Clinical trials: Health Economics
HELICOBACTER PYLORI INFECTIONS
Fecal Molecular Susceptibility-guided Hp First-line Therapy
The goal of this clinical trial is to evaluate the eradication efficacy and health economic benefits of individualized regimens guided by fecal molecular susceptibility testing with 7-day and 14-day courses in the first-line…
- Trial name
- NCT07405684
- Testing
- 7-day fecal molecular susceptibility-guided therapy, 14-day fecal molecular susceptibility-guided therapy
- Where
- 4 sites in China
- Volunteers
- 544 people
- Sponsor
- Shanghai Zhongshan Hospital
Head and Neck Squamous Cell Carcinoma
Protocole Advanced RadioTherapy ORL
The purpose of this study is to do health economic evaluation of tomotherapy and dynamic arctherapy (2 techniques exist: RapidArc and Vmat).
- Trial name
- ART-ORL (NCT02024035)
- Testing
- Radiotherapy
- Where
- 14 sites in France
- Volunteers
- 180 people
- Sponsor
- Centre Leon Berard
Stroke
Rural CT Examination and Thrombolytic Treatment for Stroke
To counteract long term sequelae from stroke, ultrarapid diagnosis and treatment, high quality multidiciplinary in-hospital care and optimal long term rehabilitation is required.
- Trial name
- RURALCT (NCT03577847)
- Testing
- Rural CT scanning
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Vestre Viken Hospital Trust
Acute Pulmonary Embolism
HOME-PE2 : Home Treatment Versus Hospitalization in Patients With Acute Pulmonary Embolism, no Clinical Severity Criteria, and Either Right Ventricular Dysfunction or Elevated Troponin: a Randomized Controlled Trial
This study (HOME-PE2) is a multicenter, randomized controlled trial comparing home treatment versus hospitalization in patients with acute pulmonary embolism (PE) who have no clinical severity criteria according to the Hestia…
- Trial name
- HOME-PE2 (NCT07506291)
- Testing
- Home treatment, Hospitalization
- Where
- 18 sites in France
- Volunteers
- 568 people
- Sponsor
- University Hospital, Angers
Genital Warts, Human Papilloma Virus
Typing of Human Papilloma Virus (HPV) From Female Genital Warts
This is a longitudinal observational study of women presenting to Groote Schuur Hospital with genital warts. The study will evaluate the socio-demographic characteristics of the women using a structured questionnaire.
- Trial name
- NCT01192282
- Testing
- Medical / Surgical Treatment
- Where
- South Africa
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Hypertension, Medication Adherence
Behavioral Economics to Improve Antihypertensive Therapy Adherence
Hypertension represents a major cardiovascular risk factor that can be controlled through the use of medications, yet medication non-adherence represents a common problem that leaves patients at elevated risk for adverse…
- Trial name
- BETA (NCT04029883)
- Testing
- Text Message, Behavior Economic Incentive
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cedars-Sinai Medical Center
Diabetes Mellitus, Hypertension
The Long-term Spill-over Impact of COVID-19 on Health and Healthcare of People With Non-communicable Diseases
Objectives and aim: To evaluate the long-term spill-over (indirect) effect of Coronavirus disease (COVID-19) on health outcomes and healthcare utilization among people with non-communicable diseases and without COVID-19.
- Conditions
- Diabetes Mellitus, Hypertension, Cancer, Cardiovascular Diseases
- Trial name
- NCT05248412
- Testing
- COVID-19 outbreaks
- Where
- China
- Volunteers
- 250,000 people
- Sponsor
- The University of Hong Kong
Myocardial Infarction, Acute, Myocardial Infarction
A Behavioral Economics-Based Telehealth Intervention to Improve Post-MI Medication Adherence
The proposed study is a pilot randomized clinical trial (RCT). Participants in the intervention arm will participate in a 90-day adherence promotion program based on the theory of behavioral economics and administered through the…
- Trial name
- NCT03022266
- Testing
- Financial Incentive and Mobile Phone App
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Wellth Inc.
Depressive Symptoms, Substance Use
Evaluation of an Entrepreneurship Program for American-Indian Youth
This study will use a randomized controlled design to evaluate whether a youth entrepreneurship/life-skills intervention for reservation-based American Indian adolescents (ages 13-15) improves psychosocial, behavioral health…
- Trial name
- NCT02157493
- Testing
- Arrowhead Business Group Curriculum, Recreational League Control Condition
- Where
- United States
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Traumatic Brain Injury
The Impact of Traumatic Brain Injury in the Elderly
A better understanding of the impact of Traumatic Brain Injury (TBI) in the elderly, in terms of brain damage, cognitive and motor functions, sleep quality and quality of life is necessary due to the increasing incidence and…
- Trial name
- NCT04070092
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Aging, Benzodiazepine Sedative Adverse Reaction
NUDGE-EHR Replication Trial at Mass General Brigham
Prescribing of potentially unsafe medications for older adults is extremely common; benzodiazepines and sedative hypnotics are, for example, key drug classes frequently implicated in adverse health consequences for vulnerable…
- Conditions
- Aging, Benzodiazepine Sedative Adverse Reaction, Anticholinergic Adverse Reaction, Adverse Drug Event
- Trial name
- NUDGE-EHR (NCT05538065)
- Testing
- Follow-up booster Alert, Pre-commitment, Enhanced Alert
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Brigham and Women's Hospital
Short Interpregnancy Intervals, Maternal Health Disparities
Planning Together: A Couple-based, Multi-level Prenatal Contraceptive Education Program for Economically Marginalized Families
The goal of this pilot trial is to examine the feasibility and acceptability of the Planning Together protocol The hypothesis of this study are 1.
- Trial name
- NCT07214012
- Testing
- Joint contraceptive and couple communication education, Couple communication consultation with Interventionist to increase partner engagement and improve communication, Check-ins to support continued partner support & communication
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Tennessee Graduate School of Medicine
Cervical Dystonia
DYSPORT™ Clinical & Health Economics Outcomes Registry in Cervical Dystonia
The purpose of the protocol is to determine typical patient response to Dysport in the treatment of adult cervical dystonia (CD).
- Trial name
- ANCHOR-CD (NCT01314365)
- Where
- 45 sites in United States
- Volunteers
- 350 people
- Sponsor
- Ipsen
Early Child Well-being, Parental Stress
Mixed Methods Evaluation of the Pomona Household Universal Grant (HUG) Program
The City of Pomona is launching the Pomona Household Universal Grant (HUG) program in the Summer of 2024. Pomona HUG is a guaranteed income (GI) pilot project that will provide 250 parents/caregivers with children under 5 years…
- Conditions
- Early Child Well-being, Parental Stress, Family Economic Security, Parental/Caregiver Health
- Trial name
- Pomona HUG (NCT06505811)
- Testing
- Guaranteed Income ($500/monthly), Active Comparison ($20/monthly)
- Where
- United States
- Volunteers
- 599 people
- Sponsor
- University of California, Los Angeles
Breastfeeding, Breastfeeding Education
Improved Child Nutrition and Development Through Social Transfers
The goal of this clinical trial is to learn if a conditional social transfer works to improve rates of complementary breastfeeding.
- Conditions
- Breastfeeding, Breastfeeding Education, Breastfeeding Duration, Breastfeeding Continuation
- Trial name
- TENDER (NCT07569172)
- Testing
- Social Transfer
- Where
- Côte d’Ivoire
- Volunteers
- 1,040 people
- Sponsor
- Swiss Tropical & Public Health Institute
Sleep Disorder
Associations of Socioeconomic Adversity and Sleep With Allostatic Load Among Toddlers
A longitudinal study to examine the relationships among sleep characteristics, stress, and child behavior problems in a community sample of toddlers (12-24 months- ages 12-15 months at enrollment) living in socioeconomically…
- Trial name
- NCT03419871
- Testing
- Monitoring Sleep, stress biomarkers
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Non ST Elevation Myocardial Infarction, Unstable Angina
Conservative Non-Invasive Versus Routine Invasive Management in Coronary Artery Bypass Surgery Patients with Non ST Elevation Elevation Acute Coronary Syndrome
Background: Most coronary artery bypass grafts (CABG) are diseased or blocked within 10 years of surgery meaning CABG survivors have an ever increasing risk of recurrent angina, heart attack and death.
- Trial name
- CABG-ACS (NCT01895751)
- Testing
- Invasive management
- Where
- 5 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- NHS National Waiting Times Centre Board
Prostate Cancer
Cost-utility of Focal HIFU vs Prostatectomy
Medico-Economic Randomized Trial comparing Focal HIFU Treatment to Radical Prostatectomy in Patients with Favorable Intermediate Risk Prostate Cancer
- Trial name
- EMERHIT (NCT05710861)
- Testing
- F-HIFU, Radical Prostatectomy
- Where
- 20 sites in France, Guadeloupe
- Volunteers
- 346 people
- Sponsor
- University Hospital, Bordeaux
Miscarriage, Pregnancy Loss
Cost-utility Analysis of Outpatient Manual Vacuum Aspiration Versus Operating Room Electric Aspiration for the Management of First-trimester Miscarriage
The ASPIR study aims to evaluate the cost-utility of outpatient manual vacuum aspiration compared with operating room electric aspiration for the management of first-trimester miscarriage.
- Conditions
- Miscarriage, Pregnancy Loss, First Trimester Pregnancy
- Trial name
- ASPIR (NCT07732231)
- Testing
- Manual vacuum aspiration (MVA), Electric aspiration (EA)
- Where
- France
- Volunteers
- 860 people
- Sponsor
- Nantes University Hospital
Behavior, Health, Flu
Behavioral Economics to Improve Flu Vaccination Using EHR Nudges
This study will be a multisite, cluster randomized, pragmatic trial to evaluate the effectiveness of personalized nudges to clinicians and patients, relative to a control, to increase flu vaccination rates among older adults in…
- Conditions
- Behavior, Health, Flu, Flu Vaccination
- Trial name
- BE IMMUNE (NCT06057727)
- Testing
- Pre-visit patient text messaging, Default pended order, Monthly peer comparison feedback
- Where
- 2 sites in United States
- Volunteers
- 80,039 people
- Sponsor
- University of Pennsylvania