Clinical trials: Healthy Male Participants
Cyclists, Healthy Adult Male
The Effects of Beta-Alanine Supplementation on Mechanical Performance, Acid-Base Balance, Oxidative Stress, and Enzymatic Antioxidant Defence During Repeated Wingate Anaerobic Tests Under Normoxic and Hypoxic Conditions
Beta-alanine is a dietary supplement that increases skeletal muscle carnosine concentration and may enhance the muscle's ability to buffer hydrogen ions produced during high-intensity exercise.
- Trial name
- NCT07650162
- Testing
- beta-alanine, normoxic conditions, Normobaric hypoxic conditions (≈2500 m)
- Where
- Poland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Healthy, Healthy Adult Male
AI-Based Hamstring Injury Risk Analysis and Effects of the FUNBALL Program
This study investigates hamstring injury risk in football players using artificial intelligence-based motion analysis (OpenPose) and evaluates the effects of a targeted exercise intervention (FUNBALL).
- Trial name
- NCT07650006
- Testing
- FUNBALL Prevention Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Healthy Adult Males, Healthy Subjects
Comparing The Effect of Proprioceptive Neuromuscular Facilitation (PNF) When Coupled With Dry Needling (DN), Acupuncture (AN) or Sham Needling (SN) on Knee Range of Motion (ROM), Jump Height and Unipedal Balance
Muscle tightness was found to increase injury risks. Muscle relaese techniques and needling were known to reduce muscle tightness, their specific influence on functional muscle performance remains inconclusive.
- Trial name
- NCT07612969
- Testing
- Proprioceptive Neuromuscular Facilitation with Dry Needling, Proprioceptive Neuromuscular Facilitation with Acupuncture, Proprioceptive Neuromuscular Facilitation
- Where
- Lebanon
- Volunteers
- 65 people
- Sponsor
- Mohamad Karam
Healthy Volunteers - Male and Female
TSPO Occupancy in the Human Lung
The investigators would like to explore the role of TSPO in PAH using a pharmacological challenge agent (XBD173) to modulate TSPO function.
- Trial name
- NCT07362290
- Testing
- XBD173
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Healthy Male and Female Subjects
Pharmacokinetics of Y-4 Tablets With Pregabalin Capsules and Riluzole Tablets in U.S. Healthy Participants
The primary goal of this clinical trial is to compare pharmacokinetic characteristics of Y-4 tablets with pregabalin capsules and riluzole tablets in the US healthy adult participants after single oral administration under fasted…
- Trial name
- NCT07618715
- Testing
- Y-4 tablet, Pregabalin capsule, Riluzole tablet
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Neurodawn Pharmaceutical Co., Ltd.
Healthy Male Adults Participants
A Study to Evaluate the PK Similarity of AK104 in Healthy Chinese Male Participations
This study is to evaluate the pharmacokinetic (PK) similarity of AK104 (an anti-PD-1/CTLA-4 bispecific antibody) from the proposed new manufacturing site and the approved original site in healthy male participants.
- Trial name
- NCT07619001
- Testing
- AK104 (New Site), AK104 (Original Site)
- Where
- China
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Akeso
Healthy Adult Male
Acute Effects of Caffeine on Repeated Sprint Performance and Energy Distribution
The goal of this study is to learn if low-dose caffeinated coffee improves repeated sprint performance and affects energy system contributions in combat sports athletes.
- Trial name
- NCT07596511
- Testing
- Cycling Repeated Sprint Test (6 × 10 s), Breath-by-Breath VO₂ Monitoring - COSMED K5, Capillary Blood Lactate Sampling (non-invasive)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Trabzon University
Healthy Adult Male
A Study to Assess the Pharmacokinetics of GEn-1124 After Single Oral Dosing in Healthy Subjects
The goal of this clinical trial is to determine the pharmacokinetics (how the body interacts with administered substances for the entire duration of exposure) of Gen-1124 in an oral formulation (taken by mouth) in healthy…
- Trial name
- NCT07185113
- Testing
- GEn-1124
- Where
- New Zealand
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- GEn1E Lifesciences
Healthy Adult Male
Effect of Gum Acacia and Electrolytes on Hydration After an Exercise-indued Dehydration
This clinical study is a single-blind, placebo-controlled, three-way cross-over trial evaluating the rehydration efficacy of two nutritional beverages compared to water, after one administration.
- Trial name
- NEX/008624 (NCT07570238)
- Testing
- Rehydration beverage
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nexira
Healthy Adult Male and Female Volunteers
Safety and PK Study of BICX104 With or Without Bupropion Compared to Vivitrol
Naltrexone (NTX), an opioid receptor antagonist, has a longstanding history of safe and effective use for the treatment of addictive disorders.
