Clinical trials: Hashimoto
IgA Nephropathy, Kidney Transplant Recipients
MYTP01 for Immune-Mediated Diseases
The goal of this study is to evaluate whether MYTP01, a traditional Chinese herbal formula developed by clinical experts with the assistance of artificial intelligence (AI), is effective and safe as an additional treatment for…
- Conditions
- IgA Nephropathy, Kidney Transplant Recipients, Lupus Nephritis, Primary Membranous Nephropathy
- Trial name
- NCT07901764
- Testing
- MYTP01
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Zhejiang Provincial People's Hospital
Thyroid Eye Disease, TED, Graves Orbitopathy
Study to Assess Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED)
The goal of this clinical trial is to evaluate the efficacy, safety, and tolerability of linsitinib in participants with moderate to severe Thyroid Eye Disease (TED).
- Trial name
- ORBIT (NCT07753603)
- Testing
- linsitinib
- Where
- 18 sites in United States
- Volunteers
- 130 people
- Sponsor
- Sling Therapeutics, Inc.
Thyroid Autoimmune Disease, Hashimoto's Thyroiditis
Impact of Restrictive Diets on Inflammation and Quality of Life in Autoimmune Thyroiditis
The purpose of this clinical trial is to evaluate whether a dietary intervention can improve clinical and immunological outcomes in women with autoimmune thyroid disease (AITD), including Hashimoto's thyroiditis and Graves'…
- Conditions
- Thyroid Autoimmune Disease, Hashimoto's Thyroiditis, Graves Disease
- Trial name
- TAILOR (NCT07879690)
- Testing
- Gluten-free, casein-free, low-glycemic-index diet
- Where
- Andorra
- Volunteers
- 60 people
- Sponsor
- University of Barcelona
Hashimoto Thyroiditis, Mediterranean Diet
The Impact of Change of Thyroid Antibodies on Hormone Level and Disease Burden in Patients With Hashimoto's Thyroiditis
Hashimoto's thyroiditis (HT) is an autoimmune disease affecting the thyroid gland and is one of the most common causes of hypothyroidism. Eating habits may affect the risk of several inflammatory and immune diseases, such as HT.
- Trial name
- Anti-TPO/TG (NCT07048821)
- Testing
- Dietary modification
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sherihan AboElyazed Mohamed Khalil
Hashimoto Thyroiditis, Goiter
Role of Total Thyroidectomy in Relieving Local Symptoms in Hashimoto's Thyroiditis
This study aims to evaluate the role and effectiveness of total thyroidectomy in relieving compressive and local symptoms (such as dysphagia, dyspnea, and anterior neck pain/discomfort) in patients with Hashimoto's thyroiditis…
- Trial name
- NCT07852026
- Testing
- Total Thyroidectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Hypothyroidism, Hashimoto Disease
Gluten Free Diet in Hashimoto's Hypothyroidism
Hashimoto's thyroiditis is an autoimmune condition that reduces functioning of the thyroid gland and can lead to a substantial decline in quality of life for patients, with impacted patients often describing unremitting brain…
- Trial name
- NCT07060118
- Testing
- Gluten Free Diet in Hashimoto's Hypothyroidism
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
Thyroid Eye Disease, Graves Orbitopathy
A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)
The overall objective is to study the safety, pharmacokinetics and efficacy of linsitinib (a small molecule IGF-1R inhibitor) administered orally twice daily (BID) vs.
- Conditions
- Thyroid Eye Disease, Graves Orbitopathy, Endocrine System Diseases, Eye Diseases
- Trial name
- LIDS (NCT05276063)
- Testing
- Linsitinib
- Where
- 30 sites in United States, Canada and 3 more
- Volunteers
- 90 people
- Sponsor
- Sling Therapeutics, Inc.
Thyroid Disease, Autoimmune Hepatitis
Thyroid Disorders in Pediatric Autoimmune Hepatitis
This cross-sectional study aims to determine the frequency and spectrum of thyroid disorders among children with autoimmune hepatitis attending Assiut University Children's Hospital.
- Conditions
- Thyroid Disease, Autoimmune Hepatitis, Hashimoto Thyroiditis, Graves Disease
- Trial name
- NCT07827235
- Volunteers
- 32 people
- Sponsor
- Assiut University
Papillary Thyroid Cancer, Hashimoto Disease
Incidental Thyroid Cancer in Cases With Inflammatory Thyroid Lesion
This study aim to assess for the incidence of thyroid cancer in patients with autoimmune thyroiditis (Inflammatory thyroid Lesions)
- Conditions
- Papillary Thyroid Cancer, Hashimoto Disease, Hashimoto's Thyroiditis, Follicular Thyroid Cancer
- Trial name
- Thyroid cancer (NCT07652450)
- Testing
- total thyroidectomy
- Where
- Egypt
- Volunteers
- 98 people
- Sponsor
- Minia University
Graves Disease, Hashimoto Disease
Preoperative Corticosteroids in Autoimmune Thyroid Disease
This study proposes to randomize patients about to undergo surgery for their autoimmune, inflammatory thyroid disease, and determine if a short course of corticosteroids decreases the inflammation of the gland and makes surgery…
- Trial name
- NCT05435547
- Testing
- Dexamethasone
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- Indiana University
Type 1 Diabetes, Hashimoto Disease
Telehealth Music Therapy for Adults With Endocrine Disorder and Depression
The goal of this clinical trial is to explore if a telehealth music therapy intervention helps with quality of life, depression symptoms, anxiety symptoms. It will also explore the participants' relationship to music.
