Clinical trials: Headache Disorder
Headache, Migraine
PGI2 Induced Headache and Cerebral Haemodynamics in Healthy Volunteers
Before , during and after intravenous administration of PGI2 we score/measure headache, rCBF, blood flow in middle cerebral artery and diameter of superficial temporal artery/radial artery and correlate that to known…
- Trial name
- NCT00291395
- Testing
- PGI2
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Cervicogenic Headache
Is Chiropractic Spinal Manipulative Therapy an Efficient Treatment Option in Cervicogenic Headache
This study will highlight and validate chiropractic spinal manipulative therapy (CSMT) for cervicogenic headache (CEH). If the method proves to be effective, it will provide a new non-pharmacological treatment option for CEH.
- Trial name
- NCT01687881
- Testing
- Chiropractic
- Where
- Norway
- Volunteers
- 19 people
- Sponsor
- University Hospital, Akershus
Migraine, Headache
Amitriptyline vs GON and SON Blocks in Migraine
Comparison of efficacy and safety of amitriptyline and nerve blocks
- Trial name
- NCT04750967
- Testing
- Lidocaine 1% Injectable Solution, Amitriptyline
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Migraine
Long-term Safety and Tolerability of Subcutaneous Administration of TEV-48125 for the Preventive Treatment of Migraine
To evaluate the long-term safety and tolerability of subcutaneous (SC) administration of TEV-48125 (at 225 mg once monthly [except for a loading dose of 675 mg for CM patients] or at 675 mg every 3 months) for the preventive…
- Trial name
- NCT03303105
- Testing
- TEV-48125
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Post Traumatic Headache, Cervicogenic Headache
Comparative Effects of Post Isometric Relaxation and Reciprocal Inhibition in Individuals With Cervicogenic Headache.
This study aims to compare the effects of Post Isometric Relaxation (PIR) and Reciprocal Inhibition (RI) in individuals with cervicogenic headache, a secondary headache originating from dysfunction of the cervical spine…
- Trial name
- NCT07838545
- Testing
- Post Isometric Relaxation, Reciprocal Inhibition
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Foundation University Islamabad
Chronic Migraine
Prophylactic Treatment With Atorvastatin for Chronic Migraine (ChronicStatinMig)
The main objective of this study is to see whether the favorable preventative effect of Atorvastatin 40mg per day in episodic migraine, that was found previously in three smaller randomized controlled cross-over studies, can be…
- Trial name
- NCT06485336
- Testing
- Atorvastatin 40mg
- Where
- 6 sites in Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Chronic Headache, Migraine
Assessment of the Effectiveness of Virtual Reality as a Learning Tool for Relaxation Techniques in Reducing Pediatric Migraines and Tension Type Headache
The goal of this interventional study is to assess the efficacy of a therapeutic intervention aimed at diminishing pediatric chronic headache.
- Conditions
- Chronic Headache, Migraine, Tension Type Headache
- Trial name
- NCT06921109
- Testing
- Experimental: Relaxation training with VR, Experimental: Relaxation training without VR, No Intervention: Control group
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University of Liege
Migraine, Migraine Disorders
Habituation of the Nociceptive Blink Reflex in Experimentally Induced Migraine Attack
People with migraine typically show impaired responsivity to visual, auditory and pain stimuli (Burstein et al, 2015). The electrophysiological study of the nociceptive blink reflex (nBR) is widely adopted for the instrumental…
- Conditions
- Migraine, Migraine Disorders, Pain
- Trial name
- NCT05718310
- Testing
- Nitroglycerin, Saline
- Where
- 2 sites in Italy
- Volunteers
- 22 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Migraine Headache
Study in Participants With Acute Migraines Headaches
This is a Phase 2, multicenter, randomized, double-blind, placebo and active comparator-controlled study of LY2590443 in approximately 200 participants with migraines.
- Trial name
- NCT00804973
- Testing
- LY2590443, Sumatriptan
- Where
- 19 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Postdural Puncture Headache
Lumbar Spine Ultrasound of Patients With Previous Accidental Dural Puncture During Labour Epidural
Accidental dural puncture is a potential complication of epidural analgesia for labour and delivery. When it happens, it may cause debilitating headaches and other symptoms that prevent mothers from talking care of their…
- Trial name
- NCT00465166
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Migraine
Pilot Study to Compare Frovatriptan vs. Topiramate for Prevention of Migraine
Subjects enrolled at 2 investigative sites will complete 3 visits. Following Visit 1, during a 1-month Baseline Period, subjects will treat with their usual medication and document any warning signs (Prodrome pre-headache) that a…
- Trial name
- NCT00846495
- Testing
- topiramate, frovatriptan
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Clinvest
Depression, Migraine
Vortioxetine in Depression and Concomitant Migraine
Depression and migraine are among the most prevalent conditions in the general population, and many research shows they are closely related.
