Clinical trials: Heart Attack Patients
Acute Myocardial Infarction
The Impact of Early Cardiac Rehabilitation of AMI Patients on the Incidence of Post-infarction HF
Background: Acute myocardial infarction (AMI) is the second cause of death worldwide. After AMI, the heart failure (HF) is a main cause of patient rehospitalization and death.
- Trial name
- NCT03528382
- Testing
- Cardiac rehabilitation quality improvement system
- Where
- China
- Volunteers
- 3,103 people, healthy volunteers welcome
- Sponsor
- Yu Bo
Anterior Myocardial Infarction, Heart Failure
Effect of Intravenous Metoprolol Combining RIC on Myocardial Protection in STEMI Patients
The main purpose of this study is to compare the myocardial protection effect of intravenous metoprolol combined with remote ischemic conditioning (RIC) and single treatment before reperfusion in Chinese patients with anterior…
- Trial name
- NCT03579914
- Testing
- Metoprolol Injectable Product, Romote Ischemic Conditioning (RIC), Metoprolol & RIC
- Where
- 16 sites in China
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Harbin Medical University
Cardiogenic Shock,, With ECMO or IABP Support,
The Analysis of Heart Rate Variability With 24hrs Holter ECG and Serum Cardiac Fibrosis Markers in Critical Illness Patients Who Are With Cardiogenic Shock, With ECMO or IABP Support, or With APACH II Score >25)
The study is to show the prognostic factor of HRV parameter and cardiac fibrosis markers in critical illness patients
- Conditions
- Cardiogenic Shock,, With ECMO or IABP Support,, With APACH II Score >25)
- Trial name
- NCT01993745
- Where
- Taiwan
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
STEMI - ST-segment Elevation Myocardial Infarction
Metabolic Characteristics of Plasma OxPLs in STEMI Patients.
The goal of this observational study is to investigate the structural composition and metabolic characteristics of OxPLs in ST-segment elevation myocardial infarction(STEMI) patients.
- Trial name
- NCT07382700
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Ningbo University
Cardiac Arrest
Anti-inflammatory Effect of Therapeutic Hypothermia in Out-hospital Cardiac Arrest Patients With Cardiogenic Shock
Acute myocardial infarction complicated with cardiogenic shock trigger IL-6, the strong inflammatory response, result in multiple organ failure, even death.
- Trial name
- NCT02633358
- Testing
- Therapeutic hypothermia group
- Where
- Taiwan
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Myocardial Infarction
Heart Attack Research Program: Platelet Sub-Study (HARP)
This prospective observational cohort study, will investigate the platelet phenotype, platelet genetic composition, and role of platelets as effector cells in women and men with myocardial infarction (MINOCA or MI-CAD) and…
- Trial name
- HARP (NCT03022552)
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Myocardial Ischemic-reperfusion Injury
Immunometabolic Pattern of Intermittent Hypoxia During ST-segment Elevation Myocardial Infarction
The aim of this study is to characterize the protective pattern of intermittent hypoxia, angina pectoris and remote ischemic conditioning, in reperfusion injury by determining and monitoring the plasma immunometabolic parameters…
- Trial name
- NCT05230966
- Testing
- Remote Ischemic Conditioning (RIC)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Center Rijeka
Myocardial Infarction, Comorbidity
Web-Enhanced Guideline Implementation for Post MI CBOC Patients
To assist busy primary care clinicians in VA Community Based Outpatient Clinics (CBOCs) in managing complex patients by providing a single, interactive, and personalized source of information regarding applicable guidelines for…
- Trial name
- VA MI Plus (NCT00126750)
- Testing
- VA MI Plus Interactive
- Where
- 41 sites in United States, Puerto Rico
- Volunteers
- 847 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
ST Elevation Myocardial Infarction
SNPs in the DNase 1 Gene Impair Its Activity and Are Increased in a STE-ACS Patient Cohort Compared to Healthy Controls
Neutrophil extracellular traps (NETs) and deoxyribonuclease (DNase) activity determine outcome in ST elevation acute coronary syndrome (STE-ACS). DNase single nucleotide polymorphisms (SNPs) were increased in a japanese cohort.
