Clinical trials: Heart Catheterization
Newborn Morbidity
Efficacy of Direct CAtheterisation of the OMbilical Vein in Emergency Through Wharton's Jelly
The aim of this study is to demonstrate, with a good level of evidence, the efficacy, safety and feasibility of placing an umbilical route through Wharton's jelly, in the context of emergency situations in the delivery room.
- Trial name
- CaDOm (NCT06915467)
- Testing
- Umbilical vein catheterization through Wharton's jelly procedure
- Where
- 5 sites in France
- Volunteers
- 26 people
- Sponsor
- Hôpital NOVO
Cardiac Catheterization
Sugammadex Versus Neostigmine in Pediatric Less Than Two Years Undergoing Cardiac Catheterization
This study hypothesizes that Sugammadex may has more appropriate recovery profile than neostigmine in pediatric cardiac patients undergoing cardiac catheterization.
- Trial name
- NCT04258007
- Testing
- Reversal Neostigmine, Reversal Sugammadex
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Radial Artery Occlusion
Radial Versus Femoral Arterial Access for Cardiac Catheterization: Comparison of Complications at 30 Days
Cardiac catheterization has traditionally been performed via access to the arterial circulation from the femoral artery located in the groin.
- Trial name
- NCT01019330
- Testing
- Allen's test, Distal pulses
- Where
- 2 sites in United States
- Volunteers
- 243 people
- Sponsor
- Creighton University
Coronary Disease, Percutaneous Coronary Intervention
Fractional Flow Reserve and Instantaneous Free-wave Ratio Revascularization Strategies in Women
A real world study to evaluate outcomes in women based on guideline identified fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) cutoffs for ischemia (ischemia defined as FFR ≤ 0.80 and iFR ≤ 0.89).
- Conditions
- Coronary Disease, Percutaneous Coronary Intervention, Exercise Test, Myocardial Perfusion Imaging
- Trial name
- FiRST (NCT04599192)
- Testing
- No study intervention
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Yale University
Pulmonary Hypertension, Precapillary Pulmonary Hypertension
Correlation Between CT Pulmonary Angiography Metrics and Right Heart Catheterization Parameters in Pre-Capillary Pulmonary Hypertension
Pulmonary hypertension (PH) is a hemodynamic and pathophysiological condition defined by a mean pulmonary artery pressure (mPAP) greater than 20 mmHg at rest, as confirmed by right heart catheterization (RHC) (1).
- Conditions
- Pulmonary Hypertension, Precapillary Pulmonary Hypertension, Right Heart Catheterisation, CT Angiography
- Trial name
- NCT07667595
- Testing
- right heart catheter
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cardiac Catheterization, Endotracheal Tube
Ultrasound-detectable Endotracheal Tube: a Feasibility Study
The researchers are studying whether special features make it easier to see if the breathing tube is in the correct place. It is hoped that the investigational device will enable more accurate placement (depth and trachea vs.
- Trial name
- NCT05941013
- Testing
- Ultrasound detectable cuffed endotracheal tube (USD-ETT)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- John R. Charpie
Fasting, Cardiac Catheterization
Comparison Between Fasting and no Fasting Before Interventional Coronary Intervention on the Occurrence of Adverse Events
Traditionally, patients are asked to fast prior to invasive cardiac procedures. There exists neither clear evidence nor guidance about the benefits of this.
- Conditions
- Fasting, Cardiac Catheterization, Percutaneous Coronary Intervention
- Trial name
- TONIC (NCT04116346)
- Testing
- Oral intake allowed
- Where
- France
- Volunteers
- 736 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac Catheterization, Radiation Exposure
Reduce Radiation Exposure in Fluoroscopic Interventions Evaluation
The purpose of this study is to determine whether the ControlRad system device when installed in Fluoroscopic (x-ray) machine reduces radiation dose to operators (Doctors and nurses) and to the patient who is undergoing cardiac…
- Trial name
- REDEFINE (NCT04404257)
- Testing
- ControlRad System, Without ControlRad System
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Corewell Health East
Angiocardiography
The Safety and toleRability of UltraviSt in Patients Undergoing Cardiac CaTheterization (TRUST)
This study is to collect the information of Ultravist® in the patients indicated for the coronary angiography or PCI, like rate of ADR in patients, the dose for different indications, image quality to prove Ultravist the good…
- Trial name
- TRUST (NCT01206257)
- Testing
- Iopromide (Ultravist, BAY86-4877)
- Where
- China
- Volunteers
- 17,513 people
- Sponsor
- Bayer
Pulmonary Arterial Hypertension
Effects of Pulmonary Hypertension Therapy in Atypical Pulmonary Arterial Hypertension
The purpose of this study is to characterize the clinical and hemodynamic response of Pulmonary Arterial Hypertension (PAH) therapy in patients with atypical PAH and risk factors for left heart disease.
