Clinical trials: HPV Testing
Cervical Cancer Screening
Single Visit Clinical Validation of ScreenFire, a Low-Cost HPV Test: Efficacy and Cost Effectiveness (Phase 2)
In high-income countries, prevention strategies have led to declines in cervical cancer rates by more than 75% in high-income countries.
- Trial name
- SCALE AIM 2 (NCT07538050)
- Testing
- Same day screen and treat
- Where
- El Salvador
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Human Papillomavirus Infection
APTIMA HPV 16 18/45 Genotype Assay on the TIGRIS DTS System in Women With ASC-US or Negative Pap Test Results
In both the ASC-US Study and Adjunct Study populations, the objectives are to: evaluate the performance characteristics of the AHPV-GT Assay for detecting cervical disease in women with APTIMA HPV Assay positive results and…
- Trial name
- AHPV-GT (NCT01384370)
- Where
- 3 sites in United States
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Gen-Probe, Incorporated
Cervical Cancer
HPV DNA Testing Through Mobile Mammography Unit
Invasive cervical cancer incidence and mortality can be dramatically reduced through early detection and treatment, but many women do not complete screening at recommended intervals.
- Trial name
- NCT03551028
- Testing
- HPV self collection
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Uterine Cervical Neoplasms
Evaluating the Impact of Different Methods of HPV DNA Testing for Cervical Cancer Screening in Primary Care Settings
Primary objective of the study is to determine the extent that offering of self-sampling in addition to clinician-sampling Human Papillomavirus (HPV) DNA testing will increase detection of HPV DNA through an increase in uptake…
- Trial name
- NCT06528184
- Testing
- Self-sampled HPV DNA testing, Clinician-sampled HPV DNA test
- Where
- Singapore
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- National Healthcare Group Polyclinics
HPV Infection
Evaluation of the Prevalence of Oral HPV Infection in Patients Who Are Positive to the PAP-test
The present cross-sectional study aims to assess the prevalence and type distribution of oral HPV infection in PAP-test-positive women aged ≥18 years.
- Trial name
- NCT05949398
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Catania
Vaccination Hesitancy, Human Papillomavirus Vaccination
Testing the Persuasiveness of Pro-inoculation Arguments
The investigators will recruit a national sample of parents of 7-10-year-olds to complete an argument strength ranking for either a simple forwarding message or between 3 and 6 randomly selected arguments from an overall set of…
- Conditions
- Vaccination Hesitancy, Human Papillomavirus Vaccination, Vaccine Refusal
- Trial name
- NCT05804825
- Testing
- Argument inoculation messages, Simple forewarning message
- Where
- United States
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hpv
Effectiveness of HPV Vaccine Among Adolescents and Reproductive Women
To assess the effectiveness of HPV vaccine 2 doses or less to prevent HPV high risk infection among adolescents and adults. We conduct the test-negative control study including 12-45 women who interest to do a check-up pap smear.
- Trial name
- NCT06220747
- Where
- 2 sites in Thailand
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Human Papilloma Virus-Related Carcinoma
Human Papillomavirus Screening and Vaccine Readiness Program
Public Health Research Institute (PHRI) is carrying out a 15 month research and advocacy project with the goals of generating critical data on acceptability, identifying determinants and facilitators of HPV vaccine uptake in…
- Trial name
- NCT00863096
- Testing
- Gardasil
- Where
- India
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Public Health Research Institute, India
Cervical Cancer
Screen and Treat for Cervical Cancer Prevention
The study measures the impact of "screen-and-treat" on the prevalence of high-grade cervical intraepithelial neoplasia and cancer (CIN 2+).
- Trial name
- SAT (NCT00233727)
- Testing
- HPV DNA Testing + Cryosurgery, VIA + Cryosurgery
- Where
- South Africa
- Volunteers
- 7,123 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cervical Cancer
SUCCESS - Feasibility of HPV Testing and Treatment of Pre-cancerous Cervical Cancer Lesions (HPV Study)
The goal is to assess the feasibility and acceptability of integrating into existing health systems, provision of HPV screening and treatment of pre-cancerous cervical cancer lesions with ablative treatments in Burkina Faso, Côte…
- Trial name
- HPV (NCT05133661)
- Testing
- HPV testing
- Where
- 4 sites in Burkina Faso, Côte d’Ivoire and 2 more
- Volunteers
- 17,602 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Cervical Intraepithelial Neoplasia, Cervical Cancer
HPV Integration Testing for Human Papillomavirus-Positive Women
Papanicolaou (Pap) triage, with high specificity, has been recommended for primary Human papillomavirus (HPV) testing but is flawed by poor sensitivity and cytologist dependence.