- Trial name
- NCT02615015
- Testing
- Blood draw
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Chest Pain, Heart Attack
Henry Ford Heart Score Randomized Trial: Rapid Discharge of Patients Evaluated for Possible Myocardial Infarction
This was a prospective randomized, controlled trial designed to quantify the reduction in cost and length of stay of early discharge of emergency department patients evaluated for acute myocardial infarction, who are deemed to be…
- Conditions
- Chest Pain, Heart Attack, Coronary Artery Disease
- Trial name
- NCT03058120
- Testing
- Deferral of admission for stress test
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Ulcerative Colitis, Myocardial Infarction
Estimation of Cardiovascular Risk in Patients With Crohn's Disease and Ulcerative Colitis (PROVACI)
Inflammatory bowel diseases (IBD) are progressively increasing their prevalence worldwide. Up to half of patients may also have extraintestinal manifestation and cardiovascular diseases (CVDs) is one of the most relevant, being…
- Conditions
- Ulcerative Colitis, Myocardial Infarction, Stroke, Ischemic Heart Disease
- Trial name
- PROVACI (NCT07095634)
- Where
- Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Myocardial Infarction, Percutaneous Coronary Intervention
Circulating PRCP in STEMI Patients Undergoing Primary PCI
Purpose: The purpose of this study is to evaluate the impact of acute ST-segment elevation myocardial infarction (STEMI) and primary percutaneous coronary intervention (PCI) on circulating prolylcarboxypeptidase (PRCP) level and…
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, PRCP
- Trial name
- NCT02772133
- Testing
- Primary PCI
- Where
- 4 sites in China
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Myocardial Infarction
Role of Oxytocin in Myocardial Infarction
60 patients admitted to this ICCU at the Sheba medical Center will be randomly divided in to 2 groups. one group will receive the conventional treatment while the second group will receive the conventional treatment plus oxytocin…
- Trial name
- NCT03001635
- Testing
- Oxytocin
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Myocardial Infarction, Acute Coronary Syndrome
Aspirin Dose Comparison in Elderly PCI Patients: 30mg vs. 75mg in Acute Coronary Syndrome
Elderly patients undergoing percutaneous coronary intervention (PCI) face a high risk of both ischemic and hemorrhagic complications necessitating antiplatelet therapy.
- Trial name
- LowASA-PCI (NCT06254391)
- Testing
- Low-dose aspirin
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Myocardial Infarction
Prediction of Coronary Artery Disease Severity by Epicardial Adipose Tissue Thickness
is to test the hypotheses that epicardial adipose tissue can be a marker of severity of coronary artery disease in myocardial infarction patients
- Trial name
- NCT03308539
- Testing
- echocardiography and cardiac magnetic resonance
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Osama Fekry
Acute Myocardial Infarction
Effects of Tai Chi Chuan in Patients After Recent Acute Myocardial Infarction
This is a randomized Clinical Trial to assess the effects of Tai Chi Chuan on blood pressure, respiratory muscle strength and functional capacity in patients after recent acute myocardial infarction.
- Trial name
- NCT01340716
- Testing
- Tai Chi Chuan exercise, stretching exercise
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Myocardial Infarction
The Impact of Early Follow-up on Readmission Rates in AMI Patients
With no prior prospective study to demonstrate the benefit of an early post-discharge follow-up appointment in reducing readmission rates in the post-myocardial infarction (MI patient population, we propose to conduct the first…
- Trial name
- NCT02276456
- Testing
- Follow-up Appointment- early vs standard
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Duke University
Acute Myocardial Infarction, Heart Attack
Acute Coronary Syndrome and Care-Seeking Delay: A Web Based Behavioral Study
The primary aim of this study is to increase our understanding of care-seeking behavior surrounding heart attacks or acute coronary syndromes [ACS].
- Conditions
- Acute Myocardial Infarction, Heart Attack, Acute Coronary Syndrome, Unstable Angina
- Trial name
- NCT01407146
- Where
- United States
- Volunteers
- 2,381 people, healthy volunteers welcome
- Sponsor
- Yale University
ST Elevation Myocardial Infarction
The Predictive Value of eGFR for Adverse Cardiovascular Events in Patients With STEMI
Estimated glomerular filtration rate(eGFR) is significantly reduced in patients with ST-segment elevation myocardial infarction (STEMI).
- Trial name
- NCT03984071
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Dongying Zhang
Coronary Heart Disease, Myocardial Infarction
Prospective Coronary Heart Disease Cohort
To evaluate the biomarkers for the prognosis of coronary heart disease, patients with coronary heart disease will be recruited and followed up for at least 2 years.
- Trial name
- NCT05699629
- Where
- China
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- Shandong First Medical University