Clinical trials: Health Data
Maternal Health, Infant Health
Using Advanced Data Systems to Improve Health in Early Life in Rural Nepal
The goal of this cluster randomized controlled trial is to study the effect of a mobile-phone based application used by pregnant women on maternal and newborn health indicators.
- Conditions
- Maternal Health, Infant Health, Institutional Delivery, Birth Preparedness and Complication Readiness
- Trial name
- CITH (NCT05697822)
- Testing
- Mobile Phone and Cloud-based Electronic Contact and Recording System
- Where
- Nepal
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Amit Arjyal
Opioid-use Disorder, Overdose of Opiate
Patient Reported Outcomes for Opioid Use Disorder
The goal of the project is to build a clinical data research infrastructure that will begin to enhance capacity to use electronic health record (EHR) data and patient reported outcomes measures (PROs) to conduct opioid related…
- Conditions
- Opioid-use Disorder, Overdose of Opiate, Patient Participation
- Trial name
- NCT03985163
- Testing
- Patient Reported Outcomes Electronic Survey
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Yale University
Attitude to Computers, Attitude of Health Personnel
An Interactive Patient-Centered Consent for Research Using Medical Records
The goal of this project is to develop and evaluate a novel, electronic informed consent application for research involving electronic health record (EHR) data.
- Conditions
- Attitude to Computers, Attitude of Health Personnel, Researcher-Subject Relations, Trust
- Trial name
- NCT03063268
- Testing
- Trust-Enhanced Messaging on E-Consent, Interactive features on E-Consent, Standard E-Consent
- Where
- United States
- Volunteers
- 734 people, healthy volunteers welcome
- Sponsor
- University of Florida
Aneuploidy, Genetic Disease
Effect of Video Education on Patients' Knowledge and Attitudes of Privacy in Prenatal Genetics
The investigators propose a randomized controlled trial to assess baseline maternal knowledge of and attitudes toward commercial prenatal genetic testing laboratories' genetic privacy practices, and to determine whether a brief…
- Conditions
- Aneuploidy, Genetic Disease, Pregnancy Related
- Trial name
- NCT04420858
- Testing
- Enhanced (experimental) education, Standard (control) education.
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Diabetes Mellitus
ASCEND: ApproacheS to CHC ImplEmeNtation of SDH Data Collection and Action
This work will test a set of strategies for helping community health centers (CHCs) routinely identify and take action on the SDH-related needs of patients with / at risk for DM using a stakeholder-driven process to develop…
- Trial name
- ASCEND (NCT03607617)
- Testing
- SDH Tool
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Dementia, Alzheimer Disease
The Brain Health Study: A Pragmatic, Patient-Centered Trial
The eRADAR Brain Health Study is an embedded, pragmatic clinical trial to determine whether targeted screening for dementia using the eRADAR algorithm increases dementia detection within primary care compared to usual care.
- Trial name
- eRADAR (NCT05905796)
- Testing
- Brain Health Assessment
- Where
- 3 sites in United States
- Volunteers
- 1,261 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Severe Mental Disorder, Schizophrenia
Development of a Model for Digital Monitoring of the Mental State of the Hospitalized Patient
This study presents the development and validation of a unique Digital Experience Sampling Method (ESM) questionnaire specifically adapted for monitoring changes in the mental state of patients during psychiatric hospitalization.
- Conditions
- Severe Mental Disorder, Schizophrenia, Personality Disorders, Mood Disorders
- Trial name
- NCT06182787
- Where
- Israel
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Prostate Cancer
Improving Engagement From Underserved Communities With Prostate Cancer Genetics Services
Earlier work explored barriers and facilitators to accessing prostate cancer screening, particularly in underserved communities, and provided valuable insights to build upon.
- Trial name
- INCLUDE PC (NCT07407686)
- Testing
- Surveys, Semi-structured interviews and focus groups
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Artificial Intelligence Mobile Application
Food-i-Sense Analytics: Integrating AI Into Continuous Glucose Monitoring Data Analysis for Precision Nutrition.
This study aims to improve how we understand and manage blood sugar responses in adults without diabetes. Even in people who appear healthy, blood sugar levels after meals can behave in different ways.
- Trial name
- Food_i Sense (NCT07626658)
- Testing
- Continuous glucose monitoring using a wearable sensor (flash interstitial glucose monitor)
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- IMDEA Food
Depression, Suicidality
Saving and Empowering Young Lives in Europe (Israel)
SEYLE is a health promoting program for adolescents in European schools. Its main objectives are to lead adolescents to better health through decreased risk-taking and suicidal behaviors, to evaluate outcomes of different…
- Trial name
- SEYLE-ISRAEL (NCT00906620)
- Testing
- QPR: question, persuade and refer (SEYLE)
- Where
- Israel
- Volunteers
- 1,247 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Pregnancy-Related and Neonatal Disorders
Early Diagnosis and Prediction of Maternal and Neonatal Diseases:
This is a multi-center, clinical study designed to evaluate the application and effectiveness of an AI-assisted predictive model for identifying maternal and neonatal diseases, leveraging multimodal health data.
- Trial name
- EDPMND (NCT06791343)
- Testing
- AI-Based Diagnostic and Prognostic Model
- Where
- 3 sites in China
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- The Eye Hospital of Wenzhou Medical University
Healthy
ActivE³ - Everyone, Everywhere, Everyday WP 2 - Personalized Data-driven Coaching Platform for Stimulating and Promoting Active Lifestyle and Health Risk Prevention
The objective of WP2 of the Active3 project is to develop a digital solution for promoting and monitoring physical activity in social settings (real or virtual) that implements a Preventive Medicine approach to healthy aging.
- Trial name
- Active3-WP2 (NCT07350915)
- Testing
- Digital Therapeutics
- Where
- Italy
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Politecnico di Milano
Bipolar Disorder (BD), Bipolar Disorder I or II
FOCUS Bipolar: Families Opening Conversations for Understanding Signs
Bipolar disorder often runs in families, but early symptoms in youth can go unrecognized for years. This project evaluates a structured, family-centered approach to informed screening for youth ages 7-21 who have a biological…
- Conditions
- Bipolar Disorder (BD), Bipolar Disorder I or II, Bipolar Disorder Family Members, Screening Tool
- Trial name
- FOCUS Bipolar (NCT07622927)
- Testing
- Co-design Workshop (Observational Procedure), Alpha Testing (Observational Procedure), Beta Testing (Observational Procedure)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
HIV, Tuberculosis
Evaluation of South Africa's National Adherence Strategy
NOTE THAT THE STUDY IS LED BY SOUTH AFRICA NATIONAL DEPARTMENT OF HEALTH AND WORLD BANK WITH SUPPORT FROM BOSTON UNIVERSITY. The South Africa National Department of Health (NDOH) intends to launch its newly developed National…
- Conditions
- HIV, Tuberculosis, Diabetes, Hypertension
- Trial name
- ENHANCE (NCT02536768)
- Testing
- Minimum package of interventions to improve ART adherence
- Where
- South Africa
- Volunteers
- 8,020 people, healthy volunteers welcome
- Sponsor
- Boston University
Pre-Exposure Prophylaxis
Leveraging Electronic Health Record Data in a Risk Prediction Model to Increase HIV PrEP Intake in Primary Care
Kaiser Permanente Northern California (KPNC) has been a national leader in implementation of HIV preexposure prophylaxis (PrEP), a daily antiretroviral pill that is more than 99% effective in preventing HIV acquisition.
- Trial name
- NCT05991869
- Testing
- Point-of-care decision support intervention
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Education, Health
Disentangling the Role of Culture, Life Stage, and Information Design to Facilitate Equity in Data Report Back
There remains a need for novel research that facilitates RBRR in a manner that raises data and environmental health literacy (D/EHL) and supports communities striving for environmental health and structural change.
- Trial name
- NCT06729775
- Testing
- Data report back preference by life span
- Where
- United States
- Volunteers
- 1,546 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Stroke, Health Behavior
A Study for the Collection of Clinical Data for Stroke Patients and Healthy Subjects
This study aimes to medical data, musculoskeletal data and functional data over time of stroke patients and healthy subjects to compared the clinical differences between stroke and healthy subjects.
- Trial name
- NCT05908994
- Testing
- Examination
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bundang CHA Hospital
Sleep, Alertness, Fatigue, Mood, and Performance
Circadian-informed Optimal Bedtime
The goal of this interventional study is to test whether circadian-informed bedtime recommendations can improve sleep, next-day psychomotor vigilance, and subjective well-being among healthy adults.
- Conditions
- Sleep, Alertness, Fatigue, Mood, and Performance, Well-being
- Trial name
- LS4 (NCT07889466)
- Testing
- Optimal Bedtime
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Dementia, Alzheimer Disease
The Brain Health Study: A Pragmatic, Patient-Centered Trial
The eRADAR Brain Health Study seeks to refine and test a novel, low-cost strategy for increasing dementia detection within primary care.
- Trial name
- NCT05356702
- Testing
- Brain Health Assessment
- Where
- 5 sites in United States
- Volunteers
- 3,417 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Electrocardiography (ECG), Photoplethysmography
Synchronised ECG and PPG Data Collection for AI-based QT/QTc Reconstruction (ILECS-ECGPPG)
This observational study will collect synchronized photoplethysmography (PPG) and electrocardiogram (ECG) recordings from approximately 50 healthy adult volunteers.
- Conditions
- Electrocardiography (ECG), Photoplethysmography, Healthy Volunteers
- Trial name
- ILECS-ECGPPG (NCT07684807)
- Testing
- Corsano CardioWatch 287-2, VivaLNK wearable ECG patch
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Corsano Health B.V.