Clinical trials: Healthy Individual
Hypertension
To Compare the Pharmacokinetics of Fimasartan/Amlodipine Combination Tablet and Coadministration of Fimasartan and Amlodipine as Individual Tablets
An Open-label, Randomized, Single-dose, 2×2 Crossover Study to Compare the Pharmacokinetics of Fimasartan/Amlodipine Combination Tablet and Coadministration of Fimasartan and Amlodipine as Individual Tablets in Healthy Male…
- Trial name
- NCT02205151
- Testing
- Fimasartan, Amlodipine, Fimasartan/Amlodipine combination
- Where
- South Korea
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Healthy
Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of BI 113823 Powder in Bottle (PiB) and Tablet in Healthy Male Volunteers
To investigate the safety, tolerability, and pharmacokinetics incl. dose proportionality of BI 113823, as well as the relative bioavailability of PiB vs. tablet and tablet fasted vs. fed (food effect for the tablet).
- Trial name
- NCT02259972
- Testing
- BI 113823 solution, BI 113823 tablet, High fat, high calorie breakfast
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Pharmacokinetics, Healthy Volunteers
A Study to Learn About the Study Medicine Called Nirmatrelvir/Ritonavir in People Who Are Healthy Volunteers Co-administered the Medicine Rosuvastatin
The purpose of this study is to learn about the effect of the study medicine (called nirmatrelvir/ritonavir) on the pharmacokinetics of the medicine rosuvastatin in healthy volunteers.
- Trial name
- NCT05898672
- Testing
- Rosuvastatin, Nirmatrelvir/ritonavir
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Constipation
Efficacy Evaluation of Probiotic Product on Bowel Habits in Healthy Subjects
The objective of this study is to evaluate if consumption of fermented milk containing Lactobacillus casei strain Shirota has an impact on stool consistency, stool frequency, constipation-related symptoms, and quality of life in…
- Trial name
- NCT01375712
- Testing
- Fermented milk containing Lactobacillus casei strain Shirota
- Where
- Germany
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Yakult Honsha Co., LTD
Healthy Cohort
The NICOLA Questionnaire Trial (NICOLA-QT)
Recruiting, retaining and gathering complete data on participants in research projects, be they patients or health professionals, can be extremely difficult.
- Trial name
- NCT01978522
- Testing
- Randomisation of questionnaire receipt.
- Where
- United Kingdom
- Volunteers
- 8,500 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Varicella
A Trial to Evaluate the Lot-to-lot Consistency of Live Attenuated Varicella Vaccine in Healthy People 1-12 Years of Age
The goal of this clinical trial is to evaluate the lot-to-lot consistency, immunogenicity, and safety of live attenuated varicella vaccine manufactured by Beijing Institute of Biological Products Co., Ltd in healthy children.
- Trial name
- NCT05839301
- Testing
- Investigational live attenuated varicella vaccine (lot 1), Investigational live attenuated varicella vaccine (lot 2), Investigational live attenuated varicella vaccine (lot 3)
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- China National Biotec Group Company Limited
Healthy, Chronic Kidney Disease
A Study in People With Normal Kidney Function and People With Reduced Kidney Function to Test How BI 764198 is Processed in the Body
The main objective of this trial is to investigate the influence of moderate and severe renal impairment on the pharmacokinetics of a single dose of BI 764198 in comparison to a group of matched controls with normal renal…
- Trial name
- NCT04176536
- Testing
- BI 764198
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Effects of Dietary Interventions on the Aging Brain
The researchers will investigate whether caloric restriction or dietary supplementation could provide positive effects on general brain functions in healthy elderly people.
- Trial name
- NCT00996229
- Testing
- Caloric restriction, Omega-3 (fish oil capsules), Resveratrol
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Healthy
Safety, Pharmacokinetics, and Pharmacodynamics of BIRT 2584 XX Administered as Multiple Doses and Safety and Pharmacokinetics of BIRT 2584 XX Administered With and Without Food as Single Dose to Healthy Male Volunteers
The study comprised two parts. The objective of the first study period was to assess the safety and pharmacokinetics of 500 mg of BIRT 2584 XX tablets administered with and without food in male healthy volunteers and to determine…
- Trial name
- NCT02256761
- Testing
- BIRT 2584 XX - multiple escalating dose, BIRT 2584 XX - single dose, high caloric meal
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Sleep Deprivation
Protective Effect of Statin on Sleep Deprivation
This study aimed to investigate the effect of 48-h sleep deprivation on heart rate variability (HRV) in young healthy people and the protective effect of statin on arrhythmia and HRV.
- Trial name
- NCT02496962
- Testing
- Atorvastatin
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shi Yang
Condition: Healthy
Resting-state Connectivity and Individual Differences in Affective Placebo Responsiveness
Expectation effects on affective states are central to mechanisms relevant for mood disorders and their treatment. This study will test whether inter-individual differences in resting-state functional connectivity (rsFC) within…
- Trial name
- NCT07479966
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stefanie Brassen
Healthy People Programs
SNIF (Sniff Nasal Inspiratory Force) Reference Values Of Mediterranean Population
SNIF test has been described as a method to explore the diaphragmatic function. But there are no defined the reference values of this test in healthy population.
- Trial name
- SNIF REF V (NCT01886339)
- Testing
- SNIF test (Sniff Nasal Inspiratory Force)
- Where
- Spain
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Mild Cognitive Impairment (MCI), Mild Alzheimer Disease
A Study To Assess The Feasibility Of Indivi Mobile Application In Monitoring Cognitive Performance In Aging Population
The goal of this observational study is to evaluate the functionality and usability of Indivi mobile application-based cognitive activities in people with mild cognitive impairment/mild Alzheimer's disease (PwMCI/AD) and healthy…
- Trial name
- ADAPT-MCI-01 (NCT07174869)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Indivi AG
Major Depressive Disorder (MDD)
Reward-specific Changes of the Chemical Messenger Dopamine in the Brain of Healthy and Depressed People
Major depressive disorder was shown to be associated with pathological alterations within neurotransmitter systems of the brain.
- Trial name
- NCT06675851
- Testing
- WELLBUTRIN SR (Bupropion HCI) Sustained-Release Tablets, 150 mg; GlaxoSmithKline, Cipralex (escitalopram)
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Falls Prevention
Vibration Training for Preventing Falls in Healthy Population and Multiple Sclerosis
This study is to investigate the effects of controlled whole-body vibration training on reducing the likelihood of falls among healthy population and people with multiple sclerosis.
- Trial name
- NCT02694666
- Testing
- Controlled whole-body vibration training
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Schizophrenia
The Effect of Intranasal Administration of Oxytocin on Empathic Abilities.
Empathy constitutes one prominent ability of social cognition, which represents the human capability of understanding mental state of the other, and responding in sympathetic way.
- Trial name
- 20070766 (NCT00813436)
- Testing
- Oxytocin (also: syntocinon, pitocin)
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Healthy
Metabolic and Physiological Stress During Skiing.
Problem description In industrialized countries there is a rapid increase in the number of senior citizens. In Austria more than 50% of the population is overweight, with highest prevalence in the age group from 60 to 74 yrs and…
- Trial name
- NCT02082106
- Testing
- Alpine skiing, cross country skiing, Indoor training (cycling)
- Where
- Austria
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University
Vascular Complications, Diabetic
Effects of Flavanoids in Essential Hypertension, Type 2 Diabetes and Healthy Persons
Flavanols are natural substances who are frequently found in our nutrition. A lot of research has already been executed in the past to investigate what effects this flavanols could have in the human population.
- Trial name
- NCT03722199
- Testing
- flavanols (subgroup of polyphenols, subgroup of phenolics, natural substances)
- Where
- Belgium
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University Ghent
PAIN
A First In Human Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Single Oral Doses Of PF-06273340
The purpose of this study in healthy people is to evaluate safety, toleration and time course of plasma concentration of single oral doses of PF-06273340.
- Trial name
- NCT01601834
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
Clinical Effect of Two Pharmacokinetics Model of Propofol
Actually, Schnider and Cortinez models represent pharmacokinetics models of propofol more complete published until now. Schnider was derived from 24 healhty people, and including other covariates in addition to weight, such as…
- Trial name
- NCT02155517
- Testing
- Evaluation of propofol effect
- Where
- Venezuela
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tiva Group