Clinical trials: Healing of Extraction Socket
Bio-Oss; Mucograft
Bone Volume Changes After Socket Preservation Using Geistlich Bio-Oss Collagen and Mucograft Seal
Evaluation of Bone volume Changes after socket preservation using Geistlich Bio-Oss® Collagen and Geistlich Mucograft® Seal compared to natural healing after tooth extraction
- Trial name
- NCT03395145
- Testing
- Geistlich Bio-Oss® Collagen and Geistlich Mucograft® Seal
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Healing of Extraction Socket
The Impact of a Known Bioactive Agent on the Resolution of Alveolar Socket Preservation
The advent of endosseous implant restoration has driven an increasing need for alveolar bone preservation and/or augmentation strategies.
- Trial name
- NCT02802436
- Testing
- Extraction with socket graft
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston University
Healing Surgical Wounds, Pain
L-PRF vs PBM on Extraction Socket Healing
The aim of this study is to compare leukocyte and platelet-rich fibrin (L-PRF) and photobiomodulation (PBM) applications, which have been repeatedly reported to be superior to control groups, in terms of pain, soft tissue and…
- Trial name
- NCT06328413
- Testing
- photobiomodulation, Leukocyte and Platelet Rich Fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Molar, Third, Temporomandibular Joint Disorders
Evaluation the Effect of Coenzyme Q10 on Tissue Healing Process in Patients Undergoing Wisdom Tooth Extraction
The goal of this clinical trial is to asses the effect of Coenzyme Q10 administration in patients from any gender group who are older than 18 years old undergoing wisdom tooth extraction.
- Conditions
- Molar, Third, Temporomandibular Joint Disorders, Dry Socket, Coenzyme Q10
- Trial name
- NCT06452134
- Testing
- Coenzyme Q10 100 MG Oral Tablet
- Volunteers
- 70 people
- Sponsor
- Zahra Nejati
Post-surgical Oral Wounds, Oral Cavity Surgery
Evaluation of the Performance and Safety of a Linear Hyaluronic Acid-Based Medical Device in the Treatment of Surgical Wounds in the Oral Cavity.
The PR-DENT study is an interventional, single-center, controlled clinical investigation aimed at evaluating the clinical performance and safety of a Class III medical device based on linear hyaluronic acid for the treatment of…
- Conditions
- Post-surgical Oral Wounds, Oral Cavity Surgery, Wound Healing/Regeneration, Dental Extraction Sites
- Trial name
- PR-DENT (NCT07421934)
- Testing
- Intervention: Linear Hyaluronic Acid (Gumblast), Control: Standard Surgical Procedure
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- The Wave Innovation Group s.r.l.
Medication-related Osteonecrosis of the Jaw
Autologous Platelet Concentrates on the Healing of Extraction Sockets
This study will evaluate the effect of A-PRF, a second-generation APC, on early wound healing in high-risk MRONJ patients following dental extractions, utilising advanced non-invasive methods to assess and associate molecular and…
- Trial name
- NCT07673848
- Testing
- Application of A-PRF into extraction socket
- Volunteers
- 44 people
- Sponsor
- Queen Mary University of London
Hemostasis, Wound Closure
Effective Hemostasis: An Analysis of Hemostatic Sponges Used in Extraction Procedures
Tooth extraction is a common dental procedure, where hemostasis is crucial for patient recovery. This study evaluates the effectiveness of hemostatic sponges in controlling bleeding and promoting postoperative healing.
- Conditions
- Hemostasis, Wound Closure, Pain, Extraction Socket Healing
- Trial name
- NCT07529106
- Testing
- Hemostatic sponge post tooth extraction
- Where
- Paraguay
- Volunteers
- 30 people
- Sponsor
- Universidad Nacional de Caaguazu
Alveolar Ridge Preservation, Bone Regeneration
Using Different Biomaterials to Preserve Bone After Tooth Extraction
This four-arm randomized controlled clinical trial evaluated the clinical, radiographic, and histological outcomes of different approaches to alveolar ridge preservation following tooth extraction.
- Conditions
- Alveolar Ridge Preservation, Bone Regeneration, Tooth Extraction, Dental Implants
- Trial name
- NCT07394738
- Testing
- Allograft, Autogenous Dentin Graft, Hyaluronic Acid Gel
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Inonu University
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluating The Use of CGF Made Gel in Mandibular Extraction Sites of Lower Impacted 3rd Molars.
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) Gel help improve bone healing and reduce pain after the surgical removal of impacted lower third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07520097)
- Testing
- Concentrated Growth Factor (CGF) Gel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Diseases
The Use of PRF in the Management of Soft Tissue Healing
The present study aimed to evaluate the clinical effect of platelet-rich fibrin to improve epithelialization and decrease postoperative pain in post extraction sockets
- Trial name
- PRF (NCT04212767)
- Testing
- Alveolar socket preservation with Platelet-rich fibrin
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal Fluminense
Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth
To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.
This study will compare commercially available, commonly used mouth rinses (0.12% chlorhexidine (CHX) vs. Ethylenediaminetetraacetic acid (EDTA)) for immediate post-operative and daily antiseptic use after tooth extraction and…
- Trial name
- NCT07191262
- Testing
- 0.12% CHX and Essential Oil mouthrinse, 2.6% EDTA and 0.2% EDTA mouth rinse
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Edentulism
Platelet-Rich Fibrinogen in Extraction Socket Healing of the Aged
The purpose of this study is to better understand oral wound healing in the aged participant following placement of platelet-rich fibrinogen (PRF).
- Trial name
- NCT06943846
- Testing
- Platelet-rich fibrin (PRF)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Nebraska
Tooth Extraction
Combination Therapy Effect of Laser on Wound Healing and Bone Regeneration of Dental Sockets
The goal of this clinical trial is to learn if the laser works to improve wound healing and bone regeneration after tooth extraction.
- Trial name
- NCT06552936
- Testing
- Diode Laser 980 nm.
- Where
- 2 sites in Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sharif Medical Research Center
Bone Healing, Implant Stability
ISQ Differences Between Different Implants in Post-extraction Sockets
Two different implants will be used in post-extraction sockets and ISQ will be recorded monthly from insertion moment to 12 months of follow up to understand if ISQ can be affected by implant macro design
- Trial name
- NCT06711744
- Testing
- Implant stability quotient
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluation of the Use of CGF Based Sticky Bone Packed in Fresh Odontectomy Site of Impacted Lower 3rd Molars
This clinical study aims to evaluate the effectiveness of Concentrated Growth Factor (CGF)-based sticky bone in enhancing bone healing after surgical removal of impacted mandibular third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07517835)
- Testing
- Concentrated growth factors
- Volunteers
- 10 people
- Sponsor
- Cairo University
PRF
Topical Application of PRF Before Radiation Therapy
The primary goal of this study is to observe whether PRP promotes the wound healing before a radiation therapy or not, compared to the natural healing of a tooth extraction socket.
- Trial name
- PRF (NCT06406530)
- Testing
- PRF, Natural Healing
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- University of Giessen
Extraction Socket Healing, Quality of Life
The Effect of Different Types of Mouthwash on Extraction Sockets' Healing
The goal of this clinical trial is to assess the effect of four different types of mouthwash on socket healing after surgical extractions in male or female patients aged 18 years and older who have a unilateral impacted…
- Conditions
- Extraction Socket Healing, Quality of Life, Postoperative Complications
- Trial name
- NCT06587880
- Testing
- Chlorhexidine Gluconate, Bone Bioactive Liquid, Hyaluronic Acid mouthwash
- Where
- Jordan
- Volunteers
- 100 people
- Sponsor
- University of Jordan
Wound Healing, Alveolitis of Jaw
Effect of Curcumin Topical Spray on Wound Healing After Tooth Extraction
This randomized, single-blind, controlled clinical trial aims to evaluate the effects of a topical curcumin spray on post-extraction wound healing and postoperative symptoms in adults undergoing first molar extraction.
- Conditions
- Wound Healing, Alveolitis of Jaw, Tooth Extraction, Curcumin
- Trial name
- NCT07874789
- Testing
- Curcumin Topical Spray, Chlorhexidine Topical Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
TEETH EXTRACTION
Titanium-Prepared Platelet-Rich Fibrin for Extraction Socket Healing
Alveolar ridge preservation after tooth extraction is important for maintaining bone volume and facilitating future implant placement.
- Trial name
- TPRF-SOCKET (NCT07712497)
- Testing
- Titanium-Prepared Platelet-Rich Fibrin (T-PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Eskisehir Osmangazi University
Tooth Extraction, Tooth Extraction Site Healing
Comparison of Intraligamentary Anesthesia With the Inferior Alveolar Nerve Block for the Extraction of Mandibular Molars.
Local anaesthesia or numbing is done before tooth extraction. This study compares two different methods of numbing molar teeth before extraction.
- Trial name
- NCT06611865
- Testing
- Intraligamentary anaesthesia, Inferior alveolar nerve block
- Where
- Pakistan
- Volunteers
- 535 people
- Sponsor
- Hamza Zia Ahmed