Clinical trials: Healthy Men
Healthy Men
LDL Receptor Under Ezetimibe and Simvastatin
The purpose of this study is to investigate the effects of the two lipid -lowering drugs, ezetimibe and simvastatin, on lipid metabolism in humans.
- Trial name
- NCT00317993
- Testing
- ezetimibe, simvastatin, ezetimibe plus simvastatin
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Cologne
Glycemic Control, Gastrointestinal Hormone Response
Mechanism of Action of Milk and Its Components on Glycemic Control in Healthy Young Men
The investigators hypothesize that the physiological effects of milk on satiety and glycemic control are mediated by the interaction between its macronutrient components by both insulin-dependent and independent mechanisms.
- Conditions
- Glycemic Control, Gastrointestinal Hormone Response, Healthy Young Men
- Trial name
- NCT01812967
- Testing
- Milk Fat, Milk Protein, Lactose
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Older Men, Quality of Life
Effects of Resistance-Based Multicomponent Training Incorporating Respiratory Exercise on Diaphragm Thickness, Hepatic Attenuation, and Quality of Life in Healthy Older Men: A Randomized Controlled Trial
This randomized controlled trial investigated the effects of a four-week moderate-intensity resistance training program on diaphragm thickness, hepatic fat density, and health-related quality of life in healthy community-dwelling…
- Conditions
- Older Men, Quality of Life, Fatty Liver, Resistance Training
- Trial name
- RT-DIA-OLDER (NCT07449767)
- Testing
- Resistance Training Group (RT), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Schizophrenia
A Study of the Dose Proportionality of Extended Release Paliperidone
The purposes of this study are to evaluate the dose proportionality of 1.5- and 3 mg tablets of paliperidone ER, to document the pharmacokinetics of a 1.5 mg dose of paliperidone ER, and to assess the safety and tolerability of…
- Trial name
- NCT00791167
- Testing
- Paliperidone ER
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Sexual Dysfunction, Mediterranean Diet
Relationship Between Nutrition and Sexual Activity
Sexuality is integral to personality, influencing feelings, thoughts, actions, and physical and mental health. Female sexual dysfunction is a fairly common condition that covers four main areas: hypoactive sexual desire disorder…
- Conditions
- Sexual Dysfunction, Mediterranean Diet, Aphrodisiac Foods, Obesity
- Trial name
- NCT05632367
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Healthy Volunteers
Dose-Response of Gonadal Steroids and Bone Turnover in Older Men
The purpose of this study is to determine the levels of testosterone and/or estradiol at which changes in bone turnover, body composition, strength, sexual function etc. begin to occur in older men.
- Trial name
- NCT00114114
- Testing
- Testosterone, Goserelin acetate
- Where
- United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy Men and Women
Open-label Study Using 50 Mg Liquid Etanercept Subcutaneous Injection in the Thigh to Compare an Auto-injector Device and a Manual Injection in Healthy Subjects
A single-center, open-label, randomized study with a screening period of up to 21 days. Following that, eligible men and women will receive 50 mg of etanercept subcutaneously in the thigh to compare injection by auto-injection…
- Trial name
- NCT02588534
- Testing
- etanercept (ENBREL®) via auto-injector device, Etanercept (ENBREL®) via Manual injection
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Amgen
Healthy
A Study in Healthy Men to Test the Influence of BI 1358894 on the Amount of the Medicines Rosuvastatin and Dabigatran in the Blood
The main objective of this trial is to investigate the relative bioavailability of rosuvastatin (Reference 1, Part 1) and dabigatran (Reference 2, Part 2) given alone and together with BI 1358894 (Test 1, Test 2) following oral…
- Trial name
- NCT04099732
- Testing
- Rosuvastatin, BI 1358894, Dabigatran etexilate
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy Men to Test Whether Carbamazepine Influences the Amount of Nerandomilast in the Blood
The main objective of this trial is to investigate the effect of carbamazepine on pharmacokinetics of nerandomilast.
- Trial name
- NCT07100964
- Testing
- nerandomilast, carbamazepine
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Metabolic Health
Effects of Two-weeks of Time Restricted Feeding on Basal and Postprandial Metabolism in Healthy Men
In the modern era, food access is widely available and it is not uncommon for the time between breakfast and a late night snack to exceed 14 hours.
- Trial name
- TRF (NCT03969745)
- Testing
- Time restricted feeding, Caloric restriction
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Healthy
A Study in Healthy Men to Test How Well Different Doses of BI 1839100 Are Tolerated (1490-0001)
This trial starts the clinical development of BI 1839100. Effects of single rising doses of BI 1389100 on safety, tolerability and pharmacokinetics will be assessed as basis for further development in patients with pulmonary…
- Trial name
- NCT05354453
- Testing
- BI 1839100, allyl isothiocyanate (AITC)
- Where
- Netherlands
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Metabolic Availability of Methionine From Chickpeas in Adult Men
The research study is being done so we can determine the quality of the protein present in Canadian chickpeas. Amino acids are the building blocks of protein and protein quality is determined by the amount of amino acids present…
- Trial name
- NCT03339154
- Testing
- Dietary Intakes
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Healthy
Study That Evaluates the Effect of CYP3A4 Inhibition on Lu AG06466 in Healthy Men and Women
A study to learn how a drug (itraconazole) that is known to inhibit a certain enzym in the liver, impacts the body's ability to breakdown Lu AG06466 into breakdown products in healthy men and women.
- Trial name
- NCT04405323
- Testing
- Lu AG06466, Itraconazole
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy
A Trial in Healthy Men and Women to Find Out How Well Different Doses of BI 1291583 Are Tolerated
The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 1291583 in healthy male and female subjects following administration of multiple rising doses over 4 weeks and to explore…
- Trial name
- NCT04866160
- Testing
- BI 1291583
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 894416 in the Blood
The main objective of this trial is to investigate the relative bioavailability of BI 894416 in plasma when given as oral single dose together with multiple oral doses of itraconazole (Test,T) as compared to when given alone as…
- Trial name
- NCT03722173
- Testing
- Itraconazole, BI 894416
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Men and Women
Effects of Corn and Coconut Oils on Lipoprotein Lipids, Insulin Sensitivity and Inflammation
The objectives of this trial are to assess the effects of corn oil and coconut oil on low-density lipoprotein cholesterol (LDL-C) concentrations, and other aspects of the fasting lipoprotein lipid profile, as well as insulin…
- Trial name
- NCT03202654
- Testing
- Corn Oil, Coconut Oil
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Healthy
A Study in Healthy Japanese Men to Test How Well Different Doses of BI 765845 Are Tolerated
The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 765845 in healthy male Japanese subjects following intravenous administration of single rising doses.
- Trial name
- NCT06139341
- Testing
- BI 765845
- Where
- Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Muscle Strength Development, Muscle Strength
Acute Effects of Proprioceptive Neuromuscular Facilitation on Hamstring-to-Quadriceps Strength Ratio
This study aimed to compare the acute effects of proprioceptive neuromuscular facilitation (PNF) and static stretching on hamstring-to-quadriceps (H/Q) strength ratios in healthy young men.
- Conditions
- Muscle Strength Development, Muscle Strength, Neuromuscular Function
- Trial name
- Acute Effects (NCT07589712)
- Testing
- PNF Stretching, Static Stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Healthy Subjects
Circulating Levels of Irisin in Healthy Young Subjects
Irisin, a newly discovered myokine induced in exercise, has potential effects in stimulating adipose tissue browning, fighting obesity and diabetes.
- Trial name
- IRISSAS (NCT01986530)
- Testing
- Boost, Aerobic exercise
- Where
- Greece
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- 424 General Military Hospital
Healthy
Study to Assess Tolerability, Safety and Pharmacokinetics of a New Drug
The purpose of this study is evaluate the safety and tolerability parameters regarding the new drug in healthy men and evaluate the pharmacokinetics parameters after one dose and multiple doses of the new drug.
- Trial name
- ACH15 (NCT01702675)
- Testing
- ACH15 50 mg, ACH15 250 mg, ACH15 500mg
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.