Clinical trials: Healthy, open to volunteers
Healthy Volunteer
NEURO-IS: Neurophysiology of Inner Speech Across Neurotypical Participants.
The purpose of this study is to investigate the brain activity associated with two common inner experiences: visual mental imagery (mentally seeing objects or actions) and inner speech (experiencing language without speaking out…
- Trial name
- NEURO-IS (NCT07885020)
- Testing
- Inner Experience Induction Tasks and hdEEG
- Where
- Belgium
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Liege
Femoro-acetabular Impingement
Single-center Comparative Study of Variation in Acetabular Anteversion According to Pelvic Tilt in Patients With Femoro-acetabular Impingement and Healthy Volunteers.
The main objective is to show that the upper acetabular anteversions calculated in standing, sitting, sitting hip in maximum flexion and supine positions are lower in patients with symptomatic DWI compared to healthy volunteers.
- Trial name
- VARIA-CFA (NCT05678894)
- Testing
- Scanner and EOS imaging
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Asthma, Atherosclerosis
Study of the Effect of Innate on the Inflammatory Response to Endotoxin
Background: Innate immunity is the process by which white blood cells and other parts of the immune system sense and respond to potential infections by causing an inflammation.
- Conditions
- Asthma, Atherosclerosis, Metabolic Syndrome, Insulin Resistance
- Trial name
- NCT01143480
- Where
- United States
- Volunteers
- 725 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Healthy
Neural Adaptations to Metronome-Paced Strength Training
The aim of the study is to investigate the effects of incorporating variability within Resistance Training (RT) methods on the neural adaptations along the corticospinal tract and on neuromuscular function.
- Trial name
- NCT06532786
- Testing
- Fractal Paced, Isochronous Paced, Self Paced
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Healthy
Safety, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of Ascending Doses BCD-261 in Healthy Subjects
The goal of this clinical trial is to investigate the safety, tolerability, pharmacodynamics, pharmacokinetics, and immunogenicity of BCD-261 after single subcutaneous injection at ascending doses and proposed therapeutic doses…
- Trial name
- NCT06715540
- Testing
- BCD-261, dose 1, BCD-261, dose 2, BCD-261, dose 3
- Where
- Russia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Biocad
High Altitude Effects
Measurement of Cardiopulmonary Variables After Acute Exposure to High Altitude
As altitude increases, the availability of oxygen in the air decreases, and just to compensate for this lack, the body increases cardiac and respiratory work and changes blood pressure.
- Trial name
- NCT05769140
- Where
- Italy
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Centro Cardiologico Monzino
Irritability
Study Brain Mechanisms of Frustration With Magnetoencephalography in Healthy Volunteers
Background: Irritability can be defined as an unusually strong response to frustration; these responses may include severe temper outbursts and a constant grumpy mood.
- Trial name
- NCT06484088
- Testing
- Frustration task
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Heart Disease
Diet and Active Lifestyle - Yuuyaraq (The Yup'ik Way of Life)
Heart disease is the leading cause of death for Alaska Native men and the second leading cause of death (after cancer) among women and Alaska Native people overall.
- Trial name
- DAiLY (NCT06629610)
- Testing
- DAiLY
- Where
- 2 sites in United States
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Healthy Volunteers
A Study of LY4178256 in Healthy Participants
The main purpose of this study is to evaluate how well LY4178256 is tolerated and what side effects may occur in healthy participants.
- Trial name
- NCT07698210
- Testing
- LY4178256
- Where
- 2 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Stress, Healthy Subjects
The Effects of Chicory Root-derived Prebiotic on Mood and Stress Responsiveness in Healthy Adults With Mild to Moderate Levels of Stress and Anxiety
Emerging evidence from preclinical research suggests that prebiotic fibres may play a beneficial role in supporting mental health through modulation of the gut-brain axis-a complex communication network linking the…
- Conditions
- Stress, Healthy Subjects, Anxiety, Mild to Moderate
- Trial name
- PRIME (NCT07058324)
- Testing
- Prebiotic fiber
- Where
- Germany
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Beneo-Institute
Healthy Volunteers
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of KL0011034 Injection Administered by Continuous Infusion in Healthy Adult Subjects
This study is a randomized, double-blind, propofol position-controlled trial, evaluating the safety, tolerability, and pharmacodynamic of continuous infusion of KL0011034 injection compared with propofol injectable emulsion for…
- Trial name
- NCT07828470
- Testing
- KL0011034 injection, propofol injectable emulsion
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hunan Kelun Pharmaceutical Co., Ltd.
Healthy
A Study to Learn About the Medicine Called PF-08653944 in People With and Without Reduced Liver Function
This study is being done to learn more about an investigational medicine called PF-08653944. The goal is to understand how the body handles the medicine and to check its safety after a single dose.
- Trial name
- NCT07519135
- Testing
- PF-08653944
- Where
- 3 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
A Study in Healthy Men to Test How Well Different Doses of BI 3776528 Are Tolerated
The trial aims to study the safety, tolerability, and pharmacokinetics of single and multiple rising doses of BI 3776528.
- Trial name
- NCT06745297
- Testing
- BI 3776528, short-acting benzodiazepine
- Where
- Germany
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Non-contrast Enhanced Cardiac Magnetic Resonance Normal Values and Imaging Protocols
One of the main problems in cardiac magnetic resonance (MR) investigations is the strong dependence of the achieved image quality on optimal settings of sequence parameters and anatomical and physiological situations and it is…
- Trial name
- CMR-TECH (NCT01728597)
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Cerebral Palsy, Hemiparesis; Poststroke/CVA
Characterization of Muscle Activity During a Surface EMG-controlled Rehabilitation Game
The aim of this pilot study is to evaluate muscular activity during a single session of surface electromyography controlled exergame (muscle activation, number of contraction…) in cerebral palsy kids, hemiparetic adults and…
- Conditions
- Cerebral Palsy, Hemiparesis; Poststroke/CVA, Healthy (Controls)
- Trial name
- CONTRACTIV-1S (NCT07838688)
- Testing
- Surface electromyography (sEMG)-controlled rehabilitation game
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Healthy
Assessment of a New Tool to Measure Tongue Muscle Function
The Iowa Oral Performance Instrument (IOPI) is currently the reference tool for assessing tongue muscle function, measuring the pressure exerted by the tongue on an air-filled bulb.
- Trial name
- TOM1 (NCT07625761)
- Testing
- TOngue Manometer (TOM) device, IOPI
- Where
- Belgium
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Eating Behavior, Dietary Behavior
Dual-Label Intervention to Promote Low-Carbon and Healthy Food Choices in a University Cafeteria
This study aims to evaluate whether a dual-label intervention, combining carbon -coded footprint color labels and calorie information, can promote low-carbon and healthier food choices among university students in a real-world…
- Trial name
- NCT07531524
- Testing
- Carbon and Calorie label
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lina Zhang
Emotion Management Skills, Lifestyle, Healthy
The Impact of Enhanced Music & Natural Visuals on Emotional Health
The investigators are conducting research on factors related to the self-regulation of mood and arousal states across a range of everyday activities as well as different levels of stress.
- Conditions
- Emotion Management Skills, Lifestyle, Healthy, Lifestyle Intervention, Recovery
- Trial name
- NCT07676110
- Testing
- soundBrilliance software application - Emotional Health
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- soundBrilliance LLC
HIV -1 Infection
Safety Study of MucoCept-CVN
MucoCept-CVN uses a Lactobacillus strain native to the human vagina that is modified into a live biotherapeutic product (LBP) that continuously expresses a potent anti-HIV drug.
- Trial name
- NCT07181486
- Testing
- Live Biotherapeutic Product L. jensenii 1153-1666
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Craig Cohen, MD, MPH
Friedreich Ataxia, Cardiomyopathies
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ATI-105 in Healthy Adults
The goal of this clinical trial is to learn how ATI-105 administered to healthy participants at works in the body at different doses and with or without food.
- Conditions
- Friedreich Ataxia, Cardiomyopathies, Central Nervous System Diseases, Neuromuscular Diseases
- Trial name
- NCT07869654
- Testing
- ATI-105
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Adjuvia Therapeutics, Inc.
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