- Conditions
- Type 1 Diabetes, Hashimoto Disease, Graves Disease, Addison Disease
- Trial name
- NCT07413874
- Testing
- Telehealth Resource Oriented Music Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Appalachian State University
Hashimoto Thyroiditis, Subacute Thyroiditis
Colchicine for Autoimmune and Subacute Thyroiditis
Thyroiditis includes inflammatory thyroid disorders such as Hashimoto's thyroiditis and subacute thyroiditis. These conditions may cause thyroid pain, neck tenderness, elevated inflammatory markers, thyroid dysfunction, fatigue…
- Conditions
- Hashimoto Thyroiditis, Subacute Thyroiditis, Thyroiditis
- Trial name
- COLTHYR (NCT07571681)
- Testing
- colchicine, Prednisolone, NSAID
- Where
- 2 sites in Egypt, Saudi Arabia
- Volunteers
- 300 people
- Sponsor
- Mansoura University
Thyroid Disease, Hashimoto's Thyroiditis
ThyMoves: Screening and Exercise to Improve Muscle, Enhance Quality of Life, and Reduce Fall Risk in Thyroid Disease
Objectives: This study aims to assess health-related quality of life (QoL) in adults with thyroid hormone disorders and identify modifiable factors to improve QoL in patients with Hashimoto's thyroiditis (HT) and multinodular…
- Conditions
- Thyroid Disease, Hashimoto's Thyroiditis, Hyperthyreosis and Goiter, Hypothyroidism
- Trial name
- ThyMoves (NCT06960005)
- Testing
- Rhythm- and Multitask-Based Activity (RYMA) and Activities of Daily Living (ADL)
- Where
- Denmark
- Volunteers
- 148 people
- Sponsor
- Aalborg University Hospital
Hashimoto Thyroiditis
rT3 and Inflammation in Hashimoto's Thyroiditis
Hashimoto's thyroiditis (HT) is characterized by an enlarged thyroid gland infiltrated with lymphocytes. The incidence of HT is estimated to be 0.3-1.5 cases per 1000 people, with a female/male predominance of 7-10:1.
- Trial name
- NCT07510750
- Where
- Turkey (Türkiye)
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Autoimmune Thyroiditis
Dysregulation of the Soluble α-Klotho-FGF23 Axis in Hashimoto's Thyroiditis: A Case-Control Study
Hashimoto's thyroiditis (HT) is the most common autoimmune thyroid disease and is increasingly recognized as a condition associated with chronic low-grade systemic inflammation beyond thyroid hormone dysfunction.
- Trial name
- klofgfhashi (NCT07453290)
- Testing
- Blood Sampling and Biomarker Measurement
- Volunteers
- 150 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Thyroid Eye Disease, Graves Orbitopathy
Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)
The overall study objective is to continue to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of linsitinib in subjects who were enrolled in the prior VGN-TED-301 through Week 24.
- Conditions
- Thyroid Eye Disease, Graves Orbitopathy, Endocrine System Diseases, Eye Diseases
- Trial name
- NCT06112340
- Testing
- linsitinib
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Sling Therapeutics, Inc.
Hashimoto Thyroiditis, Thyroiditis
Effect of Photobiomodulation Therapy in Patients With Hashimoto's Thyroiditis
The standard lifelong treatment for Hashimoto's thyroiditis (HT), a chronic autoimmune disease, is levothyroxine (LT4) therapy. Despite LT4 replacement therapy, patients continue to experience persistent fatigue, deterioration in…
- Trial name
- NCT06735040
- Testing
- Photobiomodulation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Optic Neuritis, Transverse Myelitis
Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)
The Swiss-Ped-IBrainD is a national patient registry that collects information on diagnosis, symptoms, treatment, and follow-up of pediatric patients with an inflammatory brain disease in Switzerland.
- Conditions
- Optic Neuritis, Transverse Myelitis, Acute Disseminated Encephalomyelitis, Multiple Sclerosis
- Trial name
- NCT05017142
- Where
- 13 sites in Switzerland
- Volunteers
- 500 people
- Sponsor
- University of Bern
Hashimoto Thyroiditis, Autoimmune Thyroiditis
Effects of Low-Level Laser Therapy on Oxidative Stress Levels
Hashimoto's thyroiditis (HT) is the most commonly observed inflammatory and autoimmune disease of the thyroid gland. Recent evidence has suggested that low-level laser therapy (LLLT) can improve thyroid function and reduce levels…
- Conditions
- Hashimoto Thyroiditis, Autoimmune Thyroiditis, Thyroiditis, Thyroid Diseases
- Trial name
- NCT04754607
- Testing
- Low Level Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Istanbul Medipol University Hospital
Hashimoto's Thyroiditis
Hashimoto's Thyroiditis in Upper Egypt
The aim of this study is to evaluate the pathological pattern, characteristic features, treatment, complications and prognosis of Hashimoto's thyroiditis in upper Egypt.
- Trial name
- NCT06603415
- Testing
- Total thyroidectomy
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University