Clinical trials: HIV-infection/AIDS
Acquired Immunodeficiency Syndrome Virus, Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted
Score System for Prediction Risk and Early Diagnosis of HCC in HIV/HCV Patients
The aim of this study is to establish a clinical score panel based on clinical, molecular and genetic parameters that allow us to stratify and obtain an early detection of patients with an increased risk of developing…
- Conditions
- Acquired Immunodeficiency Syndrome Virus, Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted, Hepatocellular Carcinoma
- Trial name
- NCT02113865
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Hepatitis C, Hepatitis B
HBV/HCV/HIV in Belgian Prisons
To assess the prevalence of blood-borne viral infections in prisons in Belgium, screening will be executed in several prisons in Flanders, Brussels and Wallonia to obtain a geographical representative distribution.
- Conditions
- Hepatitis C, Hepatitis B, HIV Infections
- Trial name
- NCT04366492
- Testing
- Prevalence of blood borne viral infections (HBV/HCV/HIV)
- Where
- 2 sites in Belgium
- Volunteers
- 3,045 people, healthy volunteers welcome
- Sponsor
- Hasselt University
HIV Infections, Pneumocystis Pneumonia
Pneumocystis in Pathogenesis of HIV-associated Emphysema
A. Statement of Hypotheses: HIV-infected patients have an increased incidence of emphysema compared to non-HIV-infected smokers, and it has been hypothesized that this accelerated disease progression is the result of one or more…
- Conditions
- HIV Infections, Pneumocystis Pneumonia, Emphysema, Chronic Obstructive Pulmonary Disease
- Trial name
- PACT (NCT00869544)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Pittsburgh
HIV Infections
Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings
This study compared 3 different three-drug combinations in HIV infected individuals starting their first HIV treatment regimens.
- Trial name
- PEARLS (NCT00084136)
- Testing
- Atazanavir, Didanosine (enteric-coated), Efavirenz
- Where
- 42 sites in United States, Brazil and 7 more
- Volunteers
- 1,571 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
HIV, Latent Tuberculosis
Testing for Tuberculosis in the United Kingdom HIV Infected Population
Human Immunodeficiency Virus (HIV) is the strongest individual risk factor for the reactivation of tuberculosis (TB) after previous exposure to Mycobacterium tuberculosis (MTb).
- Trial name
- NCT02712671
- Testing
- Chest radiograph, Blood interferon gamma release assay, Tuberculin skin testing (TST)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- University College, London
HIV Infections
Reducing Post-Hospital Mortality in HIV-infected Adults in Tanzania
This research is being done to assess the efficacy of a case management intervention to improve the one year mortality rate of hospitalized, HIV-infected, Tanzanian adults.
- Trial name
- NCT03858998
- Testing
- Case Management Intervention, Control
- Where
- 16 sites in Tanzania
- Volunteers
- 500 people
- Sponsor
- Weill Medical College of Cornell University
Papillomavirus Vaccines, Human Immunodeficiency Virus
Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV
The primary objective of this study is to determine the magnitude and breadth of the serum antibody response to the nonavalent HPV vaccine (Gardasil-9) in adults with well-controlled HIV infection.
- Conditions
- Papillomavirus Vaccines, Human Immunodeficiency Virus, Papillomavirus Infection, Serology
- Trial name
- AGO-Gard (NCT05266898)
- Testing
- Human papillomavirus 9-valent vaccine, recombinant, human papillomavirus vaccine, recombinant
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Human Immunodeficiency Virus, Mental Disorder
Integrated Mental Health Care for Pregnant Women With HIV in Kenya: The Tunawiri Study
This study seeks to improve mental health, pregnancy, and HIV outcomes among pregnant and postpartum women living with HIV with common mental health disorders in Kenya.
- Trial name
- NCT06117163
- Testing
- Collaborative Care Model
- Where
- Kenya
- Volunteers
- 900 people
- Sponsor
- University of Colorado, Denver
HIV Infections
Study of HIV Patients With Undetectable Viral Load and Abnormal Lipids Switching to Atazanavir/Ritonavir
Patients with HIV who are virologically suppressed on a lopinavir/ritonavir combination highly active antiretroviral therapy (HAART) regimen but with elevated non-HDL cholesterol are randomized to remain on lopinavir/ritonavir or…
- Trial name
- NCT00120393
- Testing
- atazanavir/ritonavir +2 NRTIs (immediate Switch Group), LPV/r +2 NRTIs (Delayed/optional Switch Group)
- Where
- 14 sites in United States, Canada
- Volunteers
- 192 people
- Sponsor
- Bristol-Myers Squibb
Acute HIV Infection
Implementation of Nucleic Acid Amplification Testing Screening to Identify Acute and Early HIV Infection
The investigators propose to study the impact of nucleic acid amplification testing (NAT) screening for acute Human Immunodeficiency Virus (HIV) and Hepatitis C (HCV) infections and Less-Sensitive Enzyme linked Immunoassay…
- Trial name
- NCT01434706
- Testing
- Nucleic Acid Amplification Testing
- Where
- 5 sites in United States
- Volunteers
- 22,607 people
- Sponsor
- University of California, San Diego
HIV Infections
A Mindfulness Based Approach to HIV Treatment Side Effects
We are exploring the effect that an 8 week stress reduction program based in mindfulness practices will have on the experience of medication side effects reported by HIV-infected men and women taking antiretroviral therapy.
