Clinical trials: Healthy Aging, open to volunteers
Serious Mental Illness, Older Adults
A Pilot Randomized Controlled Trial of the Hopeful and Healthy Living Program
The goal of this clinical trial is to learn if a novel psychosocial intervention is effective in helping adults over 50 with serious mental illness (SMI) increase their social connections and participate in more healthy lifestyle…
- Trial name
- (HHL) (NCT06940843)
- Testing
- Hopeful and Healthy Living (HHL)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Boston University Charles River Campus
Frailty in Older Adults, Intrinsic Capacity
Optimizing INtrinsic Capacity for Functional INdependence and to Impede FrailTY in Older Adults: Adaptation of the WHO-ICOPE for Healthy Ageing in Singapore
The goal of this intervention study is to screen and identify frailty and decline in intrinsic capacity (physical and mental capacities) in community-dwelling older adults in Singapore, and to evaluate whether early…
- Conditions
- Frailty in Older Adults, Intrinsic Capacity, Age-related Functional Decline, Healthy Ageing
- Trial name
- INFINITY-ICOPE (NCT07477561)
- Testing
- INFINITY-ICOPE programme
- Where
- Singapore
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sengkang General Hospital
Mild Dementia, Aging Well
Transcranial Pulse Stimulation of the Brain
This study will investigate transcranial pulse stimulation (TPS) as a method of enhancing cognitive and neural function. The study team will apply this low intensity, magnetically pulse technology to key brain regions in a…
- Trial name
- NCT05910619
- Testing
- Neurolith Transcranial Pulse Stimulation Active
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida
Subjective Cognitive Concerns, Mild Cognitive Impairment
Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD
The goal of this study is to objectively test one's sense of smell, called olfaction, in participants with Subjective Cognitive Concerns (SCC), Mild Cognitive Impairment, Mild Behavioral Impairment (MBI), and age-matched…
- Conditions
- Subjective Cognitive Concerns, Mild Cognitive Impairment, Mild Behavioral Impairment, Healthy Aging
- Trial name
- NCT05881239
- Testing
- AROMHA Brain Health Test
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obesity, Menopause
Aging Well: Targeting Obesity With GLP-1 Agonists to Enhance Physical and Vascular Health in Postmenopausal Women
In postmenopausal women, obesity increases the risk of physical function decline, premature aging, and vascular dysfunction. Semaglutide and tirzepatide are potent obesity medications.
- Trial name
- NCT07057310
- Testing
- semaglutide or tirzepatide, Lifestyle modification intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Imagery (Psychotherapy), Postural Control
The Effect of Motor Image Training on Balance Performance in Geriatric Individuals
The goal of this study [type of study: clinical trial] is to was planned to investigate the effect of motor imagery training given to geriatric individuals with action observation on their balance performance and to compare these…
- Conditions
- Imagery (Psychotherapy), Postural Control, Postural Balance, Virtual Reality Therapy
- Trial name
- NCT06056180
- Testing
- Balance Training, Motor İmagery Training, Action Observation Training
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Muğla Sıtkı Koçman University
Aging, Aging Disorder
Aging Well Together - 'Getting to Know You Better': Characterization of Health FACTors in People Advancing in AGE
In order to implement effective actions to prevent the loss of autonomy in older adults, which has become a major issue, a crucial first step is to identify the conditions that influence it.
- Conditions
- Aging, Aging Disorder, Aging, Healthy
- Trial name
- BVE-FACTAGE (NCT07651527)
- Testing
- Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Menopause, Perimenopausal Disorder
Virtual perI-/Menopause Registry of AusTrALia
13 million (50.7%) Australians are born with ovaries, 14% (~3 million) are currently aged 40-59 yrs, \& all such who live to midlife will experience menopause, defined as >12 months without a period.
- Conditions
- Menopause, Perimenopausal Disorder, Postmenopausal Symptoms, Health Knowledge, Attitudes, Practice
- Trial name
- VITAL (NCT06487130)
- Testing
- N/A Observational Registry
- Where
- Australia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Bespoke Clinical Research
Exercise Adherence, Healthy Aging
Effectiveness of a Smartphone Chatbot to Improve Exercise Adherence in Older Adults
This randomized controlled trial aims to evaluate the effectiveness of a smartphone-based chatbot in improving adherence to a 12-week home-based multicomponent exercise program in community-dwelling older adults.
