Clinical trials: Healthy Control Group
Deglutition Disorder, Healthy
Electrical Muscle Stimulation to Aid Swallowing in Dysphagia
The purpose of this study is to determine the feasibility of using extrinsic laryngeal muscle stimulation to elevate the larynx in a manner similar to that which occurs during normal swallowing.
- Trial name
- NCT00001936
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy Volunteer
MS PATHS Normative Sub-Study
The primary objective of this study is to determine the normative range of brain volume and brain volume change in healthy control (HC) participants whose age, race, and gender distribution is approximately matched to the age…
- Trial name
- NCT02996084
- Where
- 6 sites in United States, Germany and 1 more
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Biogen
Diabetes, Diabetes Mellitus, Type 2
Effect of Liraglutide on Heart Frequency in Healthy Volunteers
This trial is conducted in the United States of America (USA). The aim of this trial is to investigate if liraglutide effects the QTc interval. Moxifloxacin (Avelox®) is administered as positive control.
- Trial name
- NCT01516255
- Testing
- liraglutide, moxifloxacin, electrocardiogram (ECG)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Healthy
Effect of Meloxicam Tablets on Bleeding Time in Healthy Subjects
The primary purpose of this study was to evaluate the effect of meloxicam tablets (7.5, 15 mg and 30 mg) with meloxicam placebo.
- Trial name
- NCT02183155
- Testing
- Meloxicam - low, Meloxicam - medium, Meloxicam - high
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Chronic Neck Pain, Healthy (Controls)
Accessory Inspiratory Muscles in Chronic Neck Pain
This cross-sectional case-control study aims to investigate the ultrasonographic structural and functional characteristics of accessory inspiratory muscles in individuals with chronic non-specific neck pain and compare them with…
- Trial name
- AIM-CNP (NCT07782099)
- Testing
- Diaphragm Ultrasonography, Anterior Scalene Muscle Ultrasonography, Upper Trapezius Muscle Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Kocaeli Sağlık ve Teknoloji Üniversitesi
Cardiodynamics, Safety
Study of Selexipag and Its Metabolite ACT-333679 on Cardiac Repolarization in Healthy Male and Female Subjects
This is a single-center, double-blind, randomized, placebo- and positive-controlled, double-dummy, parallel-group, multiple-dose, up-titration study with a nested cross-over comparison between moxifloxacin and placebo in healthy…
- Conditions
- Cardiodynamics, Safety, Tolerability, Pharmacokinetics
- Trial name
- NCT02206204
- Testing
- selexipag, moxifloxacin
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Actelion
Pulmonary Disease, Chronic Obstructive
Investigation of Chronic Obstructive Pulmonary Disease (COPD) Phenotypes and Endotypes in China
This is a non-drug interventional cohort study, which aims to investigate the clinical, radiological and biological factors associated with disease progression in COPD in China.
- Trial name
- NCT04853225
- Testing
- Prospective observational cohort study
- Where
- 41 sites in China
- Volunteers
- 2,005 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Torsades de Pointes
A Study to Evaluate How VI-0521 Affect Cardiac Repolarization in Healthy Male and Female Volunteers
Determine whether VI-0521 has an effect on the electrical activity of the heart in healthy subjects. Find out how much VI-0521 is in the blood and any potential side effects on ECG's of healthy subjects after taking the study…
- Trial name
- TQT (NCT00839891)
- Testing
- VI-0521
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Healthy
A Multiple Ascending Dose Study of KBP-7072 in Healthy Subjects
This is a randomized, single-blind, placebo-controlled, sequential parallel-group and multiple ascending dose (MAD) study to evaluate the safety, tolerability and pharmacokinetics of KBP 7072 in healthy subjects.
- Trial name
- NCT02654626
- Testing
- KBP-7072
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- KBP Biosciences
Musculoskeletal Physiology, Healthy
Postural Control in the Elderly
This study will examine loss of balance in the elderly. Falls due to balance problems are a major health issue in older people, often resulting in bone fractures and other bodily injuries, and functional decline.
- Trial name
- NCT00059501
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Migraine
Single Ascending Dose Study to Investigate the Safety and Pharmacokinetics of XC101-D13H in Healthy Adult Subjects
This is a randomized, double-blind, placebo-controlled, parallel-group single ascending dose (SAD) study. There are 4 cohorts of 8 subjects (8 active and 2 placebo) planned for evaluation under fasting conditions.
- Trial name
- NCT04104399
- Testing
- XC101-D13H
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Xoc Pharmaceuticals
Neurological Disorder, Healthy Control
Protective Genetic Factors Against Neurological Diseases
NIH Precision Medicine Initiative, started in May 2018, will enroll one million people through an online portal. It hopes to identify genetic variants affecting a variety of human phenotypic outcomes.
- Trial name
- NCT03914599
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Healthy
Effect of ATI-7505 on Gastrointestinal Transit in Healthy Volunteers
This is a pharmacodynamic study in healthy volunteers to determine the effects of a new 5-HT4 agonist on gastric, small bowel and colonic transit.
- Trial name
- NCT01094821
- Testing
- ATI-7505
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy Adult Participants
REM Enhancement Sleep Technology for Well-being, Emotion, and Life Lift
This study aims to explore the efficiency of a digital, Smartphone-delivered intervention for improving the quality of REM sleep on the mental health, emotion regulation and overall life quality of users.
- Trial name
- RESTWELL (NCT07589114)
- Testing
- Mobile smartwatch application.
- Where
- 2 sites in Romania
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Healthy
Study to Determine Tolerability After Intravenous Administration of BIBN 4096 BS in Healthy Male and Female Volunteers
The objective of the present study is to obtain information about the safety, tolerability and pharmacokinetics of BIBN 4096 BS after single intravenous administration of increasing doses in healthy male and female volunteers
- Trial name
- NCT02198352
- Testing
- BIBN 4096 BS - in single rising doses
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Effects of Chronic Acid-Base Changes on Ventilatory and Perceptual Responses
Approximately 30% of people aged 65 years and older experience breathlessness (perceived respiratory difficulty) during daily activity.
- Trial name
- NCT00946933
- Testing
- NH4Cl (ammonium chloride)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen's University
Obsessive Compulsive Disorder
Neural Mechanisms of CBT Response in Hoarding Disorder
The purpose of this research is to measure changes in brain activity with functional magnetic resonance imaging (fMRI) before and after cognitive-behavioral therapy for compulsive hoarding.
- Trial name
- NCT01956344
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Healthy Aging
The Effect of Training on Brain Activity During Postural Tasks in Older Adults
Older people show deficits in dynamic weight-shifting, as the investigators found that more time is needed to perform weight-shifts and the movements became less fluent and accurate in older versus younger adults.
- Trial name
- NCT04594148
- Testing
- Weight-shift training
- Where
- Belgium
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Communication Disorder, Healthy
Central Mechanisms in Speech Motor Control Studied With H215O PET
Positron Emission Tomography (PET) is a technique used to investigate the functional activity of the brain. The PET technique allows doctors to study the normal biochemical and metabolic processes of the central nervous system of…
- Conditions
- Communication Disorder, Healthy, Stuttering, Tourette Syndrome
- Trial name
- NCT00001308
- Where
- United States
- Volunteers
- 1,163 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Obesity, Insulin Resistance
A Trial to Study the Effect of Long Term Vitamin D Supplementation on Insulin Sensitivity
Type 2 diabetes is a major public health problem in India with an estimated a prevalence of approximately 4% and 12% in rural and urban areas respectively.
- Trial name
- LongtermVitD (NCT01052181)
- Testing
- Cholecalciferol
- Where
- India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Dr Jitender Nagpal
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