Clinical trials: Headache Disorder
Migraine
Study of Pregnancy Outcomes in Women Exposed to Rimegepant During Pregnancy
The purpose of the study is to evaluate the risk of pregnancy and infant outcomes among women with migraine exposed to rimegepant during pregnancy and in two rimegepant unexposed comparator groups.
- Trial name
- NCT05198245
- Testing
- Rimegepant, Various, No intervention
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Pfizer
Neck Pain
Investigation of Related Factors in Patients With Non-Specific Neck Pain
It has been shown that there is a complex association between neck pain, temporomandibular joint dysfunctions, and migraines, and that these conditions can be influenced by factors such as depression, physical inactivity, and…
- Trial name
- NCT06889220
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Hacettepe University
Depression, Anxiety
The Effect of Psychological State on Post Spinal Puncture Headache and Backache
To investigate the effect of patient mood before spinal anesthesia on post spinal puncture headache and backache
- Trial name
- NCT03427372
- Testing
- anxiety scale, depression scale
- Where
- Turkey (Türkiye)
- Volunteers
- 370 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Low Back Pain, Migraine
Evaluating the Safety and Tolerability of OraVescent Fentanyl for Opioid Tolerant Patients With Noncancer Related Breakthrough Pain
The purpose of this study is to evaluate the safety and tolerability of OraVescent fentanyl for the potential treatment of breakthrough pain episodes in patients who have chronic noncancer pain.
- Conditions
- Low Back Pain, Migraine, Diabetic Neuropathies, Osteoarthritis
- Trial name
- NCT00228605
- Testing
- OraVescent Fentanyl
- Where
- 38 sites in United States
- Volunteers
- 500 people
- Sponsor
- Cephalon
Migraine
Optical Treatment of Migraines Using the Avulux™ Optical Filter in the Form of Spectacle Lenses.
The primary objective of this study is to evaluate the efficacy of the Avulux device in reducing the impact of migraine headaches as measured by improvement in Headache Impact Test (HIT-6TM) scores at three weeks when compared to…
- Trial name
- NCT03902496
- Testing
- HIT-6 Questionnaire, Avulux Spectacles
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Avulux, Inc.
Migraine
Randomized Controlled Trial of Treating Migraine With Acupuncture
The purpose of the study is to testify whether acupuncture is effective for migraine, and provide evidence for the hypothesis that"Acupuncture effect is based on meridians, and gathering of meridian Qi is the key point."
- Trial name
- NCT00599586
- Testing
- acupuncture
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Headache, Pituitary Tumor
The TMS Treatment for Postoperative Headache in GH Tumor
Headache is a very common main complaint of patients with GH pituitary tumor, which has seriously affected the normal work and life of patients.
- Conditions
- Headache, Pituitary Tumor, Acromegaly
- Trial name
- NCT04529356
- Testing
- Transcranial magnetic stimulation, Acetaminophen
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Migraine Disorders
Effects of the Visual Stimulation on the Motor and Visual Cortex in Migraneurs With and Without Aura
The aim of this study is to investigate the motor and visual cortex excitability in response to visual stimulation of migraineurs with and without aura compared to healthy individuals.
- Trial name
- NCT02564822
- Testing
- Visual Stimulation
- Where
- Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Headache, Migraine
Effect of Transmagnetic Stimulation on Conditioned Pain Modulation (CPM)
While some indications of the neural circuits involved in the Conditioned Pain Modulation (CPM) process are now available, there is still need to clarify what parts of the brain are essential for this process, whether the…
- Trial name
- NCT01501045
- Testing
- TMS system MagPro x100, Tonica Elektronik A/S, Denmark
- Where
- Israel
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Episodic Cluster Headache
Intranasal Civamide for Episodic Cluster Headache
This is a 49-day study to evaluate the effectiveness of Intranasal Civamide (Zucapsaicin) in the treatment of an episodic cluster headache period compared to placebo (medically inactive substance which does not contain any active…
- Trial name
- NCT00069082
- Testing
- Civamide (Zucapsaicin), Sodium Chloride
- Where
- 6 sites in United States
- Volunteers
- 2 people
- Sponsor
- Winston Laboratories
Migraine
Coping Skills for Migraine: A 6-Month Program
This study aimed to investigate the effects of client-centered coping skills training on pain, quality of life, disability level, and coping skills in individuals with migraine over a 6-month follow-up period.