- Trial name
- EXEBOT (NCT07832097)
- Testing
- Chatbot-Supported Home-Based Exercise Program, Paper-Based Home Exercise Program Mostrar más líneas
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Mild Neurocognitive Disorder, Healthy Aging
tFUS for Memory in mNCD and Healthy Adults
Dementia is an ongoing and growing public health crisis in the US and worldwide. The purpose of this study is to examine a form of noninvasive brain stimulation called transcranial focused ultrasound (tFUS) to the hippocampus…
- Trial name
- NCT06718140
- Testing
- Transcranial Focused Ultrasound
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Aging, Alzheimer Disease
Lifestyle for the BRAin Health - Nutrition and Exercise Training Intervention
Due to the increasing incidence of dementia and the lack of causal treatment, non-pharmacological interventions represent an attractive and effective therapeutic strategy of neurodegenerative diseases, such as Alzheimer's…
- Conditions
- Aging, Alzheimer Disease, Life Style, Healthy, Exercise
- Trial name
- LIBRA-NET (NCT06986096)
- Testing
- Aerobic-strength training and nutritional counseling, Cognitive training and stretching.
- Where
- Slovakia
- Volunteers
- 40 people
- Sponsor
- Slovak Academy of Sciences
Mild Cognitive Impairment
CBD for Individuals at Risk for Alzheimer's Disease
This is a double-blind, randomized controlled trial designed to test the effects of cannabidiol (CBD) on validated biomarkers of Alzheimer's disease (AD) progression, and behavioral, neurocognitive, and clinical measures, with…
- Trial name
- NCT05822362
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- University of Colorado, Denver
Aging, Aging Well
Adjuvant Nitrate to Boost Exercise-induced Health Benefits in Older Adults
Aging-related functional declines are thought to be caused by hallmark biological processes that ultimately manifest in physical, mental, and metabolic impairments to compromise intrinsic capacity and healthspan.
- Conditions
- Aging, Aging Well, Healthy Aging
- Trial name
- BOOST-X (NCT07572266)
- Testing
- Nitrate enriched beetroot juice, Nitrate depleted beetroot juice, 12 week of combined exercise training
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Florida Institute for Human and Machine Cognition
Healthy Aging
Adopting a Health-social Partnership Program to Promote Health and Self-care Management Among Older Adults in the Community
Hong Kong has notably the longest life expectancy in the world. Ever-increasing demand and challenges are posing to the healthcare, social welfare, and elderly care service system.
- Trial name
- NCT05621720
- Testing
- Case management, Social control call and usual are
- Where
- Hong Kong
- Volunteers
- 788 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Parkinson's Disease (PD), Healthy Aging
Exoskeleton-Assisted Mobility in Aging and in Parkinson's Disease
This study will evaluate whether a wearable robotic exoskeleton can improve mobility, balance, and walking in healthy older adults and in individuals living with Parkinson's disease, populations at high risk of falls and mobility…
- Trial name
- NCT07567482
- Testing
- Exoskeleton
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Centre intégré de santé et de services sociaux de l'Outaouais
Healthy Aging, Digital Health Literacy
Digital Technology for Active and Healthy Ageing in Taiwan
Taiwan is entering a super-aged society in 2025, with more than 20% of the population aged 65 years or older. This rapid demographic shift, combined with increasing rates of chronic diseases, frailty, and dementia, has created…
- Trial name
- NCT07232667
- Testing
- Geneactiv, iMED Mobile Health Platform, iCue
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Healthy Aging, Sarcopenia
Plant-based Diets and Healthy Aging
This prospective study investigates the health effects of vegetarian and plant-based diets in middle-aged and older adults in Taiwan, specifically, recruiting 5000 Tzu Chi volunteers.
- Conditions
- Healthy Aging, Sarcopenia, Frailty, Cognitive Decline
- Trial name
- TCAS (NCT07151365)
- Where
- Taiwan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Aging Well, Aging
The Role of Brain Lactate Metabolism in Neuroprotection During Healthy Aging
The brain's primary source of fuel is glucose. Unfortunately, the brain's ability to use glucose declines during normal aging. This decline in brain glucose metabolism makes it vulnerable to cognitive impairment and Alzheimer's…
- Trial name
- NCT07731451
- Testing
- Sodium lactate infusion, Exercise-induced hyperlactatemia
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Aging, Healthy Aging
FAXAGE: Fasting And Exercise To Slow Aging In Humans
FAXAge is a randomized controlled trial investigating the effects of fasting and exercise on human aging. 240 participants over the age of 65 will be divided into 4 groups - an exercise group, a fasting group, a combined exercise…
- Conditions
- Aging, Healthy Aging, Aging Frailty
- Trial name
- FAXAGE (NCT07207044)
- Testing
- Exercise - Strength + Cardio, Time-restricted feeding, Time-restricted feeding + Exercise
- Where
- Denmark
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Aging, Older Adults
Supplement and Exercise Effects on Stationary Immunity and Health in Older Adults
The goal of this clinical trial is to learn whether a natural-origin nutritional supplement, combined with a moderate-intensity functional exercise program, can improve seasonal immunity, perceived health, and oxidative stress in…
- Trial name
- NCT07251244
- Testing
- Group 1: Exercise + nutritional supplement (EXNS)
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Valencia