- Trial name
- NCT04787445
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Mayo Clinic
Coarctation of the Aorta
Coarctation Of the Aorta Stent Trial
The purpose of this study is to determine whether Cheatham Platinum bare metal stents are safe and effective in the treatment of native and recurrent aortic coarctation in selected children, adolescents and adults.
- Trial name
- COAST (NCT00552812)
- Testing
- Stent therapy of aortic coarctation
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Richard E. Ringel
Catheterization, Complications
Prevalence of Distal Radial Artery Occlusion in Cardiovascular Catheterization Via Distal Radial Access
Explore the prevalence of distal radial artery occlusion after cardiac catheterization via distal radial artery and the risk factors
- Conditions
- Catheterization, Complications, Distal Radial Artery
- Trial name
- NCT05317533
- Testing
- cardiac catheterization via distal radial artery
- Where
- China
- Volunteers
- 805 people
- Sponsor
- Wujin People's Hospital
Pulmonary Hypertension, Sickle Cell Anemia
A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET Study
This study will assess the safety and efficacy of bosentan therapy (in a study known as ASSET) for patients who have high blood pressure in the lungs associated with sickle cell disease.
- Trial name
- ASSET-3 (NCT00360087)
- Testing
- Bosentan
- Volunteers
- 236 people
- Sponsor
- Actelion
Heart Diseases, Heart Failure, Congestive
Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE)
To compare the efficacy of Pulmonary Artery Catheterization (PAC)-directed treatment strategy to a non-invasive treatment strategy on morbidity and mortality in patients with severe, class IV New York Heart Association (NYHA)…
- Conditions
- Heart Diseases, Heart Failure, Congestive, Heart Failure
- Trial name
- NCT00000619
- Testing
- catheterization, Swan-Ganz
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Contrast Induced Nephropathy, Acute Renal Failure
Cystatin C as an Early Marker of Contrast-Medium Nephropathy in Cardiac Catheterization Patients
Hypothesis: Cystatin C compared with creatinine is a better and earlier marker of contrast-induced nephropathy in high and intermedium risk cardiac catheterization patients.
- Trial name
- NCT00467311
- Where
- Mexico
- Volunteers
- 66 people
- Sponsor
- National Heart Institute, Mexico
Kidney Diseases, Diabetes Mellitus
Efficacy and Safety of Alprostadil Prevent Contrast Induced Nephropathy
The aim of this prospective, randomized, controlled study is to investigate the effect of pretreatment with intravenous Alprostadil on the incidence of CIN in a high-risk population of patients with both type 2 diabetes mellitus…
- Conditions
- Kidney Diseases, Diabetes Mellitus, Acute Kidney Injury, Kidney Failure, Chronic
- Trial name
- NCT01722513
- Testing
- Alprostadil ﹠control
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Right Ventricular Dysfunction
Incidence, Impact and Mechanisms of Perioperative Right VEntricular Dysfunction (IMPRoVE)
A study to see how common right heart failure (right ventricular dysfunction) after major surgery is, and to investigate if right ventricular dysfunction causes worse patient outcomes after surgery.
- Trial name
- IMPRoVE (NCT05827315)
- Testing
- Echocardiography, T1 Cardiovascular Magnetic Resonance, Right heart catheterisation and coronary sinus blood sampling
- Where
- 3 sites in United Kingdom
- Volunteers
- 175 people
- Sponsor
- NHS National Waiting Times Centre Board
Diastolic Heart Failure
Study of Nesiritide in Diastolic Heart Failure.
We hypothesize that nesiritide will have favorable effect in decreasing heart filling pressures and echocardiogram studies.
- Trial name
- NCT00309868
- Testing
- neseritide
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Anesthesia, Local
RAOLA Observational: Local Anesthesia During Cardiac Catheterization
An open label observational clinical study to compare the efficacy of EMLA cream (lidocaine 2.5% and prilocaine 2.5% in a ratio of 1:1 by weight) in comparison to the established local anesthesia (LA) protocol of lidocaine…
- Trial name
- NCT03091049
- Where
- Greece
- Volunteers
- 800 people
- Sponsor
- Hippocration General Hospital
Cardiac Surgery in Adult Patient, Cardiac Surgery
Direct vs. Seldinger Technique for Ultrasound-Guided Difficult Radial Access in Cardiac Surgery
Radial artery cannulation is a routine procedure for invasive hemodynamic monitoring for patients undergoing cardiovascular surgery patients.
- Conditions
- Cardiac Surgery in Adult Patient, Cardiac Surgery, Radial Artery Cannulation, Arterial Cannulation
- Trial name
- NCT07400627
- Testing
- Ultrasound-Guided Direct Cannulation Technique, Ultrasound-Guided Seldinger Cannulation Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 242 people
- Sponsor
- Diskapi Teaching and Research Hospital