Clinical trials: Head and Neck Lymphedema
Cancer Survivor, Head and Neck Cancer
Impact of Secondary Lymphedema on Symptoms, Functional Status, and Quality of Life After Treatment in Patients With Head and Neck Cancer
RATIONALE: Collecting information about the impact of lymphedema on symptoms, functional status, and quality of life after treatment in patients with head and neck cancer may help doctors learn more about the disease and plan the…
- Conditions
- Cancer Survivor, Head and Neck Cancer, Lymphedema
- Trial name
- NCT01098669
- Where
- 2 sites in United States
- Volunteers
- 103 people
- Sponsor
- Vanderbilt University
Head and Neck Lymphedema
Determining Swallow Outcomes in Head & Neck Lymphedema Subjects Receiving Early Intervention With Pneumatic Compression
The objective of the study is to assess the effect early pneumatic compression (prior to confirming cancer-free status via PET or CT imaging) has on swallow outcomes, positron emission tomography (PET) measurements, function, and…
- Trial name
- NCT04335981
- Testing
- FT-CC and Swallow Exercises, Swallow Exercises
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Tactile Medical
Lymphedema of Face, Head and Neck Cancer
Assessing Impact of Early Physiotherapy on Lymphatic Dysfunction in Head and Neck Cancer Survivorship
The goal of this clinical trial is to learn if treating the lymphatics in head and neck cancer survivors before clinical diagnosis of lymphedema will prevent its development or progression.
- Trial name
- NCT05937269
- Testing
- Near-infrared fluorescence lymphatic imaging, advanced pneumatic compression therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The University of Texas Health Science Center, Houston
Head and Neck Cancer, Lymphedema
Home-Based Lymphedema Care Program (HBLCP) in Improving Lymphedema Self-Care in Head and Neck Cancer Survivors
This pilot clinical trial studies a home-based lymphedema care program in improving lymphedema self-care in head and neck cancer survivors.
- Trial name
- NCT02170272
- Testing
- Home-based Lymphedema Care Program
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Head and Neck Cancer, Lymphedema
Comparing Two Ways to Manage Head and Neck Lymphedema
This randomized clinical trial aims to compare clinic-based CDT and home-based (a hybrid model) CDT on changes in the severity of lymphedema, symptom burden, functional status, and healthcare utilization in HNC survivors with…
- Trial name
- NCT05182229
- Testing
- Home-based (a hybrid model) CDT, Clinic-based CDT
- Where
- 6 sites in United States
- Volunteers
- 240 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Lymphedema, Head and Neck Cancer
The Efficacy of Kinesio Taping on Lymphedema Following Head and Neck Cancer Therapy
Purpose off the study is investigating to efficacy of kinesio taping on neck lymphedema after the head and neck cancer therapy.
- Conditions
- Lymphedema, Head and Neck Cancer, Kinesio Taping, Therapy
- Trial name
- NCT04691310
- Testing
- Kinesio Tex Gold
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Lymphedema, Lymphedema of Face
Clinical Lymphedema Evaluation - Advancing Reconstruction of Head and Neck Lymphatics With Symani
The objective of this study is to evaluate the Symani System's safety and effectiveness for microsurgical anastomosis during open lymphatic reconstruction in the head and neck.
- Conditions
- Lymphedema, Lymphedema of Face, Internal Lymphedema, External Lymphedema
- Trial name
- CLEAR (NCT07311876)
- Testing
- Symani Surgical System
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- MMI (Medical Microinstruments, Inc.)
Lymphedema, Secondary
Skin Biophysical Measures for Assessing Head and Neck Cancer-Related External Lymphedema
Selected measurements in healthy persons of skin tissue dielectric constant as reference values for subsequent use to evaluate patients with head and neck lymphedema.
- Trial name
- NCT04457375
- Testing
- TDC
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Head and Neck Cancer, Lymphedema of Face
Two Different Physiotherapy Programs in Lymphedema Following Head and Neck Cancer Treatment
The aim of this study was to determine the effects of complex decongestive physiotherapy (CDP) and home programs on internal/external lymphedema, staging, fibrosis, and three-dimensional (3D) surface scanning and volume…
- Conditions
- Head and Neck Cancer, Lymphedema of Face, Fibrosis; Skin
- Trial name
- NCT04286698
- Testing
- Complex decongestive physiotherapy, Home program
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Izmir Bakircay University
Head and Neck Lymphedema
A Registry to Evaluate the Flexitouch System and Flexitouch Plus for Treatment of Head and Neck Lymphedema
The objective of this registry is to evaluate the long term effectiveness of the Flexitouch System and Flexitouch Plus in those with head and neck lymphedema.
