Clinical trials: Healthy Male Adults
Healthy Male Adults
A Pharmacokinetic Study of DE-117 Ophthalmic Solution in Healthy Adult Male Subjects - Phase I Study -
The purposes of this study are to evaluate the safety and plasma pharmacokinetics of DE-117 ophthalmic solution (one drop once daily for 7 days) in healthy male adults.
- Trial name
- NCT02650063
- Testing
- DE-117
- Where
- Japan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Santen Pharmaceutical Co., Ltd.
EGFR Mutant Advanced Non-small Cell Lung Cancer, Central Nervous System (CNS) Metastases
Material Balance of [14C]Zorifertinib in Healthy Adult Male Participants in China
This is a single-center, single-dose, open-label, Phase I study to evaluate the mass balance, biotransformation, pharmacokinetic characteristics, excretion pathways, and safety of a single oral 200 mg/5 µCi dose of…
- Trial name
- NCT07620951
- Testing
- [14C]Zorifertinib Oral Formulation
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Alpha Biopharma (Jiangsu) Co., Ltd.
Healthy Adult, Physical Condition
Isokinetic Strength and Anaerobic Capacity
This study aims to investigate differences in isokinetic knee extensor and flexor strength parameters among recreationally active young adult males classified into low, moderate, and high anaerobic power groups based on relative…
- Trial name
- ISAC (NCT07376551)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Uludag University
Healthy Volunteers, Renal Impairment
A Study About How ASP5354 Affects the Body in Healthy Adults and in Adults Whose Kidneys do Not Work Well
The ureter is the tube that carries urine from the kidneys to the bladder. It is difficult for surgeons to see the ureter during abdominal surgery. This could lead to injuring the ureter which, although rare, could be serious.
- Trial name
- NCT05495581
- Testing
- pudexacianinium chloride
- Where
- 4 sites in United States, Japan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
Healthy
Bioequivalence Study of Mycophenolate Mofetil 250 mg Capsule, Under Fed Conditions
An open-label, balanced, randomized, two-treatment, two-period, two sequence, single dose, crossover, bioequivalence study of Mycophenolate mofetil 250 mg Capsule of Dr.
- Trial name
- NCT01513057
- Testing
- Mycophenolate Mofetil
- Where
- India
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Opioid-Related Disorders, Pain, Acute
A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of Different Amounts of Tablets of a New and a Marketed Tablet Formulation in Healthy Adults
This clinical trial is being conducted to compare concentrations of hydrocodone and acetaminophen in the blood after administration of different amounts of tablets of a new and a marketed tablet formulation in healthy adults.
- Conditions
- Opioid-Related Disorders, Pain, Acute, Pain, Postoperative
- Trial name
- NCT03137030
- Testing
- GRT7014 - Abuse Deterrend Tablet, Norco 5Mg-325Mg Tablet
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Allergy
Relative Bioavailability Study to Evaluate Cetirizine HCl Gummy 10 mg and Cetirizine HCl Oral Tablets 10 mg
A Randomized, Open-Label, Single-Dose, Five-Period Crossover, Relative Bioavailability Study to Evaluate Cetirizine HCl Gummy 10 mg and Cetirizine HCl Oral Tablets 10 mg Administered in Healthy Adult Male and Female Subjects
- Trial name
- NCT04071821
- Testing
- cetirizine HCl Gummy, Zyrtec tablet 10mg
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seattle Gummy Company
Pain, Acute
Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Subjects
This study is designed to compare TRV130 to placebo and morphine to learn about its effects on pain relief and side effects.
- Trial name
- NCT02083315
- Testing
- TRV130 1.5 mg, TRV130 3 mg, TRV130 4.5 mg
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Trevena Inc.
Renal Disease, End-Stage, Renal Insufficiency, Chronic
Bosutinib In Subjects With Renal Impairment
This is a two-staged study of a single dose of 200 mg of bosutinib given to subjects with renal impairment and matching healthy volunteers.
- Conditions
- Renal Disease, End-Stage, Renal Insufficiency, Chronic, Renal Insufficiency, Acute
- Trial name
- NCT01233882
- Testing
- Bosutinib
- Where
- 5 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Pfizer
Glaucoma, Ocular Hypertension
Pharmacokinetic Study of OPC-1085EL Ophthalmic Solution in Healthy Male Adult Volunteers
OPC-1085EL ophthalmic solution, carteolol long-acting ophthalmic solution or latanoprost ophthalmic solution are administered once daily for 7 days and the effect on the blood concentration of carteolol and latanoprost in…
- Trial name
- NCT02108288
- Testing
- OPC-1085EL ophthalmic solution, Carteolol long-acting ophthalmic solution, Latanoprost ophthalmic solution
- Where
- Japan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Pulmonary Arterial Hypertension
Bioequivalence Study of Riociguat 2.5 mg Film Coated Tablets and Adempas (Riociguat) 2.5 mg Film Coated Tablets
Single dose oral bioequivalence study of Riociguat 2.5 mg film coated tablets and 'Adempas' (Riociguat) 2.5 mg Filmtabletten (film coated tablets) in healthy adult male subjects under fasting conditions.
- Trial name
- NCT06180096
- Testing
- Riociguat film coated tablets, Adempas Filmtabletten
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Healthy Adult Male and Female Volunteers, Mild Dyslipidemia
EDP167 in Healthy Volunteers and Subjects With Mild Dyslipidemia
EDP167 is a double-stranded small interfering RNA (siRNA) drug targeting ANGPTL3, which may bring benefits for patients with dyslipidemia conditions.
- Trial name
- NCT07412080
- Testing
- EDP167
- Where
- 2 sites in China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eddingpharm (Zhuhai) Co., Ltd.
Healthy Adult Chinese Males
A Study of the Pharmacokinetics of Golimumab in Chinese Male Subjects
The purpose of this study is to evaluate the pharmacokinetics of golimumab in Chinese male participants.
- Trial name
- NCT01288157
- Testing
- Golimumab
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centocor, Inc.
Healthy Male Adults Participants
Single-Dose Phase 1 Study of TAK-792
The purpose of this study is to characterize the safety and tolerability profile of TAK-792 when administered as a single oral dose in healthy Japanese and Caucasian male participants.
- Trial name
- NCT02448719
- Testing
- TAK-792 30 mg, TAK-792 100 mg, TAK-792 250 mg
- Where
- Japan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy Male Adults
Bioequivalence Between Single Administration of ASC-01 (Aripiprazole/Sertraline Combination Drug) and Concomitant Single Administration of Aripiprazole and Sertraline, and Food Effect on Pharmacokinetics of ASC-01 in Healthy Male Adults
To investigate the bioequivalence of aripiprazole between administration of one ASC-01 tablet (aripiprazole 3 mg/sertraline 100 mg combination drug) and concomitant administration of one aripiprazole 3-mg tablet and two…
- Trial name
- NCT03342963
- Testing
- ASC-01, Aripiprazole and sertraline
- Where
- Japan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Imumune Thrombocytopenia(ITP) Human Mass Balance
Human Mass Balance of [14C]HMPL-523 in Healthy Adult Male Chinese Subjects
To evaluate the absorption, metabolism and excretion of HMPL-523 in healthy male Chinese subjects following multiple oral doses of HMPL-523 tablets followed by a single oral dose of [14C]HMPL-523 suspension
- Trial name
- NCT05781906
- Testing
- HMPL-523, 150 µCi [14C]HMPL-523
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Hutchmed
Healthy Sedanters, Balance
The Acute Effect of Kinesio Taping on Balance and Proprioception
Kinesio tape will be applied to the leg muscles of two groups of healthy and young participants using a specific taping technique. After the application of the tape, assessments of balance and proprioception will be conducted.
- Conditions
- Healthy Sedanters, Balance, Proprioception
- Trial name
- NCT06965348
- Testing
- Application of kinesio tape
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Healthy
Study of the Safety, Tolerability and Pharmacokinetics of 611 in Adult Healthy Volunteers
This is a Phase 1 randomized, double blinded, placebo-controlled, single dose escalation study to evaluate the safety, tolerability, and PK of 611 in healthy volunteers.
- Trial name
- NCT04527718
- Testing
- 611
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
Creatine Absorption in Healthy Adults
Impact of OptiCreatine on Plasma Creatine and Gastrointestinal Effects in Males and Females
The study aims to evaluate the novel OptiCreatine formulation, which combines creatine with other bioactive compounds purported to enhance absorption and reduce gastrointestinal (GI) discomfort.
- Trial name
- NCT07225335
- Testing
- OptiCreatine, Creatine Monohydrate
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- TSI Group LTD
Semen Quality in Healthy Adult Men
Effects of 12-Week Combined Exercise on Semen Quality and Metabolic Health in Healthy Men
This study evaluated whether a 12-week combined aerobic and resistance exercise program could improve semen quality and metabolic health in healthy adult men. A total of 34 men aged 18-24 years participated in the study.
- Trial name
- NCT07778576
- Testing
- Combined Aerobic and Resistance Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University