Clinical trials: HIV Risk
Human Immunodeficiency Virus Infection
Mechanisms of Immune Reconstitution & Reduced Immune Activation Following Darunavir-based ART
Potent HIV suppression with Darunavir-based antiretroviral therapy (ART) will lead to repopulation of gastrointestinal-associated lymphoid tissue (GALT) cluster of differentiation (CD)4+ T-cell populations, normalization of…
- Trial name
- NCT01869634
- Testing
- darunavir with ritonavir and fixed-dose viread+emtricitabine daily
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
HIV/AIDS
Social Media HIV Prevention Intervention for High Risk Rural Women
The overall aim of this R34 application is to adapt and feasibility test an evidence-based HIV prevention education for high-risk, underserved rural women in Appalachia.
- Trial name
- NCT03456453
- Testing
- NIDA Standard for HIV Prevention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Michele Staton
Intimate Partner Violence, HIV
The SASA! Study: An Evaluation of a Community Intervention to Address Gender-based Violence and Reduce HIV/AIDS Risk in Uganda
The SASA! Study is a cluster randomized trial of a community mobilization intervention for the prevention of HIV and gender based violence. The study is being conducted in Kampala, Uganda.
- Trial name
- SASA! (NCT00790959)
- Testing
- SASA!, Control
- Where
- Uganda
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Hiv, HIV Infections
Personalized Prevention for Couples: A 16-month Digital RCT
This couples-based, digital health intervention project is serostatus neutral and seeks to determine efficacy for: a) use and adherence to evidence-based HIV/STI prevention-care strategies; b) creation and adherence to a tailored…
- Conditions
- Hiv, HIV Infections, Sexually Transmitted Infection, Sexually Transmitted Diseases
- Trial name
- LuvHub (NCT05708014)
- Testing
- Intervention LuvHub, Waitlist Control LuvHub
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- Florida International University
HIV Infections, Herpes Genitalis
HIV and Genital Herpes Among High-Risk Men Who Have Sex With Men (MSM) in Lima, Peru
The purpose of this study is to provide biomedical and behavioral information that is necessary for planning and starting HIV prevention trials in Lima, Peru.
- Conditions
- HIV Infections, Herpes Genitalis, HIV Seronegativity, Syphilis
- Trial name
- NCT00023582
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
A Phase I Study of Modified Vaccinia Virus Ankara (MVA-B) in Healthy Volunteers at Low Risk of HIV Infection
The purpose of this clinical trial is to study a modified pox viral vector considering: 1. HIV subtype B accounts for the most frequent virus strain in Europe and North America, as well as in many parts of the world. 2.
- Trial name
- RisVac02 (NCT00679497)
- Testing
- MVA-B
- Where
- 2 sites in Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Juan A. Arnaiz
HIV Infections
Long-term Follow-up of Long-acting Cabotegravir (CAB LA) for PrEP (Pre-exposure Prophylaxis) in Participants at Risk of Acquiring HIV (Human Immunodeficiency Virus)
The purpose of this study is long-term evaluation of long-acting injectable cabotegravir (CAB LA) for HIV pre-exposure prophylaxis (PrEP) in eligible participants who have completed DAIDS (Division of AIDS) sponsored studies HPTN…
- Trial name
- PALISADE (NCT06134362)
- Testing
- CAB LA
- Where
- 33 sites in Argentina, Botswana and 10 more
- Volunteers
- 2,998 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
HIV Infections
Male Partner Involvement in the Prevention of MTCT of HIV
The study aims to invite male sexual partners to attend antenatal clinic with their pregnant partners to either acquire pregnancy information or undergo voluntary counselling and testing for HIV.
- Trial name
- NCT00405990
- Testing
- Voluntary counselling and HIV testing in ANC for PMTCT, VCT
- Where
- South Africa
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London
HIV Infections, Alcohol Abuse
Brief Electronic Intervention for Heavy Drinking and Sex Risk Among MSM Seeking HIV Testing
The overall objective of this research is to use both qualitative and quantitative data to inform the development of a technology-based intervention for heavy drinking and sexual risk behavior among men who have sex with men…
- Trial name
- NCT03435783
- Testing
- Brief Electronic Intervention, Attention-Matched Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brown University
HIV, HIV Infections
Internet-based HIV/STI Prevention for Young MSM Receiving HIV Testing
The purpose of this study is to develop an empirically validated, scientifically-based HIV and STI prevention program that can be delivered online to young men who have sex with men (YMSM) who were recently tested for HIV.
