Clinical trials: Healthy Control Group
Psoriasis
A Clinical Study of ICP-488 in Healthy Subjects and Patients With Psoriasis
This is a Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Single and Multiple AscendingDose Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ICP-488 in Healthy Subjects…
- Trial name
- NCT05451199
- Testing
- ICP-488
- Where
- 7 sites in China
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Beijing InnoCare Pharma Tech Co., Ltd.
Macular Degeneration
A Safety Study to Evaluate Pazopanib Eye Drops in Healthy Volunteers
A study to determine the safety and tolerability of pazopanib eye drops. The study will also determine how the drug is absorbed and metabolized over time.
- Trial name
- NCT01072214
- Testing
- pazopanib
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Volunteer Study
Exploratory Clinical Study to Assess Safety and Efficacy of Xenon Gas Inhalation to Control Neuroinflammation
The goal of this clinical study is to evaluate safety of Xenon gas inhalation in healthy volunteers. This first phase safety clinical study is part of evaluation of the xenon gas inhalation as a therapy for neurodegenerative…
- Trial name
- NCT06945614
- Testing
- Xenon gas inhalation
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- General Biophysics LLC
Glycemic Control, Diabetes Mellitus Risk
Effects of Seaweed Extract on Postprandial Response to White Bread
The study is designed to determine whether seaweed extract added to a carbohydrate-rich meal, can lower blood glucose levels after its consumption, and hence lower its glycaemic index, and if this effect is mediated through…
- Conditions
- Glycemic Control, Diabetes Mellitus Risk, Glucose Intolerance, Postprandial Hyperglycemia
- Trial name
- NCT05460884
- Testing
- Seaweed extract LD and white bread, Seaweed extract HD and white bread, White bread
- Where
- Ireland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Varicella Zoster, Immunization; Infection
Safety Study of NBP608 in Healthy Adult Volunteers
Indication: Protection against varicella and herpes zoster Study Objectives Primary: Safety and tolerability assessment after single dose administration of NBP608 Secondary: immunogenicity assessment after single dose…
- Trial name
- NCT03121638
- Testing
- VARIVAX, ZOSTAVAX, NBP6081
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- SK Chemicals Co., Ltd.
Healthy
Functional Differences in Effortful Control
The purpose of this study was to learn more about the brain circuits involved with effortful control in healthy adult participants.
- Trial name
- FDEC (NCT01993147)
- Testing
- Dual task paradigm pilot
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Healthy Participants
Cannabinoid Control of Fear Extinction Neural Circuits in Humans
The goal of the current proposal is to investigate the effects of a cannabinoid drug on the memory of extinguished fear in humans and the brain circuitry important for the recall of extinction learning.
- Trial name
- NCT02472847
- Testing
- Dronabinol
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Healthy Volunteer
A 2-Part Study to Evaluate the Safety of Supra-Therapeutic Doses of RO4602522 and to Investigate the Effect of RO4602522 on the QTc Interval
This is a 2 part study to evaluate the safety and tolerability of supra-therapeutic doses of RO4602522 (Part A); and to investigate the effect of RO4602522 on the QTcF interval in healthy volunteers (Part B).
- Trial name
- NCT02104648
- Testing
- RO4602522, moxifloxacin
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Stress, Psychological, Social Isolation
Stay Healthy In Nature Everyday: Family Nature Outings in a Low Income Population
The SHINE study is a randomized controlled study of the effect of a park-based family support group on multiple outcomes (including stress and physical activity) in a low income population.
- Conditions
- Stress, Psychological, Social Isolation, Physical Activity
- Trial name
- SHINE (NCT02623855)
- Testing
- Family outings, Park prescription, Pedometry
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Healthy
Neural Adaptations to a Single Session of Metronome-Paced Strength Training
The aim of the study is to investigate the effects of incorporating variability within a single session of Resistance Training (RT) methods on the neural adaptations along the corticospinal tract and on neuromuscular function.
- Trial name
- NCT06539650
- Testing
- Fractal Paced, Isochronus Paced, Self Paced
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Pain Relief
Daily Sessions of rTMS to the Left DLPFC Modulate the Pain Thresholds and CPM
The main purpose of the study is to assess whether repeated sessions of repetitive trancranial magnetic stimulation (rTMS) applied on left dorsolateral prefrontal cortex main boost the pain thresholds.
- Trial name
- NCT03733015
- Testing
- repetitive transcranial magnetic stimulation
- Where
- 2 sites in Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Tropical Spastic Paraparesis
MRI Brain Studies in Patients With HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis
This study will use three different magnetic resonance imaging (MRI) techniques to study HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/STP)-a disease of slowly progressive weakness in the legs.
- Trial name
- NCT00034723
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Atopic Dermatitis
Safety, Tolerability, Pharmacokinetics and Efficacy of Twice Daily Application of Topical BioLexa in Adult Healthy Subjects and Patients With Mild to Moderate Atopic Dermatitis
This is a Phase 1, randomised, double-blind, vehicle controlled study to determine the safety, tolerability, PK and efficacy of twice daily application of topical BioLexa™ lotion, administered for 28 days in adult healthy…
- Trial name
- NCT04544943
- Testing
- BioLexa- Cohort 1, BioLexa- Cohort 2, Gentamicin
- Where
- Australia
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Hoth Therapeutics, Inc.
Renal Failure, Chronic, End-Stage Renal Disease
PK of Serelaxin in Severe Renal Impairment and ESRD
The study is designed to evaluate the pharmacokinetics, safety and tolerability, immunogenicity and pharmacogenetics of a single dose of serelaxin/RLX030 in patients with severe renal impairment and end-stage-renal-disease (ESRD)…
- Trial name
- CRLX030A2102 (NCT01875523)
- Testing
- Serelaxin
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Healthy Males
ITT4 Intratesticular Hormonal Milieu in Man (ITT4)
The purpose of this research study is to determine how much male hormone, testosterone, is necessary to maintain sperm production in the testis.
- Trial name
- ITT4 (NCT01215292)
- Testing
- Acyline, Testosterone gel, ketoconazole 400
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Washington
Healthy
To Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 1467335 Following Multiple Dose Administration Over 28 Days
The primary objective of this trial is to investigate the safety and tolerability of BI 1467335 in healthy male and female subjects following oral administration of multiple rising doses over 28 days.
- Trial name
- NCT02733627
- Testing
- BI 1467335
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
The Glycaemic Index of Manuka Honey
Five high methylglyoxal (460-667 mg/kg) Manuka honey samples were selected from different geographical locales around the North Island of New Zealand and tested for glycaemic index (GI) in 10 healthy volunteers in a…
- Trial name
- NCT01615588
- Testing
- Manuka Honey
- Where
- New Zealand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Waiariki Institute of Technology
Complex Regional Pain Syndromes, Healthy
Study of Proteins Associated With Complex Regional Pain Syndrome
This study will try to learn more about complex regional pain syndrome, or CRPS (previously known as reflex sympathetic dystrophy, spreading neuralgia, and sympathalgia), by examining the release of small proteins in the blood of…
- Trial name
- NCT00033969
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Parental Feeding Practices and Children's Healthy Diet
The SmartFeeding4Kids: Study of a New Web-based Food Parenting Intervention
This research aims to develop and study the efficacy of a web-based brief intervention, Smart Feeding4Kids, to promote healthy dietary patterns in young children (2 to 6 years old) through changes in parents' feeding practices.
- Trial name
- SF4K (NCT04591496)
- Testing
- Behavioral change intervention;, Health Education
- Where
- Portugal
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Leukemia
Molecular Epidemiology of Acute Myelogenous Leukemia
Little is known about the epidemiologic risk factors associated with the development of acute myelogenous leukemia (AML), and less is known about the role that genetic susceptibility plays in the development of AML.
- Trial name
- NCT00502983
- Testing
- Interview
- Where
- United States
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
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