Clinical trials: Healing of Extraction Socket
Wisdom Tooth, Socket Preservation
Soft and Hard Tissue Healing Following Alveolar Ridge Preservation of Mandibular Third Molar Extraction Socket Filled With Auto Tooth Bone Graft or Alloplastic Graft
This study compared two bone graft materials: 1. Auto Tooth Bone (ATB) (made from the patient's own extracted tooth) and 2. EthOss® a synthetic alternative.
- Trial name
- AutoToothGraft (NCT07723183)
- Testing
- auto tooth graft material
- Where
- Malaysia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Dry Socket, Postoperative Infections
The Effect of Chlorhexidine + Hyaluronic Acid on Postoperative Wound Healing After Lower Third Molar Removal
Our aim is to evaluate chlorhexidine-hyaluronic acid containing gel on postoperative wound healing regarding impacted lower third molar surgery.
- Trial name
- NCT07044219
- Testing
- Third molar surgery
- Where
- Hungary
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Tooth Extraction
A Volumetric Analysis of Soft and Hard Tissue Healing for Ridge Preservation and Socket Seal After Tooth Extraction
This study will be a randomized clinical trial involving a total of 24 subjects. The investigators propose to recruit subjects into 2 groups: 1) Extraction treated with xenograft bone substitute (BioOss Collagen®) + collagen…
- Trial name
- NCT02844569
- Testing
- Xenograft bone substitute, Collagen dressing, 3D-collagen matrix
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Alveolar Osteitis, Dry Socket
Treatment of Alveolar Osteitis: Traditional or Regenerative?
Alveolar osteitis, commonly referred to as dry socket, is a common painful postoperative complication following tooth extraction.
- Conditions
- Alveolar Osteitis, Dry Socket, Pain, Healing
- Trial name
- NCT05615272
- Testing
- Bio-PRF, Alveogyl
- Where
- Ireland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Alveolar Ridge Preservation, Tooth Loss
Volumetric Efficacy of Alveolar Ridge Preservation
The goal of this clinical trial is to compare the effectiveness of four post-extraction socket management approaches in preserving alveolar ridge dimensions following tooth extraction in adults requiring implant-supported…
- Conditions
- Alveolar Ridge Preservation, Tooth Loss, Tooth Extraction, Tooth Extraction Site Healing
- Trial name
- ARP (NCT07812883)
- Testing
- Spontaneous Healing, d-PTFE Membrane, Leukocyte- and Platelet-Rich Fibrin (L-PRF)
- Where
- Chile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Impacted Mandibular Third Molar, Alveolar Bone Loss
Healing of Mandibular Third Molar Extraction Sockets Using Platelet Concentrates and Photobiomodulation
Surgical removal of impacted mandibular third molars is a common procedure that may be associated with postoperative pain, swelling, limited mouth opening, and delayed bone healing.
- Conditions
- Impacted Mandibular Third Molar, Alveolar Bone Loss, Impacted Mandibular Third Molar Extraction
- Trial name
- NCT07324213
- Testing
- Mandibular Third Molar Extraction With Primary Wound Closure, Autologous Platelet Concentrates, Photobiomodulation
- Where
- Poland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw
Extraction Socket Healing
PBMT Influence on Alveolar Socket Preservation
Goal of this study is to compare between the effect of two different low power lasers on extraction socket healing.
- Trial name
- NCT05911607
- Testing
- Low power laser
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Photodynamic Therapy, Third Molar Extraction
The Effect of Photodynamic Therapy on Post-extraction Third Molar
The extraction of lower third molars is one of the most frequent procedures in oral surgery. For this reason, the extraction of these teeth generally requires a surgical approach involving the elevation of a mucoperiosteal flap…
- Conditions
- Photodynamic Therapy, Third Molar Extraction, Antimicrobial Photodynamic Therapy
- Trial name
- NCT06964178
- Testing
- Experimental: antimicrobial photodynamic therapy (aPDT) after extraction of third molar
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Post-Extraction Socket Hemostasis, Post-Extraction Socket Pain Relief
Comparison of A-PRF vs Bone Wax in Hemostasis, Pain Relief and Healing Following Exodontia
The goal of this clinical trial is to compare the pain relief and healing effect of A-PRF and Bone-wax in patients having mandibular tooth-extractions.
- Conditions
- Post-Extraction Socket Hemostasis, Post-Extraction Socket Pain Relief, Post-Extraction Socket Healing
- Trial name
- NCT05744726
- Testing
- A-PRF, Bone-wax
- Where
- Pakistan
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Healing Wound, Alveolar; Wound
Ultrasound for Socket Healing Evaluation
The design is a single blinded, dual comparative study of ultrasound versus micro-CT/LASCA in one study group. Up to a total of 140 subjects registered will be recruited.
- Conditions
- Healing Wound, Alveolar; Wound, Alveolar Bone Loss, Image
- Trial name
- NCT06017193
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Extraction Socket Healing, Extraction, Tooth
The Effect of Collagen In Tooth Extraction Procedures
This study is aimed at assessing the effect of an animal-derived collagen matrix on bone and soft tissues in the human teeth. Single-rooted teeth that are beyond restoration and in need of extraction will be included in the…
- Trial name
- NCT07270510
- Testing
- Collagen Matrix soft tissue graft
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Bone Regeneration, Bone And Bones
Effects of Autogenous Dentin Graft on Socket Preservation
Various graft materials are used to reconstruct bone defects in the jaws due to tooth loss, trauma, advanced periodontal diseases, pathological lesions and congenital disorders.
- Conditions
- Bone Regeneration, Bone And Bones, Bone Substitutes
- Trial name
- NCT04131894
- Testing
- autogenous dentin graft, platelet rich fibrin (PRF)
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Tooth Extraction Site Healing, Alveolar Ridge Preservation
Assessment of the Impact of Neobone® (Biphasic Calcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
The goal of this randomized clinical trial is to assess whether BCP (Biphasic Calcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction.
- Trial name
- BCPARPBV (NCT07638358)
- Testing
- Neobone® (Biphasic Calcium Phosphate)
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Tooth Extraction
The Clinical and Biological Effects of Leucocyte and Platelet-rich Fibrin (L-PRF) on Post-extraction Sockets Healing
This study evaluates the clinical and biological effects of leucocyte and platelet-rich fibrin (L-PRF) on post-extraction sockets healing.
- Trial name
- NCT03985033
- Testing
- leucocyte and platelet-rich fibrin (L-PRF)
- Where
- Hong Kong
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The European Research Group on Periodontology (ERGOPerio)
Alveolar Bone Resorption, Wound Heal
Alveolar Socket Healing With and Without PRGF
A single-centre randomised controlled pilot study involving 12-24 healthy adult patients for investigating dental extraction socket healing with and without plasma rich in growth factors (PRGF) taking place during early days of…
- Trial name
- NCT04383158
- Testing
- PRGF ENDORET® obtained from ENDORET® POST-EXTRACTION ALVEOLUS DENTAL KIT (KMU16)
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Healing Wound
Healing Effect of Ziziphus Honey on Extracted Tooth Socket in Humans by Evaluating the Levels of BMP-2 and OPN
Ziziphus honey can improve bone healing at extracted tooth sockets in humans by increasing salivary levels of bone markers, OPN and BMP-2.
- Trial name
- NCT05025306
- Testing
- ziziphus honey
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Medical Institute, Lahore
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluating The Use of CGF Made Plugs in Mandibular Extraction Sites of Lower Impacted 3rd Molars.
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) plugs help improve bone healing and reduce pain after the surgical removal of impacted lower third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07484997)
- Testing
- Concentrated Growth Factor (CGF) Plug
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mesh, Healthy Volunteer
Improving Healing in Children After Tooth Extraction Using Laser Therapy or Hyaluronic Acid
Tooth extraction may be an unpleasant and painful experience for children, Post-extraction wound healing. Low-level laser therapy (LLLT) is a widely used adjuvant treatment for wound healing, resulting in both an increase in cell…
- Conditions
- Mesh, Healthy Volunteer, Low Level Laser Therapy, Hyaluronic Acid Gel for Preservation the Extraction Socket
- Trial name
- LLLT vs HA (NCT07205640)
- Testing
- Low-Level Laser Therapy, Hyaluronic Acid (HA)
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Wound Heal
The Efficacy of Hyaluronic Acid and Honey in Healing of Multiple Extraction Sockets of Primary Teeth Compared to Saline
This study aims to evaluate the effect of hyaluronic acid and honey compared to saline in healing of multiple extraction sockets of primary teeth in a group of children aging from Two to Seven years old.
- Trial name
- NCT05161403
- Testing
- Hyaluronic acid, honey
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis, Dental Caries
Comparison of Topical Analgesic With Saline Rinses in Post Extraction Healing
The aim of this study is to determine the beneficial effect of mouth rinses, both topical analgesic and saline regimens as an adjuvant therapy in the presence of standard prescription of post-operative pain killers on the…
- Conditions
- Periodontitis, Dental Caries, Hypertension
- Trial name
- NCT02921165
- Testing
- analgesic mouth rinses (dissolved Aspirin), Normal saline rinses.
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Aga Khan University