- Trial name
- NCT07163559
- Testing
- coping skills training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Cervicogenic Headache
Impact of Adding Integrated Neuromuscular Inhibition Technique to Postural Correction Exercises in Patients With Cervicogenic Headache
this study will be conducted to investigate the impact of adding integrated neuromuscular inhibition technique to postural correction exercises in patients with cervicogenic headache
- Trial name
- CGH (NCT07086898)
- Testing
- Integrated Neuromuscular Inhibition Technique, Postural Correction Exercise
- Volunteers
- 90 people
- Sponsor
- Cairo University
Migraine
Effect of Erenumab-aooe on Disability and Work Productivity in Employed Subjects With Episodic Migraine
To evaluate the effect of erenumab compared to placebo on disability in employed subjects with episodic migraine (EM) who have previously failed 1 or more migraine preventive treatments.
- Trial name
- NCT03912337
- Testing
- Erenumab
- Where
- 28 sites in United States
- Volunteers
- 29 people
- Sponsor
- Amgen
Multiple Sclerosis, Alzheimer Disease
Optical Coherence Tomography in Neurological Practice: Utility and Applicability Across Neurological Diseases (OCt.IN.N)
OCt.IN.N is a national, monocentric, prospective, observational cohort study evaluating the utility and applicability of Optical Coherence Tomography (OCT) in the diagnostic workup and longitudinal monitoring of neurological…
- Conditions
- Multiple Sclerosis, Alzheimer Disease, Parkinson Disease, Migraine
- Trial name
- OCT (NCT07720765)
- Testing
- Optical Coherence Tomography (OCT) - Heidelberg SPECTRALIS HRA+OCT
- Where
- Italy
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Migraine, With or Without Aura
Efficacy and Safety of BR005-036C Tablets for the Acute Treatment of Migraine in Adults
The purpose of this study is to compare the efficacy and safety of BR005-036C versus placebo in subjects with Acute Migraines
- Trial name
- NCT07792681
- Testing
- BR005-036C
- Where
- 83 sites in China
- Volunteers
- 2,079 people
- Sponsor
- Brise Pharmaceuticals Co., Ltd.
Migraine
Efficacy and Tolerability of Rimegepant for the Acute Treatment of Migraine in Adults Unsuitable for Triptan Use
This study is being conducted to evaluate the efficacy and tolerability of rimegepant in a population of adults that are unsuitable for triptan medications due to a previous intolerance, lack of efficacy, or contraindication…
- Trial name
- NCT05509400
- Testing
- Rimegepant
- Where
- 93 sites in United States, Australia and 13 more
- Volunteers
- 813 people
- Sponsor
- Pfizer
Migraine Disorders
Phase 3 Study of MAP0004 in Adult Migraineurs
This is a randomized, double blind, placebo controlled, parallel group study of MAP0004 in adult migraineurs. Subjects will self administer study drug in the outpatient setting.
- Trial name
- FREEDOM301 (NCT00623636)
- Testing
- MAP0004
- Where
- United States
- Volunteers
- 902 people
- Sponsor
- Allergan
Idiopathic Intracranial Hypertension
Idiopathic Intracranial Hypertension Treatment Trial
Idiopathic intracranial hypertension (IIH), also called pseudotumor cerebri, is a disorder of elevated intracranial pressure of unknown cause [Corbett, et al., 1982; Wall, et al., 1991].
- Trial name
- IIHTT (NCT01003639)
- Testing
- Acetazolamide, Formal weight loss counselling program
- Where
- 41 sites in United States, Canada
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Migraine
Status Migrainosus - Differentiating Between Responders and Non-responders
The main goal of this study is to determine whether it is possible - in the setup of routine clinical care - to identify in individual patients who are clear responders to drug X, common denominators that are absent in individual…
- Trial name
- NCT03066544
- Testing
- Bupivacaine, Naratriptan Pill, Dexamethasone
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Hartford HealthCare
Temporomandibular Disorders, Headache
Temporomandibular Dysfunction Affects Neck Disability, Headache, Anxiety, And Sleep Quality In Women: A Cross-Sectional Study
The temporomandibular joint (TMJ), is the only movable joint between the joints in the head and neck system. It is a component of the chewing system and is involved in important functions such as speech, swallowing, taste and…
- Conditions
- Temporomandibular Disorders, Headache, Neck Disorder, Anxiety
- Trial name
- NCT04948320
- Where
- Turkey (Türkiye)
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University