Clinical trials: Healthy Control Group
Group A Streptococcal Infection
A Trial of a Peptide-based Group A Streptococcal (GAS) Vaccine Candidate in Healthy Individuals.
The purpose of this study is to investigate the safety and antibody (germ fighters) response of experimental (investigational) vaccine candidates against the germ group A streptococcus when injected into the arm of healthy adults.
- Trial name
- NCT04882514
- Testing
- p*17-K4S2, J8-K4S2, Rabavert vaccine
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Suicide and Depression
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
Despite increasing suicide rates in adolescents, there remains a paucity of approaches to use to prevent re-attempts. Any hope for breaking the code to prevent youth suicide lies in understanding biological factors that play a…
- Trial name
- NCT04783506
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Healthy
Safety, Tolerability and Pharmacokinetics of BI 653048 H3PO4 Oral Drinking Solution in Healthy Male Volunteers
Investigation of safety and tolerability of BI 653048 H3PO4 following the administration of single rising doses of an aqueous solution in healthy male subjects Pharmacokinetic and pharmacodynamic characteristics of BI 653048…
- Trial name
- NCT02217644
- Testing
- BI 653048 H3PO4 solution, BI 653048 H3PO4 low dose capsule, BI 653048 H3PO4 high dose capsule
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study of the Effects of a One-session Mindfulness of the Breath Meditation Practice on State Hope and State Gratitude in the General Population
This study aims to examine whether a brief mindfulness of the breath meditation practice is more helpful than listening to an audio recording in relation to improving hope and gratitude in the general population.
- Trial name
- NCT04099758
- Testing
- Mindfulness of the breath meditation, Audio-recording control
- Where
- United Kingdom
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Breast Cancer, Shoulder
Morbidity After Diagnosis and Treatment of Breast Cancer Patients
This study will examine the frequency and severity of problems in women with breast cancer for 2 years following initial medical treatment, including: Physical impairments, such as loss of strength or flexibility, increased…
- Conditions
- Breast Cancer, Shoulder, Lymphedema, Fatigue
- Trial name
- NCT00027118
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy
A Multiple Ascending Dose Study of KBP-7072 in Healthy Subjects
This is a randomized, single-blind, placebo-controlled, sequential parallel-group and multiple ascending dose (MAD) study to evaluate the safety, tolerability and pharmacokinetics of KBP 7072 in healthy subjects.
- Trial name
- NCT02654626
- Testing
- KBP-7072
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- KBP Biosciences
Pneumococcal Infections
Study of the Safety and Immunogenicity of Catch-up Vaccination With a 21-valent Pneumococcal Conjugate Vaccine (PCV21) in Healthy Infants, Toddlers, Children, and Adolescents
The purpose of this study is to evaluate the safety and immunogenicity of PCV21 versus 20vPCV ( 20-valent pneumococcal conjugate vaccine, Prevnar 20) for catch-up vaccination in infants (7 to 11 MoA-Months of age), toddlers (12…
- Trial name
- NCT06838000
- Testing
- PCV21, 20vPCV
- Where
- 38 sites in United States, Estonia and 2 more
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Viral Infection
Study to Determine the Safety, Tolerability and Pharmacokinetics of UV-4B Solution Administered Orally in Healthy Subjects
The objective is to evaluate the safety and tolerability of a single-ascending oral dose of UV-4B in healthy subjects and to determine pharmacokinetic parameters describing absorption and elimination following a single dose of…
- Trial name
- UV (NCT02061358)
- Testing
- UV-4B 3 mg, UV-4B 10 mg, UV-4B 30 mg
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Emergent BioSolutions
Healthy
Healthy Human Control Blood Collection for Validation of Biomarker Assay
Human blood will be collected to serve as control in validating clinical studies studying the detection and levels of circulating tumor cells and microvesicles in cancer patients.
- Trial name
- NCT02302885
- Testing
- Blood collection
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Immune Mediated Inflammatory Diseases
A Trial to Learn How BAY1834845 and BAY1830839 Affect Inflammation When Taken by Mouth Twice a Day for 7 Days in a Row in Healthy Male Participants
The immune system helps protect the body from diseases. But, sometimes the immune system can be too sensitive and overreact to very small allergens, like dust and pet dander.
- Trial name
- NCT05003089
- Testing
- BAY1834845, BAY1830839, Prednisolone
- Where
- Netherlands
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Bayer
Reflux Oesophagitis
Effect of 5, 10 or 25 mg of YF476 Daily for 14 Days on Stomach Acidity in Healthy Volunteers
The objective of the study was to assess whether the tolerance to the effect of YF476 on gastric pH observed with repeated doses in a previous study in healthy volunteers can be avoided by using smaller doses of YF476.
- Trial name
- NCT01597674
- Testing
- YF476
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Trio Medicines Ltd.
Herpes Zoster, Herpes Zoster Vaccine
Clinical Trial of Recombinant Herpes Zoster Vaccine (CHO Cell) in Healthy Chinese Population Aged 40 Years and Older
The objective of this study was to evaluate the safety, immunogenicity and immune persistence of recombinant herpes zoster vaccine (CHO cells) with different adjuvant doses in healthy people aged 40 years and older.
- Trial name
- NCT06851832
- Testing
- Recombinant zoster vaccine(CHO cell)(low adjuvant), Recombinant Zoster Vaccine (CHO cell), Zoster Vaccine, Live
- Where
- China
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Ab&B Bio-tech Co., Ltd.JS
Healthy
Single Rising Peroral Doses of BI 1744 CL in Healthy Volunteers
Study to investigate safety, tolerability, and pharmacokinetics of single rising peroral doses of BI 1744 CL.
- Trial name
- NCT02171793
- Testing
- BI 1744 CL
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Psychosis; Schizophrenia-Like, Healthy Controls
Mechanisms of Response to Therapeutic Intervention in Clinical High Risk (CHR) for Psychosis
This study, "Psychobiological Follow-up Study of Transition from Prodrome to Early Psychosis", will be conducted in collaboration with the Shanghai Mental Health Center (SMHC) and several data processing sites in the United…
- Trial name
- NCT06542640
- Testing
- Mb-rt-fMRI-NFB, rTMS
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Healthy
Study to Assess Safety, Tolerability and Pharmacokinetics After Single Doses of AZD1446 to Healthy Volunteers
The primary purpose of this study is to assess the safety and tolerability of AZD1446 following single dose administration.
- Trial name
- SAD (NCT00803855)
- Testing
- AZD1446
- Where
- Sweden
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Autophagy
Expression of LC3-I, LC3-II & Beclin 1 in Vitiligo
The exact mechanism of impairment of autophagy in vitiligo has not yet been determined.
- Trial name
- NCT03371758
- Testing
- skin biopsy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes, Diabetes Mellitus, Type 2
Effect of Liraglutide on Heart Frequency in Healthy Volunteers
This trial is conducted in the United States of America (USA). The aim of this trial is to investigate if liraglutide effects the QTc interval. Moxifloxacin (Avelox®) is administered as positive control.
- Trial name
- NCT01516255
- Testing
- liraglutide, moxifloxacin, electrocardiogram (ECG)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Healthy Volunteers
The Effects of Intragastric Administration of Nutrients on Executive Control in Healthy Subjects.
The previous research by one of our members in the research team (H. Miller) suggests a possible influence of oral nutrients intake of certain fat or carbohydrates (glucose, fructose) on executive control.
- Trial name
- NCT02800538
- Testing
- intragastric infusion of nutrient
- Where
- Belgium
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Physical Activity
Healthy Activities Improve Lives (HAIL)
The investigators have developed an online platform to support the 8-week, F\&S! exercise program called the Healthy Activity Improves Lives (HAIL) online platform.
- Trial name
- HAIL (NCT06267547)
- Testing
- HAIL Online Platform, Fit and Strong! Program
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy Participants
Cannabinoid Control of Fear Extinction Neural Circuits in Humans
The goal of the current proposal is to investigate the effects of a cannabinoid drug on the memory of extinguished fear in humans and the brain circuitry important for the recall of extinction learning.
- Trial name
- NCT02472847
- Testing
- Dronabinol
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
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