Clinical trials: Hallucinations, Auditory
Schizophrenia
A Study on the Brain Mechanism of cTBS in Improving Medication-resistant Auditory Hallucinations in Schizophrenia
This study is dedicated to exploring the brain mechanism of medication-resistant auditory hallucinations and developing effective treatment methods for them by using both cross-sectional and longitudinal designs.
- Trial name
- NCT05039489
- Testing
- Antipsychotic drugs, cTBS（the left temporoparietal cortex as the stimulation target）, cTBS （the left cerebellum Crus II as the stimulation target）
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University
Auditory Hallucination, Verbal, Treatment-resistant Schizophrenia
Avatar Therapy in Comparison to Cognitive Behavioral Therapy for Treatment-resistant Schizophrenia
Schizophrenia is associated with long-lasting health, social and financial burden for patients, families, caregivers and society. Unfortunately, 25-30% of schizophrenia patients respond poorly to antipsychotic medication.
- Trial name
- NCT03585127
- Testing
- Cognitive Behavioral Therapy, Avatar Therapy
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Audio Visual Hallucinations, Neurofeedback
Rt-fMRI Neurofeedback and AH in Schizophrenia
Auditory hallucinations in schizophrenia are one of the major symptoms of this disease and a major source of psychological discomfort. They are often difficult or impossible to treat with existing methods.
- Conditions
- Audio Visual Hallucinations, Neurofeedback, Schizophrenia, Superior Temporal Gyrus
- Trial name
- NCT03504579
- Testing
- rt-fMRI neurofeedback
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Schizophrenia; Psychosis
Efficacy of Maintenance Repetitive Transcranial Magnetic Stimulation (rTMS) in Auditory Verbal Hallucinations
Repetitive transcranial magnetic stimulation (rTMS) can alleviate persistent auditory verbal hallucinations (AVH) in schizophrenic patients, but the classical procedure with low-frequency stimulation for several weeks upon the…
- Trial name
- MAINSTIM (NCT05550155)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
Auditory Hallucination, Verbal
Effects of Transcranial Direct Current Stimulation (tDCS) on Persistent Auditory Verbal Hallucinations in Schizophrenia
Many individuals with schizophrenia struggle with auditory verbal hallucinations (AVHs). In some cases, these AVHs can be resistant to medication treatment.
- Trial name
- NCT04222582
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Schizophrenia and Related Disorders
Individualized Repetitive Transcranial Magnetic Stimulation for Auditory Verbal Hallucinations
The Repetitive Transcranial Magnetic Stimulation (rTMS) is a type of brain stimulation that uses a magnet to change activity in the brain.
- Trial name
- NCT05319080
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Columbia University
Schizophrenia, Hallucinations
Efficacy of tDCS in the Treatment of Resistant Auditory Hallucinations in Schizophrenia
The regions which are assumed to underlie the pathophysiology of schizophrenia, namely hypoactivity at the prefrontal level and pathological hyperactivity of the associative regions of the language located in the left…
- Conditions
- Schizophrenia, Hallucinations, Refractory Schizophrenia
- Trial name
- TDCSHALLU (NCT04352569)
- Testing
- transcranial direct current stimulation
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre hospitalier de Ville-Evrard, France
Nurses, Schizophenia Disorder
The Effectiveness of Combining AR/VR Technology in Virtual Clinical Auditory Hallucinations on the Comprehensive Auditory Hallucination Nursing Competency of Psychiatric Nurses
This study aims to develop and evaluate a Virtual Reality (VR) Auditory Hallucination Program to enhance psychiatric nurses' comprehensive care competence in managing auditory hallucinations among patients with schizophrenia.
- Conditions
- Nurses, Schizophenia Disorder, Hallucinations, Auditory
- Trial name
- NCT06938997
- Testing
- Virtual clinical auditory hallucination solution combining AR/VR technology, Auditory Hallucination Care Video
- Where
- 4 sites in Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Schizophrenia, Schizoaffective Disorder
Transcranial Current Stimulation as a Treatment for Auditory Hallucinations in Schizophrenia
Investigating the effect of non-invasive transcranial current stimulation on auditory hallucinations in patients with schizophrenia.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Auditory Hallucinations
- Trial name
- NCT01963676
- Testing
- tDCS
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of North Carolina, Chapel Hill
Schizophrenia, Hallucinations
Evaluation of Internet-based Cognitive Behavioral Self-help Treatments for People With Psychosis
Schizophrenia is a severe mental disorder which is accompanied by an enormous individual and societal burden. Despite established efficacy of cognitive behavioral therapy for psychosis (CBTp), its dissemination into routine…
- Conditions
- Schizophrenia, Hallucinations, Persecutory Delusion
- Trial name
- EviBaS (NCT02974400)
- Testing
- Internet-based, CBT-oriented, guided self-help
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 101 people
- Sponsor
- University of Bern
Schizophrenia
Effect of Repetitive Transcranial Magnetic Stimulation on Resting State Brain Activity in Schizophrenia
This study compares the efficacy of low and high frequency repetitive transcranial magnetic stimulation (rTMS) as a means of treating subjects with schizophrenia. Magnetic pulses delivered over the scalp cause brain activity.
- Trial name
- NCT01620086
- Testing
- Active Repetitive Transcranial Magnetic Stimulation 1 Hz, Active Repetitive Transcranial Magnetic Stimulation 10 Hz, Active control site Repetitive Transcranial Magnetic Stimulation at 1Hz
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Schizophrenia
EEG-based Neurofeedback for Auditory Verbal Hallucinations (HALFEED)
This study's primary objective is to perform a randomized controlled pilot study to assess the feasibility of using EEG-based neurofeedback to reduce the severity of treatment-resistant auditory verbal hallucinations ('hearing…
- Trial name
- HALFEED (NCT03852706)
- Testing
- LORETA, Treatment as usual
- Where
- Ireland
- Volunteers
- 4 people
- Sponsor
- University of Dublin, Trinity College
Schizophrenia, Hallucinations
Changes in Auditory Verbal Hallucination During Atypical Antipsychotic Treatment of Patients With Schizophrenia
The purpose of this study is to evaluate the changes in various aspects of auditory verbal hallucinations during 24-week antipsychotic treatment in naturalistic condition.
- Trial name
- NCT00328952
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Schizophrenia, Schizoaffective Disorder
Effect of Neuroplasticity Modulation in tDCS Treatment Response Among Schizophrenia Patients With Auditory Hallucination
Schizophrenia is a severe neuropsychiatric disorder of the brain and is also one of the top ten disabling diseases. A common symptom of schizophrenia (SCZ) is hearing voices inside one's heads which others do not.
- Trial name
- NCT04629352
- Testing
- Verum Accelerated Transcranial Direct Current Stimulation (acctDCS)
- Where
- India
- Volunteers
- 72 people
- Sponsor
- National Institute of Mental Health and Neuro Sciences, India
Auditory Hallucinations
Efficacy and Safety of Bilateral Theta Burst Stimulation for the Treatment of Auditory Hallucinations
First clinical studies indicate an effect of repetitive transcranial magnetic stimulation(rTMS) in the treatment of auditory hallucinations (AH). However, effect size, optimal stimulation site and parameters are unclear.
- Trial name
- TBS-H (NCT01478880)
- Testing
- continuous theta burst stimulation (cTBS)
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- University Hospital Tuebingen
Schizophrenia, Visual Hallucination
Visual Information Processing in Schizophrenia Patients With Visual Hallucinations
Occurrence of visual hallucinations (VHs) in schizophrenia depend in part on disorders in the processing of late visual information (Top-Down).
- Conditions
- Schizophrenia, Visual Hallucination, Auditory Hallucination, False Perception
- Trial name
- SHALL (NCT03188133)
- Testing
- behavioral task : emotional priming
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Auditory Hallucination, Psychotic Disorders
Avatar-mediated Therapy Versus Cognitive Behavioural Therapy for Persisting Experiences of Hearing Voices
The aim of this study is to compare the effects of a new psychological therapy, Avatar Therapy, to the current standard therapy, Cognitive Behavioural Therapy (CBT), in improving outcomes in people living with psychotic disorders…
- Conditions
- Auditory Hallucination, Psychotic Disorders, Schizophrenia and Related Disorders
- Trial name
- AMETHYST (NCT05982158)
- Testing
- Avatar therapy, Cognitive behavioural therapy (CBT)
- Where
- Australia
- Volunteers
- 212 people
- Sponsor
- Swinburne University of Technology
Schizophrenia, Hallucinations, Auditory
fMRI-based Neurofeedback to Relieve Drug-resistant Auditory Hallucinations
The INTRUDE trial aims at assessing the efficacy of an fMRI-based neurofeedback procedure on drug-resistant auditory hallucinations.
- Conditions
- Schizophrenia, Hallucinations, Auditory, Hallucinations, Visual
- Trial name
- INTRUDE (NCT04798131)
- Testing
- Active neurofeedback procedure
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Lille
Hallucinations, Auditory
The ECHO Study: Compassion-focused Therapy for Young Voice Hearers and Their Caregivers
In this project, a 10-session treatment program was developed aimed at young people who experience voice hearing. The treatment has potential to easily be implemented in everyday clinical practice in Child and Adolescent…
- Trial name
- ECHO (NCT07314515)
- Testing
- ECHO Manualized CFT treatment for young voice heares
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Schizophrenia, Schizo Affective Disorder
Targeting Auditory Hallucinations With Alternating Current Stimulation
Investigating the effects of non-invasive transcranial alternating current stimulation (tACS) as a treatment for auditory hallucinations in patients with schizophrenia.
- Trial name
- STILL3 (NCT03221270)
- Testing
- tACS treatment week, Maintenance tACS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill