Clinical trials: Healthy Older Adults
Age-related Cognitive Decline
A Group Study on the Effects of a Short Multi-Domain Cognitive Training in Healthy Elderly Italian People
Alongside physiological cognitive ageing, nowadays there is an alarming increase in the incidence of dementia that requires communities to invest in its prevention.
- Trial name
- NCT03771131
- Testing
- Multi-domain cognitive training
- Where
- Italy
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Healthy Volunteers
A Study To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2086 in Healthy Adult and Elderly Participants
The primary objective of this study is to evaluate the safety and tolerability of E2086 following administration of a single oral doses in healthy adult and elderly participants.
- Trial name
- NCT05745207
- Testing
- E2086
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Older Adults (65 Years and Older), Cognition
Effects of Breathing Exercises on Cognition in Older Adults
The goal of this interventional clinical trial is to investigate the effects of breathing exercises added to balance training on cognitive function in individuals aged 65 years and older.
- Conditions
- Older Adults (65 Years and Older), Cognition, Balance Control in Elderly, Fall Prevention in Healthy Aging
- Trial name
- NCT07505914
- Testing
- Balance Training Program, Inspiratory Muscle Training, Breathing Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Healthy
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Doses
The primary objective of this trial was to investigate safety and tolerability of multiple doses of BI 409306 in healthy young and elderly volunteers.
- Trial name
- NCT01505894
- Testing
- BI 409306
- Where
- Germany
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Amnestic Mild Cognitive Impairment, Aging
Recollection Training in Healthy Older Adults and Older Adults With Amnestic Mild Cognitive Impairment
We have developed a training intervention that successfully improves older adults' memory. We have also shown that older adults whose memory is as good as younger adults' memory (Hi-Old) use an altered pattern of memory-related…
- Trial name
- NCT00643266
- Testing
- Recollection Training, Control
- Where
- Canada
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Baycrest
Dengue Fever
Safety and Immunogenicity of Different Schedules of Takeda's Tetravalent Dengue Vaccine Candidate (TDV) in Healthy Participants
The purpose of this study is to assess the humoral immune responses to three different dose schedules of Takeda's Tetravalent Dengue Vaccine Candidate (TDV) administered subcutaneously in healthy participants between 2 and <18…
- Trial name
- NCT02302066
- Testing
- Takeda's Tetravalent Dengue Vaccine Candidate (TDV)
- Where
- 3 sites in Dominican Republic, Panama and 1 more
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Takeda
Hepatitis B
Study of Recombinant Modified Process Hepatitis B Vaccine in Older Adults (V232-059)(COMPLETED)
The purpose of this trial is to determine if there is an improvement in the immune response of older adults over 50 years of age using a modified process hepatitis B vaccine and a currently licensed hepatitis B vaccine…
- Trial name
- NCT00440531
- Testing
- Comparator: RECOMBIVAX HB™ Hepatitis B Vaccine (Recombinant), Comparator: Modified Process Hepatitis B Vaccine (Experimental), Comparator: ENGERIX-B™ (currently licensed product)
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Mild Cognitive Impairment, Dementia
SCGs as a Proxy for Determining the Cognitive Status of Older Adults
Detecting memory problems early is crucial for treating conditions like Mild Cognitive Impairment (MCI), which often leads to dementia. Currently, doctors use tests in clinics to check for these issues.
- Conditions
- Mild Cognitive Impairment, Dementia, Alzheimer Disease, Healthy Aging
- Trial name
- NCT06367231
- Testing
- VibrantMinds
- Where
- 8 sites in Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Human Influenza
Safety and Immunogenicity of a Subunit Trivalent Influenza Vaccine, Northern Hemisphere Formulation 2013/2014, in Healthy Adults Aged 18 Years and Above
The present study is designed to confirm the safety and immunogenicity of trivalent, surface antigen, inactivated influenza vaccine in 2 age cohorts: 18 to ≤60 years and ≥61 years.
- Trial name
- NCT01879553
- Testing
- TIV
- Where
- Belgium
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Diabetes, Healthy
Comparison of the Effect of Liraglutide in Young Versus Elderly Healthy Volunteers
This trial is conducted in Europe. The aim of this trial is to compare the exposure of liraglutide in young versus elderly healthy subjects.
- Trial name
- NCT01507337
- Testing
- liraglutide
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Frailty at Older Adults
Motivational Support for an Autonomous Exercise Program for Healthy Aging
An effective implementation of an exercise programme such as VIVIFRAIL, in an unsupervised mode, requires a careful consideration of the patient's motivational traits and state, and the adaptation of the interventions to the…
- Trial name
- MOTIVA (NCT07447453)
- Testing
- MOTIVA ecosystem
- Where
- 2 sites in Spain
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Getafe
Infectious Disease, COVID-19
Safety and Immunogenicity of RVM-V001 in Healthy Individuals Previously Vaccinated With BNT162b2 and mRNA-1273
Phase 1, open-label, dose-escalation study to evaluate the safety, tolerability, and immunogenicity of RVM-V001 administered as a single intramuscular injection in healthy adults.
- Trial name
- NCT05420077
- Testing
- RVM-V001 10 µg, RVM-V001 30 µg, RVM-V001 60 µg
- Where
- 2 sites in Australia
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- RVAC Medicines (US), Inc.
Elderly People
Improving the Quality of Life of Elderly Individuals Living in Nursing Homes
The development of physical activity (PA) and exercise habits improves strength, flexibility, balance and coordination, activities such as walking, sleep quality and cognitive status in elderly people and supports their…
- Trial name
- NCT06520956
- Testing
- Video based exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Galata University
Pneumococcal Infections
Study Evaluating Safety and Immunogenicity of 13-Valent Pneumococcal Conjugate Vaccine With Influenza Vaccine in Adults
The 13-valent pneumococcal conjugate vaccine (13vPnC) is being developed for adults to prevent pneumococcal diseases such as meningitis (inflammation of the brain lining), septicemia (blood poisoning), and pneumonia (inflammation…
- Trial name
- NCT00492557
- Testing
- 13-valent pneumococcal conjugate vaccine, 13vPnC + TIV
- Volunteers
- 1,185 people, healthy volunteers welcome
- Sponsor
- Pfizer
Stroke, Healthy
Gait Pattern Analysis and Feasibility of Gait Training With a Walking Assist Robot in Stroke Patients and Elderly Adults
The purpose of this study was to investigate the effects of the new wearable hip assist robot developed by Samsung Advanced Institute of Technology (Samsung Electronics Co, Ltd., Korea) to gait rehabilitation in elderly adults…
- Trial name
- NCT02843828
- Testing
- gait rehabilitation with Samsung Hip Assist v1, gait rehabilitation without Samsung Hip Assist v1
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Samsung Medical Center
Frail Elderly, Malnutrition
Healthy Life for Frail Malnourished Seniors Performed Together With Trained Lay Buddies
Background: In elderly subjects frailty and malnutrition are very common and can lead to serious health hazards, increase mortality, morbidity, dependency, institutionalization and a reduced quality of life.
- Trial name
- NCT01991639
- Testing
- Nutritional and physical activity intervention
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Influenza
Safety and Immunogenicity of Three Commercially Available Influenza Vaccines in Children Aged 6 to <36 Months
This phase IV protocol is designed to evaluate the safety, clinical tolerability and immunogenicity of the 2005-2006 formulation of three widely used conventional influenza vaccines in children aged 6 to 35 months
- Trial name
- NCT00311428
- Testing
- Influenza
- Where
- Finland
- Volunteers
- 270 people
- Sponsor
- Novartis
Infections, Rotavirus
Assess the Immunogenicity & Safety of 2 Doses of Oral Live Attenuated Human Rota(HRV)Vaccine in Healthy Infants in India
Rotavirus disease is the most common cause of gastroenteritis and dehydration in young children worldwide. The global public health burden has prompted the development of a human rotavirus vaccine against rotavirus disease by…
- Trial name
- NCT00289172
- Testing
- Live attenuated human rotavirus vaccine
- Where
- 4 sites in India
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
65 Years Older, Requires IADL Support
Bring Communities and Technology Together for Healthy Aging
Technology has been created to help older adults age well in their homes, but adoption and acceptance have been slow. The researchers are developing a low-cost web-based technology, called Elder Tree, for older adults and…
- Conditions
- 65 Years Older, Requires IADL Support, Past Year History of Falls and/or Hospitalization
- Trial name
- ElderTree (NCT02128789)
- Testing
- Elder Tree website
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of Wisconsin, Madison
Healthy
PK Comparison of 6mg and 12mg EMSAM in Elderly vs. Non-Elderly
Evaluate the effect of age on the PK of two different doses of EMSAM.
- Trial name
- NCT00532116
- Testing
- EMSAM (Selegiline Transdermal System) 6mg, EMSAM (Selegiline Transdermal System) 12mg
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Somerset Pharmaceuticals
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.