Clinical trials: Halitosis, open to volunteers
Plaque-Induced Gingivitis, Dental Plaque Accumulation
Innovative Mouthwash in School-Aged Children With Fixed Orthodontic Appliances
Fixed metal orthodontic appliances create additional plaque-retentive areas around brackets, archwires and ligatures, making mechanical plaque control more difficult in children and adolescents.
- Conditions
- Plaque-Induced Gingivitis, Dental Plaque Accumulation, Halitosis
- Trial name
- NCT07710144
- Testing
- Test mouthwash, Chlorhexidine-containing mouthwash
- Where
- Bulgaria
- Volunteers
- 90 people
- Sponsor
- Plovdiv Medical University
Gingivitis, Halitosis
Evaluation of the Safety and Efficacy of SALI-10 Probiotic Lozenges
Gingivitis is among the most common oral conditions, affecting 50-90% of adults globally. It is a reversible inflammatory disease triggered primarily by the accumulation of microbial plaque on teeth and gingival tissues.
- Trial name
- NCT07508839
- Testing
- 3B SALI-10 Lozenge
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ostia Sciences
Periodontitis, Halitosis
The Additional Effect of Tongue Scraping on Halitosis Parameters in Initial Periodontal Therapy
Periodontitis can lead to tooth loss which may impair chewing ability and aesthetics. In addition, periodontitis can give rise to halitosis.
- Conditions
- Periodontitis, Halitosis, Tongue Condition
- Trial name
- NCT06091228
- Testing
- tongue scraper
- Where
- Belgium
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Oral Malodor (Halitosis), Oral Dryness
Effects of a 50+ Toothpaste on Halitosis and Oral Comfort in Healthy Adults
The goal of this clinical trial is to compare a toothpaste designed for adults aged 50 years and older with a standard toothpaste in orally healthy adults.
- Trial name
- HALI-50PLUS (NCT07780474)
- Testing
- 50+ Toothpaste, Standard Fluoride Toothpaste
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Halitosis
Oral Probiotics for Halitosis in Healthy Adults
The aim of this study is to evaluate efficacy of a probiotic lozenge containing BLIS M18, BLIS K12 and a prebiotic in healthy adults.
- Trial name
- NCT07384130
- Testing
- In this study, a probiotic lozenge formulation containing S. salivarius K12, M18 and prebiotic will be evaluated for its potential to improve bad breath
- Where
- New Zealand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- John Hale
Halitosis, Dentistry
Effect of Dental Education Duration on Halitosis and Associated Factors
The study population will consist of undergraduate dental students enrolled at Recep Tayyip Erdoğan University Faculty of Dentistry.
- Trial name
- NCT07740876
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Halitosis, Periodontal Diseases
Tedlar Bag Stability of Volatile Sulfur Compounds for Remote Halitosis Diagnosis
Halitosis, or bad breath, affects about 30% of people worldwide and is most often caused by oral diseases such as periodontitis.
- Trial name
- Malodorix (NCT07602309)
- Testing
- Breath sample collection with Tedlar bags PLV 0.6L and plastic syringe 1cc
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Halitosis
Investigating the Effect of Chlorine Dioxide and Chlorhexidine Mouthwash on Bad Breath
The ODOR trial will be a single-centric, double-blinded, parallel-group, double-armed pilot randomized controlled trial with a non-inferiority design.
- Trial name
- NCT06219226
- Testing
- Chlorine dioxide mouthwash, Chlorhexidine mouthwash
- Where
- Hungary
- Volunteers
- 60 people
- Sponsor
- Semmelweis University
Periodontal Diseases, Oral Halitosis
The Effect of Regular Home Use of Dual-light Antibacterial Photodynamic Therapy (aPDT) or the Use of a Powered Toothbrush in Older Individuals With Periodontitis and Mild Cognitive Impairment.
