Clinical trials: Hand Eczema
Chronic Hand Eczema
A 24 Week Trial to Compare the Efficacy and Safety of Delgocitinib Cream 20 mg/g Twice-daily With Alitretinoin Capsules Once-daily in Adult Participants With Severe Chronic Hand Eczema
This is a 24-week study in adult participants with severe chronic hand eczema (CHE) and with a documented inadequate response to treatment with topical corticosteroids (TCS) or for whom TCS are documented to be otherwise…
- Trial name
- DELTA FORCE (NCT05259722)
- Testing
- Delgocitinib, Toctino
- Where
- 102 sites in Austria, Canada and 8 more
- Volunteers
- 513 people
- Sponsor
- LEO Pharma
Hand Eczema
Dupilumab in Severe Chronic Hand Eczema
The purpose of this study is to investigate the efficacy of dupilumab in hand eczema patients with an inadequate response or intolerance to alitretinoin.
- Trial name
- DUPSHE (NCT04512339)
- Testing
- Dupilumab
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Chronic Hand Eczema
Efficacy and Safety of Dupilumab Chronic Hands Eczema Refractory to Highly Potent Topical Corticosteroids
Dupilumab has recently demonstrated high efficacy and good safety profile in the treatment of moderate-to-severe atopic dermatitis.
- Trial name
- DUPECZEMAIN (NCT03861455)
- Testing
- Dupilumab
- Where
- 4 sites in France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Toulouse
Hand Eczema
Multicenter Clinical Study to Examine the Efficacy and Safety of Zarzenda in Patients With Hand Eczema
To show efficacy of Zarzenda in the treatment of hand eczema
- Trial name
- NCT00488241
- Testing
- Zarzenda
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Bayer
Chronic Hand Dermatitis
Comparison Study With E-DO in Chronic Hand Dermatitis
The objective of this study is to evaluate the topical E-DO in patients with Chronic Hand Dermatitis (fu kuei shou).
- Trial name
- NCT00556855
- Testing
- E-DO
- Where
- Taiwan
- Volunteers
- 67 people
- Sponsor
- HenKan Pharmaceutical Co., Ltd.
Atopic Dermatitis, Contact Dermatitis
Methotrexat to Hand Eczema in the BIOSKIN Cohort
Handeczema is a common chronic skin disease that markedly affect health and quality of life. Effective treatment is limited by the lack of biomarkers that can predict disease course, comorbidities and treatment response.
- Conditions
- Atopic Dermatitis, Contact Dermatitis, Hand Eczema
- Trial name
- BIOSKIN: MTX (NCT07338305)
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lone Skov
Chronic Hand Eczema
PPDTM CorEvitasTM Chronic Hand Eczema (CHE) Drug Safety and Effectiveness Registry
The design is a prospective, observational registry for subjects with CHE under the care of dermatology or other qualified healthcare provider.
- Trial name
- NCT07598058
- Testing
- Observational (Non-Interventional) Registry
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- CorEvitas
Dermatitis Hand, Skin Abnormalities
Hand Sanitizer Effects on the Skin Barrier
Hand washing and the use of hand sanitizers are important interventions in disease prevention. Engaging in frequent hand washing is especially effective in preventing the spread of viruses, as this removes microbes and prevents…
- Conditions
- Dermatitis Hand, Skin Abnormalities, Atopic Dermatitis, Atopic Dermatitis Eczema
- Trial name
- NCT04525521
- Testing
- Hand sanitizer and hand washing
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Jewish Health
Psoriasis, Contact Dermatitis of Hand
An Open-label Controlled Trial: Effectiveness of Balneotherapy in Palmoplantar Psoriasis and Contact Dermatitis.
Patients who had an indication for phototherapy were included in this study. The treatment was used as a monotherapy protocol. The standard protocol for bathing PUVA involved applying 0.01% bath psoralen for 15 minutes, while the…
- Trial name
- NCT06458868
- Testing
- salt water or tap water before UVA
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ankara University
Chronic Hand Eczema
Efficacy, Safety, and Tolerability of Abrocitinib in Subjects With Moderate to Severe Chronic Hand Eczema Refractory to Corticosteroid Therapy
This study aims to evaluate the safety, efficacy and tolerability of abrocitinib in subjects with moderate to severe chronic hand eczema, and its effects on skin biomarkers using a noninvasive method of tape stripping.
- Trial name
- NCT06283550
- Testing
- Abrocitinib 200 mg, Abrocitinib 100 mg
- Where
- 12 sites in Canada, Poland
- Volunteers
- 82 people
- Sponsor
- Innovaderm Research Inc.
Chronic Hand Eczema
Proof of Concept, Twice Daily Applications of LEO 124249 Ointment in the Treatment of Chronic Hand Eczema
To compare the efficacy of twice daily applications of LEO 124249 ointment with LEO 124249 ointment vehicle for up to 8 weeks in the treatment of subjects with chronic hand eczema.
- Trial name
- NCT02664805
- Testing
- LEO 124249 ointment, LEO 124249 ointment vehicle
- Where
- Germany
- Volunteers
- 91 people
- Sponsor
- LEO Pharma
Chronic Hand Dermatitis
Apremilast and Moderate to Severe Chronic Hand Dermatitis
Investigators have designed a pilot study involving chronic hand dermatitis (CHD) patients who attend the dermatology clinic at the George Washington Medical Faculty Associates (GW MFA) in order to assess the efficacy and safety…
- Trial name
- CHD (NCT03741933)
- Testing
- Apremilast 30mg
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- George Washington University
Chronic Hand Eczema
Efficacy and Safety of Delgocitinib Cream in Adults With Moderate to Severe Chronic Hand Eczema
This was a 16-week study in adult participants with chronic hand eczema (CHE). > The participants visited the clinic regularly to have the study doctor assess their CHE and to answer questions about itch, pain, CHE symptoms, and…
- Trial name
- DELTA 1 (NCT04871711)
- Testing
- Delgocitinib cream, Cream vehicle
- Where
- 54 sites in Canada, France and 4 more
- Volunteers
- 487 people
- Sponsor
- LEO Pharma
Hand Dermatoses
Safety and Efficacy Study of Triamcinolone Acetonide DuraPeel to Treat Hand Dermatitis
The purpose of this study is to determine whether Triamcinolone Acetonide (TAC) DuraPeel is safe and effective in the treatment of hand dermatitis.
- Trial name
- TAC-202 (NCT00890968)
- Testing
- Triamcinolone Acetonide (TAC) DuraPeel
- Where
- 3 sites in United States
- Volunteers
- 56 people
- Sponsor
- ZARS Pharma Inc.
Occupational Contact Dermatitis
Occupational Hand Eczema - Testing of a Prevention-concept
Randomised controlled trial examining the effect of decreased waiting time for the first doctors' appointment, patient education, glove counselling and counselling at departments of social or occupational medicine on severity of…
- Trial name
- NCT04790799
- Testing
- Treatment at the skin department at Gentofte Hospital
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- National Allergy Research Center, Denmark
Hand Dermatoses
Efficacy and Safety of a Retinoid for the Treatment of Severe Chronic Hand Dermatitis
The purpose of the study is to determine the therapeutic effect of alitretinoin, a retinoid, on severe, therapy refractory chronic hand dermatitis.
- Trial name
- NCT00124475
- Testing
- alitretinoin
- Where
- Germany
- Volunteers
- 1,035 people
- Sponsor
- Basilea Pharmaceutica
Eczema
Efficacy and Safety of a Retinoid in the Treatment of Severe Chronic Hand Eczema
The purpose of this study is to investigate the safety and efficacy of alitretinoin in the treatment of severe chronic hand eczema that does not respond to treatment with potent topical steroids.
- Trial name
- HANDEL (NCT00817063)
- Testing
- alitretinoin
- Where
- 70 sites in United States
- Volunteers
- 599 people
- Sponsor
- Stiefel, a GSK Company
Dermatitis, Chronic
Ethanol-Free Clobetasol Propionate Foam 0.05% (Olux-E Foam) vs Vehicle Foam in the Treatment of Chronic Hand Dermatitis.
The purpose of this study is to determine how clobetasol proprionate foam works against a placebo foam in the treatment of hand dermatitis.
- Trial name
- NCT01323673
- Testing
- clobetasol propionate 0.05%
- Where
- 10 sites in United States
- Volunteers
- 125 people
- Sponsor
- Stiefel, a GSK Company
Chronic Hand Eczema
Phase 2b Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over a 16-week Treatment Period in Adult Subjects With Chronic Hand Eczema
The purpose of this research trial was to test different strengths of a new trial medication, delgocitinib cream 1, 3, 8, and 20 mg/g, and to investigate how treatment with delgocitinib cream affects chronic hand eczema.
- Trial name
- NCT03683719
- Testing
- Delgocitinib cream, Delgocitinib cream vehicle
- Where
- 28 sites in United States, Denmark and 1 more
- Volunteers
- 258 people
- Sponsor
- LEO Pharma
Chronic Hand Eczema (CHE)
Real-World Evidence: Effectiveness and Safety of Chronic Hand Eczema Treatment With Delgocitinib Cream
The goal of this non-interventional study is to assess changes in the signs and symptoms of Chronic Hand Eczema (CHE), as well as the safety profile and use of delgocitinib cream in routine clinical practice, over a 52-week…
- Trial name
- REACHED (NCT07603193)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- LEO Pharma