Clinical trials: Healthy Control Group
Healthy Women, Female Contraception
Study of Efficacy, Cycle Control, and Safety of a NES-E2 Contraceptive Vaginal Ring
This will be a multi-site, open-label, randomized clinical trial. The investigators will randomize 300 eligible participants in a 1:1 ratio to two different treatment regimens that are to be followed when using a contraceptive…
- Trial name
- NCT03432416
- Testing
- NES-E2 CVR
- Where
- 11 sites in United States
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Premier Research
Intervention, Wait-List Control
Ignite Study of the Jewish Family and Children's Service of the Suncoast, Inc.
The goals of the program are to help struggling fathers and father figures improve the parent-child relationship, sustain healthy marriages and relationships (and help those who are single identify ways to enter into safe and…
- Trial name
- Ignite (NCT05356234)
- Testing
- Treatment Intervention: Responsible Parenting, Relationships, and Employment Services
- Where
- United States
- Volunteers
- 675 people, healthy volunteers welcome
- Sponsor
- Jewish Family & Children's Service of the Suncoast, Inc.
Healthy, Athletic Performance
Weighted-Vest Versus Bodyweight Plyometric Training in Youth Female Soccer Players
Lower extremity strength, explosive power, dynamic balance and functional movement quality are important determinants of performance and injury prevention in soccer.
- Trial name
- NCT07705087
- Testing
- Body-Weight Plyometrics, Additional Loaded Plyometric, Routine Football Training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Healthy
A Study in Japanese Healthy Men to Test How Well Different Doses of BI 3031185 Are Tolerated and a Study in Japanese Healthy Women to Test Whether BI 3031185 Influences the Amount of a Contraceptive in the Blood
Single dose (SD) part: The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 3031185 in healthy male trial participants following oral administration of single dose.
- Trial name
- NCT07656792
- Testing
- BI 3031185, Midazolam, YAZ®
- Where
- Japan
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Study to Evaluate Efficacy and Safety of IW-6118 in Patients Undergoing Third Molar Extraction
The purpose of this study is to assess the safety of IW-6118 when administered as a single oral dose to patients undergoing third molar extraction. Efficacy will be assessed in an exploratory manner.
- Trial name
- NCT01107236
- Testing
- IW-6118, Naproxen Sodium
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ironwood Pharmaceuticals, Inc.
Chronic Kidney Disease, Healthy Volunteers
A Study to Learn How Safe the Study Treatment BAY3283142 is, How it Affects the Body, How it Moves Into, Through and Out of the Body When Single and Multiple Amounts Are Taken as Tablets in Japanese Healthy Male Participants
Researchers are looking for a better way to treat people who have chronic kidney disease (CKD). The kidneys filter extra water and waste out of the blood and make urine.
- Trial name
- NCT05800444
- Testing
- BAY3283142
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy, Hypercapnia
Role of Prostaglandins in the Regulation of Brain Blood Flow
This study will use magnetic resonance imaging (MRI) to examine the role of prostaglandins-a type of fatty acid with hormone-like actions-in the regulation of brain blood flow.
- Trial name
- NCT00006318
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Ataxia, Cerebrovascular Accident
PET Scan to Study Brain Control of Human Movement
Positron Emission Tomography (PET) is a technique used to investigate activity in areas of the brain. The PET technique allows researchers to study the normal processes in the brain (central nervous system) of normal individuals…
- Conditions
- Ataxia, Cerebrovascular Accident, Healthy, Movement Disorder
- Trial name
- NCT00001324
- Where
- United States
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy Participants
Single Dose, Three-arm Study to Compare the Pharmacokinetic Similarity of MAB-22 Versus Prolia®
A Randomized, Double-blind, Controlled, Parallel-group, Single Dose, Three-arm Study to Compare the Pharmacokinetic Similarity of MAB-22 Versus Prolia®
- Trial name
- NCT06310824
- Testing
- MAB-22, EU-Prolia®, US-Prolia®
- Where
- 2 sites in Hungary, Netherlands
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Xentria, Inc.
Diabetes, Diabetes Mellitus, Type 2
A Trial to Assess the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Oral Semaglutide in Healthy Male Japanese and Caucasian Subjects
This trial is conducted in Asia. The aim of the trial is to investigate the pharmacokinetics (the exposure of the trial drug in the body), pharmacodynamics (the effect of the investigated drug on the body), safety and…
- Conditions
- Diabetes, Diabetes Mellitus, Type 2, Healthy
- Trial name
- NCT02161588
- Testing
- semaglutide
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Skin Disease, Immune System Disease
A Study of HL40626S Tablets in Healthy Adults
This is a single-centre, randomized, double-blind, placebo-controlled Phase 1 study to assess safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity of HL40626S tablets following single and…
- Conditions
- Skin Disease, Immune System Disease, Skin Diseases, Papulosquamous, Psoriasis (PsO)
- Trial name
- NCT07736586
- Testing
- HL40626S tablets
- Where
- 2 sites in Australia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- HighsLab Therapeutics Inc.
Healthy
Study to Investigate Safety and Tolerability of BI 1744 CL in Free Dose Combination With Tiotropium Bromide Both Administered by Respimat® in Healthy Male Volunteers
Study to investigate safety and tolerability of single, inhaled doses (2.5 μg, 5 μg, 10 μg, 20 μg and 40 μg) of BI 1744 CL in free dose combination with tiotropium bromide 5 μg (for doses up to and including 20 μg BI 1744 CL) and…
- Trial name
- NCT02259946
- Testing
- BI 1744 CL, Tiotropium bromide
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Safety and Tolerability of BI 638683 After Single Rising Oral Doses in Healthy Male Subjects
The primary objective of the current study is to investigate the safety and tolerability of BI 638683 in healthy male volunteers following oral administration of single rising doses
- Trial name
- NCT01195688
- Where
- Germany
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Volunteers (Meningococcal Infection)
Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US
The purpose of this study was to compare the immunogenicity and describe the safety of MenACYW conjugate vaccine and MENVEO® when both are administered concomitantly with routine pediatric vaccines to healthy infants and toddlers…
- Trial name
- NCT03537508
- Testing
- MenACYW conjugate vaccine, MenACYW-135 conjugate vaccine, DTaP-IPV//Hib vaccine
- Where
- 70 sites in United States, Puerto Rico
- Volunteers
- 2,627 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Clinical Trials, Phase I as Topic
First in Human Study in Healthy Volunteers to Investigate the Safety, Tolerability and Pharmacokinetics of BAY1214784
This study is a first in human study that will investigate the safety, tolerability and pharmacokinetics of ascending single doses of BAY1214784 using a placebo controlled, randomized, single center design.
- Trial name
- NCT02212080
- Testing
- BAY1214784
- Where
- 2 sites in Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
A Study in Healthy Volunteers to Assess Safety and Blood Levels of AZD9742 After Multiple Doses Over 14 Days
The purpose of this study is to determine the safety, tolerability and blood levels of AZD9742 after daily dosing for 14 days.
- Trial name
- NCT01064388
- Testing
- AZD9742
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Atopic Dermatitis
Study to Evaluate Safety and Tolerability of PF-07242813 in Healthy Participants and Participants With Atopic Dermatitis
This is the first time PF-07242813 will be given to humans. The purpose of the study is to evaluate the safety, tolerability, and pharmacokinetics of escalating single and repeat doses of PF-07242813 in healthy participants and…
- Trial name
- NCT04668066
- Testing
- PF-07242813
- Where
- 7 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
Quality Control of Cardiopulmonary Exercise Equipment
This study is designed to make sure exercise equipment used by the National Heart, Lung, and Blood Institute is working properly.
- Trial name
- NCT00001883
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Healthy
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HS-20004 in Healthy Chinese Volunteers
This trial is conducted in China. The aim of this trial is to assess the safety and tolerability of HS-20004 in healthy Chinese subjects.
- Trial name
- NCT02746302
- Testing
- HS-20004
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Healthy Volunteers
The Operation of Control Devices During Parabolic Flights: Influence of Weightlessness, Stress and Motivation
The aim of this project is to investigate whether alterations in sensory-motor performances during weightlessness are only of theoretical relevance, or indeed restrict the capacity of the participants.
- Trial name
- Grafism (NCT02563275)
- Testing
- motion analysis system, parabolic flight
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
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