Clinical trials: Health, open to volunteers
Depression
Activity and Recreation in Communities for Health
This project tests whether a health outreach intervention that promotes engagement in rewarding, community-based recreational and social activities can produce greater improvements in depressive symptoms, adiposity, and physical…
- Trial name
- ARCH (NCT06093282)
- Testing
- ARCH, Traditional Health Outreach
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Rush University Medical Center
Multiple Chronic Conditions, Patient Engagement
AI-Augmented Motivational Interviewing Training for Primary Care
This study will examine the impact of training primary care providers (PCPs) in motivational interviewing (MI) using artificial intelligence (AI) to augment the training process.
- Conditions
- Multiple Chronic Conditions, Patient Engagement, Burnout, Professional, Motivational Interviewing
- Trial name
- AIM-PC (NCT06597123)
- Testing
- Basic AI (artificial intelligence)-Augmented Motivational Interviewing Training, Plus AI (artificial intelligence)-Augmented Motivational Interviewing Training
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Wright State University
Smoking Cessation
Stop Smoking in Spine Surgery
Patients that are subjected to a medium complex surgical intervention in neck (posterior) or lumbar spine (posterior) with instrumentation are motivated to stop smoking.
- Trial name
- NCT06361459
- Testing
- Stop smoking
- Where
- Netherlands
- Volunteers
- 210 people
- Sponsor
- Leiden University Medical Center
Health Misinformation, Misinformation
Cognitive and Emotional Inoculation Against Nutrition-Related Misinformation in Young Adults
This study aims to examine the effects of cognitive and emotional inoculation interventions on young adults' ability to identify and respond to nutrition-related misinformation on social media.
- Conditions
- Health Misinformation, Misinformation, Digital Health Literacy, Health Communication
- Trial name
- NCT07803380
- Testing
- Cognitive Game-Based Inoculation., Emotional Game-Based Inoculation., General Nutrition Health Education.
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Beijing Normal University
Asthma (Diagnosis)
Changing Lifestyle to Improve Quality of Life in Spanish Adolescents With Asthma
The goal of this clinical trial is to evaluate if a multicomponent lifestyle intervention can improve health-related quality of life in adolescents with asthma.
- Trial name
- CLiQ-Asthma (NCT07870980)
- Testing
- Lifestyle-change intervention
- Volunteers
- 96 people
- Sponsor
- Universitat Internacional de Catalunya
Public Health, Public Health System Research
Early ECG Prediction of Multi-system Disease Cohort Establishment and Follow Up
This registered multicenter study aims to investigate the diagnostic efficacy of artificial intelligence-enhanced electrocardiography (AI-ECG) in detecting multi-system diseases.
- Conditions
- Public Health, Public Health System Research, Multi-system Disease Diagnosis
- Trial name
- EARLY-ECG-PRED (NCT06924580)
- Testing
- ECG screening
- Where
- China
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Osteoporosis in Post-menopausal Women
Bone Health in Postmenopausal Women: The Effect of Exercise With or Without Medication for Osteoporosis
Osteoporosis is a systemic bone disorder characterised by a reduced bone mass and structural deterioration, increasing the risk of fragility fractures, particularly in women post-menopause.
- Trial name
- BEAT-OP (NCT07267325)
- Testing
- EXERCISE TRAINING, Antiresorptive medication (routine clinical care)
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Healthcare Professionals
The Impact of Mindfulness-Based Stress Reduction on Mindfulness, Self-Compassion, and Perceived Stress Among Healthcare Professionals
Mindfulness is defined as a state of awareness in which an individual consciously pays attention to the present moment without judgment, reaction, or resistance, thereby promoting mental and psychological well-being.
- Trial name
- NCT07022613
- Testing
- Mindfulness-Based Stress Reduction Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Back Pain, Neck Pain
Workplace Exercise Therapy With or Without Manual Therapy in Chronic Spinal Pain
Implementing workplace strategies to manage symptoms in office workers with chronic nonspecific spinal pain (CNSP) may improve both health- and work-related outcomes, as adherence to these interventions is more feasible in this…
- Conditions
- Back Pain, Neck Pain, Low Back Pain
- Trial name
- NCT07251959
- Testing
- Exercise therapy, Manual Therapy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Catholic University of Murcia
Medication Adherence
Investigation of a Patient Support Intervention for Statin Medication Adherence
Statins have been demonstrated to significantly reduce the risk of cardiovascular disease, but adherence to these medications is suboptimal.
- Trial name
- NCT06972979
- Testing
- Text Message Gamification and Remote Support
- Where
- United States
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Cardiometabolic Risk Factors
Dissecting the Roles of High-quality Diets and Ultra Processed Foods on Cardiometabolic Health
Controversy remains around the role of ultra-processed food (UPF) consumption and health outcomes. A key question that remains to be answered is: when diet quality is the same, does food processing itself have any independent…
- Trial name
- NCT06749327
- Testing
- High UPF, high hPDI diet, Low UPF, high hPDI diet
- Where
- 2 sites in Ireland, United Kingdom
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Child Development
Shanghai Children's Health, Education and Lifestyle Evaluation, Preschool (the SCHEDULE-P Study)
Shanghai is one of pilot areas for the early education of 3-6 years old infants in China. Shanghai Municipal Education Commission has been actively exploring more effective early education guidance methods.
- Trial name
- NCT04037761
- Where
- China
- Volunteers
- 20,899 people
- Sponsor
- Sijia Gu
Lupus Erythematosus
Identification of Modifiable Sleep-related Factors in Patients With Systemic Lupus Erythematosus.
Background: Sleep quality is a key determinant of physical and mental health, with important implications for immune regulation, psychological well-being, and overall quality of life.
- Trial name
- NCT07483541
- Testing
- Adults with systemic lupus erythematosus
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Smoking Cessation, Mobile Health
Metaphor-Based Smoking Cessation Intervention
This study aims to evaluate the effectiveness and participant experiences of a WeChat-delivered, metaphor-based smoking cessation intervention.
- Trial name
- NCT07803354
- Testing
- Metaphor-based smoking cessation intervention, 5A's/5R's advice, Health warning leaflet
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Normal University
Physical Activity Attitude, Health Behavior
Trust in Institutions, Environment, and Physical Activity
Trust is the willingness of people to cooperate. Although much research has been conducted on physical activity, little research has explored trust in institutions regarding environmental and physical activity recommendations.
- Conditions
- Physical Activity Attitude, Health Behavior, Trust
- Trial name
- TrustAndMove (NCT07472569)
- Where
- France
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Heart Defects, Congenital, Mental Health Issue
Mind the Heart - Mental Health in Children and Adolescents With Congenital Heart Defects
The aim of the Mind the Heart study is to document the feasibility of an online parent/child administered screening model for mental disorders (MDs) in Danish children and adolescents with congenital heart disease (CHD).
- Trial name
- Mind the Heart (NCT05709470)
- Testing
- No-intervention
- Where
- Denmark
- Volunteers
- 4,800 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Mental Health Issue, Depression
Just-in-Time Training for Youth Mentors
This study will evaluate the usability, feasibility, and acceptability of a novel multi-level Just-In-Time Training (JITT) implementation strategy (JITT-EBP) that aims to equip mentors and mentor supervisors to implement…
- Conditions
- Mental Health Issue, Depression, Anxiety
- Trial name
- NCT07129070
- Testing
- Interpersonal Psychotherapy-Adolescent Skills Training via Just-In-Time Training (JITT) implementation strategy, Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST) implemented via usual training
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking Cessation
Tobacco Education and Lung Health Study (TEAL)
Primary Objective To compare two smoking cessation interventions among individuals undergoing lung cancer screening. Primary outcomes are: 3-month self-reported abstinence from cigarettes and 6-month self-reported and bioverified…
- Trial name
- TEAL (NCT06290869)
- Testing
- Phone-based Tobacco Treatment, Nicotine Replacement, and Stepped Care Intervention, E-Referral to the Tobacco Quitline
- Where
- United States
- Volunteers
- 1,188 people
- Sponsor
- Georgetown University
Obstructive Sleep Apnea, Sleep Disorder
Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Before and After Ventilotherapy
This observational study aims to evaluate multiple dimensions of health in patients with Obstructive Sleep Apnea Syndrome (OSAS), before and after three weeks of ventilotherapy.
- Conditions
- Obstructive Sleep Apnea, Sleep Disorder, Well-Being, Psychological, Cognitive Impairment
- Trial name
- MULTI-OSAS (NCT06312956)
- Testing
- Continuous Positive Airway Pressure Ventilotherapy
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Istituto Auxologico Italiano
Exercise Therapy, Behavior and Behavior Mechanisms
Health-Enhancing Adapted Physical Activity Program at "Mon Stade"
Introduction: Regular practice of exercise or physical activity (PA) is a recognized intervention as a determinant of good health acquisition, maintenance, or recovery for a large number of chronic pathologies.
- Conditions
- Exercise Therapy, Behavior and Behavior Mechanisms, Adherence, Patient, Lifestyle, Sedentary
- Trial name
- SESAME (NCT04716322)
- Testing
- Adapted Physical Activity
- Where
- France
- Volunteers
- 2,024 people, healthy volunteers welcome
- Sponsor
- Mon Stade Sports Medicine Centre
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