- Trial name
- KIU (NCT00968188)
- Testing
- Keep It Up!, Information only
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
HIV, Acquired Immunodeficiency Syndrome
A Unified Intervention for Young Gay and Bisexual Men's Minority Stress, Mental Health, and HIV Risk
The intent of the proposed randomized controlled trial is to test the efficacy of a principle-based, transdiagnostic cognitive behavioral therapy (CBT) intervention that addresses the pathways through which minority stress…
- Trial name
- NCT02929069
- Testing
- ESTEEM, CMHT, VCT
- Where
- 2 sites in United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Yale University
Hiv
TelePrEP for At-risk Youth in Colorado
Youth represent the largest proportion of new HIV infections in Colorado, reflective of their inadequate access and uptake of pre-exposure prophylaxis(PrEP)for HIV prevention.
- Trial name
- NCT05520905
- Testing
- TelePrEP
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
HIV Infections
Hormonal Birth Control and the Risk of Acquiring HIV
The purpose of this study is to find out whether hormonal birth control increases, decreases, or does not change the risk of women becoming infected with HIV.
- Trial name
- NCT00006324
- Testing
- Ethinyl estradiol/levonorgestrel, Medroxyprogesterone acetate
- Where
- United States
- Volunteers
- 6,360 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
HIV Infections, HIV Prevention and Care
HealthMpowerment Korea: Pilot Testing the Cultural Adaptation of a Digital HIV Intervention for Men Who Have Sex With Men in South Korea
This study tests a mobile application (app) designed to support sexual health and prevent human immunodeficiency virus (HIV) among young men in South Korea.
- Conditions
- HIV Infections, HIV Prevention and Care, Risk Reduction Behavior, Digital Health
- Trial name
- HMP Korea (NCT07741123)
- Testing
- Bandi Mobile Application (Full Access), Information-Only Mobile Application (Limited Access)
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Seul Ki Choi
HIV/AIDS
Acceptability, Feasibility and Preliminary Impact of OurPlan, an mHealth HIV Prevention Intervention for Male Couples
The study will evaluate the use and preliminary impact of an mHealth app for improving sexual health outcome measures among male couples by assessing whether exposure and use of the app results in improvements in participants and…
- Trial name
- OurPlan (NCT04836091)
- Testing
- Waitlist, Intervention
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Florida International University
Health Knowledge, Attitudes, Practice, Health Risk Behaviors
Like Father Like Son
This purpose of this study is to look at the best way to offer the Like Father Like Son + Spear \& Shield program.
- Trial name
- NCT04119414
- Testing
- Spear and Shield (S&S) Program, Like Father Like Son (LFLS) Program
- Where
- Zambia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cardiovasculars Risk Factors, Heart Failure
Adapted Physical Activity and Prevention of Cardiovascular Risk in Elderly People Living With HIV:Comparative Study
A quasi-experimental and comparative study will be conducted in two different geographical areas (Europe-France and Africa-Cameroon) on a period of 18 months.
- Trial name
- NCT05201417
- Testing
- adapted physical activity
- Where
- 3 sites in Cameroon, France
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Support and Education Technic Centre
Substance Abuse, HIV
Electronic SBI(RT) for MSM in Argentina
The main goal of this pilot randomized controlled trial (RCT) with 200 participants is to establish the processes and procedures for a subsequent large-scale efficacy trial of an electronic-Screening, Brief Intervention, Referral…
- Trial name
- NCT05542914
- Testing
- electronic screening and brief intervention., Phase 2: Assessment Only
- Where
- Argentina
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Florida State University
HIV Infections
No Excuses/Sin Buscar Excusas Intervention to Reduce Latino Men's HIV Risks
The overall goal of this study is to develop and evaluate a brief, video-based, group-level intervention designed to reduce sexual risk taking among culturally diverse English- and Spanish-speaking Latino men who have sex with…
- Trial name
- NCT00690690
- Testing
- Video (group-delivered video-based intervention), HCT
- Where
- United States
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV Prevention, Conception
Safer Conception for Women - Understanding Use of Periconception PrEP
Women who choose to conceive with an infected or unknown serostatus partner in HIV-endemic settings need prevention strategies to reduce periconception HIV acquisition risk.
- Trial name
- NCT03194308
- Testing
- PrEP for Safer Conception
- Where
- South Africa
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital