Clinical trials: Health Prevention
Dementia Risk Factors, Prevention
The REMINDER4Care Program for Older Adults Supported by Residential and Daycare Facilities
Dementia incidence is rising, posing a public health challenge, but 45% of cases can be prevented by addressing modifiable risk factors.
- Conditions
- Dementia Risk Factors, Prevention, Cognitive Health
- Trial name
- REMINDER4Care (NCT06922071)
- Testing
- REMINDER4Care
- Where
- Portugal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Obsessive-compulsive Disorders and Symptoms, Obsessive-Compulsive Disorder
Inference-Based Cognitive Therapy Versus Exposure and Response Prevention for Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a highly disabling psychiatric illness, characterized by obsessional thoughts that cause patients to perform time-consuming and distressing compulsive rituals.
- Trial name
- RCT_TOC_16 (NCT03677947)
- Testing
- Exposure and response prevention, Inference-based cognitive therapy
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal
Health Behavior, Noncommunicable Diseases
The LvL UP Trial: Assessing the Effectiveness of a mHealth Intervention
Non-communicable diseases (NCDs), such as cardiovascular disease, diabetes, or cancer, and common mental disorders (CMDs), such as depression or anxiety, represent the primary causes of death and disability worldwide, causing…
- Conditions
- Health Behavior, Noncommunicable Diseases, Mental Health Issue, Lifestyle Risk Reduction
- Trial name
- NCT06592443
- Testing
- LvL UP, LvL UP + MI, Comparison
- Where
- 2 sites in Singapore
- Volunteers
- 1,061 people, healthy volunteers welcome
- Sponsor
- Singapore ETH Centre
Depression, Postpartum, Anxiety Disorders and Symptoms
Feasibility of M-health Version of "What Were We Thinking" Intervention to Promote Maternal Postpartum Mental Health
The purpose of this study is to assess the feasibility, acceptability and preliminary effectiveness of "What Were We Thinking" (WWWT) a psychoeducational intervention -delivered remotely via communication technologies- to prevent…
- Conditions
- Depression, Postpartum, Anxiety Disorders and Symptoms, Maternal Behavior
- Trial name
- NCT04847076
- Testing
- m-health version of WWWT intervention, Treatment as usual
- Where
- 2 sites in Chile
- Volunteers
- 128 people
- Sponsor
- Universidad del Desarrollo
Cancer Awareness and Prevention Education, Breast Cancer Awareness
A Single-Arm Interventional Trial of Pepper- Robot Delivered Cancer Education for Adults With Intellectual Disability
Individuals with Intellectual disability face numerous barriers to cancer education, awareness and screening, including communication challenges, anxiety, and a lack of accessible educational resources.
- Conditions
- Cancer Awareness and Prevention Education, Breast Cancer Awareness, Intellectual Disabilities (F70-F79)
- Trial name
- Pep-SMARTID (NCT07477938)
- Testing
- Robot delivered Education
- Where
- Ireland
- Volunteers
- 25 people
- Sponsor
- National University of Ireland, Galway, Ireland
HIV, Mental Health
Engaging Seronegative Youth to Optimize HIV Prevention Continuum
The focus of this study (Engaging Seronegative Youth to Optimize HIV Prevention Continuum) - will be to stop HIV-related risk acts and to encourage youth at high risk for HIV to adopt antiretroviral medications as treatment and…
- Conditions
- HIV, Mental Health, Substance Use, STI
- Trial name
- NCT03134833
- Testing
- Automated Messaging & Monitoring, Peer Support, Coaching
- Where
- 2 sites in United States
- Volunteers
- 1,478 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Tobacco Dependence
Improving Health for Aboriginal People Through Tobacco Related Research
Aim: To identify barriers and facilitators in the uptake of smoking cessation pharmacotherapies, tobacco prevention, doctor visits, smoking amongst youth, community held health priorities and barriers to research in Aboriginal…
- Trial name
- NCT01735448
- Testing
- Focus group, One-on-one interviews, Survey
- Where
- 3 sites in Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Queen Elizabeth Hospital
Depressive Symptoms, Allostatic Load
Our Voices Matter: Intervention for Depression in Youth
Over 15 million people participated in racial justice protests nationwide during 2020-2021 spotlighting activism as a collective tool against structural racism and discrimination (SRD).
- Conditions
- Depressive Symptoms, Allostatic Load, Metabolic Syndrome
- Trial name
- OVM (NCT07216326)
- Testing
- Racial Justice Activism Intervention ARM, Adulting 101- Control Arm
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Sexually Transmitted Infections (Not HIV or Hepatitis), HIV Infections
IMARA for Black Male Caregivers and Girls Empowerment (IMAGE)
The scientific premise of this research is that individual, interpersonal, and structural factors impact Black girls' sexual reproductive health outcomes (sexually transmitted infection (STI) and Human Immunodeficiency Virus…
- Conditions
- Sexually Transmitted Infections (Not HIV or Hepatitis), HIV Infections, Sexual Behavior
- Trial name
- IMAGE (NCT06266416)
- Testing
- IMARA for Black Male Caregivers and Girls Empowerment, Time-matched control program
- Where
- United States
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Myocardial Infarction (MI), Tobacco Use
Telegram Messenger Support for Smoking Cessation After Heart Attack
This randomized controlled trial will evaluate whether a 6-month behavioral intervention delivered via Telegram messenger increases smoking cessation rates in patients after myocardial infarction (MI).
- Conditions
- Myocardial Infarction (MI), Tobacco Use, Smoking Cessation
- Trial name
- TELEGRAM-MI (NCT07230249)
- Testing
- Telegram-based Smoking Cessation Support, Standard Care (in control arm)
- Where
- Russia
- Volunteers
- 142 people
- Sponsor
- ITMO University
Vertical Transmission of Infectious Disease, HIV Infections
Community Health Workers and Prevention of Mother-to-Child HIV Transmission in Tanzania
The investigators implemented and evaluated a pilot program in Shinyanga Region, Tanzania to bring prevention of HIV services to communities using community health workers (CHWs).
- Trial name
- NCT03058484
- Testing
- Community Health Worker intervention
- Volunteers
- 1,830 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Obesity
Translational Obesity Research
The proposed project takes an innovative approach to childhood obesity prevention, for which there currently no evidence-based programs, and for which results of current trials have produced mainly short-term or disappointing…
- Trial name
- Pathways (NCT00787709)
- Testing
- Pathways
- Where
- United States
- Volunteers
- 1,005 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Stroke, Depression
Mobile Technologies and Post-stroke Depression
The recent development of acute phase treatments has dramatically improved stroke functional outcome but post-stroke neuropsychiatric disorders, notably post-stroke depression, continue to contribute to the heavy burden of…
- Trial name
- MOTIV-POSDEP (NCT04043052)
- Testing
- Psychological evaluation, Functional evaluation, Biological assessment
- Where
- 5 sites in France
- Volunteers
- 401 people
- Sponsor
- University Hospital, Bordeaux
Diabetes Mellitus
A Study on Effect of Health Promotion for Prevention NIDDM in People With Prediabetes
OBJECTIVE - The role of health promotion for patients with impaired fasting glucose on preventing or delay the progression of diabetes mellitus has not been widely investigated in Taiwan.
- Trial name
- NCT00257218
- Testing
- Life style modification
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Benign Prostatic Hyperplasia (BPH)
The Evaluation of Banana Flower Stamens Extract on Prevention of Benign Prostatic Hyperplasia in Adults
To assess the evaluation of banana flower stamens extract on prevention of benign prostatic hyperplasia in adults
- Trial name
- NCT04266418
- Testing
- Banana flower stamens extract
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Ethnic Group, Young Adults
Diabetes Prevention in Prediabetic Patients
This study will evaluate the feasibility and efficacy of two interventions of lifestyle ( intensive and less intensive) to prevent diabetes in patients from Ethiopian origin, aged 25 to 55 years old with prediabetes living in…
- Conditions
- Ethnic Group, Young Adults, Prediabetes, Community Health Services
- Trial name
- DPEP (NCT01659697)
- Testing
- intensive lifestyle counseling
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Meir Medical Center
HPV Vaccination, Uptake Vaccination
PREVENT HPV -Related Cancers Trial
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Uptake Vaccination, Series Completion
- Trial name
- NCT07217145
- Testing
- PREVENT
- Where
- United States
- Volunteers
- 1,455 people, healthy volunteers welcome
- Sponsor
- University of Utah
Sexually Transmitted Diseases
The Effect of Education Given to Reproductive Age Women by Teach Back Method on Behaviors
Sexually transmitted infections (STIs) are an important public health problem as they affect more than 1 million people worldwide every day.
- Trial name
- NCT05544851
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Hemophilia A
Effects of Emicizumab vs. Factor VIII Prophylaxis on Joint and Bone Health in Severe Hemophilia A
The investigators propose to study longitudinal joint and bone density changes in patients with severe Hemophilia A. Per current standard of care, most patients are on prophylactic FVIII replacement therapy intravenously several…
- Trial name
- EmiMSK (NCT04131036)
- Testing
- assessment of joint health and bone density
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Washington Institute for Coagulation
Alcohol Misuse, Alcohol Prevention
Effectiveness Trial of an mHealth Intervention to Help Parents Prevent Early Onset Alcohol Use
Many parents are permissive about children's alcohol use (e.g., they allow sips of alcohol); this leniency increases the risk that children will experience serious alcohol-related consequences as they become teenagers.
- Trial name
- BIPAS Alcohol (NCT07683702)
- Testing
- BIPAS Alcohol
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- RTI International
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