Clinical trials: HIV Treatment Adherence
HIV Infections
The Effect of Teaching HIV-Infected Patients About HIV and Treatment
The purpose of this study is to see if an HIV-education course can help under-represented, HIV-infected patients. This study examines the areas of faithfulness to drug regimen, level of HIV in the blood, and health status.
- Trial name
- NCT00002409
- Testing
- Lamivudine/Zidovudine, Abacavir sulfate
- Where
- 25 sites in United States
- Volunteers
- 200 people
- Sponsor
- Glaxo Wellcome
HIV
Youth mHealth Adherence Intervention for HIV+ YMSM
This study will help determine feasibility, acceptability, and preliminary efficacy of an app for HIV medication adherence over a 3-month period.
- Trial name
- NCT03092115
- Testing
- HIV medication adherence app
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
HIV Infections
Impact of Peer Health Workers and Mobile Phones on HIV Care
The provision of antiretroviral therapy (ART) in rural, resource-limited settings entails substantial challenges due to limitations in the health service infrastructure and in human resources for HIV/AIDS care.
- Trial name
- NCT00675389
- Testing
- Peer Health Workers Intervention, Peer Health Workers and Mobile Phone Intervention
- Volunteers
- 1,200 people
- Sponsor
- Johns Hopkins University
HIV Infections, Insomnia
The Treatment of Insomnia in Patients With HIV Disease
This study is designed to evaluate the efficacy of two commonly prescribed sleep aids for use in patients who are HIV positive and suffer from insomnia.
- Trial name
- NCT00465972
- Testing
- Doxepin, Temazepam
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Duke University
HIV Infections
Therapeutic Drug Monitoring and Viral Resistance Testing in the Treatment of HIV-Infected Children
This study will evaluate a new treatment strategy called therapeutic drug monitoring (TDM) in HIV-infected children and adolescents.
- Trial name
- NCT00032669
- Testing
- HAART
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Cancer Institute (NCI)
Medication Adherence, HIV Prevention
Single Dose Truvada Study
This study examines tenofovir (TFV) drug concentrations in adults one day after taking a single dose of Truvada® - a pill used to prevent and treat HIV infection.
- Trial name
- NCT03719053
- Testing
- Tenofovir
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
HIV
Uptake and Adherence to Daily Oral PrEP as a Primary Prevention Strategy for Young African Women: A Vanguard Study
To assess the acceptance rate, adherence, acceptability, and continuation of oral pre-exposure prophylaxis (PrEP) among young southern African women.
- Trial name
- NCT02732730
- Testing
- Truvada, Drug level counseling at Weeks 8 and 13
- Where
- 3 sites in South Africa, Zimbabwe
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- HIV Prevention Trials Network
HIV
Community-based Interventions to Increase HIV Testing and HIV Care Utilization
The purpose of this study is to conduct a cross-site evaluation of the Kaiser Permanente's Community-based Interventions to Increase HIV Testing and HIV Care Utilization Program, designed to support community-based interventions…
- Trial name
- NCT01867177
- Testing
- HIV testing, standard of HIV care, HIV care utilization
- Where
- United States
- Volunteers
- 583 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
HIV, HIV Infections
Measurement of Adherence to ART in HIV-Infected Children in Uganda (The CHARTA Study)
This study will compare methods of determining whether HIV-infected children take their medications.
- Trial name
- NCT00868257
- Where
- Uganda
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Patient Satisfaction, Patient Preference
Switch From Oral Therapy to Long-acting Injectable Cabotegravir + Rilpivirine
This protocol will assess the level of satisfaction, acceptance of treatment and quality of life of patients with undetectable HIV who voluntarily change from oral to injectable antiretroviral treatment at 72 weeks of follow-up.
- Conditions
- Patient Satisfaction, Patient Preference, Quality of Life, Acceptability of Health Care
- Trial name
- CABO-LA (NCT05835635)
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- Pontificia Universidad Catolica de Chile
HIV
Integrating Supports to Promote PrEP for Black Adolescents Working With Apps- Alabama
This study applies Social Cognitive Theory to develop behavioral interventions promoting PrEP adherence. It seeks to adapt and test the enhanced HMP app for feasibility and acceptability among Black adolescents and young adults…
- Trial name
- NCT06876324
- Testing
- HealthMPowerment App
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV/AIDS
A Randomized Controlled Trial of an Antiretroviral Treatment Adherence Intervention for HIV+ African Americans
Project Rise is a randomized controlled trial (RCT) of an innovative, culturally congruent treatment education (TE) intervention for African Americans with HIV that targets cultural and social issues contributing to health…
- Trial name
- NCT03331978
- Testing
- Rise - Treatment Education
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- RAND
HIV/AIDS
Antiretroviral Adherence and Quality-of-life Support for HIV+ Patients in India With Twice-daily Interactive Voice Response (IVR) Calls With Health and Mental Health Messaging Compared to Weekly IVR Survey Only Control Condition: The Mobile-messaging Adherence and Support for Health Study, India.
The purpose of this study is to test whether twice-daily Interactive Voice Response (IVR) calls made at the estimated times of patients' antiretroviral (ART) medication dosing and three reminder calls for monthly clinic…
- Trial name
- MASHIndia (NCT02118454)
- Testing
- Daily IVR Calls Intervention, Weekly IVR Survey Only
- Where
- 2 sites in India
- Volunteers
- 400 people
- Sponsor
- University of California, Los Angeles
Hiv
Postpartum Adherence Clubs for Antiretroviral Therapy
South Africa is implementing the policy of universal initiation of lifelong antiretroviral therapy (ART) in all HIV-infected pregnant women regardless of CD4 cell count or disease stage ("Option B+").
- Trial name
- PACART (NCT03200054)
- Testing
- Adherence Clubs
- Where
- South Africa
- Volunteers
- 412 people
- Sponsor
- University of Cape Town
HIV
Evaluating a Youth-Focused Economic Empowerment Approach to HIV Treatment Adherence
The goal of Suubi+Adherence is to examine the impact and cost associated with an innovative intervention to increase adherence to HIV treatment for HIV-infected adolescents.
- Trial name
- NCT01790373
- Testing
- Suubi+Adherence, Bolstered Standard of Care
- Where
- 2 sites in United States, Uganda
- Volunteers
- 702 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
HIV/AIDS, HIV Infections
Harm Reduction Program For Informal PrEP Users In A Community-based Setting (seguiPrEP)
Pre-Exposure Prophylaxis (PrEP) is a biomedical strategy consisting of the use of antiretroviral therapy by HIV-seronegative people at high risk of acquiring HIV, to prevent the infection.
- Conditions
- HIV/AIDS, HIV Infections, Sexually Transmitted Diseases, Vaccination
- Trial name
- seguiPrEP (NCT03996941)
- Testing
- Harm reduction of informal PrEP use, PrEP follow up based on point of care testing
- Where
- Spain
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- BCN Checkpoint
HIV Infections
Home-based AIDS Care Project
The Home-based AIDS care program pilot project delivers and monitors antiretroviral (ARV) and tuberculosis (TB) medications at the homes of 1,000 people with HIV living in a rural area of Uganda.
- Trial name
- NCT00119093
- Testing
- Laboratory and clinical monitoring regimens
- Where
- Uganda
- Volunteers
- 1,000 people
- Sponsor
- Centers for Disease Control and Prevention
HIV Infections
HIV Treatment-Readiness Measure (HTRM) Validation
The goal of this study is to assess the reliability of the HIV Treatment Readiness Measure (HTRM) to assist clinicians in: (1) determining whether or not youth living with HIV are ready to initiate HAART and (2) identifying youth…
- Trial name
- NCT00686049
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 200 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV, HIV Treatment
Evaluating the Impact of Using the B-OK Bottles for HIV and ART Literacy in South Africa
Consistent use of antiretroviral therapy (ART) is essential for achieving suppression among people with HIV (PWH). Yet despite improvements in access to ART and improving viral suppression rates, an estimated one-third of PWH…
- Trial name
- NCT07703891
- Testing
- B-OK Bead Bottles Intervention (delivered in person), B-OK Bottles Intervention (delivered by video), Control
- Where
- South Africa
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Adherence, Medication, Risk Reduction
Prevention and Risk: Treatment With a New Emphasis on Relationships
This research examines the efficacy of an individually-delivered intervention tailored for YMSM in relationships. The intervention - termed PARTNER - utilizes a brief (4 session) motivational interviewing format to target…
- Conditions
- Adherence, Medication, Risk Reduction, Drug Use, Sex, Anal
- Trial name
- PARTNER (NCT03396367)
- Testing
- PARTNER, Education Intervention
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York