- Trial name
- VORTIX (NCT07579481)
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cervicogenic Headache, Cervicogenic Headaches
Comparison of Myofascial Release and Mulligan Concept Techniques in Patients With Cervicogenic Headache
The International Headache Society classifies cervicogenic headache as a secondary headache caused by a disorder of the cervical spine and its components.
- Trial name
- NCT06690411
- Testing
- Mulligan Concept, Myofascial Release Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medipol University Hospital
Migraine Disorders, Migraine
Prevention Study in Adult Patients Suffering From Migraine Headaches
Purpose of the study is to evaluate dose response relationship, efficacy, safety and tolerability of target doses of GSK1838262 compared to placebo in the prophylactic treatment of migraine headache.
- Trial name
- NCT00742209
- Testing
- GSK1838262
- Where
- 59 sites in United States, Canada
- Volunteers
- 526 people
- Sponsor
- XenoPort, Inc.
Headache (Migraine)
Work-related Burden Changes, Quantified with HEADWORK, Among Individuals Treated with Migraine Preventive Therapies.
Migraine is one of the leading causes of disability worldwide among the population under 50. It's economic indirect burden is mostly determined by reduction of work productivity both by absenteeism and presenteeism.
- Trial name
- NCT06812299
- Where
- 3 sites in Italy
- Volunteers
- 175 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Migraine
AI Chatbot for Migraine Management in Hong Kong Women
The goal of this randomized crossover trial is to examine whether the AI-empowered chatbot will effectively collect comprehensive migraine feature data and demonstrate higher compliance, accuracy, utilization, acceptability…
- Trial name
- NCT06920602
- Testing
- AI-empowered voice-interactive chatbot, Paper migraine diary
- Where
- Hong Kong
- Volunteers
- 49 people
- Sponsor
- The Hong Kong Polytechnic University
Migraine, Medication Overuse Headache
A Study of Eptinezumab in Participants With Migraine and Medication Overuse Headache
Medication overuse headache (MOH) is a type of headache caused by excessive use of acute headache or migraine medications (medications used to treat a headache or migraine once it begins).
- Trial name
- RESOLUTION (NCT05452239)
- Testing
- Eptinezumab
- Where
- 76 sites in United States, Australia and 9 more
- Volunteers
- 608 people
- Sponsor
- H. Lundbeck A/S
Headache, Migraine
Investigating the Frequency and Phenotype of Headaches Associated With Fasting During the Month of Ramadan.
Headaches are more common in the month of Ramadan in patients who already suffer from migraine. The object of the present study is investigate the frequency in the Ramadan month .
- Trial name
- NCT04804995
- Testing
- There is no intervention.
- Where
- Denmark
- Volunteers
- 134 people
- Sponsor
- Danish Headache Center
Migraine, Depressive Symptoms
Treatment for Migraine and Mood
The researchers propose a three-arm pilot study of Mindfulness-Based Cognitive Therapy (MBCT) delivered via telephone (MBCT-T), video (MBCT-V) or Enhanced Usual Care (EUC).
- Trial name
- TEAM-M (NCT05576467)
- Testing
- MBCT-Telephone, MBCT-Video, Enhanced Usual Care (EUC)
- Where
- 3 sites in United States
- Volunteers
- 145 people
- Sponsor
- Amanda Shallcross
Migraine With Aura, Migraine Without Aura
Evaluation of the Efficacy of Almotriptan and Ubrogepant for the Acute Treatment of Migraine
In a real-world population of adults with migraine, the investigators would like to investigate whether 12.5 mg almotriptan is non-inferior to 50 mg ubrogepant in terms of pain freedom at 2 hours after drug intake.
- Trial name
- ATOM (NCT05214001)
- Testing
- Almotriptan 12.5 Mg Oral Tablet, Ubrogepant 50Mg Tab
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Messoud Ashina, MD
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.