- Trial name
- NCT00312936
- Testing
- Mindfulness-based Stress Reduction (MBSR)
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of California, San Francisco
HIV Infection
Study of Safety and Pharmacokinetics in Healthy Volunteers and Safety, Tolerability and Antiviral Activity of VM-1500 in Patients With Human Immunodeficiency Virus-1 Infection
A combined Phase Ib and IIa randomized, placebo-controlled, double-blind study of VM-1500 in healthy subjects and in patients with HIV-1 infection that are antiretroviral therapy naïve.
- Trial name
- NCT02485509
- Where
- Thailand
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Viriom
HIV Infections
Novel Internet-Based Interventions to Reduce Sexual Risk Among Men Who Have Sex With Men
The purpose of this study is to develop and test the efficacy of online HIV risk reduction interventions among men who have sex with men.
- Trial name
- 5Part (NCT00649701)
- Testing
- Standard Text-Based Prevention Web Page, The Morning After, Talking About HIV
- Where
- United States
- Volunteers
- 3,097 people, healthy volunteers welcome
- Sponsor
- Public Health Solutions
HIV Infections
A Pilot Pharmacokinetic Phase I Evaluation of BI-RG-587 in HIV-Infected Children
To generate initial information on the pharmacokinetics (blood levels) and dose proportionality of nevirapine (BI-RG-587) plasma levels in HIV-infected children; to assess the safety and tolerance of single rising oral doses of…
- Trial name
- NCT00000634
- Testing
- Nevirapine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV
Pre-Exposure Prophylaxis (PrEP) Provision for Ugandan Fisherfolk
This study is a pilot test of enhancements to the standard of care for providing PrEP in Ugandan fishing communities. The specific aims are to conduct a mixed-methods study assessing enhancements to the standard of care for…
- Trial name
- NCT05084716
- Testing
- Enhanced PrEP provision
- Where
- 2 sites in Uganda
- Volunteers
- 885 people, healthy volunteers welcome
- Sponsor
- RAND
Hepatitis C
Grazoprevir (MK-5172) and Elbasvir (MK-8742) Combination for Chronic Hepatitis C Virus (HCV) Genotypes 1, 4, and 6 (MK-5172-065)
This is a randomized, multi-site, placebo-controlled trial of a fixed dose combination (FDC) of grazoprevir (MK-5172) 100 mg + elbasvir (MK-8742) 50 mg in participants with chronic Hepatitis C Virus (HCV) genotype (GT) 1, GT4 or…
- Trial name
- NCT02252016
- Testing
- Grazoprevir + Elbasvir
- Volunteers
- 159 people
- Sponsor
- Merck Sharp & Dohme LLC
Chlamydia
Multi-level Interventions for STD Prevention Among Adolescents
Sexually active adolescents between the ages of 10 and 19 are at extremely high risk for sexually transmitted diseases (STD), including HIV, and teen pregnancy.The overall goal of this research program is to develop, implement…
- Trial name
- NCT00146406
- Testing
- Project Connect
- Where
- United States
- Volunteers
- 36,502 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV Infections
Study of Nevirapine and Prednisone to Determine the Safety and Effectiveness in Preventing Nevirapine Associated Rash in Human Immunodeficiency Virus (HIV) Infected Patients
Study to determine the incidence of rash between the group receiving nevirapine without prednisone and the group receiving nevirapine with prednisone
- Trial name
- NCT02184299
- Testing
- Nevirapine, Prednisone
- Volunteers
- 138 people
- Sponsor
- Boehringer Ingelheim
HIV Infections
A Study to Evaluate Various Combinations of Anti-HIV Medications to Treat Early HIV Infection
The purpose of this study is to compare the effectiveness of various combinations of anti-HIV drugs in HIV-positive men and women.
- Trial name
- NCT00000919
- Testing
- Indinavir sulfate, Lamivudine/Zidovudine, Ritonavir
- Where
- 80 sites in United States, Italy and 1 more
- Volunteers
- 900 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Effects on the Immune System of Anti-HIV Drugs in Patients Recently Infected With HIV
The purpose of this study is to find out whether these powerful combinations of anti-HIV drugs are safe and effective for use in patients in the early stages of HIV infection and to find out how patients' immune systems react to…
- Trial name
- NCT00001119
- Testing
- Tetanus Toxoid Vaccine, Indinavir sulfate, Lamivudine/Zidovudine
- Where
- 12 sites in United States, Australia
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
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