- Trial name
- NCT03558672
- Testing
- Flexitouch system with Head and Neck Garments
- Where
- 4 sites in United States
- Volunteers
- 18 people
- Sponsor
- Tactile Medical
Head and Neck Cancer, Lymphedema of the Head and Neck
Photobiomodulation in Head and Neck Cancer-Related Chronic Lymphedema
The U.S. Food and Drug Administration approved photobiomodulation therapy (PBMT) as a treatment for breast cancer-related arm lymphedema (BCRL) in 2006. The investigators conducted two pilot clinical trials.
- Trial name
- NCT06837480
- Testing
- LTU-904 Portable Laser Therapy Unit (active laser device)
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Head and Neck Cancer
Effects of a Home-Based Exercise Program During Radiotherapy
The purpose of this study is to examine the effects of exercise on individuals with head and neck cancer who are receiving postoperative radiotherapy. The study is based on three primary hypotheses: 1.
- Trial name
- NCT07376213
- Testing
- Home-based exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Burak Ertürk
Head and Neck Cancer, Lymphedema
Low-Level Laser in Treatment of Head and Neck Lymphedema: A Pilot Study
The purpose of this pilot clinical trial is to evaluate the feasibility of the use of low-level laser for head and neck cancer survivors with lymphedema.
- Conditions
- Head and Neck Cancer, Lymphedema, Fibrosis
- Trial name
- NCT03738332
- Testing
- Low-Level Laser
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Pennsylvania
Head and Neck Neoplasms, Head and Neck Cancer
A Pilot Study to Evaluate the Feasibility and Potential Effectiveness of the Flexitouch System Head and Neck Treatment
The study will evaluate the feasibility and potential effectiveness of the Flexitouch head and neck treatment plus standard home care compared to standard home care regimen alone.
- Conditions
- Head and Neck Neoplasms, Head and Neck Cancer, Head and Neck Lymphedema
- Trial name
- NCT03332160
- Testing
- Flexitouch head and neck lymphedema treatment system, Standard home lymphedema care
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- Tactile Medical
Lymphedema, Oropharyngeal Cancer
Complete Decongestive Therapy (CDT) for Treatment of Head and Neck Lymphedema
Objectives: Specific Aim 1: Estimate the prevalence of head and neck lymphedema in patients who have been treated with surgery and/or radiation therapy (± chemotherapy) for oral cavity and oropharyngeal cancer.
- Conditions
- Lymphedema, Oropharyngeal Cancer, Head and Neck Cancer, Oral Cancer
- Trial name
- NCT00951470
- Testing
- Follow -Up Visits, Full CDT, Modified CDT Program
- Sponsor
- M.D. Anderson Cancer Center
Fibrosis Syndrome, Lymphedema
Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)
To find out if adding medication can help treat or prevent lymphedema and/or fibrosis related to radiation therapy, in survivors of head and neck cancer.
- Conditions
- Fibrosis Syndrome, Lymphedema, Head &Amp; Neck Cancer, Fibrosis
- Trial name
- NCT06912763
- Testing
- Pravastatin (drug), Pentoxifylline, ketoprofen
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- M.D. Anderson Cancer Center
Lymphedema of Face, Neoplasms
Manual Lymph Drainage for External Lymphedema
This study will evaluate the feasibility of a randomized controlled trial. The future randomized controlled trial will compare two groups following different intensities of manual lymphatic drainage for external head- and neck…
- Conditions
- Lymphedema of Face, Neoplasms, Radiotherapy Side Effect, Lymphedema Due to Radiation
- Trial name
- MLD-HN (NCT07215169)
- Testing
- HIT, LIT
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Lund University
Head and Neck Neoplasms, Head and Neck Lymphedema
Response to Intermittent Pneumatic Compression Therapy in Head and Neck Cancer-Related Lymphedema
Assessment of lymphatic structure and function pre- and post- treatment and during recovery in head and neck cancer related lymphedema patients using NIR fluorescence lymphatic imaging: Response to ICD therapy in HNC Patients.
- Conditions
- Head and Neck Neoplasms, Head and Neck Lymphedema, Head and Neck Cancer
- Trial name
- NCT02946021
- Testing
- Head and neck garments for pneumatic compression device, NIRFLI with ICG
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Tactile Medical