)…
- Trial name
- TMI Project (NCT03181022)
- Testing
- Motivational Interviewing
- Where
- 2 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Preventive Medicine, HIV Infections
Retention in PrEP Care for African American MSM in Mississippi
Innovative and novel HIV prevention interventions are urgently needed for African American (AA) young men who have sex with men (YMSM) in the South, and in Mississippi in particular.
- Trial name
- NCT03256435
- Testing
- RAMP PrEP initiation, adherence, and retention intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Brown University
HIV/AIDS, Adherence, Medication
Project ADHERE: Clinical Proof-of-Concept of a Tenofovir (TFV) Aptamer-Based Biosensor
Truvada®, an oral pill comprised of two anti-retroviral compounds, emtricitabine (FTC) and tenofovir disoproxil fumarate (TDF), is currently the only drug combination approved for pre-exposure prophylaxis (PrEP) in women exposed…
- Conditions
- HIV/AIDS, Adherence, Medication, Drug Use
- Trial name
- NCT04870671
- Testing
- Tenofovir Disoproxil Fumarate/Emtricitabine (TDF/FTC)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
HIV Infections
Triggered Escalating Real-time Adherence (TERA) Intervention
Youth Living with HIV (YLWH) often face unique challenges achieving high and sustained rates of adherence to their antiretroviral therapy (ART).
- Trial name
- TERA (NCT03292432)
- Testing
- TERA Intervention (TERA), Standard of Care (SOC)
- Where
- 8 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV/AIDS, HIV Infections
Harm Reduction Program For Informal PrEP Users In A Community-based Setting (seguiPrEP)
Pre-Exposure Prophylaxis (PrEP) is a biomedical strategy consisting of the use of antiretroviral therapy by HIV-seronegative people at high risk of acquiring HIV, to prevent the infection.
- Conditions
- HIV/AIDS, HIV Infections, Sexually Transmitted Diseases, Vaccination
- Trial name
- seguiPrEP (NCT03996941)
- Testing
- Harm reduction of informal PrEP use, PrEP follow up based on point of care testing
- Where
- Spain
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- BCN Checkpoint
HIV
Mental Health and Medication Adherence Among MSM in South Africa
The goal of this behavioral study is to improve psychological well-being and optimization of HIV prevention and care outcomes for Men who have sex with men (MSM) in South Africa.
- Trial name
- NCT06880172
- Testing
- WeCare
- Where
- South Africa
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University