Clinical trials: Health Care
Heart Failure, Pulmonary Disease, Chronic Obstructive
Advancing Symptom Alleviation With Palliative Treatment
Chronic heart failure (CHF), chronic obstructive pulmonary disease (COPD), and interstitial lung disease (i.e., pulmonary fibrosis) are common serious illnesses.
- Conditions
- Heart Failure, Pulmonary Disease, Chronic Obstructive, Emphysema, Pulmonary Fibrosis, Interstitial Lung Disease
- Trial name
- ADAPT (NCT02713347)
- Testing
- ADAPT Intervention
- Where
- 2 sites in United States
- Volunteers
- 306 people
- Sponsor
- VA Office of Research and Development
PTSD, Depression
Online and Shared Decision-Making Interventions to Engage Service Men and Women in Post-Deployment Mental Health Care
OEF/OIF/OND war Veterans have unique post-deployment care needs that the VA is striving to understand and address. Unfortunately, there is a significant disparity in utilization of mental health (MH) care and VA access as most…
- Conditions
- PTSD, Depression, Substance Use Disorder, Traumatic Brain Injury
- Trial name
- eSDM (NCT03539068)
- Testing
- WEB-ED+ Treatment Arm
- Where
- United States
- Volunteers
- 1,312 people
- Sponsor
- VA Office of Research and Development
Chronic Disease
Preparing Spanish-speaking Older Adults for Advance Care Planning and Medical Decision Making (PREPARE)
In partnership with patients, caregivers, advocacy groups and clinicians, the investigators plan to: Aim 1: Adapt and refine PREPARE in Spanish through cognitive interviews with Spanish-speaking Latinos and stakeholders.
- Trial name
- NCT02072941
- Testing
- PREPARE Intervention
- Where
- United States
- Volunteers
- 445 people
- Sponsor
- University of California, San Francisco
Obesity
A Study to Assess the Compliance and Impact on Weight of Kurbo, a Pediatric Centered Weight Loss App
Kurbo is a health and fitness app that is targeted toward the pediatric population. It utilizes games and activities to educate children about healthy eating, portion control/size and exercise.
- Trial name
- Kurbo (NCT02880254)
- Testing
- Kurbo, Personal Health Coach
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
Obesity, Overweight
Balance: A Pragmatic Trial of a Digital Health Intervention to Prevent Weight Gain in Primary Care
Up to 50% of obese patients are not interested in, or ready for, weight loss. Clinical practice guidelines clearly recommend that these patients avoid gaining weight.
- Conditions
- Obesity, Overweight, Overnutrition, Nutrition Disorders
- Trial name
- D0479 (NCT03003403)
- Testing
- Intervention Program
- Where
- United States
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- Duke University
Health Care Provider Education
Complementary Therapies in Palliative Care
Palliative care represents one of the most rapidly expanding sectors of health care. Its rapid growth has been accompanied by widespread needs for training of multidisciplinary personnel to work with the unique set of health…
- Trial name
- CTPC (NCT02644356)
- Testing
- Online CE/CME course
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Collinge and Associates, Inc.
COVID-19
Drug Use Investigation of COMIRNATY Intramuscular Injection
Post-marketing study, Chotor study of COMIRNATY vaccenees followed for 11months. Serious adverse events and COVID-19 observed during the follow-up period will be collected, and the long-term safety of this product will be…
- Trial name
- NCT04815031
- Testing
- BNT162b2
- Where
- Japan
- Volunteers
- 14,570 people, healthy volunteers welcome
- Sponsor
- Pfizer
Medication Adherence
ARemind: A Personalized System to Remind for Adherence
The main aim of this phase II proposal is to continue and complete development of a cellular phone-based system that assists patients with their medication adherence.
- Trial name
- ARemind (NCT01229722)
- Testing
- Beeper, ARemind
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Dimagi Inc.
Dementia, Mental Health
Compass for Care: A Theory-driven Mobile Solution to Promote Well-being Among Caregivers of Individuals With ADRD
In the US, the over 11 million Americans currently providing unpaid care to a family member, relative, or friend with Alzheimer's disease or a related dementia (ADRD) are over 6 times more likely than the general population to…
- Trial name
- Compass4Care (NCT06249139)
- Testing
- Compass for Care (Well-being intervention), Compass for Care (Safety intervention)
- Where
- United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Pro-Change Behavior Systems
Depression, Anxiety
A Transdiagnostic Course for Common Mental Health Problems in Primary Care
This study investigates the feasibility of a transdiagnostic course that is intended to work for a large variety of patient groups with clinically significant depression or anxiety in primary care.
- Trial name
- NCT04522713
- Testing
- Behavioral activation, evidence-based sleep strategies including sleep restriction, exposure-based strategies, promotion of physical activity and recuperating activities, psychoeducational material
- Where
- 2 sites in Sweden
- Volunteers
- 91 people
- Sponsor
- Karolinska Institutet
Smoking Cessation, Cancer
Tobacco Treatment Comparison for Cancer Care
This pilot comparative effectiveness trial will compare two active smoking cessation treatments in terms of effectiveness, equity across patient subpopulations, and efficiency among adult patients diagnosed with cancer within the…
- Trial name
- NCT06218823
- Testing
- Transdermal Nicotine Patch, Standard Telephone Counseling, Varenicline
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Wisconsin, Madison
Diabetes Mellitus, Type 2
Impact of Pharmacy Clinic on Diabetes Management
The Beaumont Hospital Royal Oak Outpatient Clinic (and other listed Beaumont recruiting locations) care for over 900 patients with diabetes.
- Trial name
- PharmaMD (NCT03377127)
- Testing
- Pharmacy Managed Diabetes Clinic (PMDC), Standard of Care (SOC)
- Where
- 4 sites in United States
- Volunteers
- 86 people
- Sponsor
- Corewell Health East
COVID-19, Vaccine Refusal
CATCH-UP Vaccines: Engaged Approaches to Testing in Community/Healthcare Settings for the Underserved (COVID-19)
Oklahoma has high COVID-19 incidence, particularly among underserved minority and rural Oklahomans. Oklahoman's are also reporting SARS-CoV-2 vaccine hesitancy and signs of slowing vaccine uptake, with increased hesitancy among…
- Trial name
- NCT05236270
- Testing
- Text Message, Motivational Interviewing, Electronic Educational Message with Tailored Questions/Prompts
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Obesity, Overweight
The Peer Assisted Lifestyle Intervention
The PAL intervention uses a new software tool delivered on tablets to facilitate 5As-based weight management counseling with a peer health coach and the VA PACT healthcare team to promote goal-setting, behavior change, and weight…
- Trial name
- PAL (NCT03163264)
- Testing
- Peer Assisted Lifestyle, Enhanced Usual Care
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- VA Office of Research and Development
Acne Vulgaris
To Compare the Efficacy and Safety of Clindamycin Phosphate 1.2% / Benzoyl Peroxide 5% Gel of CHL Versus DUAC® Gel
This is an Randomized, Double-blind, Multicentric, Parallel-group, Active and Placebo Controlled, Three Arm Clinical Study. The main objective is to evaluate bioequivalence of Test formulation (Clindamycin Phosphate 1.2%/Benzoyl…
- Trial name
- NCT02005666
- Testing
- Clindamycin Phosphate 1.2% / Benzoyl Peroxide 5% Gel, DUAC® Gel
- Where
- 36 sites in United States, India
- Volunteers
- 850 people
- Sponsor
- Zydus Lifesciences Limited
Adherence
A Universal Medication Schedule to Promote Adherence to Complex Drug Regimens
This study will leverage available technologies and test strategies to impart the Universal Medication Schedule (UMS) in primary care to help patients understand, consolidate, safely use, and adhere to their complex medication…
- Trial name
- NCT02820753
- Testing
- EHR + (Text or Portal)
- Where
- United States
- Volunteers
- 677 people
- Sponsor
- Northwestern University
HIV Infections, Drug Use
INTEGRA: A Vanguard Study of Health Service Delivery in a Mobile Health Delivery Unit
The purpose of this study is to determine the efficacy of using a mobile health delivery unit ("mobile unit") to deliver "one stop" integrated health services - particularly medication for opioid use disorder (MOUD) and…
- Conditions
- HIV Infections, Drug Use, Opioid Use, Opioid-use Disorder
- Trial name
- INTEGRA (NCT04804072)
- Testing
- Medication for opioid-use disorder (MOUD) for opioid-use disorder (OUD), HIV testing, HIV treatment for participants living with HIV not already in care
- Where
- 5 sites in United States
- Volunteers
- 447 people
- Sponsor
- HIV Prevention Trials Network
Medication Adherence
Development and Evaluation of an Electronic Health Record-based Medication Complete Communication (EMC2) Strategy
There is a well-documented need for effective interventions that can help patients understand and safely adhere to prescribed medications, particularly those with greater potential for harm if not taken correctly.
- Trial name
- NCT03652272
- Testing
- EMC2
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Northwestern University
SARS-CoV-2
Rapid SARS-CoV-2 IgG Antibody Testing in High Risk Healthcare Workers
The purpose of this study is to validate the use of a rapid, at home, point-of-care (POC) SARS-CoV-2 IgG antibody test in high risk healthcare workers.
- Trial name
- COVID-Antibody (NCT04334876)
- Testing
- SARS-CoV-2 IgG Antibody Testing Kit
- Where
- United States
- Volunteers
- 571 people
- Sponsor
- Indiana University
Post Traumatic Stress Disorder
Using Mobile Technology to Address the Trauma Mental Health Treatment Gap
BounceBack Now (BBN) is a self-help, trauma-focused mental health mobile application (app) with automated assessment with treatment guidance and in-app evidence-based treatment support for depression, post-traumatic stress…
- Trial name
- NCT05374408
- Testing
- Aim 2: BounceBack Now (BBN) for Trauma Informed Care Deployment, Aim 1 Participant Focus Groups, Aim 1 BHP Focus Groups
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
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