Objective: To compare three different oral hygiene regimens regarding plaque index (PI), bleeding on probing (BOP), the number of deepened periodontal pockets ≥4 mm (PPD), oral halitosis, and changes in oral health-related…
- Trial name
- e-DENT II (NCT07166224)
- Testing
- Oral-B Powered toothbrush, Dual-Light aPDT Treatment - Lumoral
- Where
- 2 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Blekinge Institute of Technology
Halitosis, Mouth Disease
Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.
The aim of the study: To assess the efficacy of antioxidant (resveratrol) mouthwash in reducing the level of p. gingivitis and oral malodor over 7 day period among undergraduate dental student patients from Mustansiriyah…
- Conditions
- Halitosis, Mouth Disease, Plaque Induced Gingival Disease, Bleeding Gum
- Trial name
- NCT06882564
- Testing
- resveratrol mouthwash, Chlorhexidine mouthwash (0.2%)
- Where
- Iraq
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Plaque Induced Gingivitis, Halitosis
Role of Kefir Mouth Wash in Oral Health Status Amelioration
The present research aims to evaluate the efficiency of kefir mouthwash in enhancing oral health status by employing an in vivo experimental approach.
- Conditions
- Plaque Induced Gingivitis, Halitosis, Oral Disease
- Trial name
- NCT06900881
- Testing
- Kefir Mouth Wash, Chlorhexidine 0,12%Biofresh Mouthwash
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Halitosis, Orthodontic Appliance Complication
Chios Mastic Toothpaste and Halitosis and Oral Hygiene in Orthodontic Patients
The aim of this trial was to investigate the effect of mastic toothpaste on halitosis using as proxy the levels of the Volatile Sulfur Compounds (VSCs), and the effect on plaque and gingival indices in adolescents undergoing…
- Trial name
- NCT06766097
- Testing
- mastic toothpaste
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Athens
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Obesity, Bariatric Surgery Candidate
Halitosis, Sleep and Mental Health in Bariatric Surgery Candidates
This study aims to evaluate psychological distress, sleep quality, and halitosis in obese patients during the preoperative period of bariatric surgery.
- Conditions
- Obesity, Bariatric Surgery Candidate, Halitosis, Sleep Disorder
- Trial name
- NCT07175142
- Volunteers
- 110 people
- Sponsor
- University of Nove de Julho
Halitosis
Comparative Study Between Photodynamic Therapy with LED Associated with Probiotics in the Treatment of Halitosis
Halitosis is a term that defines any odor or bad smell coming from the oral cavity, which can have a local or systemic origin. This project aims to verify if there is a difference in the effectiveness of treatment with…
- Trial name
- NCT06583720
- Testing
- Oral hygiene at home, aPDT, Probiotics
- Where
- Brazil
- Volunteers
- 92 people
- Sponsor
- University of Nove de Julho
Healthy, Halitosis
Effectiveness of Aquamin® in Mitigating Halitosis
The purpose of this study is to assess whether Aquamin®, a multi-mineral natural product from red marine algae, can help reduce halitosis when taken for 90 days.
- Trial name
- NCT05058638
- Testing
- Aquamin
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Halitoses
Probiotic Vs Zinc Chlorhexidine Zn/CHX Mouthwashes in Control Halitosis and Plaque in Fixed Orthodontic Patients
This study aims to determine the effect of probiotics and Zn/CHx mouthwashes on plaque accumulation and halitosis in fixed orthodontic patients.
- Trial name
- NCT07693972
- Testing
- Probiotic (L. brevis CD2 lozenges), Zinc chlorhexidine mouth wash
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sara M Almshhadany
Type 2 Diabetes, Halitosis
Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus
The goal of this clinical trial is to evaluate the effectiveness of periodontal treatment associated with the use of a tongue scraper, compared with the same treatment combined with antimicrobial photodynamic therapy (aPDT), in…
- Conditions
- Type 2 Diabetes, Halitosis, Periodontitis
- Trial name
- NCT07463859
- Testing
- Scaling and root planing, Photodynamic Therapy with Conventional Methylene Blue
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo