Clinical trials: Hand and Upper Limb Trauma
Rehabilitation After Neurological or Orthopaedic Injuries
Feasibility of Unsupervised Therapy After Neurological or Orthopaedical Injury in the Home Setting With a Hand Rehabilitation Device (ReHandyBot) and an Assistive Smartphone Application (RehabCoach)
The goal of this clinical trial is to evaluate whether using the ReHandyBot hand rehabilitation device together with the RehabCoach smartphone app can support safe, independent, and effective home therapy in patients with stroke…
- Trial name
- NCT07182734
- Testing
- Supervised and minimally-supervised therapy with ReHandyBot and RehabCoach, Unsupervised Therapy with ReHandyBot and RehabCoach
- Volunteers
- 30 people
- Sponsor
- Swiss Federal Institute of Technology
Cerebrovascular Accident, Traumatic Brain Injury
Telerehabilitation for the Hand and Arm After Stroke and Traumatic Brain Injury
The goal of this project is to develop a low-cost, user-friendly, portable telerehabilitation system for physical therapy of the upper limb after stroke or traumatic brain injury.
- Trial name
- NCT00295399
- Testing
- The Jerusalem Telerehabilitation System
- Where
- 2 sites in Israel
- Sponsor
- Ono Academic College
Carpal Tunnel Syndrome (CTS), Wounds and Injuries, Hands
Evaluation of AI-Mouse Use in Patients With Hand and Wrist Conditions
People with hand and wrist conditions, such as carpal tunnel syndrome or hand injuries, often experience pain and discomfort when using a computer mouse.
- Conditions
- Carpal Tunnel Syndrome (CTS), Wounds and Injuries, Hands, Wounds and Injuries, Wrists, Hand Injuries
- Trial name
- NCT07707089
- Testing
- AI-Assisted Computer Input System, Conventional Computer Mouse
- Volunteers
- 15 people
- Sponsor
- Nazarbayev University
Quadriplegia, Spinal Cord Diseases
Upper Extremity Surgery in Spinal Cord Injury
The goal of the investigators work is to establish how nerve transfers can be best used to improve upper extremity function in patients with cervical level spinal cord injury (SCI).
- Conditions
- Quadriplegia, Spinal Cord Diseases, Spinal Cord Injuries
- Trial name
- NCT01899664
- Testing
- Nerve Transfer Surgery
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Washington University School of Medicine
Hand Fracture, Hand Osteoarthritis
Italian Translation of the Michigan Hand Outcomes Questionnaire
Patient-Reported Outcome Measures (PROMs) are important clinical items for evaluating injuries and recovery of the hand. Some of the most used Questionnaires, unfortunately, are not available in Italian.
- Conditions
- Hand Fracture, Hand Osteoarthritis, Hand Injury Wrist, Hand Sprain
- Trial name
- NCT04527588
- Testing
- Questionaire Michigan
- Sponsor
- University of Zurich
Spinal Cord Injuries
Regain of Arm and Hand Movements in Cervical Spinal Stimulation
We will develop a "bottom to top" approach employing animal models and human testing to determine whether or not non-invasive neuro-modulation of the cervical spinal cord concomitant with upper limb rehabilitation driven by…
- Trial name
- tcSCS (NCT07140354)
- Testing
- cervical transcutaneous spinal cord stimulation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Institut Guttmann
Cervical Spinal Cord Injury
Combined Therapeutic Air Mixture and Electrical Stimulation to Improve Breathing and Hand Function in Spinal Cord Injury
The goal of this clinical trial is to determine whether people with paralysis due to a spinal cord injury can benefit from breathing short intermittent bouts of air with low oxygen (O2) combined with slightly higher levels of…
- Trial name
- AIHH+tSCS (NCT06101199)
- Testing
- Acute Intermittent Hypercapnic Hypoxia, Transcutaneous spinal cord stimulation
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
DeQuervains Tenosynovitis, Lateral Epicondylitis
Dexamethasone Versus Ketorolac Injection for the Treatment of Local Inflammatory Hand and Upper Extremity Disorders
The primary objective of this study is to compare local corticosteroid hand and elbow injections to placebo or ketorolac to determine if there is an equal or better reduction of symptoms for common orthopaedic upper extremity…
- Conditions
- DeQuervains Tenosynovitis, Lateral Epicondylitis, Tennis Elbow, Trigger Finger
- Trial name
- NCT02266433
- Testing
- Ketorolac, Dexamethasone
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- NYU Langone Health
Fracture of Humerus, Fracture of Ulna Radius
3D Geplante Osteosynthesen Mit Patientenspezifischen Zielvorrichtungen
Goal of this study is to evaluate the accuracy of 3D computer-planned fracture fixation with patient-specific instruments for clavicle, upper extremity, lower extremity and pelvis fractures compared with the standard procedure of…
- Conditions
- Fracture of Humerus, Fracture of Ulna Radius, Fracture of Clavicle, Fracture of Hand
- Trial name
- NCT02826538
- Testing
- fracture fixation with patient specific guides, standard procedure of fracture fixation
- Where
- 2 sites in Switzerland
- Volunteers
- 7 people
- Sponsor
- Balgrist University Hospital
Hemiparesis, Cerebral Palsy
Children With Hemiparesis Arm and Hand Movement Project (CHAMP Study)
What is the CHAMP Study? The CHAMP Study is a multisite clinical trial funded by the National Institutes of Health that is comparing the efficacy of alternative therapies for young children with unilateral spastic cerebral palsy…
- Conditions
- Hemiparesis, Cerebral Palsy, Brain Injury
- Trial name
- CHAMP (NCT01895660)
- Testing
- Variations in Pediatric Constraint-Induced Movement Therapy (P-CIMT) versus usual and customary rehabilitation
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Virginia Polytechnic Institute and State University
Brain Injury, Stroke
Using Tablets for Upper Extremity Rehabilitation Post Acquired Brain Injury
The purpose of the study is to test the effectiveness of training using novel tablet applications for hand function, compared to traditional hand exercises.
- Trial name
- TBL (NCT02136433)
- Testing
- Tablet - self exercise, GRASP self exercise
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Carpal Tunnel Syndrome
Reliability And Validity Of Urdu Version Of Disabilities Of The Arm, Shoulder And Hand Questionnaire
The goal of study is to convert Disabilities Of The Arm, Shoulder And Hand Questionnaire into Urdu and test its reliability and validity among the Pakistani citizens.
- Trial name
- NCT05411068
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Riphah International University
Wrist Injury
Use of Virtual Reality to Improve Sensorimotor Function in Patients with Traumatic Wrist and Hand Injuries
The goal of this randomized clinical trial is to compare how the incorporation of Virtual Reality could influence in proprioception, kinesiophobia, functionality and catastrophism in people that are undergoing a rehabilitation…
- Trial name
- NCT06832527
- Testing
- Rehabilitation treatment, Virtual Reality games
- Volunteers
- 79 people
- Sponsor
- University of Malaga
Wrist Injury, Hand and Upper Limb Trauma
Virtual Reality-based Rehabilitation for Traumatic Hand and Wrist Injuries
This randomized controlled trial aims to evaluate the effectiveness of immersive virtual reality (VR)-based Action Observation Therapy (AOT) as an adjunct to conventional rehabilitation in patients with traumatic wrist and hand…
- Conditions
- Wrist Injury, Hand and Upper Limb Trauma, Hand and Forearm Trauma, Muskuloskeletal Diseases
- Trial name
- AOT-VR-HAND (NCT07633769)
- Testing
- Immersive Virtual Reality Action Observation Therapy, Conventional Rehabilitation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Malaga
Wrist Disease, Hand Injuries
Perineural Dexamethasone in Supraclavicular Brachial Plexus Block for Anesthesia After Pediatric Hand/Wrist Surgery
Effect of Perineural Dexamethasone on the Duration of Supraclavicular Brachial Plexus Block for Anesthesia After Pediatric Hand/Wrist Surgery
- Conditions
- Wrist Disease, Hand Injuries, Wrist Injuries, Hand Disease
- Trial name
- NCT06086392
- Testing
- 0.1mg/kg Dexamethasone, 0.05mg/kg Dexamethasone
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Sprain, Strain
Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury
Imprimis Pharmaceuticals is investigating a proprietary, topical cream formulation consisting of 10% ketoprofen (containing 100 mg of ketoprofen in 1gram of cream) for the local treatment of acute musculoskeletal pain.
- Conditions
- Sprain, Strain, Acute Soft Tissue Injury
- Trial name
- NCT00765700
- Testing
- Topical Ketoprofen 10% Cream
- Where
- United States
- Volunteers
- 364 people
- Sponsor
- Imprimis Pharmaceuticals, Inc.
Stroke, Brain Injuries
Safety and Efficacy Evaluation of the Robotic Enhanced Error Training of Upper Limb Function in Post-stroke and Post TBI Participants
Background: Cerebrovascular accident [CVA or commonly known as stroke] and traumatic brain injury (TBI) are common causes of morbidity, and motor impairments.
- Conditions
- Stroke, Brain Injuries, Paresis, Cerebrovascular Disorders
- Trial name
- NCT06010823
- Testing
- PlaXtreme
- Where
- 2 sites in Israel
- Volunteers
- 96 people
- Sponsor
- Reuth Rehabilitation Hospital
Amputation, Traumatic, Wounds and Injury
Human Upper Extremity Allotransplantation: F/U Protocol
Upper extremity allotransplantation is a new procedure which is becoming more common in the United States. Ongoing data collection for research purposes is vital to the long-term assessment as to the safety of the procedure and…
- Conditions
- Amputation, Traumatic, Wounds and Injury, Hand Injuries
- Trial name
- NCT03400345
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Hand Injuries
Comparison of Upper Extremity and Lower Extremity Function and Quick DASH
Patient reported outcome measure (PROM) are a method by which to assess outcomes from a patient perspective. The QuickDASH is a commonly used PROM.
- Trial name
- NCT04291170
- Testing
- QDASH, KOOSJR
- Sponsor
- Stanford University
Cat Bite, Hand Injuries
CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)
Cat bites are puncture wounds that have the potential to seed bacteria deep within the joint capsule, periosteum, and bone. The hand is the most common site of bite injuries.
- Conditions
- Cat Bite, Hand Injuries, Arm Injury, Infection, Bacterial
- Trial name
- CATBITE (NCT05846399)
- Testing
- Amoxicillin/clavulanate, Ciprofloxacin, Clindamycin
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia