Clinical trials: Healthy Participants, open to volunteers
Healthy, Obesity
New Heart Imaging Techniques to Evaluate Possible Heart Disease
Background: Imaging tests, such as magnetic resonance imaging (MRI), can provide information about heart and blood vessels. The tests let doctors can see the amount of blood vessel narrowing and vessel wall thickness.
- Conditions
- Healthy, Obesity, Diabetes, Healthy Volunteers
- Trial name
- NCT01399385
- Testing
- MR Imaging Techniques - 1, MR Imaging Techniques - 2, MR Imaging Techniques - 3
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healthy, Overweight and Obesity
Breathing & Blood Pressure
The purpose of this study is to determine the effect of obesity on cardiovascular responses during various breathing maneuvers.
- Trial name
- NCT05632406
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Florida State University
Healthy
A Study of LY4088044 in Healthy Participants
The purpose of this study is to evaluate how well LY4088044 is tolerated and what side effects may occur in healthy participants.
- Trial name
- NCT07090785
- Testing
- LY4088044
- Where
- 6 sites in United States, New Zealand and 1 more
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Aging, Frailty
Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults
This is a randomized, double-blind, placebo-controlled, two-arm crossover clinical trial evaluating the effects of nicotinamide mononucleotide (NMN) combined with trimethylglycine (TMG) supplementation, compared to NMN alone.
- Conditions
- Aging, Frailty, Exercise Tolerance, Healthy Male and Female Subjects
- Trial name
- NCT07144527
- Testing
- NMN and TMG (Euexia), Nicotinamide Mononucleotide (NMN)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Scott Silveira
Healthy Volunteers, Chronic Kidney Disease
A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney Disease
The goal of this clinical trial is to observe the safety of IGT-303 in healthy volunteers and participants with Chronic Kidney Disease.
- Trial name
- NCT07231679
- Testing
- IGT-303
- Where
- 13 sites in United States, Australia and 2 more
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Ingenia Therapeutics INC
Epilepsy, Drug-resistant Focal Epilepsy
Impact of Epilepsy on the Brainstem Adenosine Pathway and Its Relation With Arousal and Respiratory Reactivity
Despite the continuous development of new antiseizure medications over the past 25 years, 30% of patients with epilepsy suffer from drug-resistant seizures and are at risk of epilepsy-related complications, like cognitive…
- Conditions
- Epilepsy, Drug-resistant Focal Epilepsy, Healthy Controls
- Trial name
- BRAVE (NCT07249034)
- Testing
- 1 Hypercapnic challenge while participant is awake, PET/MRI acquisition
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Healthy Participants
Physiological and Neurocognitive Responses to Multisensory Food Cues in VR
This study aims to investigate how food cravings change when visual food cues are enriched with sound, smell, and interactive experiences in a virtual reality (VR) environment.
- Trial name
- NCT07320209
- Testing
- Real food, Virtual Reality Food
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Marmara University
Healthy Volunteer, Atopic Dermatitis
First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis
This study will test a study medicine called REGN20423 to see how effective it is in healthy participants (in Part A) and participants with atopic dermatitis (eczema) (in Part B).
- Trial name
- AURA-AD (NCT07527923)
- Testing
- REGN20423
- Where
- 7 sites in United States, Belgium
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Healthy Participants
A Phase 1 Study of Navlimetostat Tablet Formulations
This study aims to compare the PK of Navlimetostat after administration of a wet-granulation tablet versus the dry-granulation tablet formulation in healthy adult female
- Trial name
- NCT07544628
- Testing
- Navlimetostat
- Where
- 4 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Healthy Adult Participants
Yeast Protein for Muscle Mass
Protein supplementation is said to be one of the cost-efficient and practical strategies to meet protein needs for growth and exercise, and can help maximize muscle gain from resistance exercise.
- Trial name
- NCT07561619
- Testing
- Yeast Protein, Resistance Training Exercises, Whey Protein
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Healthy Volunteer
Neural Mechanisms of Emotion-behaviour Interactions
Deciding what to do when for how long - self-organizing one's behaviour - is an important feature of daily life. Emotions arise providing short-cuts for the computational complexities.
- Trial name
- EMOBB (NCT07623746)
- Testing
- Functional Magnetic Resonance Imaging (fMRI)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Skin Barrier Dysfunction, Healthy Volunteers
Effect of FPP on Cutaneous Barrier Integrity
This pilot study will test how Fermented Papaya Preparation (FPP) impacts overall TEWL of areas that commonly display diminished barrier function, such as the skin from face, arms, and hands.
- Trial name
- FPP OSATO (NCT07725835)
- Testing
- Fermented Papaya Preparation (FPP)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthy Volunteer
A Study to Learn How ASP3082 is Processed in Healthy Men
Setidegrasib (ASP3082) is being developed for certain cancers. In this study, the researchers want to understand how it is processed by the body in healthy male volunteers.
- Trial name
- NCT07773129
- Testing
- 14C-labeled ASP3082
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
Healthy Participants, Healthy Adult Subject
Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks: Acute Postprandial Study
The goal of this clinical trial is to learn how eating different snack foods affects acute hunger, energy intake and eating behaviour in healthy adults. The study will be conducted remotely over 5 days.
- Conditions
- Healthy Participants, Healthy Adult Subject, Healthy Subjects, Healthy Adult Volunteer
- Trial name
- SMARTEATS-PP (NCT07776418)
- Testing
- High-fibre plant-based snack bar, Control snack bars
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Healthy Aging
Vicia Faba Peptides and Resistance Training in the Elderly
This randomized, double-blind, placebo-controlled clinical trial aims to investigate the effects of supplementation with peptides derived from Vicia faba L.
- Trial name
- NCT07858292
- Testing
- Vicia faba L.-derived peptides, Supervised Resistance Training
- Where
- Brazil
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Universidade Cesumar (UNICESUMAR)
Healthy Participants, Gastrointestinal Neoplasms
A Study to Investigate the Effect of Omeprazole and Cyclosporine on Velzatinib in Healthy Participants
This study will look at how two commonly used medicines, omeprazole and cyclosporine, influence the way the body absorbs, processes, and eliminates velzatinib in healthy volunteers.
- Trial name
- NCT07862114
- Testing
- Velzatinib, Cyclosporine, Omeprazole
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
A Clinical Trial of MK-6916 With Midazolam and Rosuvastatin in Healthy Participants (MK-6916-012)
Researchers are looking for new treatments for pain. The goal of this trial is to learn if MK-6916 changes what happens to the midazolam and rosuvastatin in healthy participants' bodies.
- Trial name
- NCT07862621
- Testing
- Midazolam, Rosuvastatin, MK-6916
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Healthy Skin, Skin Hydration
Evaluation of SPM™ Topical Cosmetic Application on Skin Appearance, Hydration, and Barrier Support in Healthy Adults
This is an exploratory, cosmetic-use study evaluating the effects of Super Protein Multifunction (SPM™), a topical peptide-based formulation, on skin appearance, hydration, and barrier-related characteristics in healthy adults.
- Trial name
- SPMT (NCT07236736)
- Testing
- Skin biopsy, Corneometer® Measurement, Tewameter® Measurement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Biocoz Global Pte. Ltd.
Fertility, Fertility, Male
Plan A Occlusion and Reversal System Feasibility Study
Prospective, multicenter, single-arm, open label, interventional clinical trial investigating the safety and effectiveness of the Plan A Male Contraceptive System to occlude the vas deferens to block the passage of sperm and then…
- Conditions
- Fertility, Fertility, Male, Healthy Male Adults
- Trial name
- NCT07361120
- Testing
- Occlusion System
- Where
- 3 sites in Australia, Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Next Life Sciences
Healthy Volunteers
SAD and MAD Study of AKB-9090 in Healthy Adult Participants
This is a first-in-human (FIH study designed to evaluate safety, tolerability, pharmacokinetic, and pharmacodynamic effects of AKB-9090 in healthy adult participants.
- Trial name
- NCT07429006
- Testing
- AKB-9090
- Where
- New Zealand
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Akebia Therapeutics