- Trial name
- NCT02576262
- Testing
- TCT，HPV，colposcopic inspection
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Cervical Cancer, Human Papillomavirus Infection
Effect of Health Belief Model-Based Education on Cervical Cancer Knowledge and HPV Vaccine Attitudes in Women
This study evaluated the effect of a Health Belief Model-based educational intervention on women's knowledge of cervical cancer and their attitudes and beliefs toward HPV vaccination.
- Conditions
- Cervical Cancer, Human Papillomavirus Infection, Preventive Health Services
- Trial name
- HBM-HPV (NCT07521163)
- Testing
- Health Belief Model-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Muhammet Faruk Yigit
HPV, HPV Associated Cancers
Emergency Department-based Cervical Cancer Screening Through Self-sampling
This project will compare the uptake of cervical cancer screening through ED HPV sampling among patients presenting to the ED.
- Conditions
- HPV, HPV Associated Cancers, HPV Cancers, Cervical Cancer Screening
- Trial name
- NCT07345897
- Testing
- Cervical Cancer Screening
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Cervical Cancer, High Grade Sil
Screening Study for Cervical Pre-cancer and Cancer Prevention in South African Women.
Nearly 8 000 new cervical cancer cases are diagnosed in South Africa per year; many are still undiagnosed and about 50% of diagnosed cases succumb per year.
- Conditions
- Cervical Cancer, High Grade Sil, CIN2
- Trial name
- DiaVACCS (NCT02956031)
- Testing
- Screening, Colposcopy, LLETZ
- Where
- South Africa
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Pretoria
Behavior, Information Seeking, Intention
Testing Messages to Promote HPV Vaccination
Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide. Hispanic women have the highest rates of HPV-related cervical cancer compared to all other groups in the U.S.
- Conditions
- Behavior, Information Seeking, Intention, Vaccine Hesitancy
- Trial name
- NCT05206669
- Testing
- Health Messages
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
N/A - Healthy Subjects
Engaging College Students in Developing and Testing a Video-based Intervention for HPV Vaccination Promotion
HPV vaccines offer hope against HPV-associated cancers for males and females; however, the rate of vaccination has not reached projected public health goals.
- Trial name
- HPV videos (NCT06397378)
- Testing
- short videos related to HPV and the HPV vaccine, CDC HPV Fact Sheet
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Papilloma Viral Infection, Vaccine Hesitancy
Communication Strategies to Increase HPV Vaccinations
This research aims to identify communication strategies to improve the uptake of vaccines using an experimental design, focusing on the Human Papillomavirus (HPV) vaccine, which is highly effective in preventing HPV-related…
- Conditions
- Papilloma Viral Infection, Vaccine Hesitancy, Communication
- Trial name
- NCT06784960
- Testing
- HPV Message 1, HPV Message 2, HPV Message 3
- Where
- United States
- Volunteers
- 9,002 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Human Papilloma Virus Infection
Understanding Women's Values in Managing Human Papillomavirus (HPV)
Almost all cervical cancers are caused by infection with a high-risk (hr) HPV. In March 2020, the Scottish Cervical Screening programme changed from a test to look for abnormal cervical cells caused by hr-HPV to a test that looks…
- Trial name
- NCT06123533
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
HPV Infection, HPV Positive Oropharyngeal Squamous Cell Carcinoma
The SPOT-HPV Study
The purpose of this research is to evaluate a new test for oral HPV DNA in saliva ('oral rinse test').
- Trial name
- NCT05524025
- Testing
- Salivary TTMV-HPV DNA Test, Blood TTMV-HPV DNA Test
- Where
- 2 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Cervical Cancer
Self-Sampling for Human Papillomavirus (HPV) Testing in African American Women - Mississippi Delta
The purpose of this study is to examine the efficacy and costs of this patient-centered approach ("Choice" between two cervical cancer screening modalities) in adherence to cervical cancer screening as compared to the current…
- Trial name
- HPV (NCT03713710)
- Testing
- Pap testing, Choice
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham