Clinical trials: Healthy Control Group
Healthy, Blood Glucose
A Clinical Trial to Investigate the Efficacy of Bragg Apple Cider Vinegar on Blood Glucose Control in a Healthy Adult Population
The goal of this clinical study is to investigate the efficacy of a Bragg Apple Cider Vinegar (ACV) liquid on postprandial glucose (PPG) excursion compared to a placebo following a standardized acute carbohydrate load.
- Trial name
- NCT07043478
- Testing
- Bragg ACV Liquid
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bragg Live Food Products
Healthy
Pilot Study: Effects of G-CSF on T Cell Function
This study will evaluate changes in T cells-infection-fighting white blood cells of the immune system-in people given a drug called G-CSF before donating stem cells (immature bone marrow cells) for transplantation.
- Trial name
- NCT00039650
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy
Multiple Dose Study To Investigate The Effects Of Fesoterodine And Solifenacin On Gastrointestinal Transit
To assess the effect of fesoterodine 8 mg as compared to solifenacin 10 mg on colonic transit.
- Trial name
- NCT00832650
- Testing
- fesoterodine fumarate, solifenacin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pfizer
Sickle Cell
Stem Cell Collection for Adult Volunteers
This study will examine the development of stem cells (very immature cells produced by the bone marrow) and their potential to change into cells of other organ types.
- Trial name
- NCT00033774
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Healthy Subjects
Study to Evaluate Safety and Tolerability of ACT-709478 in Healthy Subjects
The primary purpose of this study is to evaluate the safety and tolerability of ascending multiple doses of ACT-709478 in healthy male and female subjects
- Trial name
- NCT03165097
- Testing
- ACT-709478, Midazolam, ACT-709478 combined with midazolam
- Where
- Germany
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Healthy
Assess Safety, Tolerability and PK of AZD3199 in Japanese
The primary objective of the study is to investigate the safety and tolerability of single and multiple once daily ascending doses of AZD3199 delivered as dry powder via the Turbuhaler inhaler in healthy male Japanese subjects by…
- Trial name
- NCT00772759
- Testing
- AZD3199 Turbuhaler®
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Typhoid
Non-inferiority Trial of Locally Manufactured Typhoid Conjugate Vaccine 'Typhocon' in Bangladesh
This is a double blinded, randomized-controlled, non-inferiority trial of a typhoid conjugate vaccine, Typhocon (Vi- polysaccharide conjugated to diphtheria toxoid, Vi-DT), manufactured by a local company, Incepta Vaccine…
- Trial name
- NCT05475379
- Testing
- Typhoid Vi polysaccharide-diphtheria toxoid conjugate vaccine (Vi-DT)
- Where
- Bangladesh
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Healthy Volunteers, Non Diabetic Hyperglycemia
Safety of Mulberry Leaf Extract Capsule on Blood Glucose Control in Healthy Volunteer
Volunteers were divided into 2 groups: mulberry leaf extract capsule (DNJ 12mg) group and placebo group. They took the sample 3 times/day for 8 weeks.
- Trial name
- NCT07532135
- Testing
- Mulberry Leaf Extract
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Hepatic Impairment, Liver Disease
Elafibranor Pharmacokinetic Parameters in Hepatic Impaired Patients
This study is being conducted in order to assess the need for dose adjustment for elafibranor in patients with hepatic impairment.
- Conditions
- Hepatic Impairment, Liver Disease, Pharmacokinetics
- Trial name
- NCT03765671
- Testing
- Elafibranor
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Genfit
Invasive Group B Streptococcus (GBS) Disease
A Phase I, Randomized, Single-blind, Controlled, Single Center Study to Evaluate the Safety and Immunogenicity of a Dose Range of a Monovalent Glycoconjugate Antigen Vaccine of Group B Streptococcus in Healthy Women 18-40 Years of Age
The goals of the proposed study are to evaluate the safety, tolerability and immunogenicity of a GBS vaccine. Previous studies suggest that immune responses against GBS can protect humans from infection.
- Trial name
- NCT00657683
- Testing
- Monovalent GBS-CRM glycoconjugate vaccine
- Where
- Switzerland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Elevated S-adenosylhomocysteine
Role of a Dietary Supplement in Lowering SAH in Healthy Adults With Elevated Plasma SAH and Normal Homocysteine Levels
S-adenosylhomocysteine (SAH) is the end-product of methylation reactions in the body and the precursor to homocysteine. Elevated SAH in the blood is a reflection of the dysregulation of what is known as the S-adenosylmethionine…
- Trial name
- SAH (NCT05994794)
- Testing
- Alpha-GPC, Creatine and Ashwagandha (Sensoril®)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Standard Process Inc.
Healthy
Exploratory Study to Assess the Pharmacokinetics of AZD5985
The aim of this exploratory study is to assess the pharmacokinetics of increasing oral doses of AZD5985 in healthy male volunteers
- Trial name
- NCT00799331
- Testing
- AZD5985
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Idiopathic Pulmonary Fibrosis (IPF)
Biomarker Discovery for Novel Drug Development in Idiopathic Pulmonary Fibrosis
Drug discovery can take many years especially since most studies to measure effectiveness depend on clinical outcomes like pulmonary function tests and hospitalizations.
- Trial name
- NCT01718990
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
Phase I Study of PSD502 (Lidocaine Prilocaine Spray) Applied to the Glans Penis up to Three Times a Day for 21 Days in Healthy Male Volunteers
The main objective of the study is to determine the safety and tolerability of repeated application of PSD502 to the glans penis in healthy male volunteers
- Trial name
- NCT00483990
- Testing
- PSD502
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Plethora Solutions Ltd
Healthy
Assessment of the Effect of BI 201335 on the QT Interval in Healthy Female and Male Subjects
To demonstrate that BI 201335 does not prolong the QT interval more than placebo. To assess the tolerability of 1200 mg of BI 201335 as single dose in female subjects (double-blind, randomised, placebo-controlled) before…
- Trial name
- NCT02182310
- Testing
- BI 201335 low dose, Moxifloxacin, BI 201335 high dose
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Type 1 Diabetes Mellitus (T1DM), Healthy Control
Environmental Determinants of Type 1 Diabetes Risk
To analyze the environmental risk factors for type 1 diabetes in China.
- Conditions
- Type 1 Diabetes Mellitus (T1DM), Healthy Control, Relatives to/Carers of Patients
- Trial name
- NCT07835724
- Where
- China
- Volunteers
- 11,240 people, healthy volunteers welcome
- Sponsor
- Second Xiangya Hospital of Central South University
Depression, Depression, Bipolar
Dallas 2K: A Natural History Study of Depression
The primary objective of this initiative is to implement a prospective study that will allow us to identify and validate biosignatures of response to treatments for depression and depression outcome (using an integrated array of…
- Trial name
- D2K (NCT02919280)
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Infection by Streptococcus Group B
Safety and Immunogenicity of a Group B Streptococcus Vaccine in Non-pregnant Women 18-40 Years of Age.
Part A: The primary objective is to evaluate the safety and tolerability of a potential vaccine against Group B streptococcus. Part B: To evaluate the long term safety profile of the GBS-NN vaccine up to one year following the…
- Trial name
- MVX13211 (NCT02459262)
- Testing
- GBS-NN vaccine
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Minervax ApS
Diabetes Mellitus, Type 2
Albiglutide Thorough ECG Study in Healthy Volunteers
This study is designed to investigate the effect of treatment with albiglutide on the cardiac repolarization (corrected QT interval) in healthy male and female subjects.
- Trial name
- NCT01406262
- Testing
- Albiglutide, Moxifloxacin
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Clinical Trials, Phase I as Topic
First in Human Study in Healthy Volunteers to Investigate the Safety, Tolerability and Pharmacokinetics of BAY1214784
This study is a first in human study that will investigate the safety, tolerability and pharmacokinetics of ascending single doses of BAY1214784 using a placebo controlled, randomized, single center design.
- Trial name
- NCT02212080
- Testing
- BAY1214784
- Where
- 2 sites in Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bayer
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