- Trial name
- NCT07269873
- Testing
- BICX104 naltrexone implantable pellet, Bupropion 150 mg XL, Naltrexone (depot)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BioCorRx Pharmaceuticals Inc
Healthy Adult Male
Effect of Collavant® n2 in Healthy Male Adults With Exercise-induced Joint Discomfort.
The present clinical study has been designed to evaluate the effect of Collavant® n2 at a daily dose of 40 mg on joint function and performance in healthy, amateur male runners with exercise-induced knee discomfort.
- Trial name
- COLLMOTION (NCT07561203)
- Testing
- Native type II collagen (Collavant® n2)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bioiberica
Nutrition, Healthy Male and Female Subjects
Influence of Food Texture on Appetite Control, Gastric Emptying, and Energy Expenditure
The aim of the study is to investigate the effect of liquid versus semi-solid meals on the regulation of energy balance in healthy young adults.The main questions it aims to answer are: Does a protein-rich liquid meal result in…
- Trial name
- NCT06853249
- Testing
- liquid meal, semi-solid meal, caloric drink + semi-solid meal
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Kiel
Healthy Male Volunteers Over 65
Assessing the Impact of a Leucine Enriched Whey Protein vs Isonitrogenous Whey on Muscle Protein Synthetic Responses in the Rested and Acute Post Exercise States in Older Adults
Occupying ~45-55% of body mass, skeletal muscle is the largest organ of the body and plays a pivotal role in locomotion, structural support and whole-body metabolic health.
- Trial name
- NCT06971822
- Testing
- Protein Supplementation
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Healthy Adult Male
Study on the Mass Balance of [14C]HRS-9190 for Injection in Healthy Participants
To evaluate the absorption, metabolism and excretion after a single intravenous bolus of [14C]HRS-9190 in healthy Participants
- Trial name
- NCT07494175
- Testing
- [14C] HRS-9190
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Healthy Male Adults, Food Effect in Healthy Volunteers
A Study to Evaluate the Effect of Food on the Bioavailability of AJ201, and Safety, Tolerability, and Pharmacokinetics of AJ201 in Japanese and White Healthy Male Participants
This is a Phase 1, randomized, single-dose, open-label, two-way crossover study to evaluate the effect of food on AJ201, and to evaluate the safety, tolerability, and pharmacokinetics of AJ201 in Japanese and White healthy male…
- Trial name
- NCT07549919
- Testing
- AJ201
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- AnnJi Pharmaceutical Co., Ltd.
Healthy Male Adults
To Evaluate the Mass Balance Recovery, Metabolite Profile and Metabolite Identification in Healthy Male Subjects
To Evaluate the Mass Balance Recovery, Metabolite Profile and Metabolite Identification in Healthy Male Subjects
- Trial name
- NCT07036458
- Testing
- 14C Epaminurad Oral Solution
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- JW Pharmaceutical
Healthy Volunteers - Male and Female
¹⁹F (Perfluoropropane) MRI
Healthy volunteers aged 18 to 85 will undergo ¹⁹F (perfluoropropane) MRI to support the development of imaging sequences, reconstruction algorithms, and hardware necessary for acquiring high-spatial resolution lung images.
- Trial name
- NCT07305532
- Testing
- 19F(perfluoropropane) MRI
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Alexei Ouriadov
Male, Healthy Volunteers
Effects of L-lysine on Adrenal Secretion
Data from the literature and previous in vitro research conducted in the investigators' laboratory (INSERM U413/EA4310, University of Rouen) suggest that adrenal corticosteroid secretion might be controlled by a paracrine…
- Trial name
- L-Lysine (NCT01220388)
- Testing
- L-lysine
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Healthy Volunteers - Male and Female
A Study of ORN252 in Healthy Participants
The purpose of this study is to assess the safety and tolerability of ORN252 in healthy adult participants.
- Trial name
- NCT07439796
- Testing
- ORN252
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Orna Therapeutics, Inc.
Healthy Adult Male
Effect of Early Time-Restricted Eating on Appetite, Appetite-Regulatory Hormones and Energy Intake
This randomised crossover study's primary aim is to investigate the effect of short-term fasting (eTRE) on subjective appetite and appetite-regulatory hormones (i.e., leptin, adiponectin, total glucagon-like peptide-1 (GLP-1)…
- Trial name
- NCT07500792
- Testing
- Normal diet, early Time-Restricted Eating (eTRE), instantaneous visual analogue scale (iVAS)
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Glasgow