Clinical trials: Healthy Control Group
Contraception
To Investigate the Pharmacological Effects, Drug Blood Levels and Safety of an Intrauterine System Releasing the Study Drug BAY1007626 in Comparison to Mirena and Jaydess in Healthy Young Women Treated for 90 Days to Determine the Drug Dose for Further Development
Investigation of pharmacological effects, drug blood levels and safety of an intrauterine system releasing the study drug BAY1007626 in comparison to Mirena and Jaydess in healthy young women treated for 90 days to determine the…
- Trial name
- NCT02490774
- Testing
- BAY1007626, Jaydess, Mirena
- Where
- 7 sites in Germany, Netherlands and 1 more
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
A Study to Investigate Safety, Tolerability and Pharmacokinetics of AZD1446 Administered for 4 Weeks in Elderly Healthy Volunteers
This study is designed to evaluate the safety, tolerability and pharmacokinetics (PK) of two doses of AZD1446 or placebo in subjects when given for 4 weeks.
- Trial name
- NCT00997308
- Testing
- AZD1446
- Where
- Sweden
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Autism, Autism Spectrum Disorder
Maternal Risk Factors for Autism Spectrum Disorders: A Case-Control Approach
New research suggests that about 1 in 8 children may be diagnosed with an autism spectrum disorder (ASD) in the United States. This could be due to several reasons which remain unknown.
- Conditions
- Autism, Autism Spectrum Disorder, Autistic Disorder, Pregnancy Related
- Trial name
- NCT05453708
- Testing
- Survey
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Walden University
Anesthesia, Anesthesia, Local
A Study in Healthy Male Volunteers to Investigate the Safety and Tolerability of a Single Dose of Neosaxitoxin Alone and in Combination With Bupivacaine (With and Without Epinephrine) for Brachial Plexus Blockade
Neosaxitoxin is a new compound that is in clinical development as local anesthetic for surgical anesthesia and postoperative analgesia.
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia
- Trial name
- NCT03399435
- Testing
- Neosaxitoxin combined with bupivacaine low and epinephrine (T1), Bupivacaine low combined with epinephrine (C1), Bupivacaine high combined with epinephrine (C2)
- Where
- Netherlands
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Stroke, Stroke, Acute
Phase 1 Study to Assess AER-271
The objective of this Phase 1 trial is to assess the safety, tolerability and pharmacokinetics of AER-271 in health subjects.
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic
- Trial name
- NCT03804476
- Testing
- AER-271
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aeromics, Inc.
Healthy
Evaluation of Skin Irritation Potential With PF-06700841 Cream Formulation Using Negative Control in Adult Japanese Healthy Participants
This is a Phase 1, single center, randomized, vehicle and white petrolatum controlled, evaluator blinded study to assess the skin irritation potential with a range of concentrations of PF-06700841 cream including vehicle and…
- Trial name
- NCT03916250
- Testing
- PF-06700841 cream, White petrolatum
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Aging
Using Teleneuropsychology to Optimize Cognition in Healthy Aging: the Web-based Breakfast Game
Executive control processes involve initiate, coordinate, synchronize, and regulate elemental cognitive functions for the conduct of goal-directed behavior.
- Trial name
- NCT05506852
- Testing
- Web-based training strategy, Web-based regular training (no strategy)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Columbia University
Stroke, Healthy Control
Perceived Social Support in Adult Stroke
Given the limited evidence in the literature regarding the effect of perceived social support on life satisfaction and social participation in adults with stroke, this study aimed to investigate the effect of perceived social…
- Trial name
- NCT07390526
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Pharmacokinetics of Alefacept
A Study of Pharmacokinetics and Safety of Alefacept in Caucasian and Japanese Healthy Volunteers
The objective of this study is to compare the pharmacokinetic and pharmacodynamic properties and safety profile of alefacept in Caucasian and Japanese healthy subjects
- Trial name
- NCT00653822
- Testing
- alefacept
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Healthy
The Effect of Altered Gravity Condition on Postural Control
The scientific goal of this experiment is to evaluate changes in balance control in response to microgravity during reactive balance tasks.
- Trial name
- POSTURGRAV (NCT02517229)
- Testing
- Parabolic flight, balance control measurements, electromagnetic maneuverable postural platform
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy
Safety, Tolerability and Pharmacokinetics of BIBW 2948 BS in Healthy Male Volunteers
Study to investigate safety, tolerability, and pharmacokinetics of BIBW 2948 BS
- Trial name
- NCT02214901
- Testing
- BIBW 2948 BS for oral inhalation
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Non Alcoholic Fatty Liver Disease, Lifestyle
Non Alcoholic Fatty Liver Disease: Nutritional Epidemiology and Lifestyle Medicine
The study is an open-label intervention non pharmacological Cohort Study without control arm in patients with Non Alcoholic Fatty Liver Disease (NAFLD) and in healthy subjects.
- Conditions
- Non Alcoholic Fatty Liver Disease, Lifestyle, Diet Modification
- Trial name
- SEELN (NCT03300661)
- Testing
- Mediterranean Style
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Brescia
COVID-19 Virus Infection
Clinical Trial to Evaluate the Efficacy, Immunogenicity and Safety of the Inactivated SARS-CoV-2 Vaccine (COVID-19)
This is a randomized, double blind, placebo parallel-controlled phase III clinical trial to evaluate the efficacy, immunogenicity and safety of the inactivated SARS-CoV-2 Vaccine (Vero cell) in Argentine healthy population aged…
- Trial name
- NCT04560881
- Testing
- Inactivated SARS-CoV-2 vaccine (Vero cell)
- Where
- 4 sites in Argentina
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Laboratorio Elea Phoenix S.A.
Pain
The Safety and Tolerability of PF-05089771 Will be Investigated in Healthy Subjects Over a 14 Day Dosing Period.
The purpose of the study is primarily to determine the safety and toleration and pharmacokinetics of PF-05089771 following escalating multiple doses lasting for 14 days.
- Trial name
- NCT01365637
- Testing
- PF-05089771
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pfizer
Cognitive Function and Mood, Cerebral Blood Flow
The Effects of Resveratrol Supplementation on Cognition, Cerebral Blood Flow, Microbiota and Systemic Inflammation.
Previous research shows that a diet high in fat has harmful effects on gut health. This increases the chance of developing obesity-related diseases (such as type 2 diabetes) and disrupts cognition and mood.
- Conditions
- Cognitive Function and Mood, Cerebral Blood Flow, Systemic Inflammation, Gut Microbiota
- Trial name
- NCT03448094
- Testing
- Resveratrol
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Rheumatoid Arthritis, Healthy Control
Adipokines as Predictors of Foot Function, Pain, and Disability in Patients With Rheumatoid Arthritis
Significant increase in the levels of serum adiponectin, ADA, and hsCRP was reported in all RA patients compared to controls. Compared to patients with early RA, the increase in these markers significantly correlated with disease…
- Trial name
- NCT04036669
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- King Saud University
Healthy, Breast Cancer
Informed Decision Users of the Health System and Participation in Organized Screening for Breast Cancer
The aim of this study is to assess the impact of a decision aid leaflet on the participation of women invited to participate in the French national breast cancer screening program.
- Trial name
- DECIDEO (NCT02093039)
- Testing
- decision aid group
- Where
- France
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Institut de Cancérologie de la Loire
Hamstring Tightness
Dynamic Oscillatory Stretch Technique Versus Static Stretching In Reduced Hamstring Flexibility
This study compared the effects of dynamic oscillatory stretch technique (DOS) and static stretching (SS) technique in order to improve hamstring extensibility in healthy individuals with asymptomatic hamstring tightness.
- Trial name
- NCT03885557
- Testing
- Group I Experimental DOS, group II SS group
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Gut Microbiome, Glucose Control
Exploring Glycemic Responses Through Continuous Monitoring in a Healthy Population
PREDICT REFINE is a sub-study of PREDICT 3 with the primary aim of exploring glycemic responses through continuous glucose monitoring in a healthy population.
- Trial name
- NCT06900439
- Testing
- Dietary Intervention
- Where
- United Kingdom
- Volunteers
- 1,189 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Prostate Cancer Cured, Healthy Population Control
Study of Geriatric Patients Aged 75 Years or Older Treated and Cured for Localized Prostate Cancer: Case-control Study
This is a multicenter pilot study, proposed for cases and controls 3 departments in France. Cases are cured patients who have had prostate cancer for at least 10 years.
- Trial name
- PROGE (NCT01797692)
- Testing
- geriatric assessment
- Where
- 5 sites in France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Centre